TITINdb

Map SAVs to Structure

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
6574	1	P/Q	1	None	0.1340	None	gnomAD-4.0.0	1.67444E-06
6575	2	S/N	2	rs560328343	0.3003	None	gnomAD-3.1.2	6.58E-06
6575	2	S/N	2	rs560328343	0.3003	None	1000 genomes	1.99681E-04
6575	2	S/N	2	rs560328343	0.3003	None	gnomAD-4.0.0	1.26495E-06
6575	2	S/T	2	None	0.3003	None	gnomAD-4.0.0	1.39967E-06
6578	5	V/L	5	rs2079625925	0.3761	None	gnomAD-3.1.2	6.58E-06
6578	5	V/L	5	rs2079625925	0.3761	None	gnomAD-4.0.0	6.57618E-06
6578	5	V/M	5	None	0.3761	None	gnomAD-4.0.0	1.6504E-06
6579	6	K/N	7	rs1578112424	0.5391	None	gnomAD-4.0.0	3.27721E-06
6580	7	P/S	8	rs116572520	0.2321	None	gnomAD-2.1.1	6.00326E-04
6580	7	P/S	8	rs116572520	0.2321	None	gnomAD-3.1.2	1.81524E-03
6580	7	P/S	8	rs116572520	0.2321	None	1000 genomes	3.39457E-03
6580	7	P/S	8	rs116572520	0.2321	None	gnomAD-4.0.0	3.29817E-04
6580	7	P/T	8	rs116572520	0.2321	None	gnomAD-2.1.1	8.51E-06
6580	7	P/T	8	rs116572520	0.2321	None	gnomAD-4.0.0	1.38633E-06
6582	9	R/Q	11	rs776051087	0.8553	None	gnomAD-2.1.1	2.96E-05
6582	9	R/Q	11	rs776051087	0.8553	None	gnomAD-3.1.2	5.92E-05
6582	9	R/Q	11	rs776051087	0.8553	None	gnomAD-4.0.0	2.81502E-05
6583	10	Q/R	13	rs1370326075	0.2980	None	gnomAD-4.0.0	1.61836E-06
6584	11	Q/K	14	rs908969278	0.7603	None	gnomAD-4.0.0	1.20032E-06
6585	12	A/T	16	None	0.1852	None	gnomAD-4.0.0	1.20032E-06
6586	13	I/T	18	rs896710187	0.7702	None	gnomAD-3.1.2	6.57E-06
6586	13	I/T	18	rs896710187	0.7702	None	gnomAD-4.0.0	6.21717E-06
6586	13	I/V	18	None	0.7702	None	gnomAD-4.0.0	1.20032E-06
6587	14	P/R	23	rs2079621657	0.4526	None	gnomAD-4.0.0	1.60498E-06
6587	14	P/T	23	None	0.4526	None	gnomAD-4.0.0	6.86684E-07
6588	15	D/H	24	None	0.7999	None	gnomAD-4.0.0	6.85357E-06
6588	15	D/N	24	None	0.7999	None	gnomAD-4.0.0	6.85357E-07
6589	16	S/C	25	rs1206769574	0.2475	None	gnomAD-2.1.1	4.04E-06
6589	16	S/C	25	rs1206769574	0.2475	None	gnomAD-4.0.0	6.84978E-07
6589	16	S/Y	25	None	0.2475	None	gnomAD-4.0.0	6.84978E-07
6590	17	T/A	26	rs1296238597	0.4290	None	gnomAD-2.1.1	4.04E-06
6590	17	T/A	26	rs1296238597	0.4290	None	gnomAD-4.0.0	1.59523E-06
6590	17	T/I	26	rs760473000	0.4290	None	gnomAD-2.1.1	1.62E-05
6590	17	T/I	26	rs760473000	0.4290	None	gnomAD-4.0.0	4.79518E-06
6591	18	V/G	28	rs2079619288	0.1815	None	gnomAD-3.1.2	6.57E-06
6591	18	V/G	28	rs2079619288	0.1815	None	gnomAD-4.0.0	2.56654E-06
6595	22	A/T	33	rs1305423472	0.1049	None	gnomAD-2.1.1	7.16E-06
6595	22	A/T	33	rs1305423472	0.1049	None	gnomAD-3.1.2	6.58E-06
6595	22	A/T	33	rs1305423472	0.1049	None	gnomAD-4.0.0	2.48042E-06
6596	23	I/M	34	rs2079617659	0.2973	None	gnomAD-4.0.0	1.59302E-06
6596	23	I/T	34	None	0.2973	None	gnomAD-4.0.0	1.20032E-06
6596	23	I/V	34	rs369108292	0.2973	None	gnomAD-2.1.1	8.06E-06
6596	23	I/V	34	rs369108292	0.2973	None	gnomAD-3.1.2	2.63E-05
6596	23	I/V	34	rs369108292	0.2973	None	gnomAD-4.0.0	4.34001E-06
6597	24	L/I	35	None	0.1436	None	gnomAD-4.0.0	6.00161E-06
6597	24	L/P	35	rs745676008	0.1436	None	gnomAD-2.1.1	4.03E-06
6597	24	L/P	35	rs745676008	0.1436	None	gnomAD-4.0.0	2.6012E-05
6599	26	G/E	40	None	0.1699	None	gnomAD-4.0.0	2.40064E-06
6600	27	T/A	41	rs530353051	0.2759	None	gnomAD-2.1.1	2.82E-05
6600	27	T/A	41	rs530353051	0.2759	None	gnomAD-3.1.2	1.97E-05
6600	27	T/A	41	rs530353051	0.2759	None	1000 genomes	1.99681E-04
6600	27	T/A	41	rs530353051	0.2759	None	gnomAD-4.0.0	1.6664E-05
6600	27	T/I	41	rs1355564295	0.2759	None	gnomAD-2.1.1	4.02E-06
6600	27	T/I	41	rs1355564295	0.2759	None	gnomAD-4.0.0	2.40065E-06
6601	28	P/L	42	None	0.4870	None	gnomAD-4.0.0	6.84477E-07
6601	28	P/Q	42	rs1578111426	0.4870	None	gnomAD-4.0.0	6.84477E-07
6601	28	P/S	42	rs1175980116	0.4870	None	gnomAD-2.1.1	4.02E-06
6601	28	P/S	42	rs1175980116	0.4870	None	gnomAD-3.1.2	1.32E-05
6601	28	P/S	42	rs1175980116	0.4870	None	gnomAD-4.0.0	6.81922E-06
6602	29	P/Q	43	rs749229040	0.7534	None	gnomAD-2.1.1	4.02E-06
6602	29	P/Q	43	rs749229040	0.7534	None	gnomAD-4.0.0	6.3705E-06
6602	29	P/R	43	rs749229040	0.7534	None	gnomAD-3.1.2	1.32E-05
6602	29	P/R	43	rs749229040	0.7534	None	gnomAD-4.0.0	1.31506E-05
6602	29	P/S	43	None	0.7534	None	gnomAD-4.0.0	1.5926E-06
6605	32	I/M	46	None	0.2570	None	gnomAD-4.0.0	1.20034E-06
6607	34	W/R	48	None	0.1168	None	gnomAD-4.0.0	1.20032E-06
6608	35	F/C	49	None	0.1560	None	gnomAD-4.0.0	3.18464E-06
6608	35	F/L	49	None	0.1560	None	gnomAD-4.0.0	6.84402E-07
6609	36	K/N	50	rs781410754	0.1465	None	gnomAD-2.1.1	6.84E-05
6609	36	K/N	50	rs781410754	0.1465	None	gnomAD-3.1.2	2.63E-05
6609	36	K/N	50	rs781410754	0.1465	None	gnomAD-4.0.0	1.3688E-06
6609	36	K/R	50	rs756188488	0.1465	None	gnomAD-2.1.1	1.61E-05
6609	36	K/R	50	rs756188488	0.1465	None	gnomAD-3.1.2	1.31E-05
6609	36	K/R	50	rs756188488	0.1465	None	gnomAD-4.0.0	7.69059E-06
6610	37	D/E	51	None	0.4218	None	gnomAD-4.0.0	1.59229E-06
6610	37	D/G	51	None	0.4218	None	gnomAD-4.0.0	6.84404E-07
6610	37	D/H	51	None	0.4218	None	gnomAD-4.0.0	3.18461E-06
6610	37	D/V	51	rs755182614	0.4218	None	gnomAD-2.1.1	4.02E-06
6610	37	D/V	51	rs755182614	0.4218	None	gnomAD-4.0.0	6.84404E-07
6611	38	D/G	52	None	0.9304	None	gnomAD-4.0.0	1.20032E-06
6611	38	D/N	52	None	0.9304	None	gnomAD-4.0.0	1.20032E-06
6612	39	V/A	55	None	0.5794	None	gnomAD-4.0.0	6.84395E-07
6612	39	V/E	55	rs751909040	0.5794	None	gnomAD-2.1.1	4.02E-06
6612	39	V/E	55	rs751909040	0.5794	None	gnomAD-4.0.0	1.36879E-06
6612	39	V/M	55	None	0.5794	None	gnomAD-4.0.0	1.59229E-06
6614	41	L/I	58	rs758885175	0.2294	None	gnomAD-2.1.1	4.02E-06
6614	41	L/I	58	rs758885175	0.2294	None	gnomAD-4.0.0	1.59225E-06
6615	42	V/L	59	None	0.8030	None	gnomAD-4.0.0	8.21269E-06
6617	44	G/D	73	rs371847228	0.3795	None	gnomAD-2.1.1	6.78E-05
6617	44	G/D	73	rs371847228	0.3795	None	gnomAD-3.1.2	2.17025E-04
6617	44	G/D	73	rs371847228	0.3795	None	gnomAD-4.0.0	3.53334E-05
6618	45	P/A	102	None	0.9080	None	gnomAD-4.0.0	1.36878E-06
6618	45	P/L	102	None	0.9080	None	gnomAD-4.0.0	3.18465E-06
6618	45	P/S	102	rs1234787097	0.9080	None	gnomAD-2.1.1	4.02E-06
6618	45	P/S	102	rs1234787097	0.9080	None	gnomAD-4.0.0	6.84391E-07
6619	46	K/E	115	rs1060500450	0.8141	None	gnomAD-2.1.1	4.02E-06
6619	46	K/E	115	rs1060500450	0.8141	None	gnomAD-3.1.2	1.97E-05
6619	46	K/E	115	rs1060500450	0.8141	None	gnomAD-4.0.0	1.1536E-05
6619	46	K/T	115	rs368720026	0.8141	None	gnomAD-2.1.1	8.04E-06
6619	46	K/T	115	rs368720026	0.8141	None	gnomAD-3.1.2	5.92E-05
6619	46	K/T	115	rs368720026	0.8141	None	gnomAD-4.0.0	1.79463E-05
6620	47	C/F	121	None	0.1632	None	gnomAD-4.0.0	6.84404E-07
6620	47	C/R	121	rs1470771648	0.1632	None	gnomAD-3.1.2	6.57E-06
6620	47	C/R	121	rs1470771648	0.1632	None	gnomAD-4.0.0	6.5735E-06
6620	47	C/Y	121	rs935626596	0.1632	None	gnomAD-2.1.1	1.61E-05
6620	47	C/Y	121	rs935626596	0.1632	None	gnomAD-4.0.0	6.15963E-06
6621	48	F/L	122	rs760276555	0.4564	None	gnomAD-2.1.1	8.04E-06
6621	48	F/L	122	rs760276555	0.4564	None	gnomAD-4.0.0	4.77693E-06
6622	49	I/F	123	rs775092361	0.1958	None	gnomAD-2.1.1	4.02E-06
6622	49	I/N	123	rs1413452032	0.1958	None	gnomAD-2.1.1	4.02E-06
6622	49	I/N	123	rs1413452032	0.1958	None	gnomAD-4.0.0	1.59231E-06
6624	51	L/F	127	rs78279193	0.3540	None	gnomAD-4.0.0	3.18506E-06
6626	53	G/E	131	rs1362220931	0.5162	None	gnomAD-2.1.1	4.02E-06
6626	53	G/R	131	rs770749098	0.5162	None	gnomAD-2.1.1	4.02E-06
6626	53	G/R	131	rs770749098	0.5162	None	gnomAD-4.0.0	1.59237E-06
6626	53	G/V	131	rs1362220931	0.5162	None	gnomAD-4.0.0	1.20032E-06
6627	54	S/L	134	rs773143754	0.3352	None	gnomAD-2.1.1	1.43E-05
6627	54	S/L	134	rs773143754	0.3352	None	gnomAD-3.1.2	6.58E-06
6627	54	S/L	134	rs773143754	0.3352	None	gnomAD-4.0.0	9.919E-06
6628	55	T/P	135	None	0.1453	None	gnomAD-4.0.0	6.00161E-06
6629	56	S/G	136	rs1484625101	0.1137	None	gnomAD-2.1.1	4.02E-06
6629	56	S/G	136	rs1484625101	0.1137	None	gnomAD-4.0.0	1.59241E-06
6629	56	S/I	136	rs2079601523	0.1137	None	gnomAD-3.1.2	6.58E-06
6629	56	S/I	136	rs2079601523	0.1137	None	gnomAD-4.0.0	6.57748E-06
6630	57	F/L	137	rs1259557024	0.1963	None	gnomAD-2.1.1	4.02E-06
6630	57	F/L	137	rs1259557024	0.1963	None	gnomAD-3.1.2	1.31E-05
6630	57	F/L	137	rs1259557024	0.1963	None	gnomAD-4.0.0	5.12771E-06
6630	57	F/V	137	rs1259557024	0.1963	None	gnomAD-3.1.2	6.57E-06
6630	57	F/V	137	rs1259557024	0.1963	None	gnomAD-4.0.0	2.56385E-06
6631	58	L/S	138	None	0.0760	None	gnomAD-4.0.0	1.36887E-06
6634	61	Y/C	141	rs2079599735	0.3920	None	gnomAD-3.1.2	6.58E-06
6634	61	Y/C	141	rs2079599735	0.3920	None	gnomAD-4.0.0	7.10648E-06
6634	61	Y/H	141	rs1211263186	0.3920	None	gnomAD-2.1.1	8.04E-06
6634	61	Y/H	141	rs1211263186	0.3920	None	gnomAD-4.0.0	4.77779E-06
6636	63	V/A	144	rs1258812731	0.1278	None	gnomAD-2.1.1	1.61E-05
6636	63	V/A	144	rs1258812731	0.1278	None	gnomAD-4.0.0	4.77824E-06
6637	64	D/G	145	rs1240731918	0.3595	None	gnomAD-2.1.1	4.03E-06
6637	64	D/G	145	rs1240731918	0.3595	None	gnomAD-3.1.2	1.32E-05
6637	64	D/G	145	rs1240731918	0.3595	None	gnomAD-4.0.0	1.31546E-05
6637	64	D/V	145	None	0.3595	None	gnomAD-4.0.0	1.20032E-06
6637	64	D/Y	145	None	0.3595	None	gnomAD-4.0.0	1.20032E-06
6638	65	A/T	146	rs878890344	0.5274	None	gnomAD-3.1.2	6.58E-06
6638	65	A/T	146	rs878890344	0.5274	None	gnomAD-4.0.0	3.72E-06
6640	67	K/E	149	None	0.2408	None	gnomAD-4.0.0	1.20032E-06
6641	68	T/A	151	None	0.3214	None	gnomAD-4.0.0	1.5932E-06
6641	68	T/I	151	rs747240394	0.3214	None	gnomAD-3.1.2	6.58E-06
