TITINdb

Map SAVs to Structure

The data displayed in the table aims to be as complete as possible and contains information for all available sources including different versions of the same source, for example, different sources of gnomAD. To avoid seeing multiple entries for the same variant, we recommend to sort by Source first.

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
8736	1	P/L	1	rs1444367941	0.1549	None	gnomAD-3.1.2	6.57E-06
8736	1	P/S	1	rs777166872	0.1549	None	gnomAD-3.1.2	6.57E-06
8736	1	P/S	1	rs777166872	0.1549	None	gnomAD-4.0.0	1.2548E-06
8736	1	P/T	1	rs777166872	0.1549	None	gnomAD-2.1.1	1.26E-05
8736	1	P/T	1	rs777166872	0.1549	None	gnomAD-4.0.0	2.77438E-06
8737	2	R/K	2	rs769711887	0.4902	None	gnomAD-2.1.1	4.19E-06
8737	2	R/K	2	rs769711887	0.4902	None	gnomAD-4.0.0	6.9355E-07
8738	3	F/I	3	rs1335039200	0.1191	None	gnomAD-2.1.1	1.24E-05
8738	3	F/I	3	rs1335039200	0.1191	None	gnomAD-3.1.2	6.57E-06
8738	3	F/I	3	rs1335039200	0.1191	None	gnomAD-4.0.0	1.12549E-05
8738	3	F/S	3	rs1304792247	0.1191	None	gnomAD-4.0.0	1.62391E-06
8739	4	V/L	4	None	0.4840	None	gnomAD-4.0.0	1.61987E-06
8741	6	K/E	7	rs538959125	0.5372	None	gnomAD-2.1.1	1.78299E-04
8741	6	K/E	7	rs538959125	0.5372	None	gnomAD-3.1.2	9.2E-05
8741	6	K/E	7	rs538959125	0.5372	None	1000 genomes	3.99361E-04
8741	6	K/E	7	rs538959125	0.5372	None	gnomAD-4.0.0	3.2426E-05
8741	6	K/Q	7	None	0.5372	None	gnomAD-4.0.0	6.89001E-07
8742	7	L/P	8	rs1302096327	0.2303	None	gnomAD-2.1.1	4.07E-06
8742	7	L/P	8	rs1302096327	0.2303	None	gnomAD-4.0.0	7.56262E-06
8743	8	S/G	9	rs997483780	0.5594	None	gnomAD-4.0.0	4.12439E-06
8743	8	S/N	9	None	0.5594	None	gnomAD-4.0.0	1.60822E-06
8744	9	D/G	11	rs189391840	0.9105	None	gnomAD-2.1.1	2.03E-05
8744	9	D/G	11	rs189391840	0.9105	None	gnomAD-3.1.2	2.63E-05
8744	9	D/G	11	rs189391840	0.9105	None	1000 genomes	5.99042E-04
8744	9	D/G	11	rs189391840	0.9105	None	gnomAD-4.0.0	4.97728E-06
8745	10	I/M	13	rs2077168515	0.5884	None	gnomAD-3.1.2	6.57E-06
8745	10	I/M	13	rs2077168515	0.5884	None	gnomAD-4.0.0	6.5716E-06
8745	10	I/T	13	rs1176501015	0.5884	None	gnomAD-2.1.1	4.04E-06
8745	10	I/T	13	rs1176501015	0.5884	None	gnomAD-4.0.0	1.5968E-06
8745	10	I/V	13	rs901437058	0.5884	None	gnomAD-3.1.2	1.31E-05
8745	10	I/V	13	rs901437058	0.5884	None	gnomAD-4.0.0	1.31328E-05
8746	11	S/P	14	None	0.3312	None	gnomAD-4.0.0	1.59661E-06
8748	13	V/A	18	rs1362528703	0.2054	None	gnomAD-2.1.1	7.16E-06
8748	13	V/A	18	rs1362528703	0.2054	None	gnomAD-3.1.2	6.58E-06
8748	13	V/A	18	rs1362528703	0.2054	None	gnomAD-4.0.0	3.10035E-06
8748	13	V/I	18	rs1456259621	0.2054	None	gnomAD-2.1.1	4.04E-06
8748	13	V/I	18	rs1456259621	0.2054	None	gnomAD-3.1.2	6.57E-06
8748	13	V/I	18	rs1456259621	0.2054	None	gnomAD-4.0.0	2.56537E-06
8748	13	V/L	18	None	0.2054	None	gnomAD-4.0.0	1.5936E-06
8749	14	V/A	23	rs770874023	0.8071	None	gnomAD-2.1.1	3.63E-05
8749	14	V/A	23	rs770874023	0.8071	None	gnomAD-3.1.2	2.63E-05
8749	14	V/A	23	rs770874023	0.8071	None	gnomAD-4.0.0	2.72796E-05
8749	14	V/I	23	rs16866457	0.8071	None	gnomAD-2.1.1	5.20363E-03
8749	14	V/I	23	rs16866457	0.8071	None	gnomAD-3.1.2	1.249E-02
8749	14	V/I	23	rs16866457	0.8071	None	1000 genomes	1.61741E-02
8749	14	V/I	23	rs16866457	0.8071	None	gnomAD-4.0.0	3.01617E-03
8750	15	G/C	24	rs757423560	0.3750	None	gnomAD-2.1.1	4.03E-06
8750	15	G/C	24	rs757423560	0.3750	None	gnomAD-4.0.0	6.84531E-07
8750	15	G/S	24	None	0.3750	None	gnomAD-4.0.0	6.84531E-07
8752	17	E/A	26	None	0.4633	None	gnomAD-4.0.0	1.59258E-06
8752	17	E/K	26	None	0.4633	None	gnomAD-4.0.0	6.84474E-07
8753	18	V/G	28	rs867579263	0.3655	None	gnomAD-4.0.0	5.4756E-06
8753	18	V/I	28	rs373070956	0.3655	None	gnomAD-2.1.1	4.03E-06
8753	18	V/I	28	rs373070956	0.3655	None	gnomAD-3.1.2	6.57E-06
8753	18	V/I	28	rs373070956	0.3655	None	gnomAD-4.0.0	6.57367E-06
8754	19	Q/H	29	rs764746720	0.6505	None	gnomAD-2.1.1	4.03E-06
8754	19	Q/H	29	rs764746720	0.6505	None	gnomAD-3.1.2	6.57E-06
8754	19	Q/H	29	rs764746720	0.6505	None	gnomAD-4.0.0	5.57899E-06
8755	20	L/R	30	None	0.2354	None	gnomAD-4.0.0	1.59232E-06
8756	21	Q/H	31	rs776025006	0.4193	None	gnomAD-2.1.1	4.03E-06
8756	21	Q/H	31	rs776025006	0.4193	None	gnomAD-4.0.0	1.5923E-06
8756	21	Q/R	31	rs761090454	0.4193	None	gnomAD-2.1.1	4.03E-06
8757	22	T/A	33	None	0.0923	None	gnomAD-4.0.0	1.20033E-06
8757	22	T/I	33	rs1357129552	0.0923	None	gnomAD-4.0.0	6.84407E-07
8757	22	T/N	33	None	0.0923	None	gnomAD-4.0.0	6.84407E-07
8757	22	T/S	33	None	0.0923	None	gnomAD-4.0.0	6.84407E-07
8759	24	I/M	35	None	0.0709	None	gnomAD-4.0.0	1.59203E-06
8759	24	I/T	35	rs199918663	0.0709	None	gnomAD-2.1.1	2.86E-05
8759	24	I/T	35	rs199918663	0.0709	None	gnomAD-3.1.2	1.31E-05
8759	24	I/T	35	rs199918663	0.0709	None	gnomAD-4.0.0	2.29343E-05
8759	24	I/V	35	rs1317485542	0.0709	None	gnomAD-2.1.1	1.43E-05
8759	24	I/V	35	rs1317485542	0.0709	None	gnomAD-3.1.2	1.31E-05
8759	24	I/V	35	rs1317485542	0.0709	None	gnomAD-4.0.0	8.97144E-06
8760	25	E/K	38	rs2077161238	0.3516	None	gnomAD-4.0.0	1.77937E-05
8761	26	G/S	40	rs369385294	0.3471	None	gnomAD-2.1.1	5.37E-05
8761	26	G/S	40	rs369385294	0.3471	None	gnomAD-3.1.2	5.26E-05
8761	26	G/S	40	rs369385294	0.3471	None	gnomAD-4.0.0	1.41941E-04
8762	27	A/T	41	rs1336984327	0.5721	None	gnomAD-2.1.1	4.03E-06
8762	27	A/T	41	rs1336984327	0.5721	None	gnomAD-3.1.2	1.32E-05
8762	27	A/T	41	rs1336984327	0.5721	None	gnomAD-4.0.0	9.29769E-06
8762	27	A/V	41	None	0.5721	None	gnomAD-4.0.0	1.59196E-06
8763	28	E/A	42	rs1453342840	0.7787	None	gnomAD-2.1.1	6.37E-05
8763	28	E/A	42	rs1453342840	0.7787	None	gnomAD-3.1.2	1.97E-05
8763	28	E/A	42	rs1453342840	0.7787	None	gnomAD-4.0.0	1.97174E-05
8764	29	P/S	43	None	0.6546	None	gnomAD-4.0.0	2.7373E-06
8764	29	P/T	43	None	0.6546	None	gnomAD-4.0.0	6.84326E-07
8765	30	I/T	44	rs768619883	0.1538	None	gnomAD-2.1.1	2.02E-05
8765	30	I/T	44	rs768619883	0.1538	None	gnomAD-3.1.2	6.57E-06
8765	30	I/T	44	rs768619883	0.1538	None	gnomAD-4.0.0	1.28144E-05
8765	30	I/V	44	rs776531934	0.1538	None	gnomAD-2.1.1	4.03E-06
8765	30	I/V	44	rs776531934	0.1538	None	gnomAD-4.0.0	1.59174E-06
8766	31	S/L	45	rs1368458893	0.4642	None	gnomAD-2.1.1	4.03E-06
8766	31	S/L	45	rs1368458893	0.4642	None	gnomAD-4.0.0	1.5918E-06
8769	34	W/G	48	rs779847107	0.1228	None	gnomAD-4.0.0	4.7901E-06
8770	35	F/S	49	None	0.1393	None	gnomAD-4.0.0	1.59167E-06
8770	35	F/V	49	rs2077156183	0.1393	None	gnomAD-3.1.2	6.57E-06
8770	35	F/V	49	rs2077156183	0.1393	None	gnomAD-4.0.0	6.57324E-06
8771	36	K/R	50	None	0.2510	None	gnomAD-4.0.0	1.59165E-06
8772	37	D/V	51	None	0.3957	None	gnomAD-4.0.0	1.20033E-06
8772	37	D/Y	51	None	0.3957	None	gnomAD-4.0.0	1.20033E-06
8773	38	K/N	52	None	0.7553	None	gnomAD-4.0.0	3.42147E-06
8774	39	G/E	55	None	0.2739	None	gnomAD-4.0.0	6.84279E-07
8775	40	E/A	56	rs758590305	0.4034	None	gnomAD-2.1.1	4.03E-06
8775	40	E/A	56	rs758590305	0.4034	None	gnomAD-4.0.0	1.59164E-06
8775	40	E/D	56	None	0.4034	None	gnomAD-4.0.0	1.20033E-06
8776	41	I/L	57	rs746071731	0.1580	None	gnomAD-2.1.1	4.03E-06
8776	41	I/L	57	rs746071731	0.1580	None	gnomAD-4.0.0	1.59158E-06
8776	41	I/M	57	None	0.1580	None	gnomAD-4.0.0	6.84287E-07
8776	41	I/V	57	rs746071731	0.1580	None	gnomAD-2.1.1	8.07E-06
8776	41	I/V	57	rs746071731	0.1580	None	gnomAD-3.1.2	6.57E-06
8776	41	I/V	57	rs746071731	0.1580	None	gnomAD-4.0.0	5.1251E-06
8777	42	V/D	58	None	0.4917	None	gnomAD-4.0.0	1.59157E-06
8777	42	V/F	58	rs376823283	0.4917	None	gnomAD-2.1.1	8.07E-06
8777	42	V/F	58	rs376823283	0.4917	None	gnomAD-4.0.0	2.73711E-06
8777	42	V/I	58	None	0.4917	None	gnomAD-2.1.1	6.8E-05
8777	42	V/I	58	None	0.4917	None	gnomAD-3.1.2	1.44585E-04
8777	42	V/I	58	None	0.4917	None	gnomAD-4.0.0	1.19612E-04
8777	42	V/L	58	rs376823283	0.4917	None	gnomAD-3.1.2	6.57E-06
8777	42	V/L	58	rs376823283	0.4917	None	gnomAD-4.0.0	1.85925E-06
8778	43	R/K	59	rs1486145907	0.8228	None	gnomAD-3.1.2	1.31E-05
8778	43	R/K	59	rs1486145907	0.8228	None	gnomAD-4.0.0	8.05664E-06
8778	43	R/S	59	rs754011566	0.8228	None	gnomAD-2.1.1	4.03E-06
8778	43	R/T	59	rs1486145907	0.8228	None	gnomAD-2.1.1	4.03E-06
8778	43	R/T	59	rs1486145907	0.8228	None	gnomAD-4.0.0	6.84268E-07
8780	45	S/G	73	None	0.2531	None	gnomAD-4.0.0	2.40064E-06
8780	45	S/N	73	rs764652580	0.2531	None	gnomAD-2.1.1	4.03E-06
8780	45	S/N	73	rs764652580	0.2531	None	gnomAD-4.0.0	1.77904E-05
8780	45	S/R	73	rs756708089	0.2531	None	gnomAD-2.1.1	4.03E-06
8780	45	S/R	73	rs756708089	0.2531	None	gnomAD-4.0.0	1.59146E-06
8781	46	D/A	111	rs2077152071	0.6046	None	gnomAD-3.1.2	6.57E-06
8781	46	D/A	111	rs2077152071	0.6046	None	gnomAD-4.0.0	6.57168E-06
8781	46	D/N	111	None	0.6046	None	gnomAD-4.0.0	6.00161E-06
8782	47	N/S	115	rs727504895	0.3130	None	gnomAD-4.0.0	1.36848E-06
8782	47	N/Y	115	rs1017848590	0.3130	None	gnomAD-3.1.2	1.31E-05
8782	47	N/Y	115	rs1017848590	0.3130	None	gnomAD-4.0.0	9.29567E-06
8783	48	I/K	121	rs1226202295	0.0825	None	gnomAD-3.1.2	6.57E-06
8783	48	I/K	121	rs1226202295	0.0825	None	gnomAD-4.0.0	6.57082E-06
8783	48	I/L	121	None	0.0825	None	gnomAD-4.0.0	6.84237E-07
8783	48	I/M	121	rs767996372	0.0825	None	gnomAD-2.1.1	4.03E-06
8783	48	I/M	121	rs767996372	0.0825	None	gnomAD-4.0.0	6.15819E-06
8783	48	I/T	121	rs1226202295	0.0825	None	gnomAD-2.1.1	4.03E-06
8783	48	I/T	121	rs1226202295	0.0825	None	gnomAD-4.0.0	1.36848E-06
8783	48	I/V	121	rs2077150875	0.0825	None	gnomAD-4.0.0	4.78966E-06
8784	49	W/R	122	rs375067750	0.7364	None	gnomAD-2.1.1	1.21E-05
8784	49	W/R	122	rs375067750	0.7364	None	gnomAD-3.1.2	1.97E-05
8784	49	W/R	122	rs375067750	0.7364	None	gnomAD-4.0.0	1.30137E-05
8785	50	I/F	123	rs2077149198	0.2581	None	gnomAD-4.0.0	3.18283E-06
8786	51	S/A	125	None	0.3621	None	gnomAD-4.0.0	1.20032E-06
8787	52	Y/C	127	rs1365431842	0.2777	None	gnomAD-2.1.1	8.07E-06
8787	52	Y/C	127	rs1365431842	0.2777	None	gnomAD-4.0.0	2.05272E-06
8787	52	Y/F	127	None	0.2777	None	gnomAD-4.0.0	6.8424E-07
8790	55	N/D	134	rs772728050	0.5289	None	gnomAD-2.1.1	2.15E-05
8790	55	N/D	134	rs772728050	0.5289	None	gnomAD-3.1.2	6.57E-06
8790	55	N/D	134	rs772728050	0.5289	None	gnomAD-4.0.0	2.47876E-06
8791	56	I/F	135	None	0.1420	None	gnomAD-4.0.0	1.20032E-06
8792	57	A/E	136	rs761198294	0.0711	None	gnomAD-2.1.1	4.03E-06
8792	57	A/E	136	rs761198294	0.0711	None	gnomAD-3.1.2	2.63E-05
8792	57	A/E	136	rs761198294	0.0711	None	gnomAD-4.0.0	4.33802E-06
8792	57	A/S	136	rs764989717	0.0711	None	gnomAD-2.1.1	4.03E-06
8792	57	A/S	136	rs764989717	0.0711	None	gnomAD-3.1.2	6.57E-06
8792	57	A/S	136	rs764989717	0.0711	None	gnomAD-4.0.0	2.5623E-06
8793	58	T/A	137	rs776154251	0.2091	None	gnomAD-2.1.1	5.37E-05
8793	58	T/A	137	rs776154251	0.2091	None	gnomAD-3.1.2	1.97E-05
8793	58	T/A	137	rs776154251	0.2091	None	gnomAD-4.0.0	1.54926E-05
8794	59	L/I	138	None	0.0562	None	gnomAD-2.1.1	4.03E-06
8794	59	L/I	138	None	0.0562	None	gnomAD-3.1.2	1.97E-05
8794	59	L/I	138	None	0.0562	None	gnomAD-4.0.0	3.09861E-06
8794	59	L/V	138	rs372229450	0.0562	None	gnomAD-2.1.1	2.5E-05
8794	59	L/V	138	rs372229450	0.0562	None	gnomAD-3.1.2	1.97E-05
