TITINdb

Map SAVs to Structure

The data displayed in the table aims to be as complete as possible and contains information for all available sources including different versions of the same source, for example, different sources of gnomAD. To avoid seeing multiple entries for the same variant, we recommend to sort by Source first.

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
6199	1	P/A	1	None	0.1424	None	gnomAD-4.0.0	1.59492E-06
6199	1	P/L	1	rs758776829	0.1424	None	gnomAD-4.0.0	1.20032E-06
6200	2	T/I	2	rs1046417798	0.5409	None	gnomAD-4.0.0	1.20032E-06
6202	4	I/M	4	rs1041345186	0.4570	None	gnomAD-3.1.2	6.57E-06
6202	4	I/M	4	rs1041345186	0.4570	None	gnomAD-4.0.0	6.57324E-06
6202	4	I/N	4	None	0.4570	None	gnomAD-4.0.0	6.84698E-07
6202	4	I/T	4	rs1298665270	0.4570	None	gnomAD-2.1.1	8.07E-06
6202	4	I/T	4	rs1298665270	0.4570	None	gnomAD-3.1.2	6.57E-06
6202	4	I/T	4	rs1298665270	0.4570	None	gnomAD-4.0.0	6.20091E-06
6202	4	I/V	4	None	0.4570	None	gnomAD-4.0.0	1.20032E-06
6203	5	R/G	5	None	0.3274	None	gnomAD-4.0.0	1.59392E-06
6204	6	E/D	7	None	0.5262	None	gnomAD-4.0.0	6.8457E-07
6204	6	E/G	7	None	0.5262	None	gnomAD-4.0.0	1.20032E-06
6204	6	E/K	7	rs949942051	0.5262	None	gnomAD-4.0.0	1.36917E-06
6206	8	K/N	9	None	0.7794	None	gnomAD-4.0.0	6.8456E-07
6207	9	P/A	11	rs755803926	0.5990	None	gnomAD-2.1.1	4.03E-06
6207	9	P/A	11	rs755803926	0.5990	None	gnomAD-4.0.0	1.5931E-06
6207	9	P/S	11	None	0.5990	None	gnomAD-4.0.0	3.18619E-06
6208	10	V/L	13	rs759379332	0.2502	None	gnomAD-2.1.1	4.03E-06
6208	10	V/L	13	rs759379332	0.2502	None	gnomAD-4.0.0	1.59263E-06
6208	10	V/M	13	rs759379332	0.2502	None	gnomAD-2.1.1	1.21E-05
6208	10	V/M	13	rs759379332	0.2502	None	gnomAD-4.0.0	1.2741E-05
6209	11	E/K	14	rs751253663	0.3590	None	gnomAD-2.1.1	4.03E-06
6209	11	E/K	14	rs751253663	0.3590	None	gnomAD-4.0.0	1.59212E-06
6209	11	E/Q	14	rs751253663	0.3590	None	gnomAD-2.1.1	4.03E-06
6209	11	E/Q	14	rs751253663	0.3590	None	gnomAD-4.0.0	1.59212E-06
6210	12	V/I	16	rs766360972	0.2007	None	gnomAD-2.1.1	1.07E-05
6210	12	V/I	16	rs766360972	0.2007	None	gnomAD-3.1.2	3.29E-05
6210	12	V/I	16	rs766360972	0.2007	None	gnomAD-4.0.0	6.08971E-06
6211	13	V/A	18	rs773463426	0.3832	None	gnomAD-2.1.1	4.03E-06
6211	13	V/A	18	rs773463426	0.3832	None	gnomAD-4.0.0	1.59202E-06
6211	13	V/I	18	rs1236160546	0.3832	None	gnomAD-2.1.1	3.18E-05
6211	13	V/I	18	rs1236160546	0.3832	None	gnomAD-3.1.2	1.31E-05
6211	13	V/I	18	rs1236160546	0.3832	None	gnomAD-4.0.0	1.31447E-05
6213	15	Y/C	24	rs1489995255	0.5582	None	gnomAD-4.0.0	1.59189E-06
6213	15	Y/F	24	rs1489995255	0.5582	None	gnomAD-2.1.1	4.03E-06
6213	15	Y/F	24	rs1489995255	0.5582	None	gnomAD-4.0.0	1.59189E-06
6215	17	D/A	26	rs1267800654	0.4455	None	gnomAD-2.1.1	8.05E-06
6215	17	D/A	26	rs1267800654	0.4455	None	gnomAD-4.0.0	3.18369E-06
6216	18	V/M	28	rs369242073	0.1540	None	gnomAD-2.1.1	8.05E-06
6216	18	V/M	28	rs369242073	0.1540	None	gnomAD-3.1.2	2.63E-05
6216	18	V/M	28	rs369242073	0.1540	None	gnomAD-4.0.0	1.54952E-05
6217	19	E/G	29	None	0.6119	None	gnomAD-4.0.0	1.36862E-06
6218	20	L/R	30	rs727505193	0.1135	None	gnomAD-2.1.1	1.43E-05
6218	20	L/R	30	rs727505193	0.1135	None	gnomAD-3.1.2	4.6E-05
6218	20	L/R	30	rs727505193	0.1135	None	gnomAD-4.0.0	1.11563E-05
6219	21	E/D	31	rs1282711943	0.2759	None	gnomAD-2.1.1	4.03E-06
6219	21	E/D	31	rs1282711943	0.2759	None	gnomAD-4.0.0	6.84296E-07
6219	21	E/K	31	rs72648948	0.2759	None	gnomAD-2.1.1	5.72E-05
6219	21	E/K	31	rs72648948	0.2759	None	gnomAD-3.1.2	2.16917E-04
6219	21	E/K	31	rs72648948	0.2759	None	gnomAD-4.0.0	3.03693E-05
6219	21	E/Q	31	rs72648948	0.2759	None	gnomAD-2.1.1	3.19E-05
6219	21	E/Q	31	rs72648948	0.2759	None	gnomAD-3.1.2	1.97E-05
6219	21	E/Q	31	rs72648948	0.2759	None	gnomAD-4.0.0	3.71869E-06
6219	21	E/V	31	rs2080005563	0.2759	None	gnomAD-4.0.0	1.59174E-06
6220	22	C/G	33	rs935844203	0.0786	None	gnomAD-4.0.0	6.84301E-07
6220	22	C/R	33	None	0.0786	None	gnomAD-4.0.0	1.3686E-06
6220	22	C/S	33	rs191692293	0.0786	None	gnomAD-2.1.1	5.28881E-04
6220	22	C/S	33	rs191692293	0.0786	None	gnomAD-3.1.2	1.72212E-03
6220	22	C/S	33	rs191692293	0.0786	None	1000 genomes	1.99681E-03
6220	22	C/S	33	rs191692293	0.0786	None	gnomAD-4.0.0	6.84301E-07
6220	22	C/Y	33	rs191692293	0.0786	None	gnomAD-4.0.0	6.84301E-07
6221	23	E/D	34	rs369544339	0.2177	None	gnomAD-2.1.1	8.58E-05
6221	23	E/D	34	rs369544339	0.2177	None	gnomAD-3.1.2	1.05162E-04
6221	23	E/D	34	rs369544339	0.2177	None	1000 genomes	1.99681E-04
6221	23	E/D	34	rs369544339	0.2177	None	gnomAD-4.0.0	1.11549E-04
6221	23	E/G	34	rs1365356147	0.2177	None	gnomAD-4.0.0	1.5917E-06
6222	24	V/A	35	None	0.0794	None	gnomAD-4.0.0	1.20032E-06
6223	25	T/M	38	rs794727817	0.4167	None	gnomAD-2.1.1	8.05E-06
6223	25	T/M	38	rs794727817	0.4167	None	gnomAD-4.0.0	1.50547E-05
6224	26	G/E	40	rs1168353457	0.3049	None	gnomAD-2.1.1	8.05E-06
6224	26	G/E	40	rs1168353457	0.3049	None	gnomAD-4.0.0	1.59173E-06
6224	26	G/R	40	rs2154307306	0.3049	None	gnomAD-4.0.0	1.59172E-06
6225	27	T/A	41	rs794727818	0.7228	None	gnomAD-4.0.0	1.36859E-06
6225	27	T/K	41	None	0.7228	None	gnomAD-4.0.0	1.59172E-06
6225	27	T/S	41	None	0.7228	None	gnomAD-4.0.0	6.84296E-07
6226	28	P/H	42	rs746345160	0.4331	None	gnomAD-3.1.2	1.97E-05
6226	28	P/H	42	rs746345160	0.4331	None	gnomAD-4.0.0	1.9728E-05
6226	28	P/L	42	rs746345160	0.4331	None	gnomAD-2.1.1	8.05E-06
6226	28	P/L	42	rs746345160	0.4331	None	gnomAD-3.1.2	6.58E-06
6226	28	P/L	42	rs746345160	0.4331	None	gnomAD-4.0.0	8.05745E-06
6226	28	P/S	42	rs1466849790	0.4331	None	gnomAD-2.1.1	4.02E-06
6226	28	P/S	42	rs1466849790	0.4331	None	gnomAD-4.0.0	2.05288E-06
6226	28	P/T	42	rs1466849790	0.4331	None	gnomAD-4.0.0	6.84292E-07
6227	29	P/L	43	rs376846228	0.7829	None	gnomAD-2.1.1	1.43E-05
6227	29	P/L	43	rs376846228	0.7829	None	gnomAD-3.1.2	3.29E-05
6227	29	P/L	43	rs376846228	0.7829	None	gnomAD-4.0.0	8.05746E-06
6228	30	F/S	44	rs1192303175	0.1818	None	gnomAD-2.1.1	4.03E-06
6228	30	F/S	44	rs1192303175	0.1818	None	gnomAD-4.0.0	1.59172E-06
6229	31	E/D	45	rs376583582	0.7206	None	gnomAD-3.1.2	1.31E-05
6229	31	E/D	45	rs376583582	0.7206	None	gnomAD-4.0.0	3.84422E-06
6229	31	E/G	45	None	0.7206	None	gnomAD-4.0.0	1.36858E-06
6230	32	V/I	46	None	0.2701	None	gnomAD-4.0.0	1.20032E-06
6231	33	T/A	47	None	0.3965	None	gnomAD-4.0.0	1.36857E-06
6233	35	L/P	49	None	0.1959	None	gnomAD-4.0.0	1.20032E-06
6234	36	K/Q	50	None	0.1319	None	gnomAD-4.0.0	1.59168E-06
6235	37	N/K	51	rs766055257	0.4855	None	gnomAD-2.1.1	4.03E-06
6235	37	N/K	51	rs766055257	0.4855	None	gnomAD-3.1.2	6.58E-06
6235	37	N/K	51	rs766055257	0.4855	None	gnomAD-4.0.0	3.71877E-06
6235	37	N/S	51	rs2079993234	0.4855	None	gnomAD-3.1.2	6.57E-06
6235	37	N/S	51	rs2079993234	0.4855	None	gnomAD-4.0.0	2.56265E-06
6235	37	N/Y	51	None	0.4855	None	gnomAD-4.0.0	2.05287E-06
6236	38	N/D	52	rs758455641	0.9121	None	gnomAD-2.1.1	2.01E-05
6236	38	N/D	52	rs758455641	0.9121	None	gnomAD-3.1.2	6.57E-06
6236	38	N/D	52	rs758455641	0.9121	None	gnomAD-4.0.0	1.02511E-05
6237	39	R/G	55	None	0.7424	None	gnomAD-4.0.0	1.59166E-06
6237	39	R/W	55	rs750368911	0.7424	None	gnomAD-2.1.1	1.21E-05