6641	68	T/I	151	rs747240394	0.3214	None	gnomAD-4.0.0	6.57601E-06
6641	68	T/N	151	rs747240394	0.3214	None	gnomAD-2.1.1	2.93278E-04
6641	68	T/N	151	rs747240394	0.3214	None	gnomAD-3.1.2	7.23E-05
6641	68	T/N	151	rs747240394	0.3214	None	gnomAD-4.0.0	1.23129E-04
6641	68	T/P	151	rs768808788	0.3214	None	gnomAD-2.1.1	4.03E-06
6641	68	T/P	151	rs768808788	0.3214	None	gnomAD-4.0.0	1.5932E-06
6643	70	Q/E	153	None	0.6189	None	gnomAD-4.0.0	1.59555E-06
6643	70	Q/H	153	None	0.6189	None	gnomAD-4.0.0	1.20032E-06
6643	70	Q/R	153	rs1399714010	0.6189	None	gnomAD-2.1.1	4.06E-06
6643	70	Q/R	153	rs1399714010	0.6189	None	gnomAD-4.0.0	4.1136E-06
6644	71	Y/C	154	rs375417679	0.1064	None	gnomAD-2.1.1	4.06E-06
6644	71	Y/C	154	rs375417679	0.1064	None	gnomAD-3.1.2	6.58E-06
6644	71	Y/C	154	rs375417679	0.1064	None	gnomAD-4.0.0	1.86266E-06
6645	72	T/A	155	rs370671112	0.1763	None	gnomAD-2.1.1	2.54E-05
6645	72	T/A	155	rs370671112	0.1763	None	gnomAD-3.1.2	2.63E-05
6645	72	T/A	155	rs370671112	0.1763	None	gnomAD-4.0.0	2.36301E-05
6646	73	C/Y	156	rs575692993	0.0744	None	gnomAD-2.1.1	1.23E-05
6646	73	C/Y	156	rs575692993	0.0744	None	gnomAD-3.1.2	6.58E-06
6646	73	C/Y	156	rs575692993	0.0744	None	1000 genomes	1.99681E-04
6646	73	C/Y	156	rs575692993	0.0744	None	gnomAD-4.0.0	3.7348E-06
6647	74	H/Q	157	rs565190478	0.3586	None	gnomAD-3.1.2	6.57E-06
6647	74	H/Q	157	rs565190478	0.3586	None	1000 genomes	1.99681E-04
6647	74	H/Q	157	rs565190478	0.3586	None	gnomAD-4.0.0	6.00161E-06
6647	74	H/R	157	rs757799209	0.3586	None	gnomAD-2.1.1	4.19E-06
6647	74	H/R	157	rs757799209	0.3586	None	gnomAD-4.0.0	2.75954E-06
6648	75	V/A	158	None	0.1012	None	gnomAD-4.0.0	6.90254E-07
6648	75	V/G	158	rs752299031	0.1012	None	gnomAD-2.1.1	8.41E-06
6648	75	V/G	158	rs752299031	0.1012	None	gnomAD-4.0.0	1.38051E-06
6649	76	T/I	159	rs767035458	0.3367	None	gnomAD-2.1.1	4.2E-06
6649	76	T/I	159	rs767035458	0.3367	None	gnomAD-4.0.0	1.62667E-06
6650	77	N/S	161	rs751222632	0.1424	None	gnomAD-2.1.1	1.11E-05
6650	77	N/S	161	rs751222632	0.1424	None	gnomAD-3.1.2	1.32E-05
6650	77	N/S	161	rs751222632	0.1424	None	gnomAD-4.0.0	6.52387E-06
6650	77	N/T	161	rs751222632	0.1424	None	gnomAD-2.1.1	4.21E-06
6650	77	N/T	161	rs751222632	0.1424	None	gnomAD-4.0.0	1.62767E-06
6653	80	G/A	164	rs1446415238	0.2202	None	gnomAD-2.1.1	8.44E-06
6653	80	G/A	164	rs1446415238	0.2202	None	gnomAD-3.1.2	6.58E-06
6653	80	G/A	164	rs1446415238	0.2202	None	gnomAD-4.0.0	6.26272E-06
6653	80	G/D	164	rs1446415238	0.2202	None	gnomAD-4.0.0	1.38437E-06
6653	80	G/R	164	None	0.2202	None	gnomAD-4.0.0	1.63463E-06
6655	82	D/G	166	rs772947420	0.2856	None	gnomAD-2.1.1	2.27E-05
6655	82	D/G	166	rs772947420	0.2856	None	gnomAD-3.1.2	3.3E-05
6655	82	D/G	166	rs772947420	0.2856	None	gnomAD-4.0.0	1.32081E-05
6655	82	D/N	166	rs397517493	0.2856	None	gnomAD-2.1.1	3.77E-05
6655	82	D/N	166	rs397517493	0.2856	None	gnomAD-3.1.2	2.63E-05
6655	82	D/N	166	rs397517493	0.2856	None	gnomAD-4.0.0	6.03057E-05
6656	83	S/C	168	rs761716450	0.3151	None	gnomAD-2.1.1	8.59E-06
6656	83	S/C	168	rs761716450	0.3151	None	gnomAD-4.0.0	1.38996E-06
6656	83	S/F	168	rs761716450	0.3151	None	gnomAD-2.1.1	8.59E-06
6656	83	S/F	168	rs761716450	0.3151	None	gnomAD-4.0.0	3.47491E-06
6657	84	C/F	169	rs776748717	0.1604	None	gnomAD-2.1.1	7.6E-06
6657	84	C/F	169	rs776748717	0.1604	None	gnomAD-3.1.2	6.58E-06
6657	84	C/F	169	rs776748717	0.1604	None	gnomAD-4.0.0	2.51707E-06
6657	84	C/Y	169	None	0.1604	None	gnomAD-4.0.0	1.3917E-06
6659	86	T/A	172	rs768775530	0.1248	None	gnomAD-2.1.1	4.41E-06
6659	86	T/A	172	rs768775530	0.1248	None	gnomAD-4.0.0	3.35386E-06
6659	86	T/M	172	rs16866475	0.1248	None	gnomAD-2.1.1	4.17069E-03
6659	86	T/M	172	rs16866475	0.1248	None	gnomAD-3.1.2	1.19008E-02
6659	86	T/M	172	rs16866475	0.1248	None	1000 genomes	1.65735E-02
6659	86	T/M	172	rs16866475	0.1248	None	gnomAD-4.0.0	2.25599E-03
6660	87	M/I	173	None	0.5171	None	gnomAD-4.0.0	1.40711E-06
6660	87	M/L	173	rs780339252	0.5171	None	gnomAD-2.1.1	4.46E-06
6660	87	M/L	173	rs780339252	0.5171	None	gnomAD-4.0.0	5.06049E-06
6660	87	M/V	173	rs780339252	0.5171	None	gnomAD-2.1.1	4.46E-06
6660	87	M/V	173	rs780339252	0.5171	None	gnomAD-4.0.0	1.68683E-06
6661	88	L/S	174	rs772138264	0.1176	None	gnomAD-2.1.1	9.12E-06
6661	88	L/S	174	rs772138264	0.1176	None	gnomAD-4.0.0	8.51844E-06
6662	89	L/F	175	rs2079581150	0.5514	None	gnomAD-4.0.0	1.72006E-06

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
6574	1	P/Q	None	0.1340	gnomAD-4.0.0	1	None	0.9746	0.9873	28.8	D	None	-1.45	0.053099	-1.345	0.7958	0.7854	0.447283731627	None	0.997332	0.735	0.83602636732	1.0	0.604919612408	-4.61	0.653	0.892	0.117	None	None	1.67444E-06	0	0	0	0	None	0	0	1.67444E-06	2.97115E-06	0	0	None	N	None
6575	2	S/N	rs560328343	0.3003	gnomAD-3.1.2	2	None	0.157	0.1447	24.6	N	0.125	-0.28	0.025146	-0.209	0.5264	0.0515	0.428243941696	None	1.0	0.389	0.346768085243	0.999	0.67850124836	-1.08	0.302	0.503	0.487	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
6575	2	S/N	rs560328343	0.3003	1000 genomes	2	None	0.157	0.1447	24.6	N	0.125	-0.28	0.025146	-0.209	0.5264	0.0515	0.428243941696	None	1.0	0.389	0.346768085243	0.999	0.67850124836	-1.08	0.302	0.503	0.487	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	N	None
6575	2	S/N	rs560328343	0.3003	gnomAD-4.0.0	2	None	0.157	0.1447	24.6	N	0.125	-0.28	0.025146	-0.209	0.5264	0.0515	0.428243941696	None	1.0	0.389	0.346768085243	0.999	0.67850124836	-1.08	0.302	0.503	0.487	None	None	1.26495E-06	1.36206E-05	0	0	0	None	0	0	1.26495E-06	8.5773E-07	0	0	None	N	None
6575	2	S/T	None	0.3003	gnomAD-4.0.0	2	None	0.0787	0.0789	24.3	N	None	-0.25	0.030061	-0.236	0.3741	-0.3321	0.36004956123	None	1.0	0.435	0.276898752692	0.98	0.634200334549	-1.56	0.257	0.523	0.564	None	None	1.39967E-06	0	0	0	0	None	0	0	1.39967E-06	1.82169E-06	0	0	None	N	None
6578	5	V/L	rs2079625925	0.3761	gnomAD-3.1.2	5	None	0.1257	0.133	22.4	N	None	-0.24	0.030631	-0.391	0.2007	-0.8595	0.0834121381475	None	1.0	0.373	0.284150004643	0.002	0.542554318905	-1.62	0.197	0.072	0.197	None	None	6.58E-06	0	0	0	0	None	9.43E-05	0	6.58E-06	0	0	0	None	N	None
6578	5	V/L	rs2079625925	0.3761	gnomAD-4.0.0	5	None	0.1257	0.133	22.4	N	None	-0.24	0.030631	-0.391	0.2007	-0.8595	0.0834121381475	None	1.0	0.373	0.284150004643	0.002	0.542554318905	-1.62	0.197	0.072	0.197	None	None	6.57618E-06	0	0	0	0	None	9.42685E-05	0	6.57618E-06	0	0	0	None	N	None
6578	5	V/M	None	0.3761	gnomAD-4.0.0	5	None	0.1272	0.1316	22.6	N	None	-0.27	0.036713	-0.381	0.3192	-0.5558	0.104387959458	None	1.0	0.38	0.342631996419	0.139	0.578392505646	-1.61	0.207	0.127	0.071	None	None	1.6504E-06	0	0	0	0	None	0	0	1.6504E-06	2.9427E-06	0	0	None	N	None
6579	6	K/N	rs1578112424	0.5391	gnomAD-4.0.0	7	None	0.5285	0.5481	23.4	N	None	1.03	0.023502	-0.144	0.134	-0.9603	0.292885146693	None	1.0	0.48	0.107399877778	0.952	0.707146346569	-2.86	0.133	0.303	0.083	None	None	3.27721E-06	0	0	0	0	None	0	0	3.27721E-06	5.85566E-06	0	0	None	N	None
6580	7	P/S	rs116572520	0.2321	gnomAD-2.1.1	8	None	0.6108	0.7046	None	N	-0.651	None	None	-1.88	None	None	None	None	None	None	None	1.0	None	None	0.579	0.79	None	None	None	6.00326E-04	6.36729E-03	1.53638E-04	0	0	None	0	None	6.00326E-04	0	8.1E-06	2.96824E-04	None	N	None
6580	7	P/S	rs116572520	0.2321	gnomAD-3.1.2	8	None	0.6108	0.7046	None	N	-0.651	None	None	-1.88	None	None	None	None	None	None	None	1.0	None	None	0.579	0.79	None	None	None	1.81524E-03	6.40066E-03	4.59016E-04	0	0	None	0	0	1.81524E-03	1.47E-05	2.07211E-04	9.56938E-04	None	N	None
6580	7	P/S	rs116572520	0.2321	1000 genomes	8	None	0.6108	0.7046	None	N	-0.651	None	None	-1.88	None	None	None	None	None	None	None	1.0	None	None	0.579	0.79	None	None	None	3.39457E-03	1.29E-02	0	None	0	0	None	None	3.39457E-03	None	0	None	None	N	None
6580	7	P/S	rs116572520	0.2321	gnomAD-4.0.0	8	None	0.6108	0.7046	None	N	-0.651	None	None	-1.88	None	None	None	None	None	None	None	1.0	None	None	0.579	0.79	None	None	None	3.29817E-04	6.36513E-03	2.78581E-04	0	0	None	0	0	3.29817E-04	1.1102E-05	2.3034E-05	3.73377E-04	None	N	None
6580	7	P/T	rs116572520	0.2321	gnomAD-2.1.1	8	None	0.3593	0.4528	25.3	N	-0.624	0.35	0.030838	-1.613	0.4897	0.1308	0.48186009364	None	0.694853	0.696	0.548949488234	1.0	0.628252089024	-4.07	0.515	0.757	0.011	None	None	8.51E-06	0	6.31E-05	0	0	None	0	None	8.51E-06	0	0	0	None	N	None
6580	7	P/T	rs116572520	0.2321	gnomAD-4.0.0	8	None	0.3593	0.4528	25.3	N	-0.624	0.35	0.030838	-1.613	0.4897	0.1308	0.48186009364	None	0.694853	0.696	0.548949488234	1.0	0.628252089024	-4.07	0.515	0.757	0.011	None	None	1.38633E-06	0	4.74316E-05	0	0	None	0	0	1.38633E-06	0	0	0	None	N	None
6582	9	R/Q	rs776051087	0.8553	gnomAD-2.1.1	11	None	0.075	0.0756	None	N	-0.096	None	None	0.114	None	None	None	None	None	None	None	0.953	None	None	0.213	0.336	None	None	None	2.96E-05	8.35E-05	3E-05	0	0	None	7.17E-05	None	2.96E-05	0	1.6E-05	1.46071E-04	None	I	None
6582	9	R/Q	rs776051087	0.8553	gnomAD-3.1.2	11	None	0.075	0.0756	None	N	-0.096	None	None	0.114	None	None	None	None	None	None	None	0.953	None	None	0.213	0.336	None	None	None	5.92E-05	1.20755E-04	0	0	0	None	0	0	5.92E-05	4.41E-05	0	4.78469E-04	None	I	None
6582	9	R/Q	rs776051087	0.8553	gnomAD-4.0.0	11	None	0.075	0.0756	None	N	-0.096	None	None	0.114	None	None	None	None	None	None	None	0.953	None	None	0.213	0.336	None	None	None	2.81502E-05	1.07637E-04	1.71727E-05	3.44187E-05	0	None	1.57015E-05	0	2.81502E-05	1.96177E-05	1.0281E-04	3.23771E-05	None	I	None