8794	59	L/V	138	rs372229450	0.0562	None	1000 genomes	1.99681E-04
8794	59	L/V	138	rs372229450	0.0562	None	gnomAD-4.0.0	1.79706E-05
8795	60	Q/E	139	None	0.5322	None	gnomAD-4.0.0	1.20032E-06
8795	60	Q/R	139	None	0.5322	None	gnomAD-4.0.0	1.59134E-06
8796	61	F/C	140	None	0.1576	None	gnomAD-4.0.0	3.42113E-06
8796	61	F/L	140	rs1193918191	0.1576	None	gnomAD-2.1.1	4.03E-06
8796	61	F/L	140	rs1193918191	0.1576	None	gnomAD-4.0.0	1.59133E-06
8797	62	S/A	141	None	0.2623	None	gnomAD-4.0.0	1.20032E-06
8798	63	R/K	143	None	0.8256	None	gnomAD-4.0.0	6.84225E-07
8798	63	R/T	143	rs771748059	0.8256	None	gnomAD-2.1.1	3.22E-05
8798	63	R/T	143	rs771748059	0.8256	None	gnomAD-3.1.2	6.57E-06
8798	63	R/T	143	rs771748059	0.8256	None	gnomAD-4.0.0	3.03658E-05
8799	64	V/M	144	rs1560601919	0.1336	None	gnomAD-4.0.0	6.15807E-06
8801	66	P/A	146	rs1220132171	0.5299	None	gnomAD-2.1.1	4.03E-06
8801	66	P/A	146	rs1220132171	0.5299	None	gnomAD-4.0.0	3.18267E-06
8801	66	P/L	146	rs778967914	0.5299	None	gnomAD-2.1.1	8.05E-06
8801	66	P/L	146	rs778967914	0.5299	None	gnomAD-4.0.0	4.10536E-06
8801	66	P/T	146	None	0.5299	None	gnomAD-4.0.0	3.18267E-06
8802	67	A/D	148	rs1292226345	0.3668	None	gnomAD-2.1.1	4.03E-06
8802	67	A/D	148	rs1292226345	0.3668	None	gnomAD-4.0.0	1.59134E-06
8803	68	N/S	149	rs12693164	0.2328	None	gnomAD-2.1.1	1.77519E-01
8803	68	N/S	149	rs12693164	0.2328	None	gnomAD-3.1.2	1.68341E-01
8803	68	N/S	149	rs12693164	0.2328	None	1000 genomes	2.47005E-01
8803	68	N/S	149	rs12693164	0.2328	None	gnomAD-4.0.0	1.64667E-01
8804	69	A/P	151	rs778012263	0.2411	None	gnomAD-3.1.2	6.57E-06
8804	69	A/P	151	rs778012263	0.2411	None	gnomAD-4.0.0	1.85913E-06
8804	69	A/S	151	rs778012263	0.2411	None	gnomAD-2.1.1	4.03E-06
8805	70	G/R	152	rs756620595	0.1962	None	gnomAD-2.1.1	4.03E-06
8805	70	G/R	152	rs756620595	0.1962	None	gnomAD-4.0.0	1.59136E-06
8808	73	T/A	155	None	0.1269	None	gnomAD-4.0.0	1.20033E-06
8809	74	C/R	156	rs753253530	0.0638	None	gnomAD-2.1.1	4.02E-06
8810	75	Q/H	157	rs781752797	0.2519	None	gnomAD-2.1.1	8.05E-06
8810	75	Q/H	157	rs781752797	0.2519	None	gnomAD-4.0.0	9.57938E-06
8810	75	Q/L	157	rs934473433	0.2519	None	gnomAD-2.1.1	4.02E-06
8810	75	Q/L	157	rs934473433	0.2519	None	gnomAD-3.1.2	6.57E-06
8810	75	Q/L	157	rs934473433	0.2519	None	gnomAD-4.0.0	5.12471E-06
8811	76	I/V	158	rs1346764958	0.0417	None	gnomAD-2.1.1	4.02E-06
8811	76	I/V	158	rs1346764958	0.0417	None	gnomAD-4.0.0	4.8013E-06
8813	78	N/S	161	rs2077136991	0.1610	None	gnomAD-4.0.0	1.5916E-06
8814	79	D/N	162	rs1035364658	0.7902	None	gnomAD-2.1.1	4.02E-06
8814	79	D/N	162	rs1035364658	0.7902	None	gnomAD-4.0.0	1.59175E-06
8814	79	D/Y	162	rs1035364658	0.7902	None	gnomAD-3.1.2	6.57E-06
8814	79	D/Y	162	rs1035364658	0.7902	None	gnomAD-4.0.0	6.57315E-06
8815	80	A/G	163	rs1168744166	0.5762	None	gnomAD-2.1.1	7.15E-06
8815	80	A/G	163	rs1168744166	0.5762	None	gnomAD-3.1.2	1.31E-05
8815	80	A/G	163	rs1168744166	0.5762	None	gnomAD-4.0.0	8.96895E-06
8815	80	A/V	163	rs1168744166	0.5762	None	gnomAD-2.1.1	4.02E-06
8815	80	A/V	163	rs1168744166	0.5762	None	gnomAD-4.0.0	3.18348E-06
8817	82	M/I	165	rs1427255919	0.5214	None	gnomAD-2.1.1	8.05E-06
8817	82	M/I	165	rs1427255919	0.5214	None	gnomAD-4.0.0	3.18436E-06
8817	82	M/T	165	rs1469529188	0.5214	None	gnomAD-2.1.1	4.02E-06
8817	82	M/T	165	rs1469529188	0.5214	None	gnomAD-4.0.0	9.58085E-06
8817	82	M/V	165	rs878856898	0.5214	None	gnomAD-4.0.0	1.5918E-06
8818	83	Q/K	166	rs2077133872	0.3440	None	gnomAD-3.1.2	6.58E-06
8818	83	Q/K	166	rs2077133872	0.3440	None	gnomAD-4.0.0	2.56377E-06
8819	84	E/D	168	rs1242327696	0.2231	None	gnomAD-2.1.1	1.91058E-04
8819	84	E/D	168	rs1242327696	0.2231	None	gnomAD-3.1.2	4.6E-05
8819	84	E/D	168	rs1242327696	0.2231	None	gnomAD-4.0.0	4.60109E-05
8819	84	E/K	168	rs1452521377	0.2231	None	gnomAD-4.0.0	2.73754E-06
8820	85	C/G	169	rs1193461740	0.1057	None	gnomAD-3.1.2	6.58E-06
8820	85	C/G	169	rs1193461740	0.1057	None	gnomAD-4.0.0	6.57592E-06
8820	85	C/Y	169	rs778500616	0.1057	None	gnomAD-2.1.1	4.02E-06
8820	85	C/Y	169	rs778500616	0.1057	None	gnomAD-4.0.0	1.59325E-06
8822	87	A/S	172	None	0.1575	None	gnomAD-4.0.0	2.73873E-06
8822	87	A/T	172	rs184883436	0.1575	None	gnomAD-2.1.1	9.29E-05
8822	87	A/T	172	rs184883436	0.1575	None	gnomAD-3.1.2	4.6E-05
8822	87	A/T	172	rs184883436	0.1575	None	gnomAD-4.0.0	5.76658E-05
8822	87	A/V	172	rs753291479	0.1575	None	gnomAD-2.1.1	4.02E-06
8822	87	A/V	172	rs753291479	0.1575	None	gnomAD-4.0.0	1.57463E-05
8823	88	T/K	173	rs368151971	0.3539	None	gnomAD-2.1.1	4.03E-06
8823	88	T/K	173	rs368151971	0.3539	None	gnomAD-4.0.0	6.84809E-07
8823	88	T/M	173	rs368151971	0.3539	None	gnomAD-2.1.1	2.01E-05
8823	88	T/M	173	rs368151971	0.3539	None	gnomAD-3.1.2	5.92E-05
8823	88	T/M	173	rs368151971	0.3539	None	1000 genomes	1.99681E-04
8823	88	T/M	173	rs368151971	0.3539	None	gnomAD-4.0.0	1.98452E-05
8823	88	T/R	173	None	0.3539	None	gnomAD-4.0.0	6.84809E-07
8824	89	L/I	174	rs1322441627	0.2169	None	gnomAD-2.1.1	3.19E-05
8824	89	L/I	174	rs1322441627	0.2169	None	gnomAD-3.1.2	6.57E-06
8824	89	L/I	174	rs1322441627	0.2169	None	gnomAD-4.0.0	6.57263E-06
8825	90	S/F	175	rs2077128629	0.3264	None	gnomAD-4.0.0	1.59566E-06
8826	91	V/I	178	rs200116046	0.2751	None	gnomAD-2.1.1	4.03E-06
8826	91	V/I	178	rs200116046	0.2751	None	gnomAD-4.0.0	2.74088E-06

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
8736	1	P/L	rs1444367941	0.1549	gnomAD-3.1.2	1	None	0.5805	0.8337	32.0	D	None	-1.44	0.058215	-0.702	0.7975	0.791	0.469722267271	None	1.0	0.807	0.920603051264	1.0	0.567016839981	-5.87	0.68	0.879	0.097	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
8736	1	P/S	rs777166872	0.1549	gnomAD-3.1.2	1	None	0.8325	0.9428	24.3	D	None	-1.43	0.105437	-2.18	0.8172	0.8665	0.467212021082	None	0.999986	0.803	0.723536994813	1.0	0.507382810116	-4.74	0.732	0.893	0.031	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07727E-04	0	None	N	None
8736	1	P/S	rs777166872	0.1549	gnomAD-4.0.0	1	None	0.8325	0.9428	24.3	D	None	-1.43	0.105437	-2.18	0.8172	0.8665	0.467212021082	None	0.999986	0.803	0.723536994813	1.0	0.507382810116	-4.74	0.732	0.893	0.031	None	None	1.2548E-06	0	0	0	0	None	0	0	1.2548E-06	8.55835E-07	1.13253E-05	0	None	N	None
8736	1	P/T	rs777166872	0.1549	gnomAD-2.1.1	1	None	0.7676	0.924	24.1	D	-2.077	-1.44	0.113406	-1.946	0.8172	0.8665	0.489810199868	None	0.999677	0.808	0.859303954879	1.0	0.535619795322	-4.66	0.719	0.888	0.016	None	None	1.26E-05	0	0	0	0	None	3.59E-05	None	1.26E-05	0	9.13E-06	1.74216E-04	None	N	None
8736	1	P/T	rs777166872	0.1549	gnomAD-4.0.0	1	None	0.7676	0.924	24.1	D	-2.077	-1.44	0.113406	-1.946	0.8172	0.8665	0.489810199868	None	0.999677	0.808	0.859303954879	1.0	0.535619795322	-4.66	0.719	0.888	0.016	None	None	2.77438E-06	0	0	0	0	None	0	0	2.77438E-06	9.08726E-07	2.39567E-05	1.6822E-05	None	N	None
8737	2	R/K	rs769711887	0.4902	gnomAD-2.1.1	2	None	0.0802	0.0854	16.38	N	-0.113	-0.16	0.012806	-0.336	0.1768	-0.8368	0.0842569272004	None	1.0	0.502	0.225902525712	None	0.248125866055	-1.03	0.159	0.092	0.409	None	None	4.19E-06	0	0	0	5.7E-05	None	0	None	4.19E-06	0	0	0	None	N	None
8737	2	R/K	rs769711887	0.4902	gnomAD-4.0.0	2	None	0.0802	0.0854	16.38	N	-0.113	-0.16	0.012806	-0.336	0.1768	-0.8368	0.0842569272004	None	1.0	0.502	0.225902525712	None	0.248125866055	-1.03	0.159	0.092	0.409	None	None	6.9355E-07	0	0	0	0	None	0	0	6.9355E-07	9.08698E-07	0	0	None	N	None
8738	3	F/I	rs1335039200	0.1191	gnomAD-2.1.1	3	None	0.3658	0.5199	25.4	N	-2.089	-0.38	0.039436	-1.698	0.4936	0.0345	0.544725754754	None	0.972123	0.741	0.497613835824	1.0	0.682124137878	-3.64	0.663	0.771	0.02	None	None	1.24E-05	0	0	0	1.1302E-04	None	0	None	1.24E-05	4.85E-05	0	0	None	N	None
8738	3	F/I	rs1335039200	0.1191	gnomAD-3.1.2	3	None	0.3658	0.5199	25.4	N	-2.089	-0.38	0.039436	-1.698	0.4936	0.0345	0.544725754754	None	0.972123	0.741	0.497613835824	1.0	0.682124137878	-3.64	0.663	0.771	0.02	None	None	6.57E-06	0	0	0	1.92976E-04	None	0	0	6.57E-06	0	0	0	None	N	None
8738	3	F/I	rs1335039200	0.1191	gnomAD-4.0.0	3	None	0.3658	0.5199	25.4	N	-2.089	-0.38	0.039436	-1.698	0.4936	0.0345	0.544725754754	None	0.972123	0.741	0.497613835824	1.0	0.682124137878	-3.64	0.663	0.771	0.02	None	None	1.12549E-05	0	0	0	4.03932E-04	None	0	0	1.12549E-05	0	0	0	None	N	None
8738	3	F/S	rs1304792247	0.1191	gnomAD-4.0.0	3	None	0.8659	0.9537	33.0	D	None	-0.7	0.130664	-2.657	0.6612	0.574	0.61613149071	None	0.982825	0.696	0.887337171484	1.0	0.68090569973	-5.02	0.753	0.847	0.005	None	None	1.62391E-06	0	2.32428E-05	0	0	None	0	0	1.62391E-06	0	0	0	None	N	None
8739	4	V/L	None	0.4840	gnomAD-4.0.0	4	None	0.1135	0.1453	23.0	N	None	1.06	0.03068	-0.495	0.0977	-1.0002	0.0821069030307	None	1.0	0.585	0.226586394389	None	0.590929746628	-1.84	0.073	0.119	0.084	None	None	1.61987E-06	0	0	0	0	None	0	0	1.61987E-06	0	0	3.07012E-05	None	N	None
8741	6	K/E	rs538959125	0.5372	gnomAD-2.1.1	7	None	0.2785	0.4112	23.4	D	0.578	-0.29	0.057574	0.513	0.3098	-0.5317	0.185059521098	None	0.969029	0.548	0.3691244813	0.114	0.45890802145	-2.27	0.279	0.547	0.283	None	None	1.78299E-04	0	0	0	2.53676E-03	None	0	None	1.78299E-04	0	0	0	None	I	None
8741	6	K/E	rs538959125	0.5372	gnomAD-3.1.2	7	None	0.2785	0.4112	23.4	D	0.578	-0.29	0.057574	0.513	0.3098	-0.5317	0.185059521098	None	0.969029	0.548	0.3691244813	0.114	0.45890802145	-2.27	0.279	0.547	0.283	None	None	9.2E-05	0	6.55E-05	0	2.50675E-03	None	0	0	9.2E-05	0	0	0	None	I	None
8741	6	K/E	rs538959125	0.5372	1000 genomes	7	None	0.2785	0.4112	23.4	D	0.578	-0.29	0.057574	0.513	0.3098	-0.5317	0.185059521098	None	0.969029	0.548	0.3691244813	0.114	0.45890802145	-2.27	0.279	0.547	0.283	None	None	3.99361E-04	0	0	None	2E-03	0	None	None	3.99361E-04	None	0	None	None	I	None
8741	6	K/E	rs538959125	0.5372	gnomAD-4.0.0	7	None	0.2785	0.4112	23.4	D	0.578	-0.29	0.057574	0.513	0.3098	-0.5317	0.185059521098	None	0.969029	0.548	0.3691244813	0.114	0.45890802145	-2.27	0.279	0.547	0.283	None	None	3.2426E-05	0	1.68294E-05	0	1.03042E-03	None	0	0	3.2426E-05	0	0	8.06218E-05	None	I	None
8741	6	K/Q	None	0.5372	gnomAD-4.0.0	7	None	0.169	0.2264	23.2	N	None	-0.3	0.057674	-0.088	0.3324	-0.4247	0.152145718627	None	0.949032	0.597	0.248417906384	0.269	0.431185483932	-2.26	0.344	0.568	0.029	None	None	6.89001E-07	0	0	0	0	None	0	0	6.89001E-07	0	1.17583E-05	0	None	I	None
8742	7	L/P	rs1302096327	0.2303	gnomAD-2.1.1	8	None	0.1048	0.2257	23.7	N	None	1.01	0.023264	-1.209	0.0862	-1.0481	0.137836223077	None	0.999008	0.613	0.592455534737	0.004	0.538607120514	-4.4	0.127	0.497	0.044	None	None	4.07E-06	0	0	0	0	None	0	None	4.07E-06	0	8.96E-06	0	None	N	None
8742	7	L/P	rs1302096327	0.2303	gnomAD-4.0.0	8	None	0.1048	0.2257	23.7	N	None	1.01	0.023264	-1.209	0.0862	-1.0481	0.137836223077	None	0.999008	0.613	0.592455534737	0.004	0.538607120514	-4.4	0.127	0.497	0.044	None	None	7.56262E-06	0	0	0	0	None	0	0	7.56262E-06	8.12838E-06	0	3.33056E-05	None	N	None