6237	39	R/W	55	rs750368911	0.7424	None	gnomAD-4.0.0	6.36663E-06
6239	41	I/M	58	None	0.1349	None	gnomAD-4.0.0	1.59165E-06
6239	41	I/S	58	rs1221710663	0.1349	None	gnomAD-2.1.1	4.03E-06
6239	41	I/S	58	rs1221710663	0.1349	None	gnomAD-4.0.0	1.59163E-06
6240	42	R/L	59	rs761993856	0.7347	None	gnomAD-2.1.1	4.03E-06
6240	42	R/L	59	rs761993856	0.7347	None	gnomAD-4.0.0	6.84279E-07
6240	42	R/Q	59	rs761993856	0.7347	None	gnomAD-2.1.1	1.32317E-04
6240	42	R/Q	59	rs761993856	0.7347	None	gnomAD-3.1.2	3.29E-05
6240	42	R/Q	59	rs761993856	0.7347	None	gnomAD-4.0.0	4.21451E-05
6241	43	S/G	70	None	0.4999	None	gnomAD-4.0.0	1.20032E-06
6241	43	S/N	70	None	0.4999	None	gnomAD-4.0.0	1.20032E-06
6241	43	S/R	70	rs1015857991	0.4999	None	gnomAD-2.1.1	4.03E-06
6241	43	S/R	70	rs1015857991	0.4999	None	gnomAD-3.1.2	6.58E-06
6241	43	S/R	70	rs1015857991	0.4999	None	gnomAD-4.0.0	4.33843E-06
6242	44	S/G	73	None	0.2804	None	gnomAD-4.0.0	2.40064E-06
6243	45	K/E	102	rs764402049	1.0800	None	gnomAD-2.1.1	4.03E-06
6243	45	K/E	102	rs764402049	1.0800	None	gnomAD-3.1.2	6.57E-06
6243	45	K/E	102	rs764402049	1.0800	None	gnomAD-4.0.0	5.12524E-06
6244	46	K/E	115	None	0.1629	None	gnomAD-4.0.0	1.20032E-06
6244	46	K/N	115	None	0.1629	None	gnomAD-4.0.0	1.5916E-06
6244	46	K/R	115	rs1448766260	0.1629	None	gnomAD-2.1.1	4.03E-06
6244	46	K/R	115	rs1448766260	0.1629	None	gnomAD-4.0.0	1.5916E-06
6246	48	T/A	122	rs1553920950	0.4610	None	gnomAD-4.0.0	3.60097E-06
6246	48	T/I	122	rs1252010867	0.4610	None	gnomAD-2.1.1	3.19E-05
6246	48	T/I	122	rs1252010867	0.4610	None	gnomAD-3.1.2	1.31E-05
6246	48	T/I	122	rs1252010867	0.4610	None	gnomAD-4.0.0	9.13489E-06
6247	49	L/W	123	rs2079986312	0.3322	None	gnomAD-3.1.2	6.57E-06
6247	49	L/W	123	rs2079986312	0.3322	None	gnomAD-4.0.0	2.56276E-06
6249	51	D/E	127	rs774843545	0.8463	None	gnomAD-2.1.1	2.02E-05
6249	51	D/E	127	rs774843545	0.8463	None	gnomAD-4.0.0	3.42138E-06
6249	51	D/N	127	rs201263441	0.8463	None	gnomAD-2.1.1	3.722E-04
6249	51	D/N	127	rs201263441	0.8463	None	gnomAD-3.1.2	2.10396E-04
6249	51	D/N	127	rs201263441	0.8463	None	gnomAD-4.0.0	1.87172E-04
6250	52	R/K	130	rs952849958	0.7891	None	gnomAD-2.1.1	4.03E-06
6250	52	R/K	130	rs952849958	0.7891	None	gnomAD-3.1.2	6.57E-06
6250	52	R/K	130	rs952849958	0.7891	None	gnomAD-4.0.0	4.95807E-06
6253	55	V/G	135	rs1236936612	0.1791	None	gnomAD-2.1.1	4.03E-06
6253	55	V/G	135	rs1236936612	0.1791	None	gnomAD-4.0.0	1.59159E-06
6253	55	V/L	135	rs754852812	0.1791	None	gnomAD-4.0.0	2.25809E-05
6255	57	N/D	137	rs2079983036	0.2104	None	gnomAD-3.1.2	6.57E-06
6255	57	N/D	137	rs2079983036	0.2104	None	gnomAD-4.0.0	2.5627E-06
6255	57	N/K	137	None	0.2104	None	gnomAD-4.0.0	6.8428E-07
6256	58	L/F	138	rs747713653	0.0746	None	gnomAD-3.1.2	6.58E-06
6256	58	L/F	138	rs747713653	0.0746	None	gnomAD-4.0.0	1.85934E-06
6256	58	L/I	138	rs747713653	0.0746	None	gnomAD-2.1.1	4.03E-06
6256	58	L/I	138	rs747713653	0.0746	None	gnomAD-4.0.0	6.84281E-07
6256	58	L/R	138	rs780526976	0.0746	None	gnomAD-2.1.1	3.58E-05
6256	58	L/R	138	rs780526976	0.0746	None	gnomAD-3.1.2	1.97E-05
6256	58	L/R	138	rs780526976	0.0746	None	gnomAD-4.0.0	4.74189E-05
6257	59	H/R	139	rs371299041	0.3089	None	gnomAD-2.1.1	1.07E-05
6257	59	H/R	139	rs371299041	0.3089	None	gnomAD-3.1.2	1.31E-05
6257	59	H/R	139	rs371299041	0.3089	None	gnomAD-4.0.0	1.17755E-05
6257	59	H/Y	139	None	0.3089	None	gnomAD-4.0.0	1.20032E-06
6258	60	I/K	140	rs746617599	0.0746	None	gnomAD-2.1.1	8.07E-06
6259	61	T/A	141	rs780049500	0.3452	None	gnomAD-2.1.1	1.00818E-04
6259	61	T/A	141	rs780049500	0.3452	None	gnomAD-3.1.2	6.57E-06
6259	61	T/A	141	rs780049500	0.3452	None	gnomAD-4.0.0	3.65663E-05
6259	61	T/N	141	rs72648949	0.3452	None	gnomAD-2.1.1	4.03E-06
6259	61	T/N	141	rs72648949	0.3452	None	gnomAD-4.0.0	6.84286E-07
6259	61	T/S	141	rs72648949	0.3452	None	gnomAD-2.1.1	3.08967E-03
6259	61	T/S	141	rs72648949	0.3452	None	gnomAD-3.1.2	2.62369E-03
6259	61	T/S	141	rs72648949	0.3452	None	1000 genomes	5.99042E-04
6259	61	T/S	141	rs72648949	0.3452	None	gnomAD-4.0.0	2.74608E-03
6260	62	K/N	143	None	0.7298	None	gnomAD-4.0.0	1.59169E-06
6260	62	K/Q	143	rs375652574	0.7298	None	gnomAD-2.1.1	2.51E-05
6260	62	K/Q	143	rs375652574	0.7298	None	gnomAD-3.1.2	4.6E-05
6260	62	K/Q	143	rs375652574	0.7298	None	gnomAD-4.0.0	5.70167E-05
6261	63	C/R	144	rs1438614038	0.1366	None	gnomAD-3.1.2	1.31E-05
6261	63	C/R	144	rs1438614038	0.1366	None	gnomAD-4.0.0	3.84435E-06
6261	63	C/Y	144	rs1060500581	0.1366	None	gnomAD-2.1.1	8.07E-06
6261	63	C/Y	144	rs1060500581	0.1366	None	gnomAD-4.0.0	4.77515E-06
6262	64	D/G	145	rs757214692	0.2312	None	gnomAD-2.1.1	1.61E-05
6262	64	D/G	145	rs757214692	0.2312	None	gnomAD-3.1.2	1.32E-05
6262	64	D/G	145	rs757214692	0.2312	None	gnomAD-4.0.0	2.56301E-05
6263	65	P/A	146	rs753985729	0.5104	None	gnomAD-4.0.0	6.843E-07
6263	65	P/L	146	None	0.5104	None	gnomAD-4.0.0	1.59172E-06
6263	65	P/S	146	rs753985729	0.5104	None	gnomAD-2.1.1	8.07E-06
6263	65	P/S	146	rs753985729	0.5104	None	gnomAD-4.0.0	2.0529E-06
6265	67	D/G	149	rs1403981596	0.1108	None	gnomAD-2.1.1	4.03E-06
6265	67	D/G	149	rs1403981596	0.1108	None	gnomAD-4.0.0	1.59169E-06
6265	67	D/H	149	rs764050491	0.1108	None	gnomAD-4.0.0	1.5917E-06
6266	68	T/A	151	rs761009610	0.3120	None	gnomAD-2.1.1	8.07E-06
6266	68	T/A	151	rs761009610	0.3120	None	gnomAD-3.1.2	1.31E-05
6266	68	T/A	151	rs761009610	0.3120	None	gnomAD-4.0.0	7.68805E-06
6266	68	T/I	151	None	0.3120	None	gnomAD-4.0.0	1.59174E-06
6268	70	E/V	153	rs1378963436	0.5405	None	gnomAD-2.1.1	4.03E-06
6268	70	E/V	153	rs1378963436	0.5405	None	gnomAD-4.0.0	1.59178E-06
6269	71	Y/C	154	None	0.1013	None	gnomAD-4.0.0	1.36863E-06
6270	72	Q/P	155	None	0.2601	None	gnomAD-4.0.0	1.59194E-06
6270	72	Q/R	155	None	0.2601	None	gnomAD-4.0.0	1.59194E-06
6271	73	C/G	156	rs2079970402	0.0639	None	gnomAD-4.0.0	1.59192E-06
6271	73	C/Y	156	None	0.0639	None	gnomAD-4.0.0	1.59205E-06
6272	74	I/L	157	rs1385000092	0.2718	None	gnomAD-2.1.1	4.03E-06
6272	74	I/L	157	rs1385000092	0.2718	None	gnomAD-4.0.0	4.77594E-06
6272	74	I/T	157	rs1274096400	0.2718	None	gnomAD-2.1.1	3.19E-05
6272	74	I/T	157	rs1274096400	0.2718	None	gnomAD-3.1.2	6.57E-06
6272	74	I/T	157	rs1274096400	0.2718	None	gnomAD-4.0.0	6.57177E-06
6272	74	I/V	157	None	0.2718	None	gnomAD-4.0.0	1.59198E-06
6273	75	V/L	158	None	0.0760	None	gnomAD-4.0.0	4.79096E-06
6274	76	S/P	159	None	0.2355	None	gnomAD-4.0.0	2.05339E-06
6275	77	N/S	161	rs184412722	0.1965	None	gnomAD-2.1.1	3.51379E-03
6275	77	N/S	161	rs184412722	0.1965	None	gnomAD-3.1.2	1.8139E-03
6275	77	N/S	161	rs184412722	0.1965	None	1000 genomes	5.99042E-03
6275	77	N/S	161	rs184412722	0.1965	None	gnomAD-4.0.0	2.22775E-03
6278	80	G/S	164	rs397517488	0.3030	None	gnomAD-2.1.1	1.79E-05
6278	80	G/S	164	rs397517488	0.3030	None	gnomAD-3.1.2	6.57E-06
6278	80	G/S	164	rs397517488	0.3030	None	gnomAD-4.0.0	1.61299E-05
6279	81	S/R	165	rs776251068	0.5723	None	gnomAD-2.1.1	8.08E-06
6279	81	S/R	165	rs776251068	0.5723	None	gnomAD-3.1.2	6.57E-06
6279	81	S/R	165	rs776251068	0.5723	None	gnomAD-4.0.0	3.85259E-06
6280	82	C/S	166	rs768034029	0.1080	None	gnomAD-2.1.1	4.05E-06
6280	82	C/S	166	rs768034029	0.1080	None	gnomAD-4.0.0	1.59696E-06