6583	10	Q/R	rs1370326075	0.2980	gnomAD-4.0.0	13	None	0.139	0.1709	23.6	N	None	-0.25	0.018575	-0.128	0.2773	-0.6097	0.125504674622	None	0.624951	0.492	0.218112801441	0.135	0.597416639328	-2.33	0.219	0.205	0.233	None	None	1.61836E-06	0	0	0	2.78458E-05	None	0	0	1.61836E-06	0	0	0	None	N	None
6584	11	Q/K	rs908969278	0.7603	gnomAD-4.0.0	14	None	0.102	0.0975	None	N	None	None	None	0.01	None	None	None	None	None	None	None	0.002	None	None	0.106	0.151	None	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
6585	12	A/T	None	0.1852	gnomAD-4.0.0	16	None	0.1471	0.1352	21.4	N	None	-0.37	0.068541	-1.35	0.2726	-0.563	0.157155110211	None	0.748302	0.446	0.365892764245	0.576	0.463039159775	-2.32	0.258	0.343	0.438	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6586	13	I/T	rs896710187	0.7702	gnomAD-3.1.2	18	None	0.244	0.1637	22.2	N	None	-0.17	0.028628	-0.556	0.1989	-0.7489	0.159401868961	None	1.0	0.419	0.642625386947	0.324	0.484496474266	-2.27	0.136	0.359	0.335	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
6586	13	I/T	rs896710187	0.7702	gnomAD-4.0.0	18	None	0.244	0.1637	22.2	N	None	-0.17	0.028628	-0.556	0.1989	-0.7489	0.159401868961	None	1.0	0.419	0.642625386947	0.324	0.484496474266	-2.27	0.136	0.359	0.335	None	None	6.21717E-06	1.33837E-05	0	0	0	None	0	0	6.21717E-06	7.64588E-06	0	0	None	N	None
6586	13	I/V	None	0.7702	gnomAD-4.0.0	18	None	0.076	0.0646	20.3	N	None	-0.22	0.008267	-0.317	0.1479	-0.9657	0.0708349770375	None	1.0	0.401	0.42573502686	None	0.341026842594	-0.22	0.085	0.173	0.594	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6587	14	P/R	rs2079621657	0.4526	gnomAD-4.0.0	23	None	0.3117	0.3113	25.5	N	None	1.02	0.041578	0.001	0.2902	-0.546	0.466766929248	None	0.84745	0.448	0.330589388543	0.999	0.670112252235	-4.56	0.383	0.75	0.227	None	None	1.60498E-06	0	0	0	0	None	0	0	1.60498E-06	0	1.46011E-05	0	None	N	None
6587	14	P/T	None	0.4526	gnomAD-4.0.0	23	None	0.2025	0.2007	23.5	N	None	1.03	0.033386	-0.647	0.2488	-0.6902	0.4776242743	None	0.701553	0.426	0.263612267334	0.999	0.643318533897	-3.74	0.332	0.709	0.257	None	None	6.86684E-07	0	0	0	0	None	0	0	6.86684E-07	9.01634E-07	0	0	None	N	None
6588	15	D/H	None	0.7999	gnomAD-4.0.0	24	None	0.3015	0.2494	22.8	N	None	-0.32	0.035138	-0.035	0.4832	-0.0741	0.459767181995	None	1.0	0.61	0.39843156188	0.988	0.474764883518	-3.58	0.398	0.593	0.076	None	None	6.85357E-06	0	0	0	0	None	0	0	6.85357E-06	9.00526E-06	0	0	None	N	None
6588	15	D/N	None	0.7999	gnomAD-4.0.0	24	None	0.0958	0.0802	21.4	N	None	-0.27	0.030668	0.294	0.1849	-0.8533	0.0917990224253	None	1.0	0.456	0.233785782151	0.061	0.451193630695	-2.52	0.224	0.301	0.396	None	None	6.85357E-07	0	0	0	0	None	0	0	6.85357E-07	9.00526E-07	0	0	None	N	None
6589	16	S/C	rs1206769574	0.2475	gnomAD-2.1.1	25	None	0.2076	0.1936	24.3	N	-0.79	0.87	0.051098	-0.496	0.3095	-0.4247	0.416609245042	None	1.0	0.497	0.321108458156	0.999	0.516952633858	-3.11	0.332	0.345	0.117	None	None	4.04E-06	6.48E-05	0	0	0	None	0	None	4.04E-06	0	0	0	None	N	None
6589	16	S/C	rs1206769574	0.2475	gnomAD-4.0.0	25	None	0.2076	0.1936	24.3	N	-0.79	0.87	0.051098	-0.496	0.3095	-0.4247	0.416609245042	None	1.0	0.497	0.321108458156	0.999	0.516952633858	-3.11	0.332	0.345	0.117	None	None	6.84978E-07	2.99365E-05	0	0	0	None	0	0	6.84978E-07	0	0	0	None	N	None
6589	16	S/Y	None	0.2475	gnomAD-4.0.0	25	None	0.338	0.2768	23.9	N	None	0.88	0.052111	-0.792	0.3041	-0.4349	0.464197403423	None	0.565561	0.48	0.504907739247	0.996	0.565864920616	-3.47	0.386	0.428	0.031	None	None	6.84978E-07	0	0	0	0	None	0	0	6.84978E-07	9.00182E-07	0	0	None	N	None
6590	17	T/A	rs1296238597	0.4290	gnomAD-2.1.1	26	None	0.0708	0.0686	20.4	N	-0.825	0.9	0.012298	-0.64	0.0769	-1.0476	0.0850969924029	None	1.0	0.384	0.0806252709748	0.005	0.415122210979	-2.72	0.066	0.099	0.293	None	None	4.04E-06	0	0	0	0	None	3.29E-05	None	4.04E-06	0	0	0	None	N	None
6590	17	T/A	rs1296238597	0.4290	gnomAD-4.0.0	26	None	0.0708	0.0686	20.4	N	-0.825	0.9	0.012298	-0.64	0.0769	-1.0476	0.0850969924029	None	1.0	0.384	0.0806252709748	0.005	0.415122210979	-2.72	0.066	0.099	0.293	None	None	1.59523E-06	0	0	0	0	None	0	0	1.59523E-06	0	1.4403E-05	0	None	N	None
6590	17	T/I	rs760473000	0.4290	gnomAD-2.1.1	26	None	0.1437	0.1475	None	N	-0.126	None	None	-0.278	None	None	None	None	None	None	None	0.669	None	None	0.187	0.355	None	None	None	1.62E-05	0	0	0	0	None	0	None	1.62E-05	0	3.57E-05	0	None	N	None
6590	17	T/I	rs760473000	0.4290	gnomAD-4.0.0	26	None	0.1437	0.1475	None	N	-0.126	None	None	-0.278	None	None	None	None	None	None	None	0.669	None	None	0.187	0.355	None	None	None	4.79518E-06	0	0	0	0	None	0	0	4.79518E-06	6.30151E-06	0	0	None	N	None
6591	18	V/G	rs2079619288	0.1815	gnomAD-3.1.2	28	None	0.5815	0.635	24.7	N	None	0.68	0.033485	-2.167	0.3826	-0.0107	0.452165899345	None	0.999986	0.539	0.795264024752	0.997	0.450706124306	-3.99	0.487	0.757	0.511	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07125E-04	0	None	N	None
6591	18	V/G	rs2079619288	0.1815	gnomAD-4.0.0	28	None	0.5815	0.635	24.7	N	None	0.68	0.033485	-2.167	0.3826	-0.0107	0.452165899345	None	0.999986	0.539	0.795264024752	0.997	0.450706124306	-3.99	0.487	0.757	0.511	None	None	2.56654E-06	0	0	0	0	None	0	0	2.56654E-06	0	2.69092E-05	0	None	N	None
6595	22	A/T	rs1305423472	0.1049	gnomAD-2.1.1	33	None	0.112	0.123	22.9	N	-1.364	0.92	0.047655	-0.943	0.1524	-0.892	0.207818169212	None	1.0	0.644	0.273503213844	0.811	0.453708350658	-2.18	0.254	0.702	0.587	None	None	7.16E-06	0	0	0	5.13E-05	None	0	None	7.16E-06	4.01E-05	0	0	None	N	None
6595	22	A/T	rs1305423472	0.1049	gnomAD-3.1.2	33	None	0.112	0.123	22.9	N	-1.364	0.92	0.047655	-0.943	0.1524	-0.892	0.207818169212	None	1.0	0.644	0.273503213844	0.811	0.453708350658	-2.18	0.254	0.702	0.587	None	None	6.58E-06	0	0	0	0	None	9.43E-05	0	6.58E-06	0	0	0	None	N	None
6595	22	A/T	rs1305423472	0.1049	gnomAD-4.0.0	33	None	0.112	0.123	22.9	N	-1.364	0.92	0.047655	-0.943	0.1524	-0.892	0.207818169212	None	1.0	0.644	0.273503213844	0.811	0.453708350658	-2.18	0.254	0.702	0.587	None	None	2.48042E-06	0	0	0	4.45891E-05	None	1.56284E-05	0	2.48042E-06	8.48043E-07	0	0	None	N	None
6596	23	I/M	rs2079617659	0.2973	gnomAD-4.0.0	34	None	0.0816	0.0815	20.4	D	None	-0.24	0.033928	-0.627	0.1864	-0.7933	0.119898914796	None	1.0	0.403	0.231873229951	0.108	0.312002569437	-0.93	0.059	0.421	0.122	None	None	1.59302E-06	0	0	0	0	None	0	0	1.59302E-06	0	1.43559E-05	0	None	N	None
6596	23	I/T	None	0.2973	gnomAD-4.0.0	34	None	0.0958	0.0944	22.4	N	None	-0.05	0.055764	-1.33	0.1298	-0.9247	0.105969166871	None	1.0	0.433	0.541285430251	None	0.31095790863	-1.27	0.111	0.153	0.487	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6596	23	I/V	rs369108292	0.2973	gnomAD-2.1.1	34	None	0.0575	0.0555	None	N	-0.76	None	None	-0.949	None	None	None	None	None	None	None	None	None	None	0.08	0.085	None	None	None	8.06E-06	6.47E-05	2.9E-05	0	0	None	0	None	8.06E-06	0	0	0	None	N	None
6596	23	I/V	rs369108292	0.2973	gnomAD-3.1.2	34	None	0.0575	0.0555	None	N	-0.76	None	None	-0.949	None	None	None	None	None	None	None	None	None	None	0.08	0.085	None	None	None	2.63E-05	9.65E-05	0	0	0	None	0	0	2.63E-05	0	0	0	None	N	None
6596	23	I/V	rs369108292	0.2973	gnomAD-4.0.0	34	None	0.0575	0.0555	None	N	-0.76	None	None	-0.949	None	None	None	None	None	None	None	None	None	None	0.08	0.085	None	None	None	4.34001E-06	8.01196E-05	1.66767E-05	0	0	None	0	0	4.34001E-06	0	0	0	None	N	None
6597	24	L/I	None	0.1436	gnomAD-4.0.0	35	None	0.1075	0.114	19.76	N	None	None	0.009734	-0.648	0.0753	-0.9498	0.152889730461	None	1.0	0.381	0.39843156188	0.64	0.481861531734	-1.07	0.141	0.714	0.54	None	None	6.00161E-06	0	0	0	0	None	0	0	6.00161E-06	6.56251E-06	0	0	None	N	None
6597	24	L/P	rs745676008	0.1436	gnomAD-2.1.1	35	None	0.8883	0.8794	27.6	N	-1.095	-0.31	0.041394	-1.184	0.3083	-0.3608	0.533616575574	None	0.999961	0.722	0.690133245405	0.995	0.570571601391	-4.1	0.572	0.83	0.037	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.9E-06	0	None	N	None
6597	24	L/P	rs745676008	0.1436	gnomAD-4.0.0	35	None	0.8883	0.8794	27.6	N	-1.095	-0.31	0.041394	-1.184	0.3083	-0.3608	0.533616575574	None	0.999961	0.722	0.690133245405	0.995	0.570571601391	-4.1	0.572	0.83	0.037	None	None	2.6012E-05	0	0	0	0	None	0	0	2.6012E-05	3.41923E-05	0	0	None	N	None
6599	26	G/E	None	0.1699	gnomAD-4.0.0	40	None	0.9878	0.995	24.5	D	None	-1.14	0.090915	-0.621	0.7733	0.7533	0.526218639335	None	0.999825	0.89	0.705268275649	1.0	0.753137111664	-3.71	0.723	0.811	0.443	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	I	None
6600	27	T/A	rs530353051	0.2759	gnomAD-2.1.1	41	None	0.1644	0.2071	25.7	N	-0.423	-0.24	0.013236	-0.546	0.4679	-0.0436	0.451143628614	None	0.967049	0.449	0.424194796918	0.993	0.536290824413	-2.53	0.349	0.587	0.486	None	None	2.82E-05	0	1.73974E-04	0	0	None	0	None	2.82E-05	0	8.89E-06	0	None	I	None
6600	27	T/A	rs530353051	0.2759	gnomAD-3.1.2	41	None	0.1644	0.2071	25.7	N	-0.423	-0.24	0.013236	-0.546	0.4679	-0.0436	0.451143628614	None	0.967049	0.449	0.424194796918	0.993	0.536290824413	-2.53	0.349	0.587	0.486	None	None	1.97E-05	0	6.55E-05	2.88018E-04	0	None	0	0	1.97E-05	1.47E-05	0	0	None	I	None