8743	8	S/G	rs997483780	0.5594	gnomAD-4.0.0	9	None	0.0679	0.0812	22.1	N	None	-0.33	0.029087	-0.364	0.2775	-0.4884	0.0786160445598	None	0.904976	0.431	0.199424873507	0.008	0.402601242065	-2.6	0.198	0.234	0.408	None	None	4.12439E-06	0	2.25317E-05	0	0	None	0	0	4.12439E-06	3.61209E-06	0	1.66495E-05	None	I	None
8743	8	S/N	None	0.5594	gnomAD-4.0.0	9	None	0.0751	0.0927	17.98	N	None	-0.3	0.030443	-0.169	0.242	-0.7095	0.0777257753559	None	0.989181	0.416	0.166414681773	None	0.463351309299	-1.73	0.147	0.071	0.488	None	None	1.60822E-06	0	0	0	0	None	0	0	1.60822E-06	2.89382E-06	0	0	None	I	None
8744	9	D/G	rs189391840	0.9105	gnomAD-2.1.1	11	None	0.1536	0.2324	None	N	-0.078	None	None	-0.249	None	None	None	None	None	None	None	0.001	None	None	0.319	0.187	None	None	None	2.03E-05	0	0	0	2.80238E-04	None	0	None	2.03E-05	0	0	0	None	I	None
8744	9	D/G	rs189391840	0.9105	gnomAD-3.1.2	11	None	0.1536	0.2324	None	N	-0.078	None	None	-0.249	None	None	None	None	None	None	None	0.001	None	None	0.319	0.187	None	None	None	2.63E-05	0	0	0	7.7101E-04	None	0	0	2.63E-05	0	0	0	None	I	None
8744	9	D/G	rs189391840	0.9105	1000 genomes	11	None	0.1536	0.2324	None	N	-0.078	None	None	-0.249	None	None	None	None	None	None	None	0.001	None	None	0.319	0.187	None	None	None	5.99042E-04	0	0	None	3E-03	0	None	None	5.99042E-04	None	0	None	None	I	None
8744	9	D/G	rs189391840	0.9105	gnomAD-4.0.0	11	None	0.1536	0.2324	None	N	-0.078	None	None	-0.249	None	None	None	None	None	None	None	0.001	None	None	0.319	0.187	None	None	None	4.97728E-06	0	0	0	1.78827E-04	None	0	0	4.97728E-06	0	0	0	None	I	None
8745	10	I/M	rs2077168515	0.5884	gnomAD-3.1.2	13	None	0.0708	0.0747	16.57	N	None	-0.32	0.015012	-0.513	0.1058	-1.0828	0.0848422555487	None	0.987607	0.568	0.151104730317	None	0.259988963604	-0.79	0.153	0.131	0.248	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	I	None
8745	10	I/M	rs2077168515	0.5884	gnomAD-4.0.0	13	None	0.0708	0.0747	16.57	N	None	-0.32	0.015012	-0.513	0.1058	-1.0828	0.0848422555487	None	0.987607	0.568	0.151104730317	None	0.259988963604	-0.79	0.153	0.131	0.248	None	None	6.5716E-06	2.41185E-05	0	0	0	None	0	0	6.5716E-06	0	0	0	None	I	None
8745	10	I/T	rs1176501015	0.5884	gnomAD-2.1.1	13	None	0.08	0.0933	19.85	N	0.164	-0.31	0.024562	-0.924	0.132	-0.9604	0.106484134016	None	1.0	0.595	0.45349784317	None	0.321916699409	-1.73	0.154	0.201	0.223	None	None	4.04E-06	0	2.91E-05	0	0	None	0	None	4.04E-06	0	0	0	None	I	None
8745	10	I/T	rs1176501015	0.5884	gnomAD-4.0.0	13	None	0.08	0.0933	19.85	N	0.164	-0.31	0.024562	-0.924	0.132	-0.9604	0.106484134016	None	1.0	0.595	0.45349784317	None	0.321916699409	-1.73	0.154	0.201	0.223	None	None	1.5968E-06	0	2.29137E-05	0	0	None	0	0	1.5968E-06	0	0	0	None	I	None
8745	10	I/V	rs901437058	0.5884	gnomAD-3.1.2	13	None	0.0601	0.0638	18.01	N	None	-0.02	0.012076	-0.692	0.0745	-1.0267	0.0703051542146	None	1.0	0.408	0.162503812791	None	0.242306664586	-0.02	0.107	0.147	0.745	None	None	1.31E-05	0	0	0	1.92827E-04	None	0	0	1.31E-05	1.47E-05	0	0	None	I	None
8745	10	I/V	rs901437058	0.5884	gnomAD-4.0.0	13	None	0.0601	0.0638	18.01	N	None	-0.02	0.012076	-0.692	0.0745	-1.0267	0.0703051542146	None	1.0	0.408	0.162503812791	None	0.242306664586	-0.02	0.107	0.147	0.745	None	None	1.31328E-05	0	0	0	1.93274E-04	None	0	0	1.31328E-05	1.47029E-05	0	0	None	I	None
8746	11	S/P	None	0.3312	gnomAD-4.0.0	14	None	0.1759	0.2773	23.1	N	None	-0.3	0.052007	-0.158	0.3048	-0.3283	0.236207031682	None	1.0	0.553	0.362758974969	0.956	0.455113351345	-2.78	0.414	0.396	0.031	None	None	1.59661E-06	0	0	0	0	None	0	0	1.59661E-06	0	1.43724E-05	0	None	N	None
8748	13	V/A	rs1362528703	0.2054	gnomAD-2.1.1	18	None	0.0931	0.104	19.19	N	-1.127	-0.16	0.046973	-0.742	0.1919	-0.7882	0.108086438741	None	1.0	0.408	0.446913017954	0.004	0.264901161194	-2.13	0.154	0.581	0.109	None	None	7.16E-06	0	0	0	0	None	0	None	7.16E-06	0	7.83E-06	1.41283E-04	None	N	None
8748	13	V/A	rs1362528703	0.2054	gnomAD-3.1.2	18	None	0.0931	0.104	19.19	N	-1.127	-0.16	0.046973	-0.742	0.1919	-0.7882	0.108086438741	None	1.0	0.408	0.446913017954	0.004	0.264901161194	-2.13	0.154	0.581	0.109	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
8748	13	V/A	rs1362528703	0.2054	gnomAD-4.0.0	18	None	0.0931	0.104	19.19	N	-1.127	-0.16	0.046973	-0.742	0.1919	-0.7882	0.108086438741	None	1.0	0.408	0.446913017954	0.004	0.264901161194	-2.13	0.154	0.581	0.109	None	None	3.10035E-06	0	0	0	0	None	0	0	3.10035E-06	3.39165E-06	0	1.6022E-05	None	N	None
8748	13	V/I	rs1456259621	0.2054	gnomAD-2.1.1	18	None	0.063	0.067	13.47	N	-0.303	-0.22	0.039669	-0.311	0.1828	-0.8783	0.0684251949703	None	1.0	0.454	0.295623431141	None	0.243859678507	0.01	0.102	0.254	0.909	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.91E-06	0	None	N	None
8748	13	V/I	rs1456259621	0.2054	gnomAD-3.1.2	18	None	0.063	0.067	13.47	N	-0.303	-0.22	0.039669	-0.311	0.1828	-0.8783	0.0684251949703	None	1.0	0.454	0.295623431141	None	0.243859678507	0.01	0.102	0.254	0.909	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
8748	13	V/I	rs1456259621	0.2054	gnomAD-4.0.0	18	None	0.063	0.067	13.47	N	-0.303	-0.22	0.039669	-0.311	0.1828	-0.8783	0.0684251949703	None	1.0	0.454	0.295623431141	None	0.243859678507	0.01	0.102	0.254	0.909	None	None	2.56537E-06	1.69268E-05	0	0	0	None	0	0	2.56537E-06	2.39538E-06	0	0	None	N	None
8748	13	V/L	None	0.2054	gnomAD-4.0.0	18	None	0.0906	0.1001	14.16	N	None	-0.2	0.026011	-0.311	0.1087	-0.9926	0.0819424430668	None	1.0	0.382	0.192905019026	None	0.25808390975	-0.92	0.109	0.271	0.332	None	None	1.5936E-06	0	0	0	0	None	0	0	1.5936E-06	2.86159E-06	0	0	None	N	None
8749	14	V/A	rs770874023	0.8071	gnomAD-2.1.1	23	None	0.0653	0.0656	None	N	-0.212	None	None	-1.12	None	None	None	None	None	None	None	None	None	None	0.052	0.139	None	None	None	3.63E-05	0	0	0	0	None	0	None	3.63E-05	9.39E-05	6.23E-05	0	None	I	None
8749	14	V/A	rs770874023	0.8071	gnomAD-3.1.2	23	None	0.0653	0.0656	None	N	-0.212	None	None	-1.12	None	None	None	None	None	None	None	None	None	None	0.052	0.139	None	None	None	2.63E-05	0	0	0	0	None	0	9.49367E-03	2.63E-05	1.47E-05	0	0	None	I	None
8749	14	V/A	rs770874023	0.8071	gnomAD-4.0.0	23	None	0.0653	0.0656	None	N	-0.212	None	None	-1.12	None	None	None	None	None	None	None	None	None	None	0.052	0.139	None	None	None	2.72796E-05	0	1.66789E-05	0	0	None	3.13509E-05	6.6072E-04	2.72796E-05	2.45875E-05	3.29823E-05	8.00743E-05	None	I	None
8749	14	V/I	rs16866457	0.8071	gnomAD-2.1.1	23	None	0.0658	0.0696	None	N	0.002	None	None	-0.548	None	None	None	None	None	None	None	None	None	None	0.042	0.149	None	None	None	5.20363E-03	4.10006E-02	1.61803E-03	3.10138E-02	0	None	9.84E-05	None	5.20363E-03	0	4.69807E-04	3.24767E-03	None	I	None
8749	14	V/I	rs16866457	0.8071	gnomAD-3.1.2	23	None	0.0658	0.0696	None	N	0.002	None	None	-0.548	None	None	None	None	None	None	None	None	None	None	0.042	0.149	None	None	None	1.249E-02	4.10105E-02	3.60419E-03	2.94118E-02	0	None	0	0	1.249E-02	3.82353E-04	0	8.61244E-03	None	I	None
8749	14	V/I	rs16866457	0.8071	1000 genomes	23	None	0.0658	0.0696	None	N	0.002	None	None	-0.548	None	None	None	None	None	None	None	None	None	None	0.042	0.149	None	None	None	1.61741E-02	5.82E-02	5.8E-03	None	0	0	None	None	1.61741E-02	None	0	None	None	I	None
8749	14	V/I	rs16866457	0.8071	gnomAD-4.0.0	23	None	0.0658	0.0696	None	N	0.002	None	None	-0.548	None	None	None	None	None	None	None	None	None	None	0.042	0.149	None	None	None	3.01617E-03	4.22047E-02	2.60156E-03	3.07068E-02	0	None	0	1.32188E-03	3.01617E-03	2.50112E-04	8.7943E-05	5.22084E-03	None	I	None
8750	15	G/C	rs757423560	0.3750	gnomAD-2.1.1	24	None	0.4003	0.5303	20.4	D	-0.635	-1.5	0.07565	-0.897	0.7702	0.8573	0.376481972727	None	0.905711	0.795	0.850572185047	0.983	0.432663083076	-5.49	0.622	0.781	0.004	None	None	4.03E-06	0	0	0	0	None	3.28E-05	None	4.03E-06	0	0	0	None	I	None
8750	15	G/C	rs757423560	0.3750	gnomAD-4.0.0	24	None	0.4003	0.5303	20.4	D	-0.635	-1.5	0.07565	-0.897	0.7702	0.8573	0.376481972727	None	0.905711	0.795	0.850572185047	0.983	0.432663083076	-5.49	0.622	0.781	0.004	None	None	6.84531E-07	0	0	0	0	None	0	0	6.84531E-07	0	1.16077E-05	0	None	I	None
8750	15	G/S	None	0.3750	gnomAD-4.0.0	24	None	0.1283	0.1742	15.29	D	None	-1.46	0.039729	-0.889	0.6247	0.2551	0.145711389982	None	0.675207	0.738	0.403609169532	0.139	0.409883141518	-3.45	0.514	0.718	0.034	None	None	6.84531E-07	0	0	0	0	None	0	0	6.84531E-07	0	0	1.65761E-05	None	I	None
8752	17	E/A	None	0.4633	gnomAD-4.0.0	26	None	0.0819	0.0834	19.33	N	None	0.99	0.012757	-0.743	0.0488	-1.0954	0.0917213970653	None	1.0	0.49	0.0986583533028	0.001	0.325024545193	-2.93	0.11	0.293	0.045	None	None	1.59258E-06	0	0	0	0	None	0	0	1.59258E-06	2.85984E-06	0	0	None	I	None
8752	17	E/K	None	0.4633	gnomAD-4.0.0	26	None	0.0932	0.0987	17.13	N	None	1.01	0.012207	-0.197	0.0708	-1.0106	0.097562478753	None	1.0	0.623	0.134241683229	0.003	0.356375157833	-2.0	0.132	0.317	0.042	None	None	6.84474E-07	0	0	0	0	None	0	0	6.84474E-07	8.99643E-07	0	0	None	I	None
8753	18	V/G	rs867579263	0.3655	gnomAD-4.0.0	28	None	0.1443	0.1699	22.9	N	None	0.68	0.035426	-2.316	0.3438	-0.4033	0.445176780342	None	0.996539	0.579	0.711079051923	0.285	0.367874234915	-4.18	0.307	0.727	0.003	None	None	5.4756E-06	8.97022E-05	0	0	0	None	0	1.73611E-04	5.4756E-06	2.6989E-06	0	1.65733E-05	None	I	None
8753	18	V/I	rs373070956	0.3655	gnomAD-2.1.1	28	None	0.0723	0.0767	None	N	-0.328	None	None	-0.537	None	None	None	None	None	None	None	None	None	None	0.13	0.335	None	None	None	4.03E-06	6.47E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	I	None
8753	18	V/I	rs373070956	0.3655	gnomAD-3.1.2	28	None	0.0723	0.0767	None	N	-0.328	None	None	-0.537	None	None	None	None	None	None	None	None	None	None	0.13	0.335	None	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	I	None
8753	18	V/I	rs373070956	0.3655	gnomAD-4.0.0	28	None	0.0723	0.0767	None	N	-0.328	None	None	-0.537	None	None	None	None	None	None	None	None	None	None	0.13	0.335	None	None	None	6.57367E-06	2.41336E-05	0	0	0	None	0	0	6.57367E-06	0	0	0	None	I	None
8754	19	Q/H	rs764746720	0.6505	gnomAD-2.1.1	29	None	0.1363	0.1517	15.37	N	-0.231	1.03	0.010526	-0.632	0.077	-1.0166	0.0984681205956	None	1.0	0.435	0.0551355673512	0.239	0.320728957653	-2.56	0.122	0.401	0.174	None	None	4.03E-06	0	0	0	0	None	3.28E-05	None	4.03E-06	0	0	0	None	N	None
8754	19	Q/H	rs764746720	0.6505	gnomAD-3.1.2	29	None	0.1363	0.1517	15.37	N	-0.231	1.03	0.010526	-0.632	0.077	-1.0166	0.0984681205956	None	1.0	0.435	0.0551355673512	0.239	0.320728957653	-2.56	0.122	0.401	0.174	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07297E-04	0	None	N	None
8754	19	Q/H	rs764746720	0.6505	gnomAD-4.0.0	29	None	0.1363	0.1517	15.37	N	-0.231	1.03	0.010526	-0.632	0.077	-1.0166	0.0984681205956	None	1.0	0.435	0.0551355673512	0.239	0.320728957653	-2.56	0.122	0.401	0.174	None	None	5.57899E-06	0	0	0	0	None	0	0	5.57899E-06	0	9.88859E-05	0	None	N	None
8755	20	L/R	None	0.2354	gnomAD-4.0.0	30	None	0.8308	0.8966	24.6	D	None	-0.94	0.081426	-2.077	0.7159	0.7257	0.529006886545	None	1.0	0.785	0.89627696007	0.99	0.59651863575	-4.11	0.761	0.819	0.003	None	None	1.59232E-06	0	0	0	0	None	0	0	1.59232E-06	2.85969E-06	0	0	None	I	None