6280	82	C/Y	166	rs768034029	0.1080	None	gnomAD-3.1.2	6.57E-06
6280	82	C/Y	166	rs768034029	0.1080	None	gnomAD-4.0.0	6.57298E-06
6282	84	C/F	169	rs2079961331	0.0924	None	gnomAD-3.1.2	6.57E-06
6282	84	C/F	169	rs2079961331	0.0924	None	gnomAD-4.0.0	2.0299E-06
6282	84	C/R	169	None	0.0924	None	gnomAD-4.0.0	3.60097E-06
6283	85	S/G	171	rs779861459	0.3526	None	gnomAD-2.1.1	2.16E-05
6283	85	S/G	171	rs779861459	0.3526	None	gnomAD-3.1.2	4.6E-05
6283	85	S/G	171	rs779861459	0.3526	None	gnomAD-4.0.0	7.44794E-06
6283	85	S/I	171	None	0.3526	None	gnomAD-4.0.0	6.85547E-07
6283	85	S/N	171	rs1283369258	0.3526	None	gnomAD-4.0.0	2.05664E-06
6283	85	S/R	171	None	0.3526	None	gnomAD-4.0.0	1.37078E-06
6284	86	T/A	172	None	0.1123	None	gnomAD-4.0.0	1.20032E-06
6284	86	T/I	172	None	0.1123	None	gnomAD-4.0.0	1.59887E-06
6285	87	R/I	173	None	0.6546	None	gnomAD-4.0.0	6.85758E-07
6285	87	R/S	173	None	0.6546	None	gnomAD-4.0.0	1.59963E-06
6285	87	R/T	173	rs2079958809	0.6546	None	gnomAD-3.1.2	6.57E-06
6285	87	R/T	173	rs2079958809	0.6546	None	gnomAD-4.0.0	7.4516E-06
6286	88	V/A	174	rs372581135	0.1267	None	gnomAD-2.1.1	4.14E-06
6286	88	V/A	174	rs372581135	0.1267	None	gnomAD-4.0.0	3.24726E-06
6286	88	V/I	174	rs149131555	0.1267	None	gnomAD-2.1.1	5.87146E-04
6286	88	V/I	174	rs149131555	0.1267	None	gnomAD-3.1.2	1.77464E-03
6286	88	V/I	174	rs149131555	0.1267	None	1000 genomes	3.39457E-03
6286	88	V/I	174	rs149131555	0.1267	None	gnomAD-4.0.0	3.30432E-04
6287	89	A/T	175	None	0.1840	None	gnomAD-4.0.0	1.64281E-06
6288	90	L/Q	177	rs1381105393	0.3131	None	gnomAD-2.1.1	4.25E-06
6288	90	L/Q	177	rs1381105393	0.3131	None	gnomAD-4.0.0	3.30111E-06
6288	90	L/V	177	rs745682900	0.3131	None	gnomAD-2.1.1	4.21E-06
6288	90	L/V	177	rs745682900	0.3131	None	gnomAD-4.0.0	1.64361E-06

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
6199	1	P/A	None	0.1424	gnomAD-4.0.0	1	None	0.6681	0.6654	23.3	D	None	-1.42	0.09361	-1.682	0.742	0.621	0.396630179004	None	0.923424	0.816	0.675111477399	0.996	0.509702026844	-4.51	0.635	0.811	0.195	None	None	1.59492E-06	0	0	0	2.775E-05	None	0	0	1.59492E-06	0	0	0	None	N	None
6199	1	P/L	rs758776829	0.1424	gnomAD-4.0.0	1	None	0.8501	0.8567	29.1	D	0.257	-1.44	0.083926	-0.593	0.7611	0.6542	0.44844398541	None	0.999994	0.819	0.907606656126	0.999	0.577930688858	-5.94	0.612	0.875	0.134	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6200	2	T/I	rs1046417798	0.5409	gnomAD-4.0.0	2	None	0.0951	0.1011	18.35	N	None	-0.29	0.022169	-0.043	0.1784	-0.9153	0.0905586785575	None	1.0	0.46	0.21737058555	None	0.341508030891	-0.85	0.067	0.238	0.381	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6202	4	I/M	rs1041345186	0.4570	gnomAD-3.1.2	4	None	0.0899	0.1022	22.0	N	None	0.89	0.010679	-0.451	0.0866	-0.9515	0.0979166354652	None	1.0	0.44	0.304108284078	0.019	0.310223668814	-1.31	0.069	0.179	0.071	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	I	None
6202	4	I/M	rs1041345186	0.4570	gnomAD-4.0.0	4	None	0.0899	0.1022	22.0	N	None	0.89	0.010679	-0.451	0.0866	-0.9515	0.0979166354652	None	1.0	0.44	0.304108284078	0.019	0.310223668814	-1.31	0.069	0.179	0.071	None	None	6.57324E-06	0	0	0	0	None	0	0	6.57324E-06	1.47037E-05	0	0	None	I	None
6202	4	I/N	None	0.4570	gnomAD-4.0.0	4	None	0.1429	0.1764	24.2	N	None	0.88	0.035937	-0.335	0.1367	-0.8853	0.240167342679	None	1.0	0.493	0.687687559846	0.427	0.375543355942	-3.79	0.163	0.375	0.034	None	None	6.84698E-07	0	0	0	0	None	0	0	6.84698E-07	8.99981E-07	0	0	None	I	None
6202	4	I/T	rs1298665270	0.4570	gnomAD-2.1.1	4	None	0.1078	0.1199	23.6	N	-0.128	1.02	0.02179	-0.853	0.0738	-1.0473	0.1303486935	None	1.0	0.433	0.405150804464	0.096	0.400773346424	-2.64	0.116	0.27	0.28	None	None	8.07E-06	0	0	0	0	None	0	None	8.07E-06	0	1.78E-05	0	None	I	None
6202	4	I/T	rs1298665270	0.4570	gnomAD-3.1.2	4	None	0.1078	0.1199	23.6	N	-0.128	1.02	0.02179	-0.853	0.0738	-1.0473	0.1303486935	None	1.0	0.433	0.405150804464	0.096	0.400773346424	-2.64	0.116	0.27	0.28	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	0	4.78011E-04	None	I	None
6202	4	I/T	rs1298665270	0.4570	gnomAD-4.0.0	4	None	0.1078	0.1199	23.6	N	-0.128	1.02	0.02179	-0.853	0.0738	-1.0473	0.1303486935	None	1.0	0.433	0.405150804464	0.096	0.400773346424	-2.64	0.116	0.27	0.28	None	None	6.20091E-06	0	1.67001E-05	0	0	None	0	0	6.20091E-06	5.0884E-06	0	4.80769E-05	None	I	None
6202	4	I/V	None	0.4570	gnomAD-4.0.0	4	None	0.07	0.0748	22.3	N	None	1.03	0.010251	-0.595	0.0638	-1.0765	0.0706562436126	None	1.0	0.421	0.262175524916	None	0.283553749323	-0.43	0.066	0.115	1.0	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
6203	5	R/G	None	0.3274	gnomAD-4.0.0	5	None	0.1974	0.2419	22.5	N	None	-0.28	0.084813	-0.92	0.3321	-0.3426	0.243585634549	None	1.0	0.545	0.564503807532	0.801	0.398889064789	-3.85	0.43	0.382	0.263	None	None	1.59392E-06	0	0	0	0	None	0	0	1.59392E-06	2.86331E-06	0	0	None	I	None
6204	6	E/D	None	0.5262	gnomAD-4.0.0	7	None	0.1688	0.1933	21.7	N	None	-0.28	0.019034	-0.678	0.2508	-0.726	0.0778385254276	None	1.0	0.406	0.297718772494	0.012	0.472376585007	-1.88	0.211	0.1	0.483	None	None	6.8457E-07	0	0	0	0	None	0	0	6.8457E-07	8.99873E-07	0	0	None	N	None
6204	6	E/G	None	0.5262	gnomAD-4.0.0	7	None	0.1226	0.1378	24.1	N	None	-0.29	0.057689	-1.088	0.2456	-0.5677	0.228153966021	None	1.0	0.45	0.502815669512	0.801	0.443172901869	-4.11	0.234	0.36	0.097	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
6204	6	E/K	rs949942051	0.5262	gnomAD-4.0.0	7	None	0.0946	0.0968	23.5	N	None	-0.15	0.034536	-0.192	0.172	-0.7928	0.146591211632	None	1.0	0.588	0.346315397577	0.454	0.541893482208	-2.33	0.262	0.252	0.384	None	None	1.36917E-06	0	0	0	0	None	0	0	1.36917E-06	1.79979E-06	0	0	None	N	None
6206	8	K/N	None	0.7794	gnomAD-4.0.0	9	None	0.2032	0.2461	15.16	N	None	-0.42	0.063732	0.007	0.1931	-0.7555	0.103523069276	None	1.0	0.543	0.170165803431	0.055	0.259093344212	-2.14	0.139	0.277	0.022	None	None	6.8456E-07	0	0	0	0	None	0	0	6.8456E-07	8.99857E-07	0	0	None	I	None
6207	9	P/A	rs755803926	0.5990	gnomAD-2.1.1	11	None	0.076	0.0847	22.2	N	-0.766	0.98	0.031851	-0.519	0.1313	-0.9519	0.0972872230624	None	0.948532	0.53	0.112648838833	0.039	0.416883587837	-4.49	0.215	0.405	0.114	None	None	4.03E-06	0	0	0	0	None	3.28E-05	None	4.03E-06	0	0	0	None	N	None
6207	9	P/A	rs755803926	0.5990	gnomAD-4.0.0	11	None	0.076	0.0847	22.2	N	-0.766	0.98	0.031851	-0.519	0.1313	-0.9519	0.0972872230624	None	0.948532	0.53	0.112648838833	0.039	0.416883587837	-4.49	0.215	0.405	0.114	None	None	1.5931E-06	0	0	0	0	None	0	0	1.5931E-06	0	1.43345E-05	0	None	N	None
6207	9	P/S	None	0.5990	gnomAD-4.0.0	11	None	0.1088	0.1229	23.7	N	None	1.1	0.04041	-0.571	0.1141	-0.8977	0.313891519587	None	0.967744	0.422	0.126345400529	0.957	0.424606919289	-4.28	0.312	0.708	0.531	None	None	3.18619E-06	0	0	0	0	None	0	0	3.18619E-06	5.72439E-06	0	0	None	N	None
6208	10	V/L	rs759379332	0.2502	gnomAD-2.1.1	13	None	0.142	0.1589	16.23	N	-0.359	-0.41	0.020069	-0.563	0.176	-0.8608	0.0834121381475	None	1.0	0.485	0.284150004643	0.001	0.277270019054	-1.65	0.273	0.118	0.503	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