6600	27	T/A	rs530353051	0.2759	1000 genomes	41	None	0.1644	0.2071	25.7	N	-0.423	-0.24	0.013236	-0.546	0.4679	-0.0436	0.451143628614	None	0.967049	0.449	0.424194796918	0.993	0.536290824413	-2.53	0.349	0.587	0.486	None	None	1.99681E-04	0	0	None	0	1E-03	None	None	1.99681E-04	None	0	None	None	I	None
6600	27	T/A	rs530353051	0.2759	gnomAD-4.0.0	41	None	0.1644	0.2071	25.7	N	-0.423	-0.24	0.013236	-0.546	0.4679	-0.0436	0.451143628614	None	0.967049	0.449	0.424194796918	0.993	0.536290824413	-2.53	0.349	0.587	0.486	None	None	1.6664E-05	0	1.69497E-04	4.09433E-05	0	None	0	0	1.6664E-05	4.79058E-06	0	0	None	I	None
6600	27	T/I	rs1355564295	0.2759	gnomAD-2.1.1	41	None	0.4029	0.5145	27.3	N	0.119	-0.32	0.021302	-0.086	0.4865	-0.0855	0.480749730577	None	0.998287	0.443	0.528614029291	1.0	0.641561865807	-3.33	0.42	0.765	0.118	None	None	4.02E-06	0	0	0	5.57E-05	None	0	None	4.02E-06	0	0	0	None	I	None
6600	27	T/I	rs1355564295	0.2759	gnomAD-4.0.0	41	None	0.4029	0.5145	27.3	N	0.119	-0.32	0.021302	-0.086	0.4865	-0.0855	0.480749730577	None	0.998287	0.443	0.528614029291	1.0	0.641561865807	-3.33	0.42	0.765	0.118	None	None	2.40065E-06	0	0	0	2.75482E-04	None	0	0	2.40065E-06	0	0	3.66327E-05	None	I	None
6601	28	P/L	None	0.4870	gnomAD-4.0.0	42	None	0.1075	0.1099	24.9	D	None	-0.85	0.050079	-0.337	0.6066	0.4718	0.317999660702	None	0.99956	0.816	0.551384154659	0.942	0.613452315331	-5.17	0.725	0.619	0.196	None	None	6.84477E-07	0	0	0	0	None	0	0	6.84477E-07	0	0	1.65733E-05	None	I	None
6601	28	P/Q	rs1578111426	0.4870	gnomAD-4.0.0	42	None	0.1391	0.1561	23.1	D	None	-0.81	0.059278	-0.519	0.5107	0.0038	0.102746138045	None	0.823517	0.801	0.398133443147	0.126	0.559193611145	-4.28	0.638	0.311	0.175	None	None	6.84477E-07	0	0	0	0	None	0	0	6.84477E-07	8.99771E-07	0	0	None	I	None
6601	28	P/S	rs1175980116	0.4870	gnomAD-2.1.1	42	None	0.1169	0.1328	22.2	D	-0.379	-0.79	0.058047	-0.679	0.5739	0.1965	0.268560376746	None	0.79295	0.779	0.490144168196	0.698	0.551925420761	-4.16	0.602	0.502	0.16	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.89E-06	0	None	I	None
6601	28	P/S	rs1175980116	0.4870	gnomAD-3.1.2	42	None	0.1169	0.1328	22.2	D	-0.379	-0.79	0.058047	-0.679	0.5739	0.1965	0.268560376746	None	0.79295	0.779	0.490144168196	0.698	0.551925420761	-4.16	0.602	0.502	0.16	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	I	None
6601	28	P/S	rs1175980116	0.4870	gnomAD-4.0.0	42	None	0.1169	0.1328	22.2	D	-0.379	-0.79	0.058047	-0.679	0.5739	0.1965	0.268560376746	None	0.79295	0.779	0.490144168196	0.698	0.551925420761	-4.16	0.602	0.502	0.16	None	None	6.81922E-06	2.67123E-05	0	0	0	None	0	0	6.81922E-06	5.93521E-06	0	3.20349E-05	None	I	None
6602	29	P/Q	rs749229040	0.7534	gnomAD-2.1.1	43	None	0.3278	0.458	26.1	D	-0.123	-0.15	0.01787	-0.532	0.4294	-0.2251	0.449666334578	None	0.99957	0.55	0.492267288202	1.0	0.57088971138	-4.41	0.448	0.635	0.137	None	None	4.02E-06	0	0	0	5.57E-05	None	0	None	4.02E-06	0	0	0	None	I	None
6602	29	P/Q	rs749229040	0.7534	gnomAD-4.0.0	43	None	0.3278	0.458	26.1	D	-0.123	-0.15	0.01787	-0.532	0.4294	-0.2251	0.449666334578	None	0.99957	0.55	0.492267288202	1.0	0.57088971138	-4.41	0.448	0.635	0.137	None	None	6.3705E-06	0	0	0	8.3227E-05	None	0	0	6.3705E-06	2.86113E-06	0	0	None	I	None
6602	29	P/R	rs749229040	0.7534	gnomAD-3.1.2	43	None	0.3608	0.4924	26.4	N	None	-0.25	0.029387	-0.109	0.5181	0.0064	0.4773412541	None	0.999775	0.604	0.571380689955	1.0	0.632069408894	-4.98	0.507	0.664	0.043	None	None	1.32E-05	4.83E-05	0	0	0	None	0	0	1.32E-05	0	0	0	None	I	None
6602	29	P/R	rs749229040	0.7534	gnomAD-4.0.0	43	None	0.3608	0.4924	26.4	N	None	-0.25	0.029387	-0.109	0.5181	0.0064	0.4773412541	None	0.999775	0.604	0.571380689955	1.0	0.632069408894	-4.98	0.507	0.664	0.043	None	None	1.31506E-05	4.82719E-05	0	0	0	None	0	0	1.31506E-05	0	0	0	None	I	None
6602	29	P/S	None	0.7534	gnomAD-4.0.0	43	None	0.2395	0.3349	24.2	N	None	-0.22	0.029367	-0.668	0.5495	0.1104	0.466031226403	None	0.9995	0.525	0.527908583987	1.0	0.568621456623	-4.16	0.475	0.671	0.149	None	None	1.5926E-06	0	0	0	0	None	0	0	1.5926E-06	2.8611E-06	0	0	None	I	None
6605	32	I/M	None	0.2570	gnomAD-4.0.0	46	None	0.1223	0.1178	21.8	D	None	-0.64	0.02831	-0.567	0.39	-0.222	0.253525898805	None	1.0	0.655	0.498830998431	0.876	0.490306794643	-1.81	0.447	0.595	0.028	None	None	1.20034E-06	0	0	0	0	None	0	0	1.20034E-06	1.31252E-06	0	0	None	I	None
6607	34	W/R	None	0.1168	gnomAD-4.0.0	48	None	0.9982	0.998	29.7	D	None	-3.97	0.544408	-2.25	0.9668	1.0869	0.61613149071	None	0.99478	0.915	0.939463572141	1.0	0.827631175518	-9.1	0.919	0.871	0.013	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6608	35	F/C	None	0.1560	gnomAD-4.0.0	49	None	0.2443	0.3589	28.7	N	None	0.81	0.045767	-1.569	0.37	-0.0211	0.426590605435	None	1.0	0.669	0.743636555992	0.958	0.590441226959	-2.67	0.38	0.702	0.168	None	None	3.18464E-06	0	0	0	0	None	0	0	3.18464E-06	5.72145E-06	0	0	None	N	None
6608	35	F/L	None	0.1560	gnomAD-4.0.0	49	None	0.4285	0.6109	22.8	N	None	1.0	0.027819	-1.708	0.0908	-1.0204	0.098757273486	None	1.0	0.621	0.254761474806	None	0.586310982704	-1.24	0.127	0.198	0.745	None	None	6.84402E-07	0	0	0	2.52016E-05	None	0	0	6.84402E-07	0	0	0	None	N	None
6609	36	K/N	rs781410754	0.1465	gnomAD-2.1.1	50	None	0.9102	0.9217	23.1	D	-0.762	0.56	0.022094	-0.877	0.4091	-0.2389	0.500868633848	None	1.0	0.767	0.190952846119	1.0	0.564952373505	-3.32	0.464	0.713	0.018	None	None	6.84E-05	0	0	0	8.90571E-04	None	0	None	6.84E-05	0	0	1.65837E-04	None	N	None
6609	36	K/N	rs781410754	0.1465	gnomAD-3.1.2	50	None	0.9102	0.9217	23.1	D	-0.762	0.56	0.022094	-0.877	0.4091	-0.2389	0.500868633848	None	1.0	0.767	0.190952846119	1.0	0.564952373505	-3.32	0.464	0.713	0.018	None	None	2.63E-05	0	0	0	7.72798E-04	None	0	0	2.63E-05	0	0	0	None	N	None
6609	36	K/N	rs781410754	0.1465	gnomAD-4.0.0	50	None	0.9102	0.9217	23.1	D	-0.762	0.56	0.022094	-0.877	0.4091	-0.2389	0.500868633848	None	1.0	0.767	0.190952846119	1.0	0.564952373505	-3.32	0.464	0.713	0.018	None	None	1.3688E-06	0	0	0	0	None	0	0	1.3688E-06	1.79942E-06	0	0	None	N	None
6609	36	K/R	rs756188488	0.1465	gnomAD-2.1.1	50	None	0.0912	0.1009	25.1	N	-0.515	0.76	0.010291	-0.713	0.2632	-0.5821	0.423955509883	None	0.790125	0.776	0.249502417897	1.0	0.478450894356	-1.67	0.304	0.601	0.424	None	None	1.61E-05	0	1.15922E-04	0	0	None	0	None	1.61E-05	0	0	0	None	N	None
6609	36	K/R	rs756188488	0.1465	gnomAD-3.1.2	50	None	0.0912	0.1009	25.1	N	-0.515	0.76	0.010291	-0.713	0.2632	-0.5821	0.423955509883	None	0.790125	0.776	0.249502417897	1.0	0.478450894356	-1.67	0.304	0.601	0.424	None	None	1.31E-05	0	1.31079E-04	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
6609	36	K/R	rs756188488	0.1465	gnomAD-4.0.0	50	None	0.0912	0.1009	25.1	N	-0.515	0.76	0.010291	-0.713	0.2632	-0.5821	0.423955509883	None	0.790125	0.776	0.249502417897	1.0	0.478450894356	-1.67	0.304	0.601	0.424	None	None	7.69059E-06	0	1.01716E-04	0	0	None	0	0	7.69059E-06	0	0	0	None	N	None
6610	37	D/E	None	0.4218	gnomAD-4.0.0	51	None	0.165	0.1973	22.1	N	None	0.78	0.005741	-0.526	0.0717	-0.9897	0.0787792494489	None	1.0	0.745	0.134241683229	0.002	0.493135690689	-1.57	0.108	0.142	0.386	None	None	1.59229E-06	0	0	0	2.77377E-05	None	0	0	1.59229E-06	0	0	0	None	N	None
6610	37	D/G	None	0.4218	gnomAD-4.0.0	51	None	0.1067	0.1168	25.4	N	None	0.86	0.016819	-0.914	0.1271	-0.8829	0.338584393969	None	0.970132	0.723	0.185906805712	0.918	0.479400038719	-2.93	0.327	0.536	0.118	None	None	6.84404E-07	0	0	0	0	None	0	0	6.84404E-07	8.99716E-07	0	0	None	N	None
6610	37	D/H	None	0.4218	gnomAD-4.0.0	51	None	0.3915	0.4496	23.7	N	None	0.69	0.043129	-0.373	0.2559	-0.5775	0.11874784437	None	0.946841	0.739	0.20549828249	0.131	0.538749217987	-3.56	0.454	0.342	0.01	None	None	3.18461E-06	0	0	0	0	None	0	0	3.18461E-06	0	2.86681E-05	0	None	N	None
6610	37	D/V	rs755182614	0.4218	gnomAD-2.1.1	51	None	0.3899	0.4602	27.5	N	0.157	0.68	0.034739	-0.128	0.2709	-0.4409	0.403073445309	None	0.999997	0.727	0.567605623258	0.986	0.469737648964	-4.74	0.521	0.617	0.003	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
6610	37	D/V	rs755182614	0.4218	gnomAD-4.0.0	51	None	0.3899	0.4602	27.5	N	0.157	0.68	0.034739	-0.128	0.2709	-0.4409	0.403073445309	None	0.999997	0.727	0.567605623258	0.986	0.469737648964	-4.74	0.521	0.617	0.003	None	None	6.84404E-07	0	0	0	0	None	0	0	6.84404E-07	0	1.15977E-05	0	None	N	None
6611	38	D/G	None	0.9304	gnomAD-4.0.0	52	None	0.0875	0.0898	22.9	N	None	1.45	0.020099	-0.376	0.0495	-1.0894	0.115012441237	None	0.885744	0.626	0.0762999501168	0.006	0.493668138981	-3.43	0.146	0.315	0.621	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
6611	38	D/N	None	0.9304	gnomAD-4.0.0	52	None	0.0672	0.0721	22.0	N	None	1.01	0.047964	-0.043	0.1566	-0.9079	0.248531968292	None	0.986311	0.605	0.124217242631	0.864	0.52796626091	-2.55	0.236	0.462	0.431	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
6612	39	V/A	None	0.5794	gnomAD-4.0.0	55	None	0.0936	0.1036	22.8	N	None	-0.16	0.014334	-0.869	0.1824	-0.8529	0.117002942572	None	1.0	0.45	0.359151904892	0.047	0.333811223507	-1.58	0.085	0.177	0.797	None	None	6.84395E-07	0	0	0	0	None	0	0	6.84395E-07	8.99703E-07	0	0	None	N	None
6612	39	V/E	rs751909040	0.5794	gnomAD-2.1.1	55	None	0.131	0.1324	23.1	N	-0.254	-0.09	0.034079	-0.462	0.1822	-0.7826	0.182604631048	None	1.0	0.575	0.63942624558	0.351	0.321507275105	-2.56	0.213	0.399	1.0	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