8756	21	Q/H	rs776025006	0.4193	gnomAD-2.1.1	31	None	0.1926	0.2456	19.36	N	-0.967	-0.31	0.016524	-0.783	0.3783	-0.252	0.362009664807	None	1.0	0.392	0.346315397577	0.993	0.500282049179	-2.81	0.304	0.529	0.221	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
8756	21	Q/H	rs776025006	0.4193	gnomAD-4.0.0	31	None	0.1926	0.2456	19.36	N	-0.967	-0.31	0.016524	-0.783	0.3783	-0.252	0.362009664807	None	1.0	0.392	0.346315397577	0.993	0.500282049179	-2.81	0.304	0.529	0.221	None	None	1.5923E-06	0	0	0	0	None	0	0	1.5923E-06	0	1.43377E-05	0	None	N	None
8756	21	Q/R	rs761090454	0.4193	gnomAD-2.1.1	31	None	0.0928	0.1123	22.2	N	-0.06	-0.26	0.022522	-0.15	0.32	-0.3892	0.284355723822	None	1.0	0.438	0.225215365344	0.901	0.498498380184	-1.82	0.199	0.506	0.218	None	None	4.03E-06	0	2.91E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
8757	22	T/A	None	0.0923	gnomAD-4.0.0	33	None	0.0496	0.0513	13.3	N	None	1.14	0.026849	-1.208	0.0251	-0.9633	0.0819550916224	None	1.0	0.519	0.0138822411134	None	0.347060531378	-1.54	0.116	0.3	0.511	None	None	1.20033E-06	0	0	0	0	None	0	0	1.20033E-06	1.31251E-06	0	0	None	N	None
8757	22	T/I	rs1357129552	0.0923	gnomAD-4.0.0	33	None	0.2624	0.3979	21.2	N	None	1.1	0.020006	0.02	0.1066	-1.0281	0.110045376786	None	1.0	0.552	0.171388866994	0.117	0.420869827271	-2.7	0.266	0.679	0.146	None	None	6.84407E-07	0	0	0	0	None	0	0	6.84407E-07	8.99628E-07	0	0	None	N	None
8757	22	T/N	None	0.0923	gnomAD-4.0.0	33	None	0.2681	0.4035	20.7	N	None	1.0	0.016419	-1.31	0.1162	-0.9939	0.148983051585	None	1.0	0.649	0.167679373172	0.211	0.386585593224	-2.77	0.263	0.683	0.042	None	None	6.84407E-07	0	0	0	0	None	0	0	6.84407E-07	0	1.15988E-05	0	None	N	None
8757	22	T/S	None	0.0923	gnomAD-4.0.0	33	None	0.1141	0.1428	20.4	N	None	1.01	0.01567	-1.5	0.077	-1.0357	0.0864751593092	None	1.0	0.536	0.0716867268079	0.027	0.349204748869	-1.62	0.08	0.517	0.125	None	None	6.84407E-07	0	0	0	0	None	0	0	6.84407E-07	8.99628E-07	0	0	None	N	None
8759	24	I/M	None	0.0709	gnomAD-4.0.0	35	None	0.1074	0.1346	15.03	N	None	-0.51	0.049105	-1.042	0.2761	-0.702	0.11397634511	None	0.999994	0.587	0.184867976434	0.019	0.2972189188	-1.71	0.212	0.661	0.01	None	None	1.59203E-06	0	0	0	0	None	0	0	1.59203E-06	2.85933E-06	0	0	None	N	None
8759	24	I/T	rs199918663	0.0709	gnomAD-2.1.1	35	None	0.129	0.209	None	D	-2.897	None	None	-2.837	None	None	None	None	None	None	None	None	None	None	0.345	0.424	None	None	None	2.86E-05	0	0	0	2.56437E-04	None	6.54E-05	None	2.86E-05	0	7.83E-06	0	None	N	None
8759	24	I/T	rs199918663	0.0709	gnomAD-3.1.2	35	None	0.129	0.209	None	D	-2.897	None	None	-2.837	None	None	None	None	None	None	None	None	None	None	0.345	0.424	None	None	None	1.31E-05	0	0	0	3.85951E-04	None	0	0	1.31E-05	0	0	0	None	N	None
8759	24	I/T	rs199918663	0.0709	gnomAD-4.0.0	35	None	0.129	0.209	None	D	-2.897	None	None	-2.837	None	None	None	None	None	None	None	None	None	None	0.345	0.424	None	None	None	2.29343E-05	0	0	0	6.46312E-04	None	0	0	2.29343E-05	1.69548E-06	5.49113E-05	1.60154E-05	None	N	None
8759	24	I/V	rs1317485542	0.0709	gnomAD-2.1.1	35	None	0.0534	0.0549	12.11	N	-1.533	0.17	0.015186	-1.534	0.0664	-1.0709	0.0703051542146	None	0.808549	0.485	0.154104182512	None	0.278828144073	-0.29	0.079	0.199	1.0	None	None	1.43E-05	0	2.84E-05	0	0	None	0	None	1.43E-05	8.02E-05	0	1.40885E-04	None	N	None
8759	24	I/V	rs1317485542	0.0709	gnomAD-3.1.2	35	None	0.0534	0.0549	12.11	N	-1.533	0.17	0.015186	-1.534	0.0664	-1.0709	0.0703051542146	None	0.808549	0.485	0.154104182512	None	0.278828144073	-0.29	0.079	0.199	1.0	None	None	1.31E-05	0	6.55E-05	0	0	None	9.41E-05	0	1.31E-05	0	0	0	None	N	None
8759	24	I/V	rs1317485542	0.0709	gnomAD-4.0.0	35	None	0.0534	0.0549	12.11	N	-1.533	0.17	0.015186	-1.534	0.0664	-1.0709	0.0703051542146	None	0.808549	0.485	0.154104182512	None	0.278828144073	-0.29	0.079	0.199	1.0	None	None	8.97144E-06	0	1.6956E-05	0	0	None	7.85275E-05	0	8.97144E-06	0	0	2.84592E-05	None	N	None
8760	25	E/K	rs2077161238	0.3516	gnomAD-4.0.0	38	None	0.1134	0.1563	20.3	N	None	-0.28	0.033148	0.213	0.1919	-0.8485	0.0951435873664	None	1.0	0.609	0.229924730088	0.001	0.385894358158	-1.82	0.182	0.108	0.337	None	None	1.77937E-05	0	0	0	0	None	0	0	1.77937E-05	2.33896E-05	0	0	None	N	None
8761	26	G/S	rs369385294	0.3471	gnomAD-2.1.1	40	None	0.3171	0.5774	None	D	-0.776	None	None	-0.796	None	None	None	None	None	None	None	1.0	None	None	0.667	0.842	None	None	None	5.37E-05	4.14E-05	0	0	0	None	0	None	5.37E-05	0	1.09714E-04	0	None	N	None
8761	26	G/S	rs369385294	0.3471	gnomAD-3.1.2	40	None	0.3171	0.5774	None	D	-0.776	None	None	-0.796	None	None	None	None	None	None	None	1.0	None	None	0.667	0.842	None	None	None	5.26E-05	7.24E-05	0	0	0	None	0	0	5.26E-05	7.35E-05	0	0	None	N	None
8761	26	G/S	rs369385294	0.3471	gnomAD-4.0.0	40	None	0.3171	0.5774	None	D	-0.776	None	None	-0.796	None	None	None	None	None	None	None	1.0	None	None	0.667	0.842	None	None	None	1.41941E-04	8.01325E-05	0	0	0	None	0	0	1.41941E-04	1.86499E-04	0	4.80446E-05	None	N	None
8762	27	A/T	rs1336984327	0.5721	gnomAD-2.1.1	41	None	0.0659	0.0681	20.7	N	-0.468	-0.21	0.018782	-0.707	0.1054	-1.0462	0.0809002040292	None	1.0	0.404	0.170165803431	0.001	0.319430112839	-1.26	0.041	0.145	0.64	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	I	None
8762	27	A/T	rs1336984327	0.5721	gnomAD-3.1.2	41	None	0.0659	0.0681	20.7	N	-0.468	-0.21	0.018782	-0.707	0.1054	-1.0462	0.0809002040292	None	1.0	0.404	0.170165803431	0.001	0.319430112839	-1.26	0.041	0.145	0.64	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	I	None
8762	27	A/T	rs1336984327	0.5721	gnomAD-4.0.0	41	None	0.0659	0.0681	20.7	N	-0.468	-0.21	0.018782	-0.707	0.1054	-1.0462	0.0809002040292	None	1.0	0.404	0.170165803431	0.001	0.319430112839	-1.26	0.041	0.145	0.64	None	None	9.29769E-06	0	0	6.75813E-05	0	None	0	0	9.29769E-06	1.01726E-05	0	1.60159E-05	None	I	None
8762	27	A/V	None	0.5721	gnomAD-4.0.0	41	None	0.08	0.0868	22.9	N	None	-0.22	0.046093	-0.364	0.1995	-0.8192	0.0906296443437	None	0.799215	0.426	0.41921206133	0.148	0.339500665665	-1.72	0.289	0.311	0.275	None	None	1.59196E-06	0	0	0	0	None	0	0	1.59196E-06	2.85922E-06	0	0	None	I	None
8763	28	E/A	rs1453342840	0.7787	gnomAD-2.1.1	42	None	0.0931	0.0983	23.2	N	0.161	-0.29	0.042248	-0.269	0.1992	-0.6845	0.152711051343	None	1.0	0.556	0.365120060079	0.567	0.429534524679	-3.29	0.254	0.478	0.576	None	None	6.37E-05	2.29621E-04	0	0	0	None	0	None	6.37E-05	0	0	0	None	I	None
8763	28	E/A	rs1453342840	0.7787	gnomAD-3.1.2	42	None	0.0931	0.0983	23.2	N	0.161	-0.29	0.042248	-0.269	0.1992	-0.6845	0.152711051343	None	1.0	0.556	0.365120060079	0.567	0.429534524679	-3.29	0.254	0.478	0.576	None	None	1.97E-05	7.24E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	I	None
8763	28	E/A	rs1453342840	0.7787	gnomAD-4.0.0	42	None	0.0931	0.0983	23.2	N	0.161	-0.29	0.042248	-0.269	0.1992	-0.6845	0.152711051343	None	1.0	0.556	0.365120060079	0.567	0.429534524679	-3.29	0.254	0.478	0.576	None	None	1.97174E-05	7.23903E-05	0	0	0	None	0	0	1.97174E-05	0	0	0	None	I	None
8764	29	P/S	None	0.6546	gnomAD-4.0.0	43	None	0.2855	0.3423	27.4	N	None	-0.22	0.03769	-0.43	0.5385	0.0768	0.466031226403	None	0.999489	0.541	0.512825096792	1.0	0.520405113697	-4.82	0.483	0.694	0.147	None	None	2.7373E-06	0	0	0	0	None	0	0	2.7373E-06	3.59826E-06	0	0	None	I	None
8764	29	P/T	None	0.6546	gnomAD-4.0.0	43	None	0.2244	0.2785	26.9	N	None	-0.18	0.036552	-0.467	0.481	-0.0665	0.48919594472	None	0.999487	0.532	0.54173910141	1.0	0.550142884254	-4.99	0.469	0.686	0.114	None	None	6.84326E-07	0	0	0	0	None	0	0	6.84326E-07	0	0	1.65706E-05	None	I	None
8765	30	I/T	rs768619883	0.1538	gnomAD-2.1.1	44	None	0.5816	0.7297	25.2	N	-2.622	-0.26	0.038058	-2.537	0.4537	-0.0622	0.463207306321	None	0.866931	0.509	0.776600623924	0.976	0.583519101143	-2.9	0.42	0.615	0.039	None	None	2.02E-05	6.46E-05	8.71E-05	0	5.57E-05	None	0	None	2.02E-05	0	0	0	None	N	None
8765	30	I/T	rs768619883	0.1538	gnomAD-3.1.2	44	None	0.5816	0.7297	25.2	N	-2.622	-0.26	0.038058	-2.537	0.4537	-0.0622	0.463207306321	None	0.866931	0.509	0.776600623924	0.976	0.583519101143	-2.9	0.42	0.615	0.039	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
8765	30	I/T	rs768619883	0.1538	gnomAD-4.0.0	44	None	0.5816	0.7297	25.2	N	-2.622	-0.26	0.038058	-2.537	0.4537	-0.0622	0.463207306321	None	0.866931	0.509	0.776600623924	0.976	0.583519101143	-2.9	0.42	0.615	0.039	None	None	1.28144E-05	3.38409E-05	5.08613E-05	0	2.42518E-05	None	0	0	1.28144E-05	7.18061E-06	0	2.84527E-05	None	N	None
8765	30	I/V	rs776531934	0.1538	gnomAD-2.1.1	44	None	0.0801	0.0898	21.4	D	-1.518	-0.22	0.022965	-1.483	0.2909	-0.5581	0.112203004936	None	1.0	0.45	0.581442141994	0.192	0.406627178192	-0.57	0.124	0.441	0.792	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
8765	30	I/V	rs776531934	0.1538	gnomAD-4.0.0	44	None	0.0801	0.0898	21.4	D	-1.518	-0.22	0.022965	-1.483	0.2909	-0.5581	0.112203004936	None	1.0	0.45	0.581442141994	0.192	0.406627178192	-0.57	0.124	0.441	0.792	None	None	1.59174E-06	0	0	0	0	None	0	0	1.59174E-06	2.85901E-06	0	0	None	N	None
8766	31	S/L	rs1368458893	0.4642	gnomAD-2.1.1	45	None	0.1051	0.1263	24.4	N	0.385	-0.4	0.038549	0.218	0.3203	-0.5317	0.0778072030269	None	1.0	0.488	0.593771126905	0.044	0.540663361549	-3.52	0.313	0.339	0.07	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
8766	31	S/L	rs1368458893	0.4642	gnomAD-4.0.0	45	None	0.1051	0.1263	24.4	N	0.385	-0.4	0.038549	0.218	0.3203	-0.5317	0.0778072030269	None	1.0	0.488	0.593771126905	0.044	0.540663361549	-3.52	0.313	0.339	0.07	None	None	1.5918E-06	0	2.28739E-05	0	0	None	0	0	1.5918E-06	0	0	0	None	N	None
8769	34	W/G	rs779847107	0.1228	gnomAD-4.0.0	48	None	0.9255	0.9572	26.7	D	-2.495	-3.96	0.555178	-2.984	0.9667	1.0871	0.615612516959	None	0.99791	0.884	0.929467472191	1.0	0.661473870277	-8.53	0.916	0.817	0.002	None	None	4.7901E-06	0	0	0	0	None	0	0	4.7901E-06	6.29681E-06	0	0	None	N	None
8770	35	F/S	None	0.1393	gnomAD-4.0.0	49	None	0.2968	0.4856	24.1	N	None	0.87	0.027687	-2.508	0.1098	-0.9154	0.216843438073	None	1.0	0.676	0.575814496085	0.844	0.457750618458	-3.89	0.346	0.53	0.018	None	None	1.59167E-06	0	0	0	0	None	0	0	1.59167E-06	2.85892E-06	0	0	None	N	None
8770	35	F/V	rs2077156183	0.1393	gnomAD-3.1.2	49	None	0.1256	0.1934	23.9	N	None	0.88	0.014047	-1.935	0.0978	-0.9988	0.110997740317	None	1.0	0.642	0.447901950027	0.002	0.425163626671	-2.88	0.203	0.251	0.196	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07211E-04	0	None	N	None
8770	35	F/V	rs2077156183	0.1393	gnomAD-4.0.0	49	None	0.1256	0.1934	23.9	N	None	0.88	0.014047	-1.935	0.0978	-0.9988	0.110997740317	None	1.0	0.642	0.447901950027	0.002	0.425163626671	-2.88	0.203	0.251	0.196	None	None	6.57324E-06	0	0	0	0	None	0	0	6.57324E-06	0	2.07211E-04	0	None	N	None
8771	36	K/R	None	0.2510	gnomAD-4.0.0	50	None	0.0834	0.0885	26.2	N	None	0.76	0.042809	-0.653	0.2124	-0.6511	0.242925473067	None	1.0	0.741	0.277317399466	0.93	0.426455676556	-1.72	0.337	0.491	0.209	None	None	1.59165E-06	0	0	0	0	None	0	0	1.59165E-06	2.85887E-06	0	0	None	N	None