6208	10	V/L	rs759379332	0.2502	gnomAD-4.0.0	13	None	0.142	0.1589	16.23	N	-0.359	-0.41	0.020069	-0.563	0.176	-0.8608	0.0834121381475	None	1.0	0.485	0.284150004643	0.001	0.277270019054	-1.65	0.273	0.118	0.503	None	None	1.59263E-06	0	0	0	0	None	0	0	1.59263E-06	0	1.43357E-05	0	None	N	None
6208	10	V/M	rs759379332	0.2502	gnomAD-2.1.1	13	None	0.0975	0.0991	20.8	D	-0.393	-0.53	0.021553	-0.469	0.3623	-0.3134	0.287075476058	None	1.0	0.557	0.430579932962	0.655	0.288305997849	-1.67	0.385	0.416	0.205	None	None	1.21E-05	0	0	0	0	None	9.82E-05	None	1.21E-05	0	0	0	None	N	None
6208	10	V/M	rs759379332	0.2502	gnomAD-4.0.0	13	None	0.0975	0.0991	20.8	D	-0.393	-0.53	0.021553	-0.469	0.3623	-0.3134	0.287075476058	None	1.0	0.557	0.430579932962	0.655	0.288305997849	-1.67	0.385	0.416	0.205	None	None	1.2741E-05	0	0	0	0	None	0	0	1.2741E-05	0	1.14685E-04	0	None	N	None
6209	11	E/K	rs751253663	0.3590	gnomAD-2.1.1	14	None	0.2981	0.2587	22.5	N	0.711	-0.29	0.040301	0.323	0.4477	-0.1835	0.455546103527	None	0.774954	0.637	0.527356302626	0.998	0.530770659447	-2.43	0.404	0.583	0.27	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
6209	11	E/K	rs751253663	0.3590	gnomAD-4.0.0	14	None	0.2981	0.2587	22.5	N	0.711	-0.29	0.040301	0.323	0.4477	-0.1835	0.455546103527	None	0.774954	0.637	0.527356302626	0.998	0.530770659447	-2.43	0.404	0.583	0.27	None	None	1.59212E-06	0	0	0	0	None	0	0	1.59212E-06	0	1.43328E-05	0	None	N	None
6209	11	E/Q	rs751253663	0.3590	gnomAD-2.1.1	14	None	0.2127	0.1863	22.2	D	0.25	-0.35	0.030827	-0.02	0.4709	-0.1324	0.451869341253	None	0.735476	0.528	0.419713421852	0.999	0.444563150406	-1.83	0.355	0.675	0.157	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
6209	11	E/Q	rs751253663	0.3590	gnomAD-4.0.0	14	None	0.2127	0.1863	22.2	D	0.25	-0.35	0.030827	-0.02	0.4709	-0.1324	0.451869341253	None	0.735476	0.528	0.419713421852	0.999	0.444563150406	-1.83	0.355	0.675	0.157	None	None	1.59212E-06	0	2.28749E-05	0	0	None	0	0	1.59212E-06	0	0	0	None	N	None
6210	12	V/I	rs766360972	0.2007	gnomAD-2.1.1	16	None	0.0993	0.0986	18.49	N	-0.56	-0.47	0.032256	-0.793	0.3573	-0.326	0.141745069593	None	1.0	0.709	0.61403422888	0.63	0.381592780352	-0.6	0.265	0.491	0.594	None	None	1.07E-05	1.24059E-04	0	0	0	None	0	None	1.07E-05	0	0	0	None	N	None
6210	12	V/I	rs766360972	0.2007	gnomAD-3.1.2	16	None	0.0993	0.0986	18.49	N	-0.56	-0.47	0.032256	-0.793	0.3573	-0.326	0.141745069593	None	1.0	0.709	0.61403422888	0.63	0.381592780352	-0.6	0.265	0.491	0.594	None	None	3.29E-05	1.20639E-04	0	0	0	None	0	0	3.29E-05	0	0	0	None	N	None
6210	12	V/I	rs766360972	0.2007	gnomAD-4.0.0	16	None	0.0993	0.0986	18.49	N	-0.56	-0.47	0.032256	-0.793	0.3573	-0.326	0.141745069593	None	1.0	0.709	0.61403422888	0.63	0.381592780352	-0.6	0.265	0.491	0.594	None	None	6.08971E-06	1.04836E-04	0	0	0	None	0	0	6.08971E-06	0	0	0	None	N	None
6211	13	V/A	rs773463426	0.3832	gnomAD-2.1.1	18	None	0.227	0.2256	24.7	N	-0.57	-0.16	0.037362	-0.72	0.3816	-0.2621	0.504685203352	None	0.968699	0.417	0.698733648705	0.999	0.575488865376	-1.76	0.315	0.598	0.386	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
6211	13	V/A	rs773463426	0.3832	gnomAD-4.0.0	18	None	0.227	0.2256	24.7	N	-0.57	-0.16	0.037362	-0.72	0.3816	-0.2621	0.504685203352	None	0.968699	0.417	0.698733648705	0.999	0.575488865376	-1.76	0.315	0.598	0.386	None	None	1.59202E-06	0	2.28749E-05	0	0	None	0	0	1.59202E-06	0	0	0	None	N	None
6211	13	V/I	rs1236160546	0.3832	gnomAD-2.1.1	18	None	0.0897	0.0914	21.2	N	-0.165	-0.22	0.016652	-0.328	0.4503	-0.1617	0.420894402933	None	0.976589	0.465	0.714023348238	0.997	0.447337061167	-0.76	0.268	0.512	0.356	None	None	3.18E-05	1.14758E-04	0	0	0	None	0	None	3.18E-05	0	0	0	None	N	None
6211	13	V/I	rs1236160546	0.3832	gnomAD-3.1.2	18	None	0.0897	0.0914	21.2	N	-0.165	-0.22	0.016652	-0.328	0.4503	-0.1617	0.420894402933	None	0.976589	0.465	0.714023348238	0.997	0.447337061167	-0.76	0.268	0.512	0.356	None	None	1.31E-05	4.82E-05	0	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
6211	13	V/I	rs1236160546	0.3832	gnomAD-4.0.0	18	None	0.0897	0.0914	21.2	N	-0.165	-0.22	0.016652	-0.328	0.4503	-0.1617	0.420894402933	None	0.976589	0.465	0.714023348238	0.997	0.447337061167	-0.76	0.268	0.512	0.356	None	None	1.31447E-05	4.82462E-05	0	0	0	None	0	0	1.31447E-05	0	0	0	None	N	None
6213	15	Y/C	rs1489995255	0.5582	gnomAD-4.0.0	24	None	0.1169	0.1331	21.8	N	None	-0.23	0.023253	0.137	0.1279	-0.9341	0.105862237292	None	1.0	0.551	0.499665682712	0.008	0.393573045731	-0.93	0.123	0.37	0.185	None	None	1.59189E-06	0	0	0	0	None	0	2.41896E-04	1.59189E-06	0	0	0	None	N	None
6213	15	Y/F	rs1489995255	0.5582	gnomAD-2.1.1	24	None	0.0905	0.1005	20.5	N	0.004	-0.23	0.032998	-0.39	0.1066	-0.9693	0.076699842996	None	0.999999	0.53	0.335661160332	None	0.372573077679	-0.16	0.129	0.27	0.714	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
6213	15	Y/F	rs1489995255	0.5582	gnomAD-4.0.0	24	None	0.0905	0.1005	20.5	N	0.004	-0.23	0.032998	-0.39	0.1066	-0.9693	0.076699842996	None	0.999999	0.53	0.335661160332	None	0.372573077679	-0.16	0.129	0.27	0.714	None	None	1.59189E-06	0	0	0	0	None	0	0	1.59189E-06	0	1.43312E-05	0	None	N	None
6215	17	D/A	rs1267800654	0.4455	gnomAD-2.1.1	26	None	0.1643	0.2033	22.6	N	-0.397	0.93	0.015491	-0.509	0.1162	-0.9747	0.142842388173	None	1.0	0.548	0.254761474806	0.309	0.330958783627	-3.91	0.161	0.307	0.287	None	None	8.05E-06	6.46E-05	0	0	0	None	0	None	8.05E-06	0	8.9E-06	0	None	N	None
6215	17	D/A	rs1267800654	0.4455	gnomAD-4.0.0	26	None	0.1643	0.2033	22.6	N	-0.397	0.93	0.015491	-0.509	0.1162	-0.9747	0.142842388173	None	1.0	0.548	0.254761474806	0.309	0.330958783627	-3.91	0.161	0.307	0.287	None	None	3.18369E-06	5.66251E-05	0	0	0	None	0	0	3.18369E-06	2.85933E-06	0	0	None	N	None
6216	18	V/M	rs369242073	0.1540	gnomAD-2.1.1	28	None	0.1429	0.1754	None	N	-0.734	None	None	-0.724	None	None	None	None	None	None	None	0.999	None	None	0.273	0.665	None	None	None	8.05E-06	6.47E-05	0	0	0	None	3.27E-05	None	8.05E-06	0	0	0	None	N	None
6216	18	V/M	rs369242073	0.1540	gnomAD-3.1.2	28	None	0.1429	0.1754	None	N	-0.734	None	None	-0.724	None	None	None	None	None	None	None	0.999	None	None	0.273	0.665	None	None	None	2.63E-05	9.65E-05	0	0	0	None	0	0	2.63E-05	0	0	0	None	N	None
6216	18	V/M	rs369242073	0.1540	gnomAD-4.0.0	28	None	0.1429	0.1754	None	N	-0.734	None	None	-0.724	None	None	None	None	None	None	None	0.999	None	None	0.273	0.665	None	None	None	1.54952E-05	6.67682E-05	0	0	0	None	0	0	1.54952E-05	1.18681E-05	2.19621E-05	6.40533E-05	None	N	None
6217	19	E/G	None	0.6119	gnomAD-4.0.0	29	None	0.1214	0.1327	19.1	N	None	0.94	0.035358	-1.044	0.1292	-0.8616	0.106270047539	None	1.0	0.537	0.190952846119	0.014	0.285324215889	-3.49	0.208	0.421	0.283	None	None	1.36862E-06	0	0	0	0	None	0	0	1.36862E-06	8.99578E-07	1.15942E-05	0	None	N	None
6218	20	L/R	rs727505193	0.1135	gnomAD-2.1.1	30	None	0.9528	0.9384	None	D	-2.071	None	None	-2.169	None	None	None	None	None	None	None	0.999	None	None	0.876	0.907	None	None	None	1.43E-05	1.65453E-04	0	0	0	None	0	None	1.43E-05	0	0	0	None	N	None