6612	39	V/E	rs751909040	0.5794	gnomAD-4.0.0	55	None	0.131	0.1324	23.1	N	-0.254	-0.09	0.034079	-0.462	0.1822	-0.7826	0.182604631048	None	1.0	0.575	0.63942624558	0.351	0.321507275105	-2.56	0.213	0.399	1.0	None	None	1.36879E-06	0	0	0	0	None	0	0	1.36879E-06	0	1.15974E-05	1.65722E-05	None	N	None
6612	39	V/M	None	0.5794	gnomAD-4.0.0	55	None	0.078	0.0821	21.3	N	None	-0.26	0.012686	-0.403	0.1951	-0.8492	0.0920125637345	None	1.0	0.376	0.216624796971	0.017	0.335412561893	-1.25	0.048	0.171	0.133	None	None	1.59229E-06	0	0	0	0	None	0	0	1.59229E-06	2.86069E-06	0	0	None	N	None
6614	41	L/I	rs758885175	0.2294	gnomAD-2.1.1	58	None	0.0876	0.1004	23.5	N	-0.538	-0.42	0.039167	-0.685	0.2633	-0.5406	0.209375843923	None	1.0	0.609	0.581442141994	0.884	0.580317258835	-1.29	0.274	0.364	0.787	None	None	4.02E-06	0	0	0	0	None	3.27E-05	None	4.02E-06	0	0	0	None	N	None
6614	41	L/I	rs758885175	0.2294	gnomAD-4.0.0	58	None	0.0876	0.1004	23.5	N	-0.538	-0.42	0.039167	-0.685	0.2633	-0.5406	0.209375843923	None	1.0	0.609	0.581442141994	0.884	0.580317258835	-1.29	0.274	0.364	0.787	None	None	1.59225E-06	0	0	0	0	None	0	0	1.59225E-06	0	1.43328E-05	0	None	N	None
6615	42	V/L	None	0.8030	gnomAD-4.0.0	59	None	0.096	0.0954	17.81	N	None	-0.22	0.031691	-0.244	0.1764	-0.8401	0.0822650963644	None	0.999955	0.409	0.443388199986	None	0.32372045517	-1.16	0.066	0.093	0.335	None	None	8.21269E-06	0	0	0	0	None	0	0	8.21269E-06	8.99698E-06	0	3.31422E-05	None	I	None
6617	44	G/D	rs371847228	0.3795	gnomAD-2.1.1	73	None	0.3446	0.3463	None	N	0.166	None	None	-0.323	None	None	None	None	None	None	None	1.0	None	None	0.43	0.684	None	None	None	6.78E-05	6.20347E-04	8.49E-05	0	0	None	0	None	6.78E-05	0	0	1.40449E-04	None	N	None
6617	44	G/D	rs371847228	0.3795	gnomAD-3.1.2	73	None	0.3446	0.3463	None	N	0.166	None	None	-0.323	None	None	None	None	None	None	None	1.0	None	None	0.43	0.684	None	None	None	2.17025E-04	7.48395E-04	6.56E-05	0	0	None	0	0	2.17025E-04	1.47E-05	0	0	None	N	None
6617	44	G/D	rs371847228	0.3795	gnomAD-4.0.0	73	None	0.3446	0.3463	None	N	0.166	None	None	-0.323	None	None	None	None	None	None	None	1.0	None	None	0.43	0.684	None	None	None	3.53334E-05	6.54608E-04	8.33722E-05	0	0	None	0	0	3.53334E-05	8.47836E-07	0	3.20318E-05	None	N	None
6618	45	P/A	None	0.9080	gnomAD-4.0.0	102	None	0.0926	0.0977	22.1	N	None	1.0	0.016252	-0.348	0.1159	-0.9806	0.191897163626	None	1.0	0.476	0.178374595973	0.811	0.533670127392	-4.18	0.119	0.403	0.756	None	None	1.36878E-06	0	0	0	0	None	0	0	1.36878E-06	0	2.31949E-05	0	None	N	None
6618	45	P/L	None	0.9080	gnomAD-4.0.0	102	None	0.1489	0.1616	23.7	N	None	0.93	0.038631	-0.311	0.1659	-0.8965	0.316564442422	None	0.996484	0.478	0.512595481341	0.938	0.603144407272	-5.63	0.291	0.491	0.356	None	None	3.18465E-06	5.66765E-05	0	0	0	None	0	0	3.18465E-06	2.86074E-06	0	0	None	N	None
6618	45	P/S	rs1234787097	0.9080	gnomAD-2.1.1	102	None	0.1123	0.1187	22.5	N	-0.242	1.07	0.017077	-0.528	0.1077	-1.0091	0.235098826708	None	1.0	0.42	0.167679373172	0.811	0.548611521721	-3.88	0.115	0.357	0.691	None	None	4.02E-06	0	0	0	5.56E-05	None	0	None	4.02E-06	0	0	0	None	N	None
6618	45	P/S	rs1234787097	0.9080	gnomAD-4.0.0	102	None	0.1123	0.1187	22.5	N	-0.242	1.07	0.017077	-0.528	0.1077	-1.0091	0.235098826708	None	1.0	0.42	0.167679373172	0.811	0.548611521721	-3.88	0.115	0.357	0.691	None	None	6.84391E-07	0	0	0	2.52016E-05	None	0	0	6.84391E-07	0	0	0	None	N	None
6619	46	K/E	rs1060500450	0.8141	gnomAD-2.1.1	115	None	0.1078	0.148	22.2	N	0.559	0.9	0.011788	0.257	0.1237	-0.9897	0.133527597129	None	1.0	0.597	0.20549828249	0.052	0.397936880589	-2.07	0.17	0.279	0.23	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
6619	46	K/E	rs1060500450	0.8141	gnomAD-3.1.2	115	None	0.1078	0.148	22.2	N	0.559	0.9	0.011788	0.257	0.1237	-0.9897	0.133527597129	None	1.0	0.597	0.20549828249	0.052	0.397936880589	-2.07	0.17	0.279	0.23	None	None	1.97E-05	0	0	0	0	None	0	0	1.97E-05	4.41E-05	0	0	None	N	None
6619	46	K/E	rs1060500450	0.8141	gnomAD-4.0.0	115	None	0.1078	0.148	22.2	N	0.559	0.9	0.011788	0.257	0.1237	-0.9897	0.133527597129	None	1.0	0.597	0.20549828249	0.052	0.397936880589	-2.07	0.17	0.279	0.23	None	None	1.1536E-05	0	0	0	0	None	0	0	1.1536E-05	2.15532E-05	0	0	None	N	None
6619	46	K/T	rs368720026	0.8141	gnomAD-2.1.1	115	None	0.1028	0.1067	None	N	-0.275	None	None	-0.058	None	None	None	None	None	None	None	None	None	None	0.105	0.109	None	None	None	8.04E-06	6.47E-05	0	0	0	None	0	None	8.04E-06	0	0	1.65728E-04	None	N	None
6619	46	K/T	rs368720026	0.8141	gnomAD-3.1.2	115	None	0.1028	0.1067	None	N	-0.275	None	None	-0.058	None	None	None	None	None	None	None	None	None	None	0.105	0.109	None	None	None	5.92E-05	1.93087E-04	6.56E-05	0	0	None	0	0	5.92E-05	0	0	0	None	N	None
6619	46	K/T	rs368720026	0.8141	gnomAD-4.0.0	115	None	0.1028	0.1067	None	N	-0.275	None	None	-0.058	None	None	None	None	None	None	None	None	None	None	0.105	0.109	None	None	None	1.79463E-05	1.69279E-04	5.08613E-05	0	0	None	0	0	1.79463E-05	2.39479E-06	0	0	None	N	None
6620	47	C/F	None	0.1632	gnomAD-4.0.0	121	None	0.2311	0.2109	22.5	N	None	-0.1	0.043398	-1.043	0.2189	-0.6562	0.229955376023	None	0.918999	0.553	0.774720988625	0.565	0.777933835983	-5.4	0.295	0.7	0.718	None	None	6.84404E-07	0	0	0	0	None	0	0	6.84404E-07	8.99711E-07	0	0	None	N	None
6620	47	C/R	rs1470771648	0.1632	gnomAD-3.1.2	121	None	0.6738	0.6413	23.9	N	None	-0.22	0.039449	-1.169	0.3408	-0.352	0.480496331412	None	0.999997	0.727	0.841100326879	0.949	0.828308343887	-6.49	0.581	0.801	0.302	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
6620	47	C/R	rs1470771648	0.1632	gnomAD-4.0.0	121	None	0.6738	0.6413	23.9	N	None	-0.22	0.039449	-1.169	0.3408	-0.352	0.480496331412	None	0.999997	0.727	0.841100326879	0.949	0.828308343887	-6.49	0.581	0.801	0.302	None	None	6.5735E-06	2.41289E-05	0	0	0	None	0	0	6.5735E-06	0	0	0	None	N	None
6620	47	C/Y	rs935626596	0.1632	gnomAD-2.1.1	121	None	0.215	0.215	22.3	N	-1.366	-0.06	0.030145	-1.116	0.1432	-0.9391	0.148319375982	None	0.813032	0.501	0.592799456133	0.003	0.836333811283	-5.0	0.285	0.453	1.0	None	None	1.61E-05	0	0	0	1.66945E-04	None	0	None	1.61E-05	0	8.88E-06	0	None	N	None
6620	47	C/Y	rs935626596	0.1632	gnomAD-4.0.0	121	None	0.215	0.215	22.3	N	-1.366	-0.06	0.030145	-1.116	0.1432	-0.9391	0.148319375982	None	0.813032	0.501	0.592799456133	0.003	0.836333811283	-5.0	0.285	0.453	1.0	None	None	6.15963E-06	0	0	0	2.52016E-05	None	0	0	6.15963E-06	5.39827E-06	2.31954E-05	0	None	N	None
6621	48	F/L	rs760276555	0.4564	gnomAD-2.1.1	122	None	0.8662	0.8196	22.6	N	-1.128	-0.16	0.023043	-0.8	0.1582	-0.9274	0.102898758398	None	1.0	0.408	0.313518423057	0.026	0.646626770496	-3.28	0.187	0.165	0.31	None	None	8.04E-06	0	0	0	5.57E-05	None	0	None	8.04E-06	0	8.88E-06	0	None	N	None
6621	48	F/L	rs760276555	0.4564	gnomAD-4.0.0	122	None	0.8662	0.8196	22.6	N	-1.128	-0.16	0.023043	-0.8	0.1582	-0.9274	0.102898758398	None	1.0	0.408	0.313518423057	0.026	0.646626770496	-3.28	0.187	0.165	0.31	None	None	4.77693E-06	0	0	0	2.77393E-05	None	0	0	4.77693E-06	2.86067E-06	0	3.0259E-05	None	N	None
6622	49	I/F	rs775092361	0.1958	gnomAD-2.1.1	123	None	0.1398	0.106	22.7	N	-1.044	-0.38	0.045974	-0.993	0.2808	-0.5643	0.135862692089	None	1.0	0.486	0.292423486923	0.006	0.49662309885	-2.43	0.322	0.218	0.121	None	None	4.02E-06	0	0	0	5.56E-05	None	0	None	4.02E-06	0	0	0	None	I	None
6622	49	I/N	rs1413452032	0.1958	gnomAD-2.1.1	123	None	0.5268	0.4221	22.9	N	-1.391	-0.45	0.065187	-1.248	0.4134	-0.0218	0.347945770222	None	1.0	0.625	0.822951172334	0.927	0.568098425865	-4.27	0.544	0.626	0.002	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.87E-06	0	None	I	None
6622	49	I/N	rs1413452032	0.1958	gnomAD-4.0.0	123	None	0.5268	0.4221	22.9	N	-1.391	-0.45	0.065187	-1.248	0.4134	-0.0218	0.347945770222	None	1.0	0.625	0.822951172334	0.927	0.568098425865	-4.27	0.544	0.626	0.002	None	None	1.59231E-06	0	0	0	0	None	0	0	1.59231E-06	2.86072E-06	0	0	None	I	None
6624	51	L/F	rs78279193	0.3540	gnomAD-4.0.0	127	None	0.1155	0.105	19.81	N	-0.934	-0.22	0.020427	-0.603	0.215	-0.8011	0.130504258297	None	1.0	0.402	0.337868961071	0.723	0.529543042183	-1.93	0.196	0.609	0.166	None	None	3.18506E-06	0	0	0	0	None	1.8843E-05	0	3.18506E-06	0	0	3.02682E-05	None	N	None
6626	53	G/E	rs1362220931	0.5162	gnomAD-2.1.1	131	None	0.2259	0.218	25.3	N	-0.243	0.83	0.031804	-0.361	0.2242	-0.6951	0.518184149625	None	0.858019	0.728	0.32714864917	0.999	0.689488530159	-4.39	0.315	0.688	0.019	None	None	4.02E-06	0	0	0	0	None	0	None	4.02E-06	0	8.88E-06	0	None	N	None
6626	53	G/R	rs770749098	0.5162	gnomAD-2.1.1	131	None	0.4217	0.4343	25.2	N	-0.671	0.76	0.033537	-0.35	0.3333	-0.4358	0.497842640141	None	0.996612	0.789	0.562879358496	0.999	0.70724093914	-4.64	0.478	0.725	0.01	None	None	4.02E-06	0	2.9E-05	0	0	None	0	None	4.02E-06	0	0	0	None	N	None
6626	53	G/R	rs770749098	0.5162	gnomAD-4.0.0	131	None	0.4217	0.4343	25.2	N	-0.671	0.76	0.033537	-0.35	0.3333	-0.4358	0.497842640141	None	0.996612	0.789	0.562879358496	0.999	0.70724093914	-4.64	0.478	0.725	0.01	None	None	1.59237E-06	0	2.28655E-05	0	0	None	0	0	1.59237E-06	0	0	0	None	N	None