8772	37	D/V	None	0.3957	gnomAD-4.0.0	51	None	0.3891	0.5257	24.8	N	None	0.68	0.041404	-0.051	0.3319	-0.2327	0.344494035736	None	0.999988	0.728	0.42828666871	0.682	0.492381125689	-5.71	0.404	0.713	0.003	None	None	1.20033E-06	6.33473E-05	0	0	0	None	0	0	1.20033E-06	0	0	0	None	N	None
8772	37	D/Y	None	0.3957	gnomAD-4.0.0	51	None	0.3507	0.4649	25.1	N	None	0.68	0.029985	0.074	0.3978	-0.0693	0.44339968825	None	0.998795	0.698	0.617940983249	0.997	0.535695433617	-5.73	0.447	0.707	0.003	None	None	1.20033E-06	0	0	0	0	None	0	0	1.20033E-06	1.31251E-06	0	0	None	N	None
8773	38	K/N	None	0.7553	gnomAD-4.0.0	52	None	0.3031	0.4061	17.62	N	None	1.08	0.023896	0.313	0.0586	-1.0905	0.101494023942	None	1.0	0.558	0.0401082797425	0.007	0.4972884655	-3.1	0.031	0.277	0.8	None	None	3.42147E-06	0	0	0	0	None	0	0	3.42147E-06	4.49769E-06	0	0	None	N	None
8774	39	G/E	None	0.2739	gnomAD-4.0.0	55	None	0.1261	0.1715	23.1	N	None	-0.39	0.034994	-0.443	0.1871	-0.8435	0.111478091002	None	0.534833	0.743	0.32053947749	0.007	0.463279724121	-3.71	0.384	0.293	0.365	None	None	6.84279E-07	0	0	0	0	None	0	0	6.84279E-07	0	0	1.65684E-05	None	N	None
8775	40	E/A	rs758590305	0.4034	gnomAD-2.1.1	56	None	0.1832	0.2354	26.7	N	-0.516	-0.3	0.049553	-0.635	0.3558	-0.2501	0.25013123898	None	0.845788	0.52	0.413113201963	0.884	0.373491823673	-3.39	0.377	0.521	0.014	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.94E-06	0	None	N	None
8775	40	E/A	rs758590305	0.4034	gnomAD-4.0.0	56	None	0.1832	0.2354	26.7	N	-0.516	-0.3	0.049553	-0.635	0.3558	-0.2501	0.25013123898	None	0.845788	0.52	0.413113201963	0.884	0.373491823673	-3.39	0.377	0.521	0.014	None	None	1.59164E-06	0	0	0	0	None	0	0	1.59164E-06	2.85884E-06	0	0	None	N	None
8775	40	E/D	None	0.4034	gnomAD-4.0.0	56	None	0.1024	0.1001	21.3	N	None	-0.34	0.023485	-0.594	0.2621	-0.6863	0.106156357008	None	1.0	0.432	0.282575091529	0.288	0.371044874191	-1.86	0.166	0.484	0.015	None	None	1.20033E-06	0	0	0	0	None	0	0	1.20033E-06	0	6.07533E-05	0	None	N	None
8776	41	I/L	rs746071731	0.1580	gnomAD-2.1.1	57	None	0.097	0.1341	17.72	N	-0.022	-0.18	0.027847	-0.54	0.1607	-1.0511	0.0841806381515	None	1.0	0.415	0.0666544352282	None	0.282285034657	-1.13	0.176	0.337	0.262	None	None	4.03E-06	0	0	0	5.57E-05	None	0	None	4.03E-06	0	0	0	None	N	None
8776	41	I/L	rs746071731	0.1580	gnomAD-4.0.0	57	None	0.097	0.1341	17.72	N	-0.022	-0.18	0.027847	-0.54	0.1607	-1.0511	0.0841806381515	None	1.0	0.415	0.0666544352282	None	0.282285034657	-1.13	0.176	0.337	0.262	None	None	1.59158E-06	0	0	0	2.77285E-05	None	0	0	1.59158E-06	0	0	0	None	N	None
8776	41	I/M	None	0.1580	gnomAD-4.0.0	57	None	0.0726	0.0995	16.12	N	None	-0.21	0.031592	-0.559	0.243	-0.8784	0.0893733305744	None	1.0	0.431	0.0884992946249	0.005	0.278680294752	-1.72	0.216	0.376	0.067	None	None	6.84287E-07	0	0	0	0	None	0	0	6.84287E-07	8.99536E-07	0	0	None	N	None
8776	41	I/V	rs746071731	0.1580	gnomAD-2.1.1	57	None	0.0647	0.0716	16.32	N	-0.562	-0.18	0.028343	-0.758	0.1481	-1.0747	0.0704899027279	None	1.0	0.403	0.119812018005	None	0.259340167046	-0.56	0.144	0.192	0.474	None	None	8.07E-06	0	5.8E-05	0	0	None	0	None	8.07E-06	0	0	0	None	N	None
8776	41	I/V	rs746071731	0.1580	gnomAD-3.1.2	57	None	0.0647	0.0716	16.32	N	-0.562	-0.18	0.028343	-0.758	0.1481	-1.0747	0.0704899027279	None	1.0	0.403	0.119812018005	None	0.259340167046	-0.56	0.144	0.192	0.474	None	None	6.57E-06	0	6.55E-05	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
8776	41	I/V	rs746071731	0.1580	gnomAD-4.0.0	57	None	0.0647	0.0716	16.32	N	-0.562	-0.18	0.028343	-0.758	0.1481	-1.0747	0.0704899027279	None	1.0	0.403	0.119812018005	None	0.259340167046	-0.56	0.144	0.192	0.474	None	None	5.1251E-06	0	6.78104E-05	0	0	None	0	0	5.1251E-06	0	0	0	None	N	None
8777	42	V/D	None	0.4917	gnomAD-4.0.0	58	None	0.7039	0.7939	26.0	N	None	-0.42	0.067524	-2.525	0.3046	-0.333	0.257780808339	None	0.999956	0.695	0.846757116288	0.908	0.474733412266	-4.26	0.519	0.444	0.001	None	None	1.59157E-06	0	0	0	0	None	0	0	1.59157E-06	2.85873E-06	0	0	None	N	None
8777	42	V/F	rs376823283	0.4917	gnomAD-2.1.1	58	None	0.192	0.2342	20.7	N	-0.593	-0.37	0.053083	-1.093	0.2517	-0.5456	0.192818670228	None	0.508704	0.602	0.787097682969	0.754	0.443462967873	-2.76	0.38	0.359	0.01	None	None	8.07E-06	0	5.8E-05	0	0	None	0	None	8.07E-06	0	0	0	None	N	None
8777	42	V/F	rs376823283	0.4917	gnomAD-4.0.0	58	None	0.192	0.2342	20.7	N	-0.593	-0.37	0.053083	-1.093	0.2517	-0.5456	0.192818670228	None	0.508704	0.602	0.787097682969	0.754	0.443462967873	-2.76	0.38	0.359	0.01	None	None	2.73711E-06	0	4.47387E-05	0	0	None	0	0	2.73711E-06	1.79906E-06	0	0	None	N	None
8777	42	V/I	None	0.4917	gnomAD-2.1.1	58	None	0.0735	0.0735	None	N	-0.026	None	None	-0.273	None	None	None	None	None	None	None	None	None	None	0.064	0.145	None	None	None	6.8E-05	4.14E-05	2.83E-05	0	0	None	0	None	6.8E-05	0	1.33578E-04	0	None	N	None
8777	42	V/I	None	0.4917	gnomAD-3.1.2	58	None	0.0735	0.0735	None	N	-0.026	None	None	-0.273	None	None	None	None	None	None	None	None	None	None	0.064	0.145	None	None	None	1.44585E-04	9.65E-05	6.55E-05	0	0	None	0	0	1.44585E-04	2.49941E-04	0	0	None	N	None
8777	42	V/I	None	0.4917	gnomAD-4.0.0	58	None	0.0735	0.0735	None	N	-0.026	None	None	-0.273	None	None	None	None	None	None	None	None	None	None	0.064	0.145	None	None	None	1.19612E-04	6.67485E-05	3.33467E-05	0	0	None	1.56284E-05	0	1.19612E-04	1.53428E-04	0	6.40574E-05	None	N	None
8777	42	V/L	rs376823283	0.4917	gnomAD-3.1.2	58	None	0.1284	0.1474	19.25	N	None	0.05	0.014781	-0.273	0.1289	-0.9577	0.0819424430668	None	1.0	0.484	0.312306559268	None	0.452519983053	-1.07	0.122	0.127	0.352	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	0	4.78469E-04	None	N	None
8777	42	V/L	rs376823283	0.4917	gnomAD-4.0.0	58	None	0.1284	0.1474	19.25	N	None	0.05	0.014781	-0.273	0.1289	-0.9577	0.0819424430668	None	1.0	0.484	0.312306559268	None	0.452519983053	-1.07	0.122	0.127	0.352	None	None	1.85925E-06	0	0	0	0	None	0	0	1.85925E-06	1.69533E-06	0	1.60143E-05	None	N	None
8778	43	R/K	rs1486145907	0.8228	gnomAD-3.1.2	59	None	0.1276	0.1547	23.1	N	None	-0.18	0.014093	-0.225	0.3191	-0.4227	0.439910430065	None	0.570045	0.535	0.315609569513	0.972	0.58319401741	-1.85	0.297	0.56	0.279	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	1.47E-05	2.07039E-04	0	None	N	None
8778	43	R/K	rs1486145907	0.8228	gnomAD-4.0.0	59	None	0.1276	0.1547	23.1	N	None	-0.18	0.014093	-0.225	0.3191	-0.4227	0.439910430065	None	0.570045	0.535	0.315609569513	0.972	0.58319401741	-1.85	0.297	0.56	0.279	None	None	8.05664E-06	0	0	0	0	None	0	0	8.05664E-06	9.32417E-06	2.19582E-05	0	None	N	None
8778	43	R/S	rs754011566	0.8228	gnomAD-2.1.1	59	None	0.4619	0.6078	24.6	D	-0.04	-0.22	0.046549	-0.4	0.3957	-0.3662	0.487728487079	None	1.0	0.547	0.380730819819	1.0	0.539027094841	-3.52	0.388	0.651	0.066	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.94E-06	0	None	N	None
8778	43	R/T	rs1486145907	0.8228	gnomAD-2.1.1	59	None	0.24	0.3346	23.2	N	0.116	-0.25	0.026338	-0.23	0.4201	-0.2274	0.556881023561	None	0.896333	0.546	0.646531519106	1.0	0.572387814522	-3.76	0.39	0.645	0.093	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
8778	43	R/T	rs1486145907	0.8228	gnomAD-4.0.0	59	None	0.24	0.3346	23.2	N	0.116	-0.25	0.026338	-0.23	0.4201	-0.2274	0.556881023561	None	0.896333	0.546	0.646531519106	1.0	0.572387814522	-3.76	0.39	0.645	0.093	None	None	6.84268E-07	0	0	0	0	None	0	0	6.84268E-07	8.9952E-07	0	0	None	N	None
8780	45	S/G	None	0.2531	gnomAD-4.0.0	73	None	0.096	0.1035	20.7	N	None	0.96	0.016111	-0.419	0.0897	-1.0579	0.0766810984944	None	1.0	0.524	0.0762999501168	0.001	0.438948214054	-1.75	0.075	0.143	0.114	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
8780	45	S/N	rs764652580	0.2531	gnomAD-2.1.1	73	None	0.1481	0.1695	22.8	N	-0.256	0.86	0.075391	-0.259	0.1885	-0.8268	0.0802319615533	None	0.547907	0.516	0.0920862733494	0.083	0.500794231892	-1.79	0.262	0.435	0.037	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.94E-06	0	None	N	None
8780	45	S/N	rs764652580	0.2531	gnomAD-4.0.0	73	None	0.1481	0.1695	22.8	N	-0.256	0.86	0.075391	-0.259	0.1885	-0.8268	0.0802319615533	None	0.547907	0.516	0.0920862733494	0.083	0.500794231892	-1.79	0.262	0.435	0.037	None	None	1.77904E-05	0	0	0	0	None	0	0	1.77904E-05	2.33872E-05	0	0	None	N	None
8780	45	S/R	rs756708089	0.2531	gnomAD-2.1.1	73	None	0.6979	0.753	25.6	N	-0.324	0.78	0.045163	-0.308	0.2019	-0.5258	0.199482030292	None	0.953319	0.533	0.306377322295	0.953	0.507127285004	-3.15	0.272	0.339	0.012	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.94E-06	0	None	N	None
8780	45	S/R	rs756708089	0.2531	gnomAD-4.0.0	73	None	0.6979	0.753	25.6	N	-0.324	0.78	0.045163	-0.308	0.2019	-0.5258	0.199482030292	None	0.953319	0.533	0.306377322295	0.953	0.507127285004	-3.15	0.272	0.339	0.012	None	None	1.59146E-06	0	0	0	0	None	0	0	1.59146E-06	2.85863E-06	0	0	None	N	None
8781	46	D/A	rs2077152071	0.6046	gnomAD-3.1.2	111	None	0.1272	0.1398	25.1	N	None	0.95	0.025219	0.09	0.1358	-0.9105	0.138174416641	None	0.686692	0.581	0.250039746154	0.328	0.494914144278	-4.83	0.238	0.369	0.637	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	0	4.78011E-04	None	N	None
8781	46	D/A	rs2077152071	0.6046	gnomAD-4.0.0	111	None	0.1272	0.1398	25.1	N	None	0.95	0.025219	0.09	0.1358	-0.9105	0.138174416641	None	0.686692	0.581	0.250039746154	0.328	0.494914144278	-4.83	0.238	0.369	0.637	None	None	6.57168E-06	0	0	0	0	None	0	0	6.57168E-06	0	0	4.78011E-04	None	N	None
8781	46	D/N	None	0.6046	gnomAD-4.0.0	111	None	0.083	0.0927	23.9	N	None	0.95	0.046842	0.366	0.1799	-0.7704	0.166489251295	None	0.826521	0.544	0.143124449307	0.604	0.542073249817	-3.02	0.328	0.343	0.359	None	None	6.00161E-06	0	0	0	0	None	0	0	6.00161E-06	6.56251E-06	0	0	None	N	None
8782	47	N/S	rs727504895	0.3130	gnomAD-4.0.0	115	None	0.0864	0.0886	22.6	N	None	1.01	0.020849	-0.567	0.0978	-1.0034	0.0677024119643	None	1.0	0.494	0.0846915920261	0.03	0.510577976704	-2.73	0.094	0.115	0.278	None	None	1.36848E-06	0	0	0	2.51915E-05	None	0	0	1.36848E-06	8.99501E-07	0	0	None	N	None
8782	47	N/Y	rs1017848590	0.3130	gnomAD-3.1.2	115	None	0.2031	0.2188	23.9	N	None	0.97	0.066386	-0.561	0.2505	-0.5739	0.496345723792	None	1.0	0.547	0.39724302092	1.0	0.586527168751	-4.81	0.35	0.52	0.092	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	2.94E-05	0	0	None	N	None
8782	47	N/Y	rs1017848590	0.3130	gnomAD-4.0.0	115	None	0.2031	0.2188	23.9	N	None	0.97	0.066386	-0.561	0.2505	-0.5739	0.496345723792	None	1.0	0.547	0.39724302092	1.0	0.586527168751	-4.81	0.35	0.52	0.092	None	None	9.29567E-06	0	0	0	0	None	0	0	9.29567E-06	1.1867E-05	0	1.60118E-05	None	N	None
8783	48	I/K	rs1226202295	0.0825	gnomAD-3.1.2	121	None	0.3093	0.3589	22.9	N	None	-0.36	0.054729	-1.525	0.3385	-0.4858	0.165813641019	None	0.903144	0.688	0.774775221225	0.001	0.351404696703	-2.67	0.395	0.623	0.281	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