6218	20	L/R	rs727505193	0.1135	gnomAD-3.1.2	30	None	0.9528	0.9384	None	D	-2.071	None	None	-2.169	None	None	None	None	None	None	None	0.999	None	None	0.876	0.907	None	None	None	4.6E-05	1.44802E-04	6.56E-05	0	0	None	0	0	4.6E-05	0	0	0	None	N	None
6218	20	L/R	rs727505193	0.1135	gnomAD-4.0.0	30	None	0.9528	0.9384	None	D	-2.071	None	None	-2.169	None	None	None	None	None	None	None	0.999	None	None	0.876	0.907	None	None	None	1.11563E-05	2.1367E-04	1.66783E-05	0	0	None	0	0	1.11563E-05	0	0	1.60123E-05	None	N	None
6219	21	E/D	rs1282711943	0.2759	gnomAD-2.1.1	31	None	0.2086	0.2585	13.62	D	-1.031	-0.33	0.086942	-1.275	0.2493	-0.7463	0.242302907298	None	1.0	0.46	0.126345400529	0.896	0.447091341019	-1.68	0.167	0.498	0.364	None	None	4.03E-06	0	0	0	5.57E-05	None	0	None	4.03E-06	0	0	0	None	N	None
6219	21	E/D	rs1282711943	0.2759	gnomAD-4.0.0	31	None	0.2086	0.2585	13.62	D	-1.031	-0.33	0.086942	-1.275	0.2493	-0.7463	0.242302907298	None	1.0	0.46	0.126345400529	0.896	0.447091341019	-1.68	0.167	0.498	0.364	None	None	6.84296E-07	0	0	0	2.52003E-05	None	0	0	6.84296E-07	0	0	0	None	N	None
6219	21	E/K	rs72648948	0.2759	gnomAD-2.1.1	31	None	0.1582	0.1705	None	N	-0.522	None	None	-0.79	None	None	None	None	None	None	None	0.896	None	None	0.178	0.496	None	None	None	5.72E-05	6.61704E-04	0	0	0	None	0	None	5.72E-05	0	0	0	None	N	None
6219	21	E/K	rs72648948	0.2759	gnomAD-3.1.2	31	None	0.1582	0.1705	None	N	-0.522	None	None	-0.79	None	None	None	None	None	None	None	0.896	None	None	0.178	0.496	None	None	None	2.16917E-04	6.99773E-04	1.96618E-04	0	0	None	0	0	2.16917E-04	0	0	4.77555E-04	None	N	None
6219	21	E/K	rs72648948	0.2759	gnomAD-4.0.0	31	None	0.1582	0.1705	None	N	-0.522	None	None	-0.79	None	None	None	None	None	None	None	0.896	None	None	0.178	0.496	None	None	None	3.03693E-05	6.00897E-04	5.00334E-05	0	0	None	0	0	3.03693E-05	0	0	1.60128E-05	None	N	None
6219	21	E/Q	rs72648948	0.2759	gnomAD-2.1.1	31	None	0.0983	0.1075	21.9	N	-0.708	-0.31	0.036073	-0.931	0.3376	-0.393	0.386643288285	None	1.0	0.549	0.37262878642	0.984	0.442760705948	-1.45	0.293	0.568	0.449	None	None	3.19E-05	1.14758E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	N	None
6219	21	E/Q	rs72648948	0.2759	gnomAD-3.1.2	31	None	0.0983	0.1075	21.9	N	-0.708	-0.31	0.036073	-0.931	0.3376	-0.393	0.386643288285	None	1.0	0.549	0.37262878642	0.984	0.442760705948	-1.45	0.293	0.568	0.449	None	None	1.97E-05	7.24E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	N	None
6219	21	E/Q	rs72648948	0.2759	gnomAD-4.0.0	31	None	0.0983	0.1075	21.9	N	-0.708	-0.31	0.036073	-0.931	0.3376	-0.393	0.386643288285	None	1.0	0.549	0.37262878642	0.984	0.442760705948	-1.45	0.293	0.568	0.449	None	None	3.71869E-06	5.34131E-05	0	0	2.22876E-05	None	0	0	3.71869E-06	0	0	1.60128E-05	None	N	None
6219	21	E/V	rs2080005563	0.2759	gnomAD-4.0.0	31	None	0.1453	0.1764	24.3	D	None	-0.4	0.058893	-0.081	0.3379	-0.3382	0.340713629443	None	1.0	0.561	0.759310620552	0.938	0.431074798107	-4.11	0.438	0.627	0.337	None	None	1.59174E-06	0	0	0	0	None	0	0	1.59174E-06	2.85927E-06	0	0	None	N	None
6220	22	C/G	rs935844203	0.0786	gnomAD-4.0.0	33	None	0.5409	0.4876	23.5	N	None	-0.01	0.024322	-1.724	0.4354	-0.0497	0.438327093	None	0.982356	0.82	0.832549399286	0.98	0.700853824615	-7.62	0.587	0.851	0.001	None	None	6.84301E-07	0	2.23714E-05	0	0	None	0	0	6.84301E-07	0	0	0	disulfide	N	None
6220	22	C/R	None	0.0786	gnomAD-4.0.0	33	None	0.9881	0.984	23.8	D	None	-0.02	0.08252	-1.594	0.6033	0.5407	0.594789730259	None	0.999999	0.852	0.873414085314	0.997	0.772321581841	-7.76	0.702	0.885	0.002	None	None	1.3686E-06	0	0	0	2.52029E-05	None	0	1.73671E-04	1.3686E-06	0	0	0	disulfide	N	None
6220	22	C/S	rs191692293	0.0786	gnomAD-2.1.1	33	None	0.7559	0.7286	22.1	N	-1.435	-0.01	0.028285	-1.989	0.3418	-0.2359	0.206089270835	None	0.969962	0.83	0.615425489776	0.659	0.720459461212	-6.38	0.563	0.624	0.005	None	None	5.28881E-04	5.70531E-03	1.98121E-04	0	0	None	3.27E-05	None	5.28881E-04	0	0	2.81136E-04	disulfide	N	None
6220	22	C/S	rs191692293	0.0786	gnomAD-3.1.2	33	None	0.7559	0.7286	22.1	N	-1.435	-0.01	0.028285	-1.989	0.3418	-0.2359	0.206089270835	None	0.969962	0.83	0.615425489776	0.659	0.720459461212	-6.38	0.563	0.624	0.005	None	None	1.72212E-03	6.17582E-03	3.93082E-04	0	0	None	0	0	1.72212E-03	0	0	0	disulfide	N	None
6220	22	C/S	rs191692293	0.0786	1000 genomes	33	None	0.7559	0.7286	22.1	N	-1.435	-0.01	0.028285	-1.989	0.3418	-0.2359	0.206089270835	None	0.969962	0.83	0.615425489776	0.659	0.720459461212	-6.38	0.563	0.624	0.005	None	None	1.99681E-03	7.6E-03	0	None	0	0	None	None	1.99681E-03	None	0	None	disulfide	N	None
6220	22	C/S	rs191692293	0.0786	gnomAD-4.0.0	33	None	0.7559	0.7286	22.1	N	-1.435	-0.01	0.028285	-1.989	0.3418	-0.2359	0.206089270835	None	0.969962	0.83	0.615425489776	0.659	0.720459461212	-6.38	0.563	0.624	0.005	None	None	6.84301E-07	0	0	0	0	None	0	0	6.84301E-07	8.9957E-07	0	0	disulfide	N	None
6220	22	C/Y	rs191692293	0.0786	gnomAD-4.0.0	33	None	0.8966	0.9142	24.1	D	None	-0.01	0.041279	-1.055	0.5887	0.3681	0.586829414914	None	0.964699	0.825	0.770718413961	0.999	0.778890728951	-6.72	0.569	0.853	0.001	None	None	6.84301E-07	0	0	0	0	None	0	0	6.84301E-07	8.9958E-07	0	0	disulfide	N	None
6221	23	E/D	rs369544339	0.2177	gnomAD-2.1.1	34	None	0.436	0.4155	20.4	D	-1.044	-0.29	0.036526	-1.446	0.2476	-0.6906	0.203981754351	None	1.0	0.387	0.24896430686	0.92	0.534995079041	-1.94	0.115	0.405	0.336	None	None	8.58E-05	4.14E-05	2.83E-05	1.06507E-03	0	None	3.27E-05	None	8.58E-05	0	6.26E-05	2.80978E-04	None	I	None
6221	23	E/D	rs369544339	0.2177	gnomAD-3.1.2	34	None	0.436	0.4155	20.4	D	-1.044	-0.29	0.036526	-1.446	0.2476	-0.6906	0.203981754351	None	1.0	0.387	0.24896430686	0.92	0.534995079041	-1.94	0.115	0.405	0.336	None	None	1.05162E-04	2.41E-05	6.55E-05	2.59815E-03	0	None	0	0	1.05162E-04	5.88E-05	2.07039E-04	0	None	I	None
6221	23	E/D	rs369544339	0.2177	1000 genomes	34	None	0.436	0.4155	20.4	D	-1.044	-0.29	0.036526	-1.446	0.2476	-0.6906	0.203981754351	None	1.0	0.387	0.24896430686	0.92	0.534995079041	-1.94	0.115	0.405	0.336	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	I	None
6221	23	E/D	rs369544339	0.2177	gnomAD-4.0.0	34	None	0.436	0.4155	20.4	D	-1.044	-0.29	0.036526	-1.446	0.2476	-0.6906	0.203981754351	None	1.0	0.387	0.24896430686	0.92	0.534995079041	-1.94	0.115	0.405	0.336	None	None	1.11549E-04	1.33305E-05	6.668E-05	1.6563E-03	0	None	0	0	1.11549E-04	9.15529E-05	4.39174E-05	2.24086E-04	None	I	None
6221	23	E/G	rs1365356147	0.2177	gnomAD-4.0.0	34	None	0.4572	0.4215	23.7	N	-1.39	-0.34	0.043358	-1.677	0.3817	-0.1873	0.315047406336	None	1.0	0.484	0.527660502957	0.959	0.498829603195	-4.16	0.355	0.552	0.18	None	None	1.5917E-06	0	2.28739E-05	0	0	None	0	0	1.5917E-06	0	0	0	None	I	None
6222	24	V/A	None	0.0794	gnomAD-4.0.0	35	None	0.4316	0.4627	24.2	N	None	-0.76	0.024942	-1.73	0.4592	-0.0568	0.42778093366	None	0.616722	0.615	0.689150956925	0.994	0.583303391933	-2.54	0.537	0.655	0.011	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6223	25	T/M	rs794727817	0.4167	gnomAD-2.1.1	38	None	0.0727	0.0744	9.309	D	-0.231	-0.35	0.015593	-0.085	0.2061	-0.8512	0.0873067246891	None	1.0	0.507	0.437634105008	0.004	0.22018006444	-0.87	0.111	0.18	0.223	None	None	8.05E-06	0	0	0	0	None	3.27E-05	None	8.05E-06	0	8.9E-06	0	None	N	None