6626	53	G/V	rs1362220931	0.5162	gnomAD-4.0.0	131	None	0.3192	0.2883	24.6	N	None	0.71	0.033076	-0.294	0.2452	-0.6418	0.333148620394	None	0.999993	0.755	0.531484362937	0.884	0.622422099113	-5.25	0.301	0.528	0.002	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6627	54	S/L	rs773143754	0.3352	gnomAD-2.1.1	134	None	0.1038	0.0967	None	N	-0.162	None	None	-0.121	None	None	None	None	None	None	None	0.037	None	None	0.259	0.307	None	None	None	1.43E-05	0	5.66E-05	0	1.02491E-04	None	0	None	1.43E-05	0	0	0	None	N	None
6627	54	S/L	rs773143754	0.3352	gnomAD-3.1.2	134	None	0.1038	0.0967	None	N	-0.162	None	None	-0.121	None	None	None	None	None	None	None	0.037	None	None	0.259	0.307	None	None	None	6.58E-06	0	0	0	1.93424E-04	None	0	0	6.58E-06	0	0	0	None	N	None
6627	54	S/L	rs773143754	0.3352	gnomAD-4.0.0	134	None	0.1038	0.0967	None	N	-0.162	None	None	-0.121	None	None	None	None	None	None	None	0.037	None	None	0.259	0.307	None	None	None	9.919E-06	0	1.66761E-05	0	2.22975E-05	None	0	0	9.919E-06	2.54363E-06	8.7885E-05	4.80507E-05	None	N	None
6628	55	T/P	None	0.1453	gnomAD-4.0.0	135	None	0.2892	0.2686	23.8	D	None	-0.33	0.025874	-0.547	0.3697	-0.2704	0.371760189014	None	0.504693	0.6	0.476754456241	0.937	0.481850862503	-3.41	0.507	0.607	0.246	None	None	6.00161E-06	0	0	0	0	None	0	0	6.00161E-06	6.56251E-06	0	0	None	N	None
6629	56	S/G	rs1484625101	0.1137	gnomAD-2.1.1	136	None	0.0848	0.0717	20.8	N	-1.507	0.92	0.010938	-1.095	0.0591	-1.0645	0.0768560786463	None	1.0	0.565	0.0666544352282	None	0.403234958649	-1.78	0.097	0.369	0.33	None	None	4.02E-06	0	2.9E-05	0	0	None	0	None	4.02E-06	0	0	0	None	N	None
6629	56	S/G	rs1484625101	0.1137	gnomAD-4.0.0	136	None	0.0848	0.0717	20.8	N	-1.507	0.92	0.010938	-1.095	0.0591	-1.0645	0.0768560786463	None	1.0	0.565	0.0666544352282	None	0.403234958649	-1.78	0.097	0.369	0.33	None	None	1.59241E-06	0	2.28655E-05	0	0	None	0	0	1.59241E-06	0	0	0	None	N	None
6629	56	S/I	rs2079601523	0.1137	gnomAD-3.1.2	136	None	0.195	0.1897	21.3	N	None	0.93	0.02097	0.459	0.1368	-0.8795	0.112047080189	None	1.0	0.511	0.259272394797	0.01	0.457602679729	-2.71	0.224	0.754	0.391	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
6629	56	S/I	rs2079601523	0.1137	gnomAD-4.0.0	136	None	0.195	0.1897	21.3	N	None	0.93	0.02097	0.459	0.1368	-0.8795	0.112047080189	None	1.0	0.511	0.259272394797	0.01	0.457602679729	-2.71	0.224	0.754	0.391	None	None	6.57748E-06	0	0	0	0	None	0	0	6.57748E-06	1.47072E-05	0	0	None	N	None
6630	57	F/L	rs1259557024	0.1963	gnomAD-2.1.1	137	None	0.8499	0.8531	23.6	N	-1.426	-0.21	0.045974	-1.565	0.3031	-0.5129	0.420742602379	None	1.0	0.432	0.483741690565	0.994	0.744158327579	-2.85	0.438	0.554	0.443	None	None	4.02E-06	0	2.9E-05	0	0	None	0	None	4.02E-06	0	0	0	None	N	None
6630	57	F/L	rs1259557024	0.1963	gnomAD-3.1.2	137	None	0.8499	0.8531	23.6	N	-1.426	-0.21	0.045974	-1.565	0.3031	-0.5129	0.420742602379	None	1.0	0.432	0.483741690565	0.994	0.744158327579	-2.85	0.438	0.554	0.443	None	None	1.31E-05	0	1.31044E-04	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
6630	57	F/L	rs1259557024	0.1963	gnomAD-4.0.0	137	None	0.8499	0.8531	23.6	N	-1.426	-0.21	0.045974	-1.565	0.3031	-0.5129	0.420742602379	None	1.0	0.432	0.483741690565	0.994	0.744158327579	-2.85	0.438	0.554	0.443	None	None	5.12771E-06	0	6.78012E-05	0	0	None	0	0	5.12771E-06	0	0	0	None	N	None
6630	57	F/V	rs1259557024	0.1963	gnomAD-3.1.2	137	None	0.2268	0.2234	27.2	N	None	-0.21	0.043217	-1.893	0.267	-0.3365	0.497562604243	None	0.812499	0.425	0.793855663125	0.994	0.707436323166	-3.13	0.546	0.573	0.273	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07383E-04	0	None	N	None
6630	57	F/V	rs1259557024	0.1963	gnomAD-4.0.0	137	None	0.2268	0.2234	27.2	N	None	-0.21	0.043217	-1.893	0.267	-0.3365	0.497562604243	None	0.812499	0.425	0.793855663125	0.994	0.707436323166	-3.13	0.546	0.573	0.273	None	None	2.56385E-06	0	0	0	0	None	0	0	2.56385E-06	0	2.68161E-05	0	None	N	None
6631	58	L/S	None	0.0760	gnomAD-4.0.0	138	None	0.9818	0.9783	26.5	D	None	-0.75	0.093466	-3.181	0.7198	0.7181	0.544358781492	None	0.672057	0.835	0.88376241617	1.0	0.714087665081	-3.93	0.806	0.888	0.001	None	None	1.36887E-06	0	0	0	0	None	0	0	1.36887E-06	1.79948E-06	0	0	None	N	None
6634	61	Y/C	rs2079599735	0.3920	gnomAD-3.1.2	141	None	0.2307	0.1965	28.3	N	None	-0.26	0.030831	-0.295	0.4129	-0.1607	0.465924040457	None	1.0	0.441	0.685574053984	0.997	0.669969081879	-4.83	0.442	0.47	0.059	None	None	6.58E-06	2.42E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
6634	61	Y/C	rs2079599735	0.3920	gnomAD-4.0.0	141	None	0.2307	0.1965	28.3	N	None	-0.26	0.030831	-0.295	0.4129	-0.1607	0.465924040457	None	1.0	0.441	0.685574053984	0.997	0.669969081879	-4.83	0.442	0.47	0.059	None	None	7.10648E-06	1.74966E-05	0	0	0	None	0	0	7.10648E-06	7.23027E-06	0	0	None	N	None
6634	61	Y/H	rs1211263186	0.3920	gnomAD-2.1.1	141	None	0.213	0.1708	22.8	N	-0.023	-0.23	0.019125	-0.538	0.2382	-0.7382	0.127094639181	None	1.0	0.486	0.310147130316	0.028	0.677264273167	-2.1	0.326	0.239	0.349	None	None	8.04E-06	0	0	0	0	None	6.54E-05	None	8.04E-06	0	0	0	None	N	None
6634	61	Y/H	rs1211263186	0.3920	gnomAD-4.0.0	141	None	0.213	0.1708	22.8	N	-0.023	-0.23	0.019125	-0.538	0.2382	-0.7382	0.127094639181	None	1.0	0.486	0.310147130316	0.028	0.677264273167	-2.1	0.326	0.239	0.349	None	None	4.77779E-06	0	0	0	0	None	0	0	4.77779E-06	0	4.30108E-05	0	None	N	None
6636	63	V/A	rs1258812731	0.1278	gnomAD-2.1.1	144	None	0.3178	0.3004	25.7	D	-2.191	-0.34	0.034981	-2.013	0.4417	-0.118	0.507641427205	None	0.972183	0.721	0.729420930906	1.0	0.69053542614	-2.07	0.499	0.531	0.223	None	None	1.61E-05	0	1.1605E-04	0	0	None	0	None	1.61E-05	0	0	0	None	N	None
6636	63	V/A	rs1258812731	0.1278	gnomAD-4.0.0	144	None	0.3178	0.3004	25.7	D	-2.191	-0.34	0.034981	-2.013	0.4417	-0.118	0.507641427205	None	0.972183	0.721	0.729420930906	1.0	0.69053542614	-2.07	0.499	0.531	0.223	None	None	4.77824E-06	0	6.86091E-05	0	0	None	0	0	4.77824E-06	0	0	0	None	N	None
6637	64	D/G	rs1240731918	0.3595	gnomAD-2.1.1	145	None	0.2446	0.2411	23.8	N	-0.302	-0.27	0.03469	-0.63	0.2118	-0.8089	0.112508237102	None	1.0	0.529	0.187945064343	0.015	0.577844500542	-3.9	0.324	0.136	0.382	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
6637	64	D/G	rs1240731918	0.3595	gnomAD-3.1.2	145	None	0.2446	0.2411	23.8	N	-0.302	-0.27	0.03469	-0.63	0.2118	-0.8089	0.112508237102	None	1.0	0.529	0.187945064343	0.015	0.577844500542	-3.9	0.324	0.136	0.382	None	None	1.32E-05	4.83E-05	0	0	0	None	0	0	1.32E-05	0	0	0	None	N	None
6637	64	D/G	rs1240731918	0.3595	gnomAD-4.0.0	145	None	0.2446	0.2411	23.8	N	-0.302	-0.27	0.03469	-0.63	0.2118	-0.8089	0.112508237102	None	1.0	0.529	0.187945064343	0.015	0.577844500542	-3.9	0.324	0.136	0.382	None	None	1.31546E-05	4.83022E-05	0	0	0	None	0	0	1.31546E-05	0	0	0	None	N	None
6637	64	D/V	None	0.3595	gnomAD-4.0.0	145	None	0.3872	0.4019	24.0	N	None	-0.29	0.050263	-0.009	0.2372	-0.5742	0.285193088434	None	0.994774	0.533	0.57026793815	0.92	0.561808943748	-4.53	0.421	0.399	0.315	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6637	64	D/Y	None	0.3595	gnomAD-4.0.0	145	None	0.4255	0.4327	23.8	D	None	-0.3	0.025629	-0.076	0.4338	-0.2018	0.454799302638	None	1.0	0.527	0.684780014046	0.996	0.633220791817	-4.74	0.421	0.39	0.03	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
6638	65	A/T	rs878890344	0.5274	gnomAD-3.1.2	146	None	0.0762	0.0763	20.2	N	None	0.99	0.008144	-0.589	0.0455	-1.0915	0.0817464375466	None	1.0	0.408	0.0482279557977	None	0.428776621819	-1.47	0.095	0.221	0.463	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
6638	65	A/T	rs878890344	0.5274	gnomAD-4.0.0	146	None	0.0762	0.0763	20.2	N	None	0.99	0.008144	-0.589	0.0455	-1.0915	0.0817464375466	None	1.0	0.408	0.0482279557977	None	0.428776621819	-1.47	0.095	0.221	0.463	None	None	3.72E-06	0	0	0	0	None	0	0	3.72E-06	5.08783E-06	0	0	None	N	None
6640	67	K/E	None	0.2408	gnomAD-4.0.0	149	None	0.1375	0.1546	22.5	N	None	-0.16	0.021735	-0.127	0.1296	-0.8346	0.176437022422	None	1.0	0.496	0.303123707472	0.27	0.544443249702	-1.26	0.192	0.545	0.41	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6641	68	T/A	None	0.3214	gnomAD-4.0.0	151	None	0.0889	0.077	22.0	N	None	-0.14	0.014733	-0.915	0.0774	-1.0643	0.0823094008257	None	1.0	0.402	0.0884992946249	0.001	0.576631188393	-2.06	0.096	0.141	0.716	None	None	1.5932E-06	0	0	0	0	None	0	0	1.5932E-06	2.86202E-06	0	0	None	N	None
6641	68	T/I	rs747240394	0.3214	gnomAD-3.1.2	151	None	0.3739	0.2954	23.0	N	None	-0.29	0.030154	-0.331	0.2626	-0.5971	0.171473513557	None	1.0	0.481	0.332133492242	0.175	0.676143586636	-3.15	0.135	0.539	0.159	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
6641	68	T/I	rs747240394	0.3214	gnomAD-4.0.0	151	None	0.3739	0.2954	23.0	N	None	-0.29	0.030154	-0.331	0.2626	-0.5971	0.171473513557	None	1.0	0.481	0.332133492242	0.175	0.676143586636	-3.15	0.135	0.539	0.159	None	None	6.57601E-06	0	6.55652E-05	0	0	None	0	0	6.57601E-06	0	0	0	None	N	None
6641	68	T/N	rs747240394	0.3214	gnomAD-2.1.1	151	None	0.1523	0.1389	22.7	N	-0.292	-0.25	0.021501	-0.468	0.222	-0.7369	0.118878650778	None	1.0	0.39	0.262662153117	0.096	0.636036455631	-2.51	0.089	0.467	0.299	None	None	2.93278E-04	0	2.26667E-03	0	0	None	0	None	2.93278E-04	0	0	2.81849E-04	None	N	None
6641	68	T/N	rs747240394	0.3214	gnomAD-3.1.2	151	None	0.1523	0.1389	22.7	N	-0.292	-0.25	0.021501	-0.468	0.222	-0.7369	0.118878650778	None	1.0	0.39	0.262662153117	0.096	0.636036455631	-2.51	0.089	0.467	0.299	None	None	7.23E-05	0	7.21217E-04	0	0	None	0	0	7.23E-05	0	0	0	None	N	None