8783	48	I/K	rs1226202295	0.0825	gnomAD-4.0.0	121	None	0.3093	0.3589	22.9	N	None	-0.36	0.054729	-1.525	0.3385	-0.4858	0.165813641019	None	0.903144	0.688	0.774775221225	0.001	0.351404696703	-2.67	0.395	0.623	0.281	None	None	6.57082E-06	2.41231E-05	0	0	0	None	0	0	6.57082E-06	0	0	0	None	N	None
8783	48	I/L	None	0.0825	gnomAD-4.0.0	121	None	0.0971	0.1035	22.2	D	None	-0.22	0.024131	-0.848	0.2023	-0.8462	0.0830569285264	None	1.0	0.514	0.301789629655	None	0.317061722279	-0.76	0.075	0.165	0.637	None	None	6.84237E-07	0	0	0	0	None	0	0	6.84237E-07	8.99501E-07	0	0	None	N	None
8783	48	I/M	rs767996372	0.0825	gnomAD-2.1.1	121	None	0.0964	0.1042	21.8	N	-0.883	-0.33	0.025525	-0.8	0.3202	-0.5651	0.136199351718	None	1.0	0.551	0.429552544315	0.039	0.306940466166	-1.13	0.23	0.612	0.214	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.94E-06	0	None	N	None
8783	48	I/M	rs767996372	0.0825	gnomAD-4.0.0	121	None	0.0964	0.1042	21.8	N	-0.883	-0.33	0.025525	-0.8	0.3202	-0.5651	0.136199351718	None	1.0	0.551	0.429552544315	0.039	0.306940466166	-1.13	0.23	0.612	0.214	None	None	6.15819E-06	0	0	0	0	None	0	0	6.15819E-06	7.19602E-06	0	1.65662E-05	None	N	None
8783	48	I/T	rs1226202295	0.0825	gnomAD-2.1.1	121	None	0.1427	0.1478	22.9	N	-2.256	-0.32	0.037122	-2.104	0.3236	-0.5278	0.133976502449	None	1.0	0.64	0.646043907412	0.014	0.383164525032	-1.94	0.252	0.586	0.384	None	None	4.03E-06	0	0	0	5.57E-05	None	0	None	4.03E-06	0	0	0	None	N	None
8783	48	I/T	rs1226202295	0.0825	gnomAD-4.0.0	121	None	0.1427	0.1478	22.9	N	-2.256	-0.32	0.037122	-2.104	0.3236	-0.5278	0.133976502449	None	1.0	0.64	0.646043907412	0.014	0.383164525032	-1.94	0.252	0.586	0.384	None	None	1.36848E-06	0	0	0	2.51915E-05	None	0	0	1.36848E-06	8.99497E-07	0	0	None	N	None
8783	48	I/V	rs2077150875	0.0825	gnomAD-4.0.0	121	None	0.073	0.0737	21.8	N	None	-0.18	0.006516	-1.274	0.1356	-0.9854	0.0704899027279	None	1.0	0.539	0.36076525451	None	0.289316266775	-0.43	0.118	0.187	0.527	None	None	4.78966E-06	0	0	0	0	None	0	0	4.78966E-06	3.598E-06	2.31873E-05	1.65673E-05	None	N	None
8784	49	W/R	rs375067750	0.7364	gnomAD-2.1.1	122	None	0.1403	0.1619	22.9	N	-0.1	-0.08	0.018543	0.034	0.0937	-0.9851	0.151848470416	None	1.0	0.499	0.427254322456	0.005	0.620418548584	-5.98	0.243	0.323	0.671	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	1.79E-05	1.66113E-04	None	N	None
8784	49	W/R	rs375067750	0.7364	gnomAD-3.1.2	122	None	0.1403	0.1619	22.9	N	-0.1	-0.08	0.018543	0.034	0.0937	-0.9851	0.151848470416	None	1.0	0.499	0.427254322456	0.005	0.620418548584	-5.98	0.243	0.323	0.671	None	None	1.97E-05	0	0	0	0	None	0	0	1.97E-05	4.41E-05	0	0	None	N	None
8784	49	W/R	rs375067750	0.7364	gnomAD-4.0.0	122	None	0.1403	0.1619	22.9	N	-0.1	-0.08	0.018543	0.034	0.0937	-0.9851	0.151848470416	None	1.0	0.499	0.427254322456	0.005	0.620418548584	-5.98	0.243	0.323	0.671	None	None	1.30137E-05	0	0	0	0	None	0	0	1.30137E-05	1.78001E-05	0	0	None	N	None
8785	50	I/F	rs2077149198	0.2581	gnomAD-4.0.0	123	None	0.1331	0.1886	23.0	N	None	-0.38	0.107387	-1.325	0.2904	-0.5368	0.156201119995	None	0.613622	0.54	0.456830177556	0.076	0.417887657881	-2.55	0.354	0.443	0.138	None	None	3.18283E-06	0	2.28697E-05	0	0	None	0	0	3.18283E-06	2.85853E-06	0	0	None	N	None
8786	51	S/A	None	0.3621	gnomAD-4.0.0	125	None	0.0869	0.0989	23.4	N	None	-0.25	0.024767	-0.702	0.3142	-0.4568	0.111660899099	None	1.0	0.471	0.263140351381	0.308	0.42207044363	-1.65	0.172	0.399	0.768	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
8787	52	Y/C	rs1365431842	0.2777	gnomAD-2.1.1	127	None	0.1294	0.1803	28.0	N	-0.867	-0.29	0.043876	-0.891	0.4724	0.0827	0.405544506538	None	1.0	0.668	0.692462537607	0.993	0.51036798954	-5.0	0.537	0.661	0.169	None	None	8.07E-06	0	0	0	1.11346E-04	None	0	None	8.07E-06	0	0	0	None	N	None
8787	52	Y/C	rs1365431842	0.2777	gnomAD-4.0.0	127	None	0.1294	0.1803	28.0	N	-0.867	-0.29	0.043876	-0.891	0.4724	0.0827	0.405544506538	None	1.0	0.668	0.692462537607	0.993	0.51036798954	-5.0	0.537	0.661	0.169	None	None	2.05272E-06	0	0	0	7.55744E-05	None	0	0	2.05272E-06	0	0	0	None	N	None
8787	52	Y/F	None	0.2777	gnomAD-4.0.0	127	None	0.1005	0.1035	23.6	N	None	-0.25	0.013913	-0.726	0.1438	-0.9151	0.076699842996	None	1.0	0.608	0.289847578895	None	0.434009790421	-1.88	0.142	0.281	0.688	None	None	6.8424E-07	0	0	0	0	None	0	0	6.8424E-07	8.99497E-07	0	0	None	N	None
8790	55	N/D	rs772728050	0.5289	gnomAD-2.1.1	134	None	0.1199	0.14	22.4	D	0.276	-0.22	0.041261	0.162	0.2663	-0.5883	0.108926824626	None	1.0	0.607	0.211220785272	0.048	0.574565887451	-2.76	0.173	0.394	0.783	None	None	2.15E-05	0	0	0	3.07377E-04	None	0	None	2.15E-05	0	0	0	None	N	None
8790	55	N/D	rs772728050	0.5289	gnomAD-3.1.2	134	None	0.1199	0.14	22.4	D	0.276	-0.22	0.041261	0.162	0.2663	-0.5883	0.108926824626	None	1.0	0.607	0.211220785272	0.048	0.574565887451	-2.76	0.173	0.394	0.783	None	None	6.57E-06	0	0	0	1.92604E-04	None	0	0	6.57E-06	0	0	0	None	N	None
8790	55	N/D	rs772728050	0.5289	gnomAD-4.0.0	134	None	0.1199	0.14	22.4	D	0.276	-0.22	0.041261	0.162	0.2663	-0.5883	0.108926824626	None	1.0	0.607	0.211220785272	0.048	0.574565887451	-2.76	0.173	0.394	0.783	None	None	2.47876E-06	0	0	0	8.91107E-05	None	0	0	2.47876E-06	0	0	0	None	N	None
8791	56	I/F	None	0.1420	gnomAD-4.0.0	135	None	0.0973	0.1275	22.0	N	None	-0.33	0.033856	-1.421	0.26	-0.7422	0.139205011144	None	0.999995	0.55	0.331365685468	0.02	0.271809279919	-2.42	0.187	0.445	0.141	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
8792	57	A/E	rs761198294	0.0711	gnomAD-2.1.1	136	None	0.8414	0.9269	24.7	N	-2.074	0.92	0.069861	-1.442	0.1978	-0.6061	0.291305071471	None	1.0	0.616	0.323342291347	0.999	0.505671024323	-2.69	0.24	0.798	0.282	None	None	4.03E-06	6.47E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
8792	57	A/E	rs761198294	0.0711	gnomAD-3.1.2	136	None	0.8414	0.9269	24.7	N	-2.074	0.92	0.069861	-1.442	0.1978	-0.6061	0.291305071471	None	1.0	0.616	0.323342291347	0.999	0.505671024323	-2.69	0.24	0.798	0.282	None	None	2.63E-05	7.24E-05	6.55E-05	0	0	None	0	0	2.63E-05	0	0	0	None	N	None
8792	57	A/E	rs761198294	0.0711	gnomAD-4.0.0	136	None	0.8414	0.9269	24.7	N	-2.074	0.92	0.069861	-1.442	0.1978	-0.6061	0.291305071471	None	1.0	0.616	0.323342291347	0.999	0.505671024323	-2.69	0.24	0.798	0.282	None	None	4.33802E-06	6.67557E-05	1.66706E-05	0	0	None	0	0	4.33802E-06	0	0	1.60108E-05	None	N	None
8792	57	A/S	rs764989717	0.0711	gnomAD-2.1.1	136	None	0.1724	0.2143	22.0	N	-1.387	1.06	0.020363	-1.46	0.1474	-0.8841	0.128528489135	None	1.0	0.508	0.148003135375	0.848	0.427320122719	-1.7	0.099	0.717	0.424	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
8792	57	A/S	rs764989717	0.0711	gnomAD-3.1.2	136	None	0.1724	0.2143	22.0	N	-1.387	1.06	0.020363	-1.46	0.1474	-0.8841	0.128528489135	None	1.0	0.508	0.148003135375	0.848	0.427320122719	-1.7	0.099	0.717	0.424	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
8792	57	A/S	rs764989717	0.0711	gnomAD-4.0.0	136	None	0.1724	0.2143	22.0	N	-1.387	1.06	0.020363	-1.46	0.1474	-0.8841	0.128528489135	None	1.0	0.508	0.148003135375	0.848	0.427320122719	-1.7	0.099	0.717	0.424	None	None	2.5623E-06	0	0	0	0	None	0	0	2.5623E-06	4.78631E-06	0	0	None	N	None
8793	58	T/A	rs776154251	0.2091	gnomAD-2.1.1	137	None	0.0765	0.0853	21.3	D	-1.493	-0.46	0.037806	-1.048	0.2197	-0.6914	0.0825183256142	None	1.0	0.545	0.255270683199	0.001	0.406995147467	-2.47	0.241	0.28	0.196	None	None	5.37E-05	0	0	0	0	None	0	None	5.37E-05	5.59642E-04	7.85E-06	0	None	N	None
8793	58	T/A	rs776154251	0.2091	gnomAD-3.1.2	137	None	0.0765	0.0853	21.3	D	-1.493	-0.46	0.037806	-1.048	0.2197	-0.6914	0.0825183256142	None	1.0	0.545	0.255270683199	0.001	0.406995147467	-2.47	0.241	0.28	0.196	None	None	1.97E-05	0	0	0	0	None	1.88324E-04	0	1.97E-05	1.47E-05	0	0	None	N	None
8793	58	T/A	rs776154251	0.2091	gnomAD-4.0.0	137	None	0.0765	0.0853	21.3	D	-1.493	-0.46	0.037806	-1.048	0.2197	-0.6914	0.0825183256142	None	1.0	0.545	0.255270683199	0.001	0.406995147467	-2.47	0.241	0.28	0.196	None	None	1.54926E-05	0	0	0	0	None	2.96856E-04	0	1.54926E-05	5.08581E-06	0	0	None	N	None
8794	59	L/I	None	0.0562	gnomAD-2.1.1	138	None	0.163	0.223	None	D	0.057	None	None	-0.438	None	None	None	None	None	None	None	0.165	None	None	0.258	0.633	None	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
8794	59	L/I	None	0.0562	gnomAD-3.1.2	138	None	0.163	0.223	None	D	0.057	None	None	-0.438	None	None	None	None	None	None	None	0.165	None	None	0.258	0.633	None	None	None	1.97E-05	0	0	0	0	None	0	0	1.97E-05	4.41E-05	0	0	None	N	None
8794	59	L/I	None	0.0562	gnomAD-4.0.0	138	None	0.163	0.223	None	D	0.057	None	None	-0.438	None	None	None	None	None	None	None	0.165	None	None	0.258	0.633	None	None	None	3.09861E-06	0	0	0	0	None	0	0	3.09861E-06	4.23819E-06	0	0	None	N	None
8794	59	L/V	rs372229450	0.0562	gnomAD-2.1.1	138	None	0.1712	0.2125	18.74	D	-0.582	-0.68	0.022286	-0.978	0.3992	-0.4835	0.087857713543	None	1.0	0.847	0.555987101472	0.005	0.428622603416	-2.02	0.289	0.439	0.016	None	None	2.5E-05	0	0	0	3.58607E-04	None	0	None	2.5E-05	0	0	0	None	N	None
8794	59	L/V	rs372229450	0.0562	gnomAD-3.1.2	138	None	0.1712	0.2125	18.74	D	-0.582	-0.68	0.022286	-0.978	0.3992	-0.4835	0.087857713543	None	1.0	0.847	0.555987101472	0.005	0.428622603416	-2.02	0.289	0.439	0.016	None	None	1.97E-05	0	0	0	5.78258E-04	None	0	0	1.97E-05	0	0	0	None	N	None
8794	59	L/V	rs372229450	0.0562	1000 genomes	138	None	0.1712	0.2125	18.74	D	-0.582	-0.68	0.022286	-0.978	0.3992	-0.4835	0.087857713543	None	1.0	0.847	0.555987101472	0.005	0.428622603416	-2.02	0.289	0.439	0.016	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	N	None
8794	59	L/V	rs372229450	0.0562	gnomAD-4.0.0	138	None	0.1712	0.2125	18.74	D	-0.582	-0.68	0.022286	-0.978	0.3992	-0.4835	0.087857713543	None	1.0	0.847	0.555987101472	0.005	0.428622603416	-2.02	0.289	0.439	0.016	None	None	1.79706E-05	0	0	0	6.23969E-04	None	0	0	1.79706E-05	8.47643E-07	0	0	None	N	None
8795	60	Q/E	None	0.5322	gnomAD-4.0.0	139	None	0.0952	0.1007	20.6	N	None	-0.16	0.020002	-1.433	0.2135	-0.7964	0.103848864121	None	1.0	0.537	0.276482976112	0.071	0.313973128796	-1.34	0.121	0.349	0.824	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	0	3.66327E-05	None	N	None
8795	60	Q/R	None	0.5322	gnomAD-4.0.0	139	None	0.0791	0.0863	22.2	N	None	-0.09	0.020639	-0.656	0.2011	-0.8086	0.110821970066	None	1.0	0.504	0.171388866994	0.046	0.319140285254	-1.52	0.123	0.433	0.32	None	None	1.59134E-06	0	0	0	0	None	0	0	1.59134E-06	2.85847E-06	0	0	None	N	None
8796	61	F/C	None	0.1576	gnomAD-4.0.0	140	None	0.2614	0.3395	27.0	N	None	-0.28	0.053691	-2.459	0.454	-0.009	0.412501317473	None	0.600074	0.737	0.71030341735	0.929	0.441127896309	-3.83	0.554	0.787	0.005	None	None	3.42113E-06	0	0	0	0	None	0	0	3.42113E-06	4.49748E-06	0	0	None	N	None
8796	61	F/L	rs1193918191	0.1576	gnomAD-2.1.1	140	None	0.4696	0.4433	22.2	N	-0.784	-0.07	0.019241	-1.723	0.0815	-1.0639	0.0979166354652	None	1.0	0.538	0.213573922156	None	0.442643880844	-2.22	0.135	0.3	0.269	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