6223	25	T/M	rs794727817	0.4167	gnomAD-4.0.0	38	None	0.0727	0.0744	9.309	D	-0.231	-0.35	0.015593	-0.085	0.2061	-0.8512	0.0873067246891	None	1.0	0.507	0.437634105008	0.004	0.22018006444	-0.87	0.111	0.18	0.223	None	None	1.50547E-05	0	0	0	2.52042E-05	None	0	0	1.50547E-05	1.70918E-05	2.31889E-05	0	None	N	None
6224	26	G/E	rs1168353457	0.3049	gnomAD-2.1.1	40	None	0.9803	0.9857	23.0	D	-0.565	-1.14	0.052246	-0.619	0.7571	0.7026	0.526218639335	None	0.999788	0.861	0.800560755456	1.0	0.639604151249	-4.56	0.7	0.777	0.07	None	None	8.05E-06	0	0	0	5.57E-05	None	0	None	8.05E-06	0	8.9E-06	0	None	I	None
6224	26	G/E	rs1168353457	0.3049	gnomAD-4.0.0	40	None	0.9803	0.9857	23.0	D	-0.565	-1.14	0.052246	-0.619	0.7571	0.7026	0.526218639335	None	0.999788	0.861	0.800560755456	1.0	0.639604151249	-4.56	0.7	0.777	0.07	None	None	1.59173E-06	0	0	0	0	None	0	0	1.59173E-06	2.85927E-06	0	0	None	I	None
6224	26	G/R	rs2154307306	0.3049	gnomAD-4.0.0	40	None	0.9734	0.9795	22.5	D	None	-1.32	0.065119	-0.599	0.783	0.7425	0.506463245118	None	0.99981	0.864	0.859625135514	1.0	0.647370100021	-4.43	0.715	0.778	0.189	None	None	1.59172E-06	0	0	0	0	None	0	0	1.59172E-06	2.85925E-06	0	0	None	I	None
6225	27	T/A	rs794727818	0.7228	gnomAD-4.0.0	41	None	0.2609	0.2835	22.0	D	None	-0.24	0.014792	-0.405	0.3793	-0.246	0.339110008276	None	1.0	0.415	0.32471235697	0.948	0.498509824276	-2.71	0.224	0.528	0.556	None	None	1.36859E-06	0	0	0	0	None	0	0	1.36859E-06	0	0	3.31356E-05	None	I	None
6225	27	T/K	None	0.7228	gnomAD-4.0.0	41	None	0.4916	0.5687	24.7	N	None	-0.22	0.017913	-0.409	0.4069	-0.2493	0.481685419903	None	0.984668	0.529	0.589254406313	0.997	0.5649497509	-2.96	0.363	0.612	0.345	None	None	1.59172E-06	0	0	0	0	None	0	2.41663E-04	1.59172E-06	0	0	0	None	I	None
6225	27	T/S	None	0.7228	gnomAD-4.0.0	41	None	0.1777	0.1839	18.64	N	None	-0.23	0.021246	-0.504	0.1857	-0.6815	0.154875028943	None	1.0	0.386	0.234412748748	0.775	0.503211557865	-1.93	0.127	0.28	0.499	None	None	6.84296E-07	0	0	0	0	None	0	0	6.84296E-07	8.99575E-07	0	0	None	I	None
6226	28	P/H	rs746345160	0.4331	gnomAD-3.1.2	42	None	0.1548	0.1611	None	D	None	None	None	-0.139	None	None	None	None	None	None	None	0.295	None	None	0.539	0.547	None	None	None	1.97E-05	7.25E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	I	None
6226	28	P/H	rs746345160	0.4331	gnomAD-4.0.0	42	None	0.1548	0.1611	None	D	None	None	None	-0.139	None	None	None	None	None	None	None	0.295	None	None	0.539	0.547	None	None	None	1.9728E-05	7.24673E-05	0	0	0	None	0	0	1.9728E-05	0	0	0	None	I	None
6226	28	P/L	rs746345160	0.4331	gnomAD-2.1.1	42	None	0.1008	0.1001	None	D	-0.045	None	None	-0.297	None	None	None	None	None	None	None	0.012	None	None	0.388	0.427	None	None	None	8.05E-06	0	0	0	0	None	0	None	8.05E-06	0	1.78E-05	0	None	I	None
6226	28	P/L	rs746345160	0.4331	gnomAD-3.1.2	42	None	0.1008	0.1001	None	D	-0.045	None	None	-0.297	None	None	None	None	None	None	None	0.012	None	None	0.388	0.427	None	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
6226	28	P/L	rs746345160	0.4331	gnomAD-4.0.0	42	None	0.1008	0.1001	None	D	-0.045	None	None	-0.297	None	None	None	None	None	None	None	0.012	None	None	0.388	0.427	None	None	None	8.05745E-06	0	0	0	0	None	0	3.29272E-04	8.05745E-06	8.47722E-06	0	1.60138E-05	None	I	None
6226	28	P/S	rs1466849790	0.4331	gnomAD-2.1.1	42	None	0.0746	0.0841	None	N	-0.599	None	None	-0.694	None	None	None	None	None	None	None	None	None	None	0.32	0.139	None	None	None	4.02E-06	6.46E-05	0	0	0	None	0	None	4.02E-06	0	0	0	None	I	None
6226	28	P/S	rs1466849790	0.4331	gnomAD-4.0.0	42	None	0.0746	0.0841	None	N	-0.599	None	None	-0.694	None	None	None	None	None	None	None	None	None	None	0.32	0.139	None	None	None	2.05288E-06	8.96807E-05	0	0	0	None	0	0	2.05288E-06	0	0	0	None	I	None
6226	28	P/T	rs1466849790	0.4331	gnomAD-4.0.0	42	None	0.0895	0.0977	0.849	D	None	-0.83	0.034337	-0.677	0.2751	-0.7009	0.0939781848297	None	0.999885	0.831	0.0401082797425	None	0.231213107705	-0.82	0.33	0.188	0.21	None	None	6.84292E-07	0	0	0	0	None	0	0	6.84292E-07	8.9957E-07	0	0	None	I	None
6227	29	P/L	rs376846228	0.7829	gnomAD-2.1.1	43	None	0.1889	0.2001	None	N	0.123	None	None	-0.3	None	None	None	None	None	None	None	1.0	None	None	0.462	0.685	None	None	None	1.43E-05	4.13E-05	0	0	0	None	3.27E-05	None	1.43E-05	0	1.57E-05	0	None	I	None
6227	29	P/L	rs376846228	0.7829	gnomAD-3.1.2	43	None	0.1889	0.2001	None	N	0.123	None	None	-0.3	None	None	None	None	None	None	None	1.0	None	None	0.462	0.685	None	None	None	3.29E-05	7.24E-05	0	0	0	None	0	0	3.29E-05	2.94E-05	0	0	None	I	None
6227	29	P/L	rs376846228	0.7829	gnomAD-4.0.0	43	None	0.1889	0.2001	None	N	0.123	None	None	-0.3	None	None	None	None	None	None	None	1.0	None	None	0.462	0.685	None	None	None	8.05746E-06	6.67931E-05	0	3.38021E-05	0	None	0	0	8.05746E-06	4.23857E-06	1.09794E-05	1.60128E-05	None	I	None
6228	30	F/S	rs1192303175	0.1818	gnomAD-2.1.1	44	None	0.652	0.742	27.2	N	-2.888	-0.22	0.045853	-2.792	0.4098	-0.1677	0.552112428624	None	0.557551	0.487	0.784914850903	0.991	0.646142542362	-3.89	0.495	0.705	0.399	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
6228	30	F/S	rs1192303175	0.1818	gnomAD-4.0.0	44	None	0.652	0.742	27.2	N	-2.888	-0.22	0.045853	-2.792	0.4098	-0.1677	0.552112428624	None	0.557551	0.487	0.784914850903	0.991	0.646142542362	-3.89	0.495	0.705	0.399	None	None	1.59172E-06	0	2.28739E-05	0	0	None	0	0	1.59172E-06	0	0	0	None	N	None
6229	31	E/D	rs376583582	0.7206	gnomAD-3.1.2	45	None	0.1297	0.14	21.9	N	None	-0.31	0.024661	-0.34	0.2535	-0.6145	0.121918924948	None	1.0	0.422	0.258779203287	0.22	0.452845096588	-1.55	0.115	0.581	0.341	None	None	1.31E-05	4.83E-05	0	0	0	None	0	0	1.31E-05	0	0	0	None	I	None
6229	31	E/D	rs376583582	0.7206	gnomAD-4.0.0	45	None	0.1297	0.14	21.9	N	None	-0.31	0.024661	-0.34	0.2535	-0.6145	0.121918924948	None	1.0	0.422	0.258779203287	0.22	0.452845096588	-1.55	0.115	0.581	0.341	None	None	3.84422E-06	5.07546E-05	0	0	0	None	0	0	3.84422E-06	0	0	0	None	I	None
6229	31	E/G	None	0.7206	gnomAD-4.0.0	45	None	0.1819	0.1962	25.0	N	None	-0.39	0.062607	-0.467	0.4031	-0.247	0.193963078417	None	0.704353	0.476	0.501810158561	0.22	0.420505344868	-4.16	0.468	0.602	0.16	None	None	1.36858E-06	0	0	0	0	None	0	0	1.36858E-06	0	0	3.31367E-05	None	I	None
6230	32	V/I	None	0.2701	gnomAD-4.0.0	46	None	0.0934	0.1009	21.7	N	None	-0.64	0.020424	-0.566	0.2258	-0.6328	0.111877660239	None	1.0	0.617	0.532986417303	0.543	0.449333071709	-0.61	0.217	0.203	0.519	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6231	33	T/A	None	0.3965	gnomAD-4.0.0	47	None	0.0864	0.0917	21.7	N	None	-0.28	0.026674	-0.747	0.3538	-0.3858	0.12495270151	None	1.0	0.446	0.252681307341	0.174	0.39087164402	-2.31	0.26	0.523	0.621	None	None	1.36857E-06	0	0	0	0	None	0	0	1.36857E-06	1.79913E-06	0	0	None	N	None