6641	68	T/N	rs747240394	0.3214	gnomAD-4.0.0	151	None	0.1523	0.1389	22.7	N	-0.292	-0.25	0.021501	-0.468	0.222	-0.7369	0.118878650778	None	1.0	0.39	0.262662153117	0.096	0.636036455631	-2.51	0.089	0.467	0.299	None	None	1.23129E-04	0	1.61148E-03	0	0	None	0	0	1.23129E-04	0	0	2.84689E-05	None	N	None
6641	68	T/P	rs768808788	0.3214	gnomAD-2.1.1	151	None	0.2515	0.2282	22.3	D	-0.597	-0.29	0.033234	-0.494	0.2644	-0.6747	0.198521476201	None	1.0	0.494	0.321108458156	0.301	0.581386864185	-3.08	0.259	0.544	0.168	None	None	4.03E-06	0	0	0	0	None	3.28E-05	None	4.03E-06	0	0	0	None	N	None
6641	68	T/P	rs768808788	0.3214	gnomAD-4.0.0	151	None	0.2515	0.2282	22.3	D	-0.597	-0.29	0.033234	-0.494	0.2644	-0.6747	0.198521476201	None	1.0	0.494	0.321108458156	0.301	0.581386864185	-3.08	0.259	0.544	0.168	None	None	1.5932E-06	0	0	0	0	None	0	0	1.5932E-06	0	1.43497E-05	0	None	N	None
6643	70	Q/E	None	0.6189	gnomAD-4.0.0	153	None	0.0728	0.0759	21.1	N	None	-0.18	0.019783	-0.678	0.1282	-0.9496	0.0904167817641	None	1.0	0.493	0.165133752707	None	0.441272497177	-0.94	0.184	0.113	0.645	None	None	1.59555E-06	0	2.29589E-05	0	0	None	0	0	1.59555E-06	0	0	0	None	N	None
6643	70	Q/H	None	0.6189	gnomAD-4.0.0	153	None	0.1117	0.115	18.72	N	None	-0.3	0.017038	-0.919	0.1585	-1.034	0.078622320537	None	1.0	0.503	0.0401082797425	None	0.459062308073	-1.92	0.191	0.117	0.58	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6643	70	Q/R	rs1399714010	0.6189	gnomAD-2.1.1	153	None	0.079	0.0893	23.0	N	0.203	-0.24	0.009513	-0.043	0.1316	-0.9322	0.0898045773999	None	1.0	0.446	0.137902524267	None	0.454748570919	-1.97	0.134	0.122	0.534	None	None	4.06E-06	0	0	0	0	None	0	None	4.06E-06	0	8.96E-06	0	None	N	None
6643	70	Q/R	rs1399714010	0.6189	gnomAD-4.0.0	153	None	0.079	0.0893	23.0	N	0.203	-0.24	0.009513	-0.043	0.1316	-0.9322	0.0898045773999	None	1.0	0.446	0.137902524267	None	0.454748570919	-1.97	0.134	0.122	0.534	None	None	4.1136E-06	0	0	0	0	None	0	0	4.1136E-06	5.40256E-06	0	0	None	N	None
6644	71	Y/C	rs375417679	0.1064	gnomAD-2.1.1	154	None	0.8905	0.8894	None	D	None	None	None	-1.116	None	None	None	None	None	None	None	1.0	None	None	0.875	0.877	None	None	None	4.06E-06	0	2.94E-05	0	0	None	0	None	4.06E-06	0	0	0	None	N	None
6644	71	Y/C	rs375417679	0.1064	gnomAD-3.1.2	154	None	0.8905	0.8894	None	D	None	None	None	-1.116	None	None	None	None	None	None	None	1.0	None	None	0.875	0.877	None	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
6644	71	Y/C	rs375417679	0.1064	gnomAD-4.0.0	154	None	0.8905	0.8894	None	D	None	None	None	-1.116	None	None	None	None	None	None	None	1.0	None	None	0.875	0.877	None	None	None	1.86266E-06	0	5.04117E-05	0	0	None	0	0	1.86266E-06	0	0	0	None	N	None
6645	72	T/A	rs370671112	0.1763	gnomAD-2.1.1	155	None	0.0993	0.106	None	N	-1.186	None	None	-1.02	None	None	None	None	None	None	None	0.925	None	None	0.258	0.615	None	None	None	2.54E-05	0	0	0	0	None	3.4E-05	None	2.54E-05	0	4.74E-05	0	None	N	None
6645	72	T/A	rs370671112	0.1763	gnomAD-3.1.2	155	None	0.0993	0.106	None	N	-1.186	None	None	-1.02	None	None	None	None	None	None	None	0.925	None	None	0.258	0.615	None	None	None	2.63E-05	0	0	0	0	None	0	0	2.63E-05	5.88E-05	0	0	None	N	None
6645	72	T/A	rs370671112	0.1763	gnomAD-4.0.0	155	None	0.0993	0.106	None	N	-1.186	None	None	-1.02	None	None	None	None	None	None	None	0.925	None	None	0.258	0.615	None	None	None	2.36301E-05	0	0	0	0	None	0	0	2.36301E-05	3.05744E-05	1.11349E-05	1.60658E-05	None	N	None
6646	73	C/Y	rs575692993	0.0744	gnomAD-2.1.1	156	None	0.9236	0.9236	24.8	D	-1.63	-0.12	0.120591	-1.276	0.6554	0.6024	0.601348376114	None	0.999645	0.791	0.810174296794	1.0	0.847177326679	-7.51	0.579	0.914	0.16	None	None	1.23E-05	0	0	0	0	None	1.03079E-04	None	1.23E-05	0	0	0	None	N	None
6646	73	C/Y	rs575692993	0.0744	gnomAD-3.1.2	156	None	0.9236	0.9236	24.8	D	-1.63	-0.12	0.120591	-1.276	0.6554	0.6024	0.601348376114	None	0.999645	0.791	0.810174296794	1.0	0.847177326679	-7.51	0.579	0.914	0.16	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	0	2.06954E-04	0	None	N	None
6646	73	C/Y	rs575692993	0.0744	1000 genomes	156	None	0.9236	0.9236	24.8	D	-1.63	-0.12	0.120591	-1.276	0.6554	0.6024	0.601348376114	None	0.999645	0.791	0.810174296794	1.0	0.847177326679	-7.51	0.579	0.914	0.16	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	N	None
6646	73	C/Y	rs575692993	0.0744	gnomAD-4.0.0	156	None	0.9236	0.9236	24.8	D	-1.63	-0.12	0.120591	-1.276	0.6554	0.6024	0.601348376114	None	0.999645	0.791	0.810174296794	1.0	0.847177326679	-7.51	0.579	0.914	0.16	None	None	3.7348E-06	0	0	0	0	None	0	0	3.7348E-06	0	4.47417E-05	3.21657E-05	None	N	None
6647	74	H/Q	rs565190478	0.3586	gnomAD-3.1.2	157	None	0.0669	0.0715	21.0	N	-0.723	-0.08	0.029561	-0.828	0.0725	-1.093	0.0837231850671	None	1.0	0.373	0.0401082797425	None	0.456501185894	0.09	0.097	0.174	0.756	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
6647	74	H/Q	rs565190478	0.3586	1000 genomes	157	None	0.0669	0.0715	21.0	N	-0.723	-0.08	0.029561	-0.828	0.0725	-1.093	0.0837231850671	None	1.0	0.373	0.0401082797425	None	0.456501185894	0.09	0.097	0.174	0.756	None	None	1.99681E-04	0	0	None	0	1E-03	None	None	1.99681E-04	None	0	None	None	N	None
6647	74	H/Q	rs565190478	0.3586	gnomAD-4.0.0	157	None	0.0669	0.0715	21.0	N	-0.723	-0.08	0.029561	-0.828	0.0725	-1.093	0.0837231850671	None	1.0	0.373	0.0401082797425	None	0.456501185894	0.09	0.097	0.174	0.756	None	None	6.00161E-06	0	0	0	0	None	0	0	6.00161E-06	6.56251E-06	0	0	None	N	None
6647	74	H/R	rs757799209	0.3586	gnomAD-2.1.1	157	None	0.0664	0.0815	23.4	N	-1.138	-0.13	0.048714	-1.087	0.1317	-0.9528	0.102109692454	None	1.0	0.46	0.197625483188	None	0.478401005268	-1.34	0.154	0.194	0.39	None	None	4.19E-06	0	0	0	5.66E-05	None	0	None	4.19E-06	0	0	0	None	N	None
6647	74	H/R	rs757799209	0.3586	gnomAD-4.0.0	157	None	0.0664	0.0815	23.4	N	-1.138	-0.13	0.048714	-1.087	0.1317	-0.9528	0.102109692454	None	1.0	0.46	0.197625483188	None	0.478401005268	-1.34	0.154	0.194	0.39	None	None	2.75954E-06	0	0	0	2.52755E-05	None	0	0	2.75954E-06	2.71139E-06	0	0	None	N	None
6648	75	V/A	None	0.1012	gnomAD-4.0.0	158	None	0.3711	0.3863	24.9	N	None	0.21	0.021693	-2.241	0.1939	-0.6991	0.338082227009	None	0.748025	0.576	0.53974568202	0.939	0.758015275002	-2.33	0.309	0.612	0.356	None	None	6.90254E-07	0	0	0	0	None	0	0	6.90254E-07	0	0	1.67051E-05	None	N	None
6648	75	V/G	rs752299031	0.1012	gnomAD-2.1.1	158	None	0.6976	0.7118	25.9	N	-3.252	-0.61	0.079604	-2.771	0.567	0.2521	0.499973522767	None	0.999981	0.659	0.928001726772	0.997	0.663256883621	-4.23	0.723	0.843	0.001	None	None	8.41E-06	0	0	0	0	None	0	None	8.41E-06	0	1.83E-05	0	None	N	None
6648	75	V/G	rs752299031	0.1012	gnomAD-4.0.0	158	None	0.6976	0.7118	25.9	N	-3.252	-0.61	0.079604	-2.771	0.567	0.2521	0.499973522767	None	0.999981	0.659	0.928001726772	0.997	0.663256883621	-4.23	0.723	0.843	0.001	None	None	1.38051E-06	0	0	0	0	None	0	0	1.38051E-06	1.80831E-06	0	0	None	N	None
6649	76	T/I	rs767035458	0.3367	gnomAD-2.1.1	159	None	0.1937	0.1962	21.8	D	-0.013	-0.44	0.034724	-0.396	0.2924	-0.5609	0.136034570782	None	1.0	0.503	0.537402380065	0.351	0.715067386627	-3.09	0.261	0.46	0.148	None	None	4.2E-06	0	0	0	0	None	0	None	4.2E-06	0	9.17E-06	0	None	N	None
6649	76	T/I	rs767035458	0.3367	gnomAD-4.0.0	159	None	0.1937	0.1962	21.8	D	-0.013	-0.44	0.034724	-0.396	0.2924	-0.5609	0.136034570782	None	1.0	0.503	0.537402380065	0.351	0.715067386627	-3.09	0.261	0.46	0.148	None	None	1.62667E-06	0	0	0	0	None	0	0	1.62667E-06	2.9108E-06	0	0	None	N	None
6650	77	N/S	rs751222632	0.1424	gnomAD-2.1.1	161	None	0.4457	0.3325	26.3	N	-1.14	0.32	0.017574	-1.09	0.4917	0.1709	0.415421845615	None	0.881936	0.832	0.294206760003	0.999	0.577398836613	-2.94	0.593	0.562	0.031	None	None	1.11E-05	0	0	0	0	None	0	None	1.11E-05	0	1.61E-05	1.468E-04	None	N	None
6650	77	N/S	rs751222632	0.1424	gnomAD-3.1.2	161	None	0.4457	0.3325	26.3	N	-1.14	0.32	0.017574	-1.09	0.4917	0.1709	0.415421845615	None	0.881936	0.832	0.294206760003	0.999	0.577398836613	-2.94	0.593	0.562	0.031	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	1.47E-05	0	4.78011E-04	None	N	None
6650	77	N/S	rs751222632	0.1424	gnomAD-4.0.0	161	None	0.4457	0.3325	26.3	N	-1.14	0.32	0.017574	-1.09	0.4917	0.1709	0.415421845615	None	0.881936	0.832	0.294206760003	0.999	0.577398836613	-2.94	0.593	0.562	0.031	None	None	6.52387E-06	1.7118E-05	0	0	0	None	0	0	6.52387E-06	7.2926E-06	0	2.89184E-05	None	N	None
6650	77	N/T	rs751222632	0.1424	gnomAD-2.1.1	161	None	0.8778	0.8066	27.3	D	-0.778	0.27	0.112551	-0.765	0.5888	0.5473	0.467888205126	None	0.960702	0.839	0.558889990735	1.0	0.620094716549	-3.59	0.7	0.708	0.012	None	None	4.21E-06	0	3.13E-05	0	0	None	0	None	4.21E-06	0	0	0	None	N	None
6650	77	N/T	rs751222632	0.1424	gnomAD-4.0.0	161	None	0.8778	0.8066	27.3	D	-0.778	0.27	0.112551	-0.765	0.5888	0.5473	0.467888205126	None	0.960702	0.839	0.558889990735	1.0	0.620094716549	-3.59	0.7	0.708	0.012	None	None	1.62767E-06	0	2.41709E-05	0	0	None	0	0	1.62767E-06	0	0	0	None	N	None
6653	80	G/A	rs1446415238	0.2202	gnomAD-2.1.1	164	None	0.672	0.6632	23.9	D	-0.291	-0.86	0.043843	-0.404	0.6815	0.4749	0.47212284556	None	0.964455	0.92	0.516326692288	1.0	0.691712200642	-3.24	0.65	0.616	0.031	None	None	8.44E-06	0	0	0	0	None	7.24E-05	None	8.44E-06	0	0	0	None	I	None