8796	61	F/L	rs1193918191	0.1576	gnomAD-4.0.0	140	None	0.4696	0.4433	22.2	N	-0.784	-0.07	0.019241	-1.723	0.0815	-1.0639	0.0979166354652	None	1.0	0.538	0.213573922156	None	0.442643880844	-2.22	0.135	0.3	0.269	None	None	1.59133E-06	0	0	0	0	None	0	0	1.59133E-06	2.8585E-06	0	0	None	N	None
8797	62	S/A	None	0.2623	gnomAD-4.0.0	141	None	0.0686	0.0781	18.02	N	None	-0.3	0.025637	-0.594	0.1449	-0.9083	0.0699420445815	None	1.0	0.485	0.119812018005	None	0.310585081577	-1.39	0.115	0.085	0.793	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
8798	63	R/K	None	0.8256	gnomAD-4.0.0	143	None	0.0684	0.074	19.57	N	None	1.11	0.025443	-0.214	0.0508	-1.0915	0.0842569272004	None	1.0	0.528	0.0846915920261	None	0.291881978512	-0.7	0.052	0.173	1.0	None	None	6.84225E-07	0	0	0	0	None	0	0	6.84225E-07	8.99491E-07	0	0	None	N	None
8798	63	R/T	rs771748059	0.8256	gnomAD-2.1.1	143	None	0.0757	0.0725	19.6	N	0.116	1.0	0.019775	-0.083	0.0724	-1.0613	0.125211133224	None	1.0	0.586	0.136095386433	None	0.276747375727	-2.41	0.093	0.177	0.072	None	None	3.22E-05	0	8.7E-05	0	0	None	0	None	3.22E-05	0	3.57E-05	1.65948E-04	None	N	None
8798	63	R/T	rs771748059	0.8256	gnomAD-3.1.2	143	None	0.0757	0.0725	19.6	N	0.116	1.0	0.019775	-0.083	0.0724	-1.0613	0.125211133224	None	1.0	0.586	0.136095386433	None	0.276747375727	-2.41	0.093	0.177	0.072	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
8798	63	R/T	rs771748059	0.8256	gnomAD-4.0.0	143	None	0.0757	0.0725	19.6	N	0.116	1.0	0.019775	-0.083	0.0724	-1.0613	0.125211133224	None	1.0	0.586	0.136095386433	None	0.276747375727	-2.41	0.093	0.177	0.072	None	None	3.03658E-05	1.33511E-05	6.66844E-05	0	0	None	0	0	3.03658E-05	3.47529E-05	0	4.80292E-05	None	N	None
8799	64	V/M	rs1560601919	0.1336	gnomAD-4.0.0	144	None	0.1693	0.2015	16.03	N	None	-0.63	0.112996	-1.441	0.356	-0.4158	0.184498551638	None	1.0	0.65	0.389283895039	0.295	0.327150285244	-0.88	0.214	0.537	0.065	None	None	6.15807E-06	0	0	0	0	None	0	0	6.15807E-06	8.09545E-06	0	0	None	N	None
8801	66	P/A	rs1220132171	0.5299	gnomAD-2.1.1	146	None	0.0594	0.0707	19.32	N	-0.26	1.01	0.016918	-0.606	0.0651	-1.0837	0.0809317503092	None	1.0	0.546	0.0666544352282	None	0.241247072816	-3.67	0.053	0.106	0.751	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	I	None
8801	66	P/A	rs1220132171	0.5299	gnomAD-4.0.0	146	None	0.0594	0.0707	19.32	N	-0.26	1.01	0.016918	-0.606	0.0651	-1.0837	0.0809317503092	None	1.0	0.546	0.0666544352282	None	0.241247072816	-3.67	0.053	0.106	0.751	None	None	3.18267E-06	0	2.28655E-05	0	0	None	0	0	3.18267E-06	2.85848E-06	0	0	None	I	None
8801	66	P/L	rs778967914	0.5299	gnomAD-2.1.1	146	None	0.0702	0.0866	21.3	N	-0.145	1.07	0.042009	-0.357	0.0943	-1.0458	0.0851352158215	None	0.738473	0.534	0.244539031024	None	0.260859370232	-5.27	0.106	0.207	0.305	None	None	8.05E-06	0	0	0	0	None	6.54E-05	None	8.05E-06	0	0	0	None	I	None
8801	66	P/L	rs778967914	0.5299	gnomAD-4.0.0	146	None	0.0702	0.0866	21.3	N	-0.145	1.07	0.042009	-0.357	0.0943	-1.0458	0.0851352158215	None	0.738473	0.534	0.244539031024	None	0.260859370232	-5.27	0.106	0.207	0.305	None	None	4.10536E-06	0	0	0	0	None	0	0	4.10536E-06	0	6.95668E-05	0	None	I	None
8801	66	P/T	None	0.5299	gnomAD-4.0.0	146	None	0.0657	0.0861	19.84	N	None	0.97	0.017086	-0.655	0.0886	-1.0423	0.0931662067262	None	1.0	0.549	0.104622674875	None	0.246818393469	-3.53	0.062	0.096	0.57	None	None	3.18267E-06	0	0	0	0	None	0	0	3.18267E-06	0	2.86566E-05	0	None	I	None
8802	67	A/D	rs1292226345	0.3668	gnomAD-2.1.1	148	None	0.1501	0.1454	22.8	N	-0.737	1.08	0.033015	-0.661	0.0879	-1.0495	0.130773092448	None	1.0	0.499	0.258283824007	0.013	0.36875975132	-3.11	0.096	0.337	0.615	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
8802	67	A/D	rs1292226345	0.3668	gnomAD-4.0.0	148	None	0.1501	0.1454	22.8	N	-0.737	1.08	0.033015	-0.661	0.0879	-1.0495	0.130773092448	None	1.0	0.499	0.258283824007	0.013	0.36875975132	-3.11	0.096	0.337	0.615	None	None	1.59134E-06	0	0	0	0	None	0	0	1.59134E-06	2.85853E-06	0	0	None	N	None
8803	68	N/S	rs12693164	0.2328	gnomAD-2.1.1	149	None	0.0575	0.0652	None	N	-0.869	None	None	-1.128	None	None	None	None	None	None	None	0.018	None	None	0.186	0.345	None	None	None	1.77519E-01	1.62461E-01	1.76252E-01	1.26429E-01	4.30533E-01	None	2.31679E-01	None	1.77519E-01	9.44995E-02	1.50207E-01	1.63854E-01	None	N	None
8803	68	N/S	rs12693164	0.2328	gnomAD-3.1.2	149	None	0.0575	0.0652	None	N	-0.869	None	None	-1.128	None	None	None	None	None	None	None	0.018	None	None	0.186	0.345	None	None	None	1.68341E-01	1.63632E-01	1.73939E-01	1.3076E-01	4.34414E-01	None	9.80965E-02	1.23418E-01	1.68341E-01	1.5406E-01	2.33637E-01	1.68582E-01	None	N	None
8803	68	N/S	rs12693164	0.2328	1000 genomes	149	None	0.0575	0.0652	None	N	-0.869	None	None	-1.128	None	None	None	None	None	None	None	0.018	None	None	0.186	0.345	None	None	None	2.47005E-01	1.936E-01	1.859E-01	None	4.365E-01	1.561E-01	None	None	2.47005E-01	None	2.607E-01	None	None	N	None
8803	68	N/S	rs12693164	0.2328	gnomAD-4.0.0	149	None	0.0575	0.0652	None	N	-0.869	None	None	-1.128	None	None	None	None	None	None	None	0.018	None	None	0.186	0.345	None	None	None	1.64667E-01	1.64431E-01	1.76194E-01	1.28514E-01	4.42963E-01	None	9.425E-02	2.04193E-01	1.64667E-01	1.52411E-01	2.29363E-01	1.72119E-01	None	N	None
8804	69	A/P	rs778012263	0.2411	gnomAD-3.1.2	151	None	0.5233	0.6362	22.2	D	None	-0.37	0.042805	-0.409	0.3428	-0.4905	0.185621216089	None	1.0	0.6	0.339074221408	0.384	0.437775373459	-3.44	0.333	0.684	0.074	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
8804	69	A/P	rs778012263	0.2411	gnomAD-4.0.0	151	None	0.5233	0.6362	22.2	D	None	-0.37	0.042805	-0.409	0.3428	-0.4905	0.185621216089	None	1.0	0.6	0.339074221408	0.384	0.437775373459	-3.44	0.333	0.684	0.074	None	None	1.85913E-06	0	0	0	0	None	0	0	1.85913E-06	2.5429E-06	0	0	None	N	None
8804	69	A/S	rs778012263	0.2411	gnomAD-2.1.1	151	None	0.0896	0.0889	21.4	N	-0.952	-0.18	0.017092	-0.858	0.1221	-1.0069	0.0767123397799	None	1.0	0.413	0.18274738541	None	0.3782723248	-1.92	0.05	0.348	0.312	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
8805	70	G/R	rs756620595	0.1962	gnomAD-2.1.1	152	None	0.7889	0.8925	24.1	D	-0.443	-1.11	0.058986	-0.732	0.8011	0.862	0.506463245118	None	0.999836	0.929	0.890888985325	1.0	0.682042479515	-5.26	0.705	0.823	0.003	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	I	None
8805	70	G/R	rs756620595	0.1962	gnomAD-4.0.0	152	None	0.7889	0.8925	24.1	D	-0.443	-1.11	0.058986	-0.732	0.8011	0.862	0.506463245118	None	0.999836	0.929	0.890888985325	1.0	0.682042479515	-5.26	0.705	0.823	0.003	None	None	1.59136E-06	5.65867E-05	0	0	0	None	0	0	1.59136E-06	0	0	0	None	I	None
8808	73	T/A	None	0.1269	gnomAD-4.0.0	155	None	0.0851	0.0951	23.2	N	None	0.79	0.028809	-1.263	0.257	-0.5387	0.0966325536962	None	1.0	0.601	0.322230723748	0.089	0.309078544378	-2.95	0.278	0.663	0.048	None	None	1.20033E-06	0	0	0	0	None	0	0	1.20033E-06	1.31251E-06	0	0	None	N	None
8809	74	C/R	rs753253530	0.0638	gnomAD-2.1.1	156	None	0.9787	0.9915	27.7	D	-1.014	-0.12	0.496173	-1.363	0.633	0.6263	0.61613149071	None	1.0	0.849	0.816451128208	1.0	0.733659803867	-8.12	0.768	0.901	0.084	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.9E-06	0	None	N	None
8810	75	Q/H	rs781752797	0.2519	gnomAD-2.1.1	157	None	0.3282	0.4426	21.2	D	-1.302	-0.37	0.086651	-1.055	0.269	-0.5738	0.128479209888	None	1.0	0.501	0.373357554552	0.241	0.499472439289	-2.45	0.304	0.373	0.444	None	None	8.05E-06	0	0	0	0	None	0	None	8.05E-06	4.65E-05	0	1.65948E-04	None	N	None
8810	75	Q/H	rs781752797	0.2519	gnomAD-4.0.0	157	None	0.3282	0.4426	21.2	D	-1.302	-0.37	0.086651	-1.055	0.269	-0.5738	0.128479209888	None	1.0	0.501	0.373357554552	0.241	0.499472439289	-2.45	0.304	0.373	0.444	None	None	9.57938E-06	0	0	0	0	None	3.7456E-05	0	9.57938E-06	2.69853E-06	0	1.49081E-04	None	N	None
8810	75	Q/L	rs934473433	0.2519	gnomAD-2.1.1	157	None	0.1803	0.2289	26.2	D	0.187	-0.34	0.08567	0.298	0.4059	-0.1882	0.381570733968	None	0.839007	0.54	0.554881495044	0.989	0.457045376301	-4.1	0.434	0.642	0.642	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.9E-06	0	None	N	None
8810	75	Q/L	rs934473433	0.2519	gnomAD-3.1.2	157	None	0.1803	0.2289	26.2	D	0.187	-0.34	0.08567	0.298	0.4059	-0.1882	0.381570733968	None	0.839007	0.54	0.554881495044	0.989	0.457045376301	-4.1	0.434	0.642	0.642	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
8810	75	Q/L	rs934473433	0.2519	gnomAD-4.0.0	157	None	0.1803	0.2289	26.2	D	0.187	-0.34	0.08567	0.298	0.4059	-0.1882	0.381570733968	None	0.839007	0.54	0.554881495044	0.989	0.457045376301	-4.1	0.434	0.642	0.642	None	None	5.12471E-06	1.69159E-05	0	0	0	None	0	0	5.12471E-06	7.17992E-06	0	0	None	N	None
8811	76	I/V	rs1346764958	0.0417	gnomAD-2.1.1	158	None	0.0838	0.1105	22.1	N	-2.293	0.06	0.027421	-1.901	0.1155	-0.9987	0.0719583658917	None	1.0	0.499	0.327419511103	0.001	0.416546583176	-0.58	0.104	0.261	0.76	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.9E-06	0	None	N	None
8811	76	I/V	rs1346764958	0.0417	gnomAD-4.0.0	158	None	0.0838	0.1105	22.1	N	-2.293	0.06	0.027421	-1.901	0.1155	-0.9987	0.0719583658917	None	1.0	0.499	0.327419511103	0.001	0.416546583176	-0.58	0.104	0.261	0.76	None	None	4.8013E-06	0	0	0	0	None	0	0	4.8013E-06	5.25002E-06	0	0	None	N	None
8813	78	N/S	rs2077136991	0.1610	gnomAD-4.0.0	161	None	0.5983	0.7642	24.0	N	None	0.32	0.039882	-0.841	0.5017	0.2137	0.417388960371	None	0.870595	0.888	0.372446077551	0.999	0.472286820412	-2.88	0.622	0.561	0.187	None	None	1.5916E-06	0	0	0	0	None	0	0	1.5916E-06	2.85915E-06	0	0	None	N	None
8814	79	D/N	rs1035364658	0.7902	gnomAD-2.1.1	162	None	0.0992	0.1209	25.2	N	0.593	-0.23	0.041701	0.395	0.5258	0.0537	0.436835409968	None	0.538632	0.398	0.476676017676	0.999	0.559704780579	-2.93	0.324	0.587	0.087	None	None	4.02E-06	0	2.9E-05	0	0	None	0	None	4.02E-06	0	0	0	None	I	None
8814	79	D/N	rs1035364658	0.7902	gnomAD-4.0.0	162	None	0.0992	0.1209	25.2	N	0.593	-0.23	0.041701	0.395	0.5258	0.0537	0.436835409968	None	0.538632	0.398	0.476676017676	0.999	0.559704780579	-2.93	0.324	0.587	0.087	None	None	1.59175E-06	0	2.28666E-05	0	0	None	0	0	1.59175E-06	0	0	0	None	I	None
8814	79	D/Y	rs1035364658	0.7902	gnomAD-3.1.2	162	None	0.2226	0.3056	25.2	N	None	-0.27	0.044525	0.078	0.549	0.1126	0.511382231021	None	0.858804	0.429	0.633624541524	1.0	0.565027058125	-5.29	0.378	0.734	0.009	None	None	6.57E-06	0	0	0	1.92901E-04	None	0	0	6.57E-06	0	0	0	None	I	None
8814	79	D/Y	rs1035364658	0.7902	gnomAD-4.0.0	162	None	0.2226	0.3056	25.2	N	None	-0.27	0.044525	0.078	0.549	0.1126	0.511382231021	None	0.858804	0.429	0.633624541524	1.0	0.565027058125	-5.29	0.378	0.734	0.009	None	None	6.57315E-06	0	0	0	1.92901E-04	None	0	0	6.57315E-06	0	0	0	None	I	None
8815	80	A/G	rs1168744166	0.5762	gnomAD-2.1.1	163	None	0.1447	0.1699	24.4	N	-0.041	-0.34	0.080251	-0.203	0.5248	0.0361	0.460205153968	None	0.999109	0.647	0.442875378763	0.998	0.470773488283	-2.63	0.471	0.606	0.401	None	None	7.15E-06	0	0	0	0	None	0	None	7.15E-06	0	1.56E-05	0	None	I	None