6233	35	L/P	None	0.1959	gnomAD-4.0.0	49	None	0.9814	0.9802	25.0	N	None	0.85	0.035905	-1.491	0.2738	-0.3657	0.409156735794	None	0.995796	0.676	0.76439084235	0.966	0.537050485611	-4.01	0.377	0.654	0.018	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6234	36	K/Q	None	0.1319	gnomAD-4.0.0	50	None	0.3664	0.4278	23.6	N	None	0.58	0.041435	-1.103	0.3698	-0.1559	0.227242799613	None	1.0	0.722	0.184867976434	0.468	0.345990300179	-2.56	0.391	0.659	0.07	None	None	1.59168E-06	0	0	0	2.77362E-05	None	0	0	1.59168E-06	0	0	0	None	N	None
6235	37	N/K	rs766055257	0.4855	gnomAD-2.1.1	51	None	0.5272	0.5169	23.6	N	0.35	0.75	0.029684	-0.192	0.1802	-0.8004	0.321685474039	None	1.0	0.702	0.134241683229	0.92	0.542640686035	-3.7	0.229	0.331	0.204	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
6235	37	N/K	rs766055257	0.4855	gnomAD-3.1.2	51	None	0.5272	0.5169	23.6	N	0.35	0.75	0.029684	-0.192	0.1802	-0.8004	0.321685474039	None	1.0	0.702	0.134241683229	0.92	0.542640686035	-3.7	0.229	0.331	0.204	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
6235	37	N/K	rs766055257	0.4855	gnomAD-4.0.0	51	None	0.5272	0.5169	23.6	N	0.35	0.75	0.029684	-0.192	0.1802	-0.8004	0.321685474039	None	1.0	0.702	0.134241683229	0.92	0.542640686035	-3.7	0.229	0.331	0.204	None	None	3.71877E-06	0	0	0	0	None	0	0	3.71877E-06	4.23866E-06	0	1.60133E-05	None	N	None
6235	37	N/S	rs2079993234	0.4855	gnomAD-3.1.2	51	None	0.1409	0.1461	23.9	N	None	0.74	0.026135	-0.523	0.1824	-0.7493	0.167473837153	None	1.0	0.55	0.158396225186	0.704	0.462101638317	-2.9	0.224	0.381	0.107	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
6235	37	N/S	rs2079993234	0.4855	gnomAD-4.0.0	51	None	0.1409	0.1461	23.9	N	None	0.74	0.026135	-0.523	0.1824	-0.7493	0.167473837153	None	1.0	0.55	0.158396225186	0.704	0.462101638317	-2.9	0.224	0.381	0.107	None	None	2.56265E-06	0	0	0	0	None	0	0	2.56265E-06	4.78758E-06	0	0	None	N	None
6235	37	N/Y	None	0.4855	gnomAD-4.0.0	51	None	0.2743	0.2851	23.9	N	None	0.68	0.051594	-0.388	0.3795	-0.0675	0.470851209318	None	0.582672	0.611	0.517655672	0.996	0.517475366592	-5.03	0.41	0.442	0.009	None	None	2.05287E-06	0	0	0	0	None	0	0	2.05287E-06	0	3.47802E-05	0	None	N	None
6236	38	N/D	rs758455641	0.9121	gnomAD-2.1.1	52	None	0.1268	0.1338	23.2	N	0.43	1.06	0.015602	0.212	0.0987	-0.9956	0.188489132939	None	1.0	0.699	0.0954503805726	0.642	0.474813044071	-2.79	0.161	0.333	0.377	None	None	2.01E-05	0	0	0	0	None	0	None	2.01E-05	4.64E-05	3.56E-05	0	None	N	None
6236	38	N/D	rs758455641	0.9121	gnomAD-3.1.2	52	None	0.1268	0.1338	23.2	N	0.43	1.06	0.015602	0.212	0.0987	-0.9956	0.188489132939	None	1.0	0.699	0.0954503805726	0.642	0.474813044071	-2.79	0.161	0.333	0.377	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
6236	38	N/D	rs758455641	0.9121	gnomAD-4.0.0	52	None	0.1268	0.1338	23.2	N	0.43	1.06	0.015602	0.212	0.0987	-0.9956	0.188489132939	None	1.0	0.699	0.0954503805726	0.642	0.474813044071	-2.79	0.161	0.333	0.377	None	None	1.02511E-05	0	0	0	0	None	1.56868E-05	0	1.02511E-05	1.43631E-05	0	2.84463E-05	None	N	None
6237	39	R/G	None	0.7424	gnomAD-4.0.0	55	None	0.2128	0.2127	23.5	N	None	-0.27	0.075958	-0.105	0.218	-0.7924	0.111640583288	None	0.637254	0.502	0.480574121323	0.005	0.315321564674	-2.79	0.201	0.301	0.111	None	None	1.59166E-06	0	0	0	0	None	1.88239E-05	0	1.59166E-06	0	0	0	None	N	None
6237	39	R/W	rs750368911	0.7424	gnomAD-2.1.1	55	None	0.2347	0.2275	26.1	N	-0.279	-0.31	0.082307	-0.213	0.3846	-0.2033	0.280972310988	None	0.602093	0.568	0.450733807028	0.828	0.333911806345	-3.45	0.409	0.277	0.005	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.67E-05	0	None	N	None
6237	39	R/W	rs750368911	0.7424	gnomAD-4.0.0	55	None	0.2347	0.2275	26.1	N	-0.279	-0.31	0.082307	-0.213	0.3846	-0.2033	0.280972310988	None	0.602093	0.568	0.450733807028	0.828	0.333911806345	-3.45	0.409	0.277	0.005	None	None	6.36663E-06	0	0	0	0	None	0	0	6.36663E-06	1.1437E-05	0	0	None	N	None
6239	41	I/M	None	0.1349	gnomAD-4.0.0	58	None	0.1576	0.1666	22.1	N	None	-0.44	0.039311	-0.637	0.2181	-0.8181	0.153150436021	None	1.0	0.473	0.41958645093	0.58	0.499612569809	-1.55	0.342	0.379	0.073	None	None	1.59165E-06	0	0	0	0	None	0	0	1.59165E-06	2.85914E-06	0	0	None	N	None
6239	41	I/S	rs1221710663	0.1349	gnomAD-2.1.1	58	None	0.9352	0.9467	27.8	D	-2.808	-0.47	0.080616	-2.864	0.58	0.3515	0.477640003054	None	0.992673	0.619	0.905720156449	0.991	0.542654514313	-3.96	0.695	0.719	0.002	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
6239	41	I/S	rs1221710663	0.1349	gnomAD-4.0.0	58	None	0.9352	0.9467	27.8	D	-2.808	-0.47	0.080616	-2.864	0.58	0.3515	0.477640003054	None	0.992673	0.619	0.905720156449	0.991	0.542654514313	-3.96	0.695	0.719	0.002	None	None	1.59163E-06	0	2.2876E-05	0	0	None	0	0	1.59163E-06	0	0	0	None	N	None
6240	42	R/L	rs761993856	0.7347	gnomAD-2.1.1	59	None	0.2506	0.2383	23.0	N	0.295	-0.32	0.034367	0.301	0.2409	-0.5608	0.198620745402	None	1.0	0.506	0.622442570095	0.837	0.375728338957	-3.58	0.243	0.373	0.154	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
6240	42	R/L	rs761993856	0.7347	gnomAD-4.0.0	59	None	0.2506	0.2383	23.0	N	0.295	-0.32	0.034367	0.301	0.2409	-0.5608	0.198620745402	None	1.0	0.506	0.622442570095	0.837	0.375728338957	-3.58	0.243	0.373	0.154	None	None	6.84279E-07	0	2.23714E-05	0	0	None	0	0	6.84279E-07	0	0	0	None	N	None
6240	42	R/Q	rs761993856	0.7347	gnomAD-2.1.1	59	None	0.1177	0.108	23.2	N	0.003	-0.25	0.025344	-0.214	0.2462	-0.5719	0.26326674649	None	1.0	0.486	0.237489013734	0.958	0.3264144063	-1.92	0.162	0.417	0.114	None	None	1.32317E-04	0	0	0	1.69127E-03	None	0	None	1.32317E-04	0	2.35E-05	1.40568E-04	None	N	None
6240	42	R/Q	rs761993856	0.7347	gnomAD-3.1.2	59	None	0.1177	0.108	23.2	N	0.003	-0.25	0.025344	-0.214	0.2462	-0.5719	0.26326674649	None	1.0	0.486	0.237489013734	0.958	0.3264144063	-1.92	0.162	0.417	0.114	None	None	3.29E-05	0	0	0	7.72798E-04	None	0	0	3.29E-05	1.47E-05	0	0	None	N	None
6240	42	R/Q	rs761993856	0.7347	gnomAD-4.0.0	59	None	0.1177	0.108	23.2	N	0.003	-0.25	0.025344	-0.214	0.2462	-0.5719	0.26326674649	None	1.0	0.486	0.237489013734	0.958	0.3264144063	-1.92	0.162	0.417	0.114	None	None	4.21451E-05	2.67058E-05	0	0	1.27045E-03	None	0	0	4.21451E-05	4.23856E-06	1.09791E-05	4.804E-05	None	N	None
6241	43	S/G	None	0.4999	gnomAD-4.0.0	70	None	0.0761	0.0799	23.2	D	None	-0.43	0.018411	-0.373	0.4175	-0.161	0.391259802463	None	1.0	0.518	0.365703291355	0.99	0.474321335554	-2.48	0.437	0.382	0.319	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6241	43	S/N	None	0.4999	gnomAD-4.0.0	70	None	0.1095	0.1113	23.9	N	None	-0.4	0.019804	-0.081	0.4038	-0.256	0.421225788431	None	1.0	0.493	0.343788945184	0.999	0.544806361198	-1.61	0.312	0.441	0.471	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6241	43	S/R	rs1015857991	0.4999	gnomAD-2.1.1	70	None	0.4141	0.3935	23.9	D	-0.018	-0.41	0.031895	-0.158	0.3755	-0.4382	0.47715267638	None	1.0	0.617	0.421427970867	0.999	0.551253199577	-2.97	0.528	0.527	0.482	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
6241	43	S/R	rs1015857991	0.4999	gnomAD-3.1.2	70	None	0.4141	0.3935	23.9	D	-0.018	-0.41	0.031895	-0.158	0.3755	-0.4382	0.47715267638	None	1.0	0.617	0.421427970867	0.999	0.551253199577	-2.97	0.528	0.527	0.482	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