6653	80	G/A	rs1446415238	0.2202	gnomAD-3.1.2	164	None	0.672	0.6632	23.9	D	-0.291	-0.86	0.043843	-0.404	0.6815	0.4749	0.47212284556	None	0.964455	0.92	0.516326692288	1.0	0.691712200642	-3.24	0.65	0.616	0.031	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	0	2.07039E-04	0	None	I	None
6653	80	G/A	rs1446415238	0.2202	gnomAD-4.0.0	164	None	0.672	0.6632	23.9	D	-0.291	-0.86	0.043843	-0.404	0.6815	0.4749	0.47212284556	None	0.964455	0.92	0.516326692288	1.0	0.691712200642	-3.24	0.65	0.616	0.031	None	None	6.26272E-06	0	0	0	0	None	0	0	6.26272E-06	0	1.13729E-04	0	None	I	None
6653	80	G/D	rs1446415238	0.2202	gnomAD-4.0.0	164	None	0.8668	0.8926	23.7	D	None	-0.84	0.060453	-0.842	0.6326	0.4526	0.366674787173	None	0.990048	0.901	0.55025283692	0.975	0.77103638649	-3.92	0.621	0.547	0.009	None	None	1.38437E-06	0	0	0	5.0615E-05	None	0	0	1.38437E-06	0	0	0	None	I	None
6653	80	G/R	None	0.2202	gnomAD-4.0.0	164	None	0.9246	0.9416	26.7	D	None	-0.87	0.048129	-0.373	0.7221	0.6204	0.505070386953	None	0.999032	0.912	0.850381006097	1.0	0.76802021265	-4.37	0.705	0.803	0.004	None	None	1.63463E-06	0	0	0	0	None	0	0	1.63463E-06	2.92535E-06	0	0	None	I	None
6655	82	D/G	rs772947420	0.2856	gnomAD-2.1.1	166	None	0.2094	0.2132	None	D	-0.943	None	None	-0.987	None	None	None	None	None	None	None	0.933	None	None	0.322	0.507	None	None	None	2.27E-05	2.09153E-04	3.11E-05	0	0	None	0	None	2.27E-05	0	0	0	None	I	None
6655	82	D/G	rs772947420	0.2856	gnomAD-3.1.2	166	None	0.2094	0.2132	None	D	-0.943	None	None	-0.987	None	None	None	None	None	None	None	0.933	None	None	0.322	0.507	None	None	None	3.3E-05	1.21236E-04	0	0	0	None	0	0	3.3E-05	0	0	0	None	I	None
6655	82	D/G	rs772947420	0.2856	gnomAD-4.0.0	166	None	0.2094	0.2132	None	D	-0.943	None	None	-0.987	None	None	None	None	None	None	None	0.933	None	None	0.322	0.507	None	None	None	1.32081E-05	1.55333E-04	1.80187E-05	0	0	None	0	0	1.32081E-05	0	0	0	None	I	None
6655	82	D/N	rs397517493	0.2856	gnomAD-2.1.1	166	None	0.1136	0.1174	23.8	N	-0.636	-0.28	0.0316	-0.536	0.4925	-0.0409	0.414400824624	None	0.942969	0.455	0.378847511475	1.0	0.609625041485	-2.58	0.376	0.565	0.172	None	None	3.77E-05	0	3.1E-05	0	3.13414E-04	None	3.73E-05	None	3.77E-05	0	1.63E-05	0	None	I	None
6655	82	D/N	rs397517493	0.2856	gnomAD-3.1.2	166	None	0.1136	0.1174	23.8	N	-0.636	-0.28	0.0316	-0.536	0.4925	-0.0409	0.414400824624	None	0.942969	0.455	0.378847511475	1.0	0.609625041485	-2.58	0.376	0.565	0.172	None	None	2.63E-05	0	0	0	1.93424E-04	None	0	0	2.63E-05	4.41E-05	0	0	None	I	None
6655	82	D/N	rs397517493	0.2856	gnomAD-4.0.0	166	None	0.1136	0.1174	23.8	N	-0.636	-0.28	0.0316	-0.536	0.4925	-0.0409	0.414400824624	None	0.942969	0.455	0.378847511475	1.0	0.609625041485	-2.58	0.376	0.565	0.172	None	None	6.03057E-05	0	1.76579E-05	0	1.34342E-04	None	0	0	6.03057E-05	7.35503E-05	1.14924E-05	3.24897E-05	None	I	None
6656	83	S/C	rs761716450	0.3151	gnomAD-2.1.1	168	None	0.1521	0.1285	23.0	D	-0.216	-0.38	0.034743	-0.311	0.459	0.1936	0.239176144901	None	1.0	0.476	0.603223074362	0.962	0.500228881836	-3.02	0.464	0.504	0.005	None	None	8.59E-06	0	0	0	0	None	0	None	8.59E-06	0	1.87E-05	0	None	I	None
6656	83	S/C	rs761716450	0.3151	gnomAD-4.0.0	168	None	0.1521	0.1285	23.0	D	-0.216	-0.38	0.034743	-0.311	0.459	0.1936	0.239176144901	None	1.0	0.476	0.603223074362	0.962	0.500228881836	-3.02	0.464	0.504	0.005	None	None	1.38996E-06	0	0	0	0	None	0	0	1.38996E-06	1.81675E-06	0	0	None	I	None
6656	83	S/F	rs761716450	0.3151	gnomAD-2.1.1	168	None	0.1445	0.1382	22.9	N	-0.953	-0.36	0.055493	-0.987	0.3525	-0.3967	0.0940302031534	None	1.0	0.476	0.614227455099	0.011	0.530482411385	-3.67	0.292	0.493	0.046	None	None	8.59E-06	0	0	0	0	None	0	None	8.59E-06	0	1.87E-05	0	None	I	None
6656	83	S/F	rs761716450	0.3151	gnomAD-4.0.0	168	None	0.1445	0.1382	22.9	N	-0.953	-0.36	0.055493	-0.987	0.3525	-0.3967	0.0940302031534	None	1.0	0.476	0.614227455099	0.011	0.530482411385	-3.67	0.292	0.493	0.046	None	None	3.47491E-06	0	0	0	0	None	0	0	3.47491E-06	4.54188E-06	0	0	None	I	None
6657	84	C/F	rs776748717	0.1604	gnomAD-2.1.1	169	None	0.3659	0.3456	26.8	N	-1.532	-0.26	0.047219	-1.503	0.5286	0.0399	0.571919452751	None	0.999899	0.513	0.843383936846	1.0	0.738334715366	-5.63	0.461	0.874	0.021	None	None	7.6E-06	0	0	0	1.04471E-04	None	0	None	7.6E-06	0	0	0	None	N	None
6657	84	C/F	rs776748717	0.1604	gnomAD-3.1.2	169	None	0.3659	0.3456	26.8	N	-1.532	-0.26	0.047219	-1.503	0.5286	0.0399	0.571919452751	None	0.999899	0.513	0.843383936846	1.0	0.738334715366	-5.63	0.461	0.874	0.021	None	None	6.58E-06	0	0	0	1.93199E-04	None	0	0	6.58E-06	0	0	0	None	N	None
6657	84	C/F	rs776748717	0.1604	gnomAD-4.0.0	169	None	0.3659	0.3456	26.8	N	-1.532	-0.26	0.047219	-1.503	0.5286	0.0399	0.571919452751	None	0.999899	0.513	0.843383936846	1.0	0.738334715366	-5.63	0.461	0.874	0.021	None	None	2.51707E-06	0	0	0	4.48189E-05	None	0	0	2.51707E-06	0	0	3.25489E-05	None	N	None
6657	84	C/Y	None	0.1604	gnomAD-4.0.0	169	None	0.6197	0.5787	26.5	D	None	-0.27	0.037092	-1.578	0.4654	-0.1386	0.601348376114	None	0.999707	0.521	0.807364678773	1.0	0.804408013821	-5.6	0.47	0.874	0.027	None	None	1.3917E-06	0	0	0	0	None	0	0	1.3917E-06	1.81817E-06	0	0	None	N	None
6659	86	T/A	rs768775530	0.1248	gnomAD-2.1.1	172	None	0.0604	0.0584	21.8	N	-1.482	0.03	0.013097	-1.063	0.1118	-0.9017	0.0970645247333	None	1.0	0.416	0.178374595973	0.219	0.484957933426	-2.26	0.209	0.279	0.792	None	None	4.41E-06	0	3.34E-05	0	0	None	0	None	4.41E-06	0	0	0	None	I	None
6659	86	T/A	rs768775530	0.1248	gnomAD-4.0.0	172	None	0.0604	0.0584	21.8	N	-1.482	0.03	0.013097	-1.063	0.1118	-0.9017	0.0970645247333	None	1.0	0.416	0.178374595973	0.219	0.484957933426	-2.26	0.209	0.279	0.792	None	None	3.35386E-06	0	5.17357E-05	0	0	None	0	0	3.35386E-06	0	0	0	None	I	None
6659	86	T/M	rs16866475	0.1248	gnomAD-2.1.1	172	None	0.1673	0.2062	None	N	-0.61	None	None	0.162	None	None	None	None	None	None	None	1.0	None	None	0.454	0.753	None	None	None	4.17069E-03	4.21008E-02	1.6429E-03	0	0	None	8.01E-05	None	4.17069E-03	0	8.35E-05	9.22793E-04	None	I	None
6659	86	T/M	rs16866475	0.1248	gnomAD-3.1.2	172	None	0.1673	0.2062	None	N	-0.61	None	None	0.162	None	None	None	None	None	None	None	1.0	None	None	0.454	0.753	None	None	None	1.19008E-02	4.18156E-02	3.54052E-03	0	0	None	0	0	1.19008E-02	1.1772E-04	0	7.6555E-03	None	I	None
6659	86	T/M	rs16866475	0.1248	1000 genomes	172	None	0.1673	0.2062	None	N	-0.61	None	None	0.162	None	None	None	None	None	None	None	1.0	None	None	0.454	0.753	None	None	None	1.65735E-02	5.98E-02	5.8E-03	None	0	0	None	None	1.65735E-02	None	0	None	None	I	None
6659	86	T/M	rs16866475	0.1248	gnomAD-4.0.0	172	None	0.1673	0.2062	None	N	-0.61	None	None	0.162	None	None	None	None	None	None	None	1.0	None	None	0.454	0.753	None	None	None	2.25599E-03	4.29566E-02	2.61914E-03	0	0	None	0	1.1925E-03	2.25599E-03	6.70306E-05	7.09471E-05	2.80632E-03	None	I	None
6660	87	M/I	None	0.5171	gnomAD-4.0.0	173	None	0.2147	0.1728	14.4	N	None	-0.2	0.027693	-0.695	0.1321	-0.9011	0.0942643627443	None	0.657628	0.441	0.270889551736	0.002	0.314466625452	-1.63	0.038	0.321	0.407	None	None	1.40711E-06	0	2.60078E-05	0	0	None	0	0	1.40711E-06	9.14875E-07	0	0	None	N	None
6660	87	M/L	rs780339252	0.5171	gnomAD-2.1.1	173	None	0.1113	0.1014	13.5	N	-0.123	-0.18	0.013777	-0.695	0.0956	-1.0143	0.0791812460476	None	1.0	0.427	0.371157983038	0.001	0.318313241005	-1.31	0.076	0.227	0.753	None	None	4.46E-06	0	0	0	0	None	0	None	4.46E-06	4.94E-05	0	0	None	N	None
6660	87	M/L	rs780339252	0.5171	gnomAD-4.0.0	173	None	0.1113	0.1014	13.5	N	-0.123	-0.18	0.013777	-0.695	0.0956	-1.0143	0.0791812460476	None	1.0	0.427	0.371157983038	0.001	0.318313241005	-1.31	0.076	0.227	0.753	None	None	5.06049E-06	0	0	0	0	None	1.91747E-05	0	5.06049E-06	6.00348E-06	0	0	None	N	None
6660	87	M/V	rs780339252	0.5171	gnomAD-2.1.1	173	None	0.0654	0.0593	12.63	N	-0.502	-0.19	0.022424	-1.001	0.0909	-1.0213	0.0845940308932	None	1.0	0.404	0.202086224978	None	0.294852435589	-1.37	0.138	0.088	0.542	None	None	4.46E-06	0	0	0	0	None	4.06E-05	None	4.46E-06	0	0	0	None	N	None
6660	87	M/V	rs780339252	0.5171	gnomAD-4.0.0	173	None	0.0654	0.0593	12.63	N	-0.502	-0.19	0.022424	-1.001	0.0909	-1.0213	0.0845940308932	None	1.0	0.404	0.202086224978	None	0.294852435589	-1.37	0.138	0.088	0.542	None	None	1.68683E-06	0	0	0	0	None	0	0	1.68683E-06	0	1.58856E-05	0	None	N	None
6661	88	L/S	rs772138264	0.1176	gnomAD-2.1.1	174	None	0.984	0.9816	26.8	D	-3.619	-0.1	0.048823	-3.757	0.6137	0.555	0.544358781492	None	0.620777	0.7	0.858812690212	1.0	0.669779777527	-3.4	0.705	0.889	0.032	None	None	9.12E-06	0	0	0	0	None	8.51E-05	None	9.12E-06	0	0	0	None	N	None
6661	88	L/S	rs772138264	0.1176	gnomAD-4.0.0	174	None	0.984	0.9816	26.8	D	-3.619	-0.1	0.048823	-3.757	0.6137	0.555	0.544358781492	None	0.620777	0.7	0.858812690212	1.0	0.669779777527	-3.4	0.705	0.889	0.032	None	None	8.51844E-06	0	0	0	0	None	0	0	8.51844E-06	0	6.46726E-05	3.19857E-05	None	N	None
6662	89	L/F	rs2079581150	0.5514	gnomAD-4.0.0	175	None	0.0957	0.089	22.0	N	None	-0.25	0.017813	-0.985	0.0944	-1.0035	0.0930364309948	None	1.0	0.436	0.38342384377	0.006	0.455529212952	-1.8	0.13	0.14	0.728	None	None	1.72006E-06	0	0	0	0	None	0	0	1.72006E-06	0	1.64447E-05	0	None	N	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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