8815	80	A/G	rs1168744166	0.5762	gnomAD-3.1.2	163	None	0.1447	0.1699	24.4	N	-0.041	-0.34	0.080251	-0.203	0.5248	0.0361	0.460205153968	None	0.999109	0.647	0.442875378763	0.998	0.470773488283	-2.63	0.471	0.606	0.401	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	1.47E-05	0	4.77555E-04	None	I	None
8815	80	A/G	rs1168744166	0.5762	gnomAD-4.0.0	163	None	0.1447	0.1699	24.4	N	-0.041	-0.34	0.080251	-0.203	0.5248	0.0361	0.460205153968	None	0.999109	0.647	0.442875378763	0.998	0.470773488283	-2.63	0.471	0.606	0.401	None	None	8.96895E-06	1.68856E-05	0	0	0	None	0	0	8.96895E-06	9.57648E-06	0	5.68408E-05	None	I	None
8815	80	A/V	rs1168744166	0.5762	gnomAD-2.1.1	163	None	0.1729	0.1992	24.4	N	0.004	-0.24	0.076511	-0.322	0.4201	-0.2274	0.461264151035	None	0.999309	0.597	0.45235992198	1.0	0.498854458332	-2.43	0.404	0.678	0.454	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	I	None
8815	80	A/V	rs1168744166	0.5762	gnomAD-4.0.0	163	None	0.1729	0.1992	24.4	N	0.004	-0.24	0.076511	-0.322	0.4201	-0.2274	0.461264151035	None	0.999309	0.597	0.45235992198	1.0	0.498854458332	-2.43	0.404	0.678	0.454	None	None	3.18348E-06	0	0	0	0	None	0	0	3.18348E-06	0	2.8659E-05	0	None	I	None
8817	82	M/I	rs1427255919	0.5214	gnomAD-2.1.1	165	None	0.166	0.1555	18.34	N	-0.281	-0.22	0.031923	-0.646	0.1397	-0.8781	0.0925954833539	None	1.0	0.477	0.472181857204	None	0.354805707932	-1.49	0.205	0.107	0.201	None	None	8.05E-06	0	0	0	0	None	3.27E-05	None	8.05E-06	0	8.9E-06	0	None	I	None
8817	82	M/I	rs1427255919	0.5214	gnomAD-4.0.0	165	None	0.166	0.1555	18.34	N	-0.281	-0.22	0.031923	-0.646	0.1397	-0.8781	0.0925954833539	None	1.0	0.477	0.472181857204	None	0.354805707932	-1.49	0.205	0.107	0.201	None	None	3.18436E-06	0	0	0	0	None	0	0	3.18436E-06	2.86071E-06	1.43316E-05	0	None	I	None
8817	82	M/T	rs1469529188	0.5214	gnomAD-2.1.1	165	None	0.104	0.1205	16.58	N	-0.033	-0.14	0.021526	-0.469	0.0889	-1.0554	0.0966260119837	None	0.999875	0.4	0.400468435593	None	0.42724108696	-2.15	0.123	0.154	1.0	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.89E-06	0	None	I	None
8817	82	M/T	rs1469529188	0.5214	gnomAD-4.0.0	165	None	0.104	0.1205	16.58	N	-0.033	-0.14	0.021526	-0.469	0.0889	-1.0554	0.0966260119837	None	0.999875	0.4	0.400468435593	None	0.42724108696	-2.15	0.123	0.154	1.0	None	None	9.58085E-06	0	0	0	0	None	0	0	9.58085E-06	1.25956E-05	0	0	None	I	None
8817	82	M/V	rs878856898	0.5214	gnomAD-4.0.0	165	None	0.0768	0.0746	14.66	N	None	-0.2	0.016114	-0.809	0.1213	-1.0112	0.0848295226273	None	0.99999	0.438	0.395143324098	None	0.319042682648	-1.26	0.081	0.105	0.52	None	None	1.5918E-06	0	0	0	0	None	0	0	1.5918E-06	2.85981E-06	0	0	None	I	None
8818	83	Q/K	rs2077133872	0.3440	gnomAD-3.1.2	166	None	0.1023	0.1042	21.8	N	None	-0.22	0.069859	-0.436	0.247	-0.6078	0.155803617009	None	1.0	0.57	0.273938319068	0.556	0.459689408541	-2.06	0.233	0.291	0.648	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
8818	83	Q/K	rs2077133872	0.3440	gnomAD-4.0.0	166	None	0.1023	0.1042	21.8	N	None	-0.22	0.069859	-0.436	0.247	-0.6078	0.155803617009	None	1.0	0.57	0.273938319068	0.556	0.459689408541	-2.06	0.233	0.291	0.648	None	None	2.56377E-06	0	0	0	0	None	0	0	2.56377E-06	4.78964E-06	0	0	None	I	None
8819	84	E/D	rs1242327696	0.2231	gnomAD-2.1.1	168	None	0.2165	0.2318	21.5	N	-1.243	-0.44	0.032024	-1.202	0.2781	-0.4173	0.199548353779	None	1.0	0.469	0.358540694251	0.942	0.513894319534	-1.77	0.358	0.447	0.217	None	None	1.91058E-04	0	0	0	0	None	0	None	1.91058E-04	0	3.88752E-04	0	None	N	None
8819	84	E/D	rs1242327696	0.2231	gnomAD-3.1.2	168	None	0.2165	0.2318	21.5	N	-1.243	-0.44	0.032024	-1.202	0.2781	-0.4173	0.199548353779	None	1.0	0.469	0.358540694251	0.942	0.513894319534	-1.77	0.358	0.447	0.217	None	None	4.6E-05	0	0	0	0	None	0	0	4.6E-05	1.02926E-04	0	0	None	N	None
8819	84	E/D	rs1242327696	0.2231	gnomAD-4.0.0	168	None	0.2165	0.2318	21.5	N	-1.243	-0.44	0.032024	-1.202	0.2781	-0.4173	0.199548353779	None	1.0	0.469	0.358540694251	0.942	0.513894319534	-1.77	0.358	0.447	0.217	None	None	4.60109E-05	0	0	0	0	None	0	0	4.60109E-05	1.02926E-04	0	0	None	N	None
8819	84	E/K	rs1452521377	0.2231	gnomAD-4.0.0	168	None	0.2636	0.2887	23.8	N	None	-0.36	0.076922	-0.911	0.437	-0.1501	0.376282646493	None	0.564081	0.623	0.508223314113	0.996	0.596366167068	-2.19	0.412	0.445	0.545	None	None	2.73754E-06	0	0	0	0	None	0	0	2.73754E-06	3.5989E-06	0	0	None	N	None
8820	85	C/G	rs1193461740	0.1057	gnomAD-3.1.2	169	None	0.1471	0.1557	26.4	N	None	-0.26	0.146708	-2.362	0.5042	0.0691	0.516649995381	None	0.997263	0.567	0.817221544248	0.999	0.580526232719	-6.75	0.555	0.861	0.011	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
8820	85	C/G	rs1193461740	0.1057	gnomAD-4.0.0	169	None	0.1471	0.1557	26.4	N	None	-0.26	0.146708	-2.362	0.5042	0.0691	0.516649995381	None	0.997263	0.567	0.817221544248	0.999	0.580526232719	-6.75	0.555	0.861	0.011	None	None	6.57592E-06	2.41441E-05	0	0	0	None	0	0	6.57592E-06	0	0	0	None	N	None
8820	85	C/Y	rs778500616	0.1057	gnomAD-2.1.1	169	None	0.3364	0.3696	24.9	N	-1.522	-0.27	0.110543	-1.264	0.5566	0.1638	0.601348376114	None	0.999494	0.55	0.746340679362	1.0	0.690894126892	-6.06	0.439	0.915	0.003	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.89E-06	0	None	N	None
8820	85	C/Y	rs778500616	0.1057	gnomAD-4.0.0	169	None	0.3364	0.3696	24.9	N	-1.522	-0.27	0.110543	-1.264	0.5566	0.1638	0.601348376114	None	0.999494	0.55	0.746340679362	1.0	0.690894126892	-6.06	0.439	0.915	0.003	None	None	1.59325E-06	0	0	0	0	None	0	0	1.59325E-06	2.86364E-06	0	0	None	N	None
8822	87	A/S	None	0.1575	gnomAD-4.0.0	172	None	0.1228	0.14	22.5	N	None	-0.49	0.139983	-1.683	0.4702	-0.0267	0.322070072884	None	0.84353	0.64	0.273070737957	0.694	0.41460698843	-1.59	0.427	0.547	0.118	None	None	2.73873E-06	0	0	0	0	None	0	0	2.73873E-06	9.00163E-07	2.31976E-05	1.65722E-05	None	N	None
8822	87	A/T	rs184883436	0.1575	gnomAD-2.1.1	172	None	0.163	0.212	None	N	-1.271	None	None	-1.424	None	None	None	None	None	None	None	0.392	None	None	0.37	0.391	None	None	None	9.29E-05	0	1.98098E-04	0	1.02407E-04	None	1.96412E-04	None	9.29E-05	0	8.61E-05	0	None	N	None
8822	87	A/T	rs184883436	0.1575	gnomAD-3.1.2	172	None	0.163	0.212	None	N	-1.271	None	None	-1.424	None	None	None	None	None	None	None	0.392	None	None	0.37	0.391	None	None	None	4.6E-05	2.41E-05	0	0	7.73994E-04	None	0	0	4.6E-05	1.47E-05	2.07039E-04	0	None	N	None
8822	87	A/T	rs184883436	0.1575	gnomAD-4.0.0	172	None	0.163	0.212	None	N	-1.271	None	None	-1.424	None	None	None	None	None	None	None	0.392	None	None	0.37	0.391	None	None	None	5.76658E-05	1.3339E-05	2.0002E-04	0	2.67618E-04	None	0	0	5.76658E-05	4.24118E-05	1.64759E-04	4.80384E-05	None	N	None
8822	87	A/V	rs753291479	0.1575	gnomAD-2.1.1	172	None	0.2816	0.3869	25.1	D	-0.256	-0.33	0.112814	-0.184	0.3085	-0.4012	0.231264525672	None	0.994448	0.611	0.488897681448	0.977	0.451442241669	-2.5	0.421	0.595	0.019	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.89E-06	0	None	N	None
8822	87	A/V	rs753291479	0.1575	gnomAD-4.0.0	172	None	0.2816	0.3869	25.1	D	-0.256	-0.33	0.112814	-0.184	0.3085	-0.4012	0.231264525672	None	0.994448	0.611	0.488897681448	0.977	0.451442241669	-2.5	0.421	0.595	0.019	None	None	1.57463E-05	0	0	0	0	None	0	0	1.57463E-05	1.98016E-05	0	1.65711E-05	None	N	None
8823	88	T/K	rs368151971	0.3539	gnomAD-2.1.1	173	None	0.1354	0.1373	11.52	N	-0.326	-0.23	0.027905	-0.704	0.1649	-0.9536	0.101150159241	None	0.99998	0.536	0.0986583533028	0.002	0.2476695925	-2.44	0.229	0.166	0.912	None	None	4.03E-06	0	0	0	5.56E-05	None	0	None	4.03E-06	0	0	0	None	N	None
8823	88	T/K	rs368151971	0.3539	gnomAD-4.0.0	173	None	0.1354	0.1373	11.52	N	-0.326	-0.23	0.027905	-0.704	0.1649	-0.9536	0.101150159241	None	0.99998	0.536	0.0986583533028	0.002	0.2476695925	-2.44	0.229	0.166	0.912	None	None	6.84809E-07	0	0	0	2.52054E-05	None	0	0	6.84809E-07	0	0	0	None	N	None
8823	88	T/M	rs368151971	0.3539	gnomAD-2.1.1	173	None	0.0667	0.0714	None	D	-0.109	None	None	-0.174	None	None	None	None	None	None	None	0.186	None	None	0.156	0.267	None	None	None	2.01E-05	1.29266E-04	0	0	0	None	0	None	2.01E-05	0	2.67E-05	0	None	N	None
8823	88	T/M	rs368151971	0.3539	gnomAD-3.1.2	173	None	0.0667	0.0714	None	D	-0.109	None	None	-0.174	None	None	None	None	None	None	None	0.186	None	None	0.156	0.267	None	None	None	5.92E-05	7.24E-05	6.55E-05	0	1.92753E-04	None	0	0	5.92E-05	5.88E-05	0	0	None	N	None
8823	88	T/M	rs368151971	0.3539	1000 genomes	173	None	0.0667	0.0714	None	D	-0.109	None	None	-0.174	None	None	None	None	None	None	None	0.186	None	None	0.156	0.267	None	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	N	None
8823	88	T/M	rs368151971	0.3539	gnomAD-4.0.0	173	None	0.0667	0.0714	None	D	-0.109	None	None	-0.174	None	None	None	None	None	None	None	0.186	None	None	0.156	0.267	None	None	None	1.98452E-05	8.00598E-05	1.66756E-05	0	2.22965E-05	None	0	1.6518E-04	1.98452E-05	1.52711E-05	0	8.00641E-05	None	N	None
8823	88	T/R	None	0.3539	gnomAD-4.0.0	173	None	0.1095	0.1103	11.56	N	None	-0.3	0.036031	-0.536	0.1822	-0.9007	0.139753736602	None	0.99998	0.496	0.345632371893	0.604	0.242871761322	-2.68	0.195	0.561	0.485	None	None	6.84809E-07	0	0	0	0	None	0	0	6.84809E-07	9.00333E-07	0	0	None	N	None
8824	89	L/I	rs1322441627	0.2169	gnomAD-2.1.1	174	None	0.072	0.0807	10.12	N	-0.801	0.08	0.037206	-0.941	0.2399	-0.7491	0.117407629759	None	0.999989	0.723	0.19670166235	0.008	0.313095510006	-1.05	0.141	0.642	0.185	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.48E-05	0	None	N	None
8824	89	L/I	rs1322441627	0.2169	gnomAD-3.1.2	174	None	0.072	0.0807	10.12	N	-0.801	0.08	0.037206	-0.941	0.2399	-0.7491	0.117407629759	None	0.999989	0.723	0.19670166235	0.008	0.313095510006	-1.05	0.141	0.642	0.185	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
8824	89	L/I	rs1322441627	0.2169	gnomAD-4.0.0	174	None	0.072	0.0807	10.12	N	-0.801	0.08	0.037206	-0.941	0.2399	-0.7491	0.117407629759	None	0.999989	0.723	0.19670166235	0.008	0.313095510006	-1.05	0.141	0.642	0.185	None	None	6.57263E-06	0	0	0	0	None	0	0	6.57263E-06	1.46994E-05	0	0	None	N	None
8825	90	S/F	rs2077128629	0.3264	gnomAD-4.0.0	175	None	0.1194	0.1325	22.3	N	None	-0.31	0.024294	-1.082	0.2884	-0.6366	0.0940302031534	None	0.999994	0.539	0.569067374492	0.017	0.427246272564	-3.71	0.297	0.417	0.006	None	None	1.59566E-06	0	0	0	2.775E-05	None	0	0	1.59566E-06	0	0	0	None	N	None
8826	91	V/I	rs200116046	0.2751	gnomAD-2.1.1	178	None	0.0654	0.0733	None	N	-0.82	None	None	-0.706	None	None	None	None	None	None	None	0.001	None	None	0.258	0.471	None	None	None	4.03E-06	0	0	0	0	None	3.28E-05	None	4.03E-06	0	0	0	None	N	None
8826	91	V/I	rs200116046	0.2751	gnomAD-4.0.0	178	None	0.0654	0.0733	None	N	-0.82	None	None	-0.706	None	None	None	None	None	None	None	0.001	None	None	0.258	0.471	None	None	None	2.74088E-06	0	0	0	0	None	0	0	2.74088E-06	2.70241E-06	1.16085E-05	0	None	N	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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