6241	43	S/R	rs1015857991	0.4999	gnomAD-4.0.0	70	None	0.4141	0.3935	23.9	D	-0.018	-0.41	0.031895	-0.158	0.3755	-0.4382	0.47715267638	None	1.0	0.617	0.421427970867	0.999	0.551253199577	-2.97	0.528	0.527	0.482	None	None	4.33843E-06	4.00641E-05	0	0	0	None	0	0	4.33843E-06	3.3908E-06	0	0	None	N	None
6242	44	S/G	None	0.2804	gnomAD-4.0.0	73	None	0.0609	0.0781	23.2	N	None	0.96	0.012347	-0.591	0.0644	-1.0842	0.0768560786463	None	1.0	0.491	0.0806252709748	0.001	0.385054528713	0.61	0.106	0.237	0.699	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
6243	45	K/E	rs764402049	1.0800	gnomAD-2.1.1	102	None	0.1623	0.2492	24.3	N	-0.01	1.1	0.025702	-0.365	0.1176	-0.9602	0.304362853533	None	1.0	0.548	0.216624796971	0.959	0.538989245892	-2.11	0.176	0.275	0.609	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
6243	45	K/E	rs764402049	1.0800	gnomAD-3.1.2	102	None	0.1623	0.2492	24.3	N	-0.01	1.1	0.025702	-0.365	0.1176	-0.9602	0.304362853533	None	1.0	0.548	0.216624796971	0.959	0.538989245892	-2.11	0.176	0.275	0.609	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.06954E-04	0	None	N	None
6243	45	K/E	rs764402049	1.0800	gnomAD-4.0.0	102	None	0.1623	0.2492	24.3	N	-0.01	1.1	0.025702	-0.365	0.1176	-0.9602	0.304362853533	None	1.0	0.548	0.216624796971	0.959	0.538989245892	-2.11	0.176	0.275	0.609	None	None	5.12524E-06	0	0	0	0	None	0	0	5.12524E-06	0	5.35977E-05	0	None	N	None
6244	46	K/E	None	0.1629	gnomAD-4.0.0	115	None	0.6127	0.5939	25.1	N	None	0.9	0.018509	0.165	0.2424	-0.5979	0.486747575308	None	0.901924	0.58	0.277317399466	0.996	0.596204400063	-2.26	0.29	0.418	0.263	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6244	46	K/N	None	0.1629	gnomAD-4.0.0	115	None	0.6365	0.6185	15.36	N	None	0.93	0.034691	-0.387	0.0893	-0.6144	0.18302744963	None	1.0	0.554	0.0297737177859	0.884	0.615414738655	-2.65	0.179	0.257	0.233	None	None	1.5916E-06	0	0	0	2.77316E-05	None	0	0	1.5916E-06	0	0	0	None	N	None
6244	46	K/R	rs1448766260	0.1629	gnomAD-2.1.1	115	None	0.1138	0.1085	24.7	N	-0.378	1.25	0.013487	-0.508	0.1328	-0.9089	0.375274958935	None	0.770803	0.425	0.17258766438	0.998	0.538340508938	-1.51	0.186	0.501	0.746	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
6244	46	K/R	rs1448766260	0.1629	gnomAD-4.0.0	115	None	0.1138	0.1085	24.7	N	-0.378	1.25	0.013487	-0.508	0.1328	-0.9089	0.375274958935	None	0.770803	0.425	0.17258766438	0.998	0.538340508938	-1.51	0.186	0.501	0.746	None	None	1.5916E-06	0	0	0	0	None	0	0	1.5916E-06	0	0	3.0248E-05	None	N	None
6246	48	T/A	rs1553920950	0.4610	gnomAD-4.0.0	122	None	0.0697	0.0707	22.3	N	None	-0.21	0.023624	-1.008	0.2001	-0.8508	0.0823094008257	None	1.0	0.332	0.134241683229	None	0.28984567523	-2.39	0.12	0.102	0.639	None	None	3.60097E-06	0	0	0	0	None	0	0	3.60097E-06	3.9375E-06	0	0	None	N	None
6246	48	T/I	rs1252010867	0.4610	gnomAD-2.1.1	122	None	0.0837	0.0931	19.18	N	-0.041	-0.27	0.023577	-0.387	0.1841	-0.7413	0.0905586785575	None	0.891487	0.402	0.239305524855	0.001	0.351436913013	-3.11	0.081	0.277	0.149	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.48E-05	0	None	N	None
6246	48	T/I	rs1252010867	0.4610	gnomAD-3.1.2	122	None	0.0837	0.0931	19.18	N	-0.041	-0.27	0.023577	-0.387	0.1841	-0.7413	0.0905586785575	None	0.891487	0.402	0.239305524855	0.001	0.351436913013	-3.11	0.081	0.277	0.149	None	None	1.31E-05	0	0	0	1.92976E-04	None	0	0	1.31E-05	1.47E-05	0	0	None	N	None
6246	48	T/I	rs1252010867	0.4610	gnomAD-4.0.0	122	None	0.0837	0.0931	19.18	N	-0.041	-0.27	0.023577	-0.387	0.1841	-0.7413	0.0905586785575	None	0.891487	0.402	0.239305524855	0.001	0.351436913013	-3.11	0.081	0.277	0.149	None	None	9.13489E-06	0	0	0	1.13482E-04	None	0	0	9.13489E-06	9.63946E-06	0	0	None	N	None
6247	49	L/W	rs2079986312	0.3322	gnomAD-3.1.2	123	None	0.2032	0.213	23.6	N	None	-0.39	0.053457	-1.29	0.4034	-0.1198	0.37876829736	None	1.0	0.56	0.872719117219	0.915	0.423006176949	-3.4	0.455	0.602	0.004	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
6247	49	L/W	rs2079986312	0.3322	gnomAD-4.0.0	123	None	0.2032	0.213	23.6	N	None	-0.39	0.053457	-1.29	0.4034	-0.1198	0.37876829736	None	1.0	0.56	0.872719117219	0.915	0.423006176949	-3.4	0.455	0.602	0.004	None	None	2.56276E-06	1.69205E-05	0	0	2.42507E-05	None	0	0	2.56276E-06	0	0	0	None	N	None
6249	51	D/E	rs774843545	0.8463	gnomAD-2.1.1	127	None	0.1143	0.1418	21.4	N	-0.104	-0.16	0.007388	-0.371	0.1032	-1.0061	0.0783650798132	None	1.0	0.391	0.222439326576	None	0.358505010605	-0.35	0.066	0.247	1.0	None	None	2.02E-05	0	1.45028E-04	0	0	None	0	None	2.02E-05	0	0	0	None	N	None
6249	51	D/E	rs774843545	0.8463	gnomAD-4.0.0	127	None	0.1143	0.1418	21.4	N	-0.104	-0.16	0.007388	-0.371	0.1032	-1.0061	0.0783650798132	None	1.0	0.391	0.222439326576	None	0.358505010605	-0.35	0.066	0.247	1.0	None	None	3.42138E-06	0	1.11857E-04	0	0	None	0	0	3.42138E-06	0	0	0	None	N	None
6249	51	D/N	rs201263441	0.8463	gnomAD-2.1.1	127	None	0.0764	0.0867	None	N	-0.462	None	None	-0.502	None	None	None	None	None	None	None	0.248	None	None	0.086	0.501	None	None	None	3.722E-04	0	5.66E-05	8.6257E-03	0	None	3.27E-05	None	3.722E-04	0	6.28E-05	5.61956E-04	None	N	None
6249	51	D/N	rs201263441	0.8463	gnomAD-3.1.2	127	None	0.0764	0.0867	None	N	-0.462	None	None	-0.502	None	None	None	None	None	None	None	0.248	None	None	0.086	0.501	None	None	None	2.10396E-04	2.41E-05	6.55E-05	7.20461E-03	0	None	0	0	2.10396E-04	7.35E-05	0	0	None	N	None
6249	51	D/N	rs201263441	0.8463	gnomAD-4.0.0	127	None	0.0764	0.0867	None	N	-0.462	None	None	-0.502	None	None	None	None	None	None	None	0.248	None	None	0.086	0.501	None	None	None	1.87172E-04	1.33536E-05	5.00334E-05	7.60443E-03	0	None	0	0	1.87172E-04	3.39077E-05	2.19568E-05	4.96397E-04	None	N	None
6250	52	R/K	rs952849958	0.7891	gnomAD-2.1.1	130	None	0.0682	0.0752	16.36	N	-0.342	-0.15	0.015027	-0.149	0.0857	-1.0202	0.0844159057736	None	1.0	0.536	0.159798565429	None	0.301893174648	0.03	0.15	0.135	0.958	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
6250	52	R/K	rs952849958	0.7891	gnomAD-3.1.2	130	None	0.0682	0.0752	16.36	N	-0.342	-0.15	0.015027	-0.149	0.0857	-1.0202	0.0844159057736	None	1.0	0.536	0.159798565429	None	0.301893174648	0.03	0.15	0.135	0.958	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
6250	52	R/K	rs952849958	0.7891	gnomAD-4.0.0	130	None	0.0682	0.0752	16.36	N	-0.342	-0.15	0.015027	-0.149	0.0857	-1.0202	0.0844159057736	None	1.0	0.536	0.159798565429	None	0.301893174648	0.03	0.15	0.135	0.958	None	None	4.95807E-06	0	0	0	0	None	0	0	4.95807E-06	5.08616E-06	2.19563E-05	0	None	N	None
6253	55	V/G	rs1236936612	0.1791	gnomAD-2.1.1	135	None	0.1601	0.166	23.4	N	-2.527	-0.23	0.043432	-1.983	0.1879	-0.7114	0.191457487141	None	0.972342	0.515	0.8362503026	0.642	0.439035445452	-3.78	0.32	0.651	0.311	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
6253	55	V/G	rs1236936612	0.1791	gnomAD-4.0.0	135	None	0.1601	0.166	23.4	N	-2.527	-0.23	0.043432	-1.983	0.1879	-0.7114	0.191457487141	None	0.972342	0.515	0.8362503026	0.642	0.439035445452	-3.78	0.32	0.651	0.311	None	None	1.59159E-06	0	0	0	0	None	0	0	1.59159E-06	0	1.43271E-05	0	None	N	None
6253	55	V/L	rs754852812	0.1791	gnomAD-4.0.0	135	None	0.1146	0.1234	18.87	N	None	-0.22	0.010042	-0.813	0.1454	-0.9218	0.0829554934022	None	1.0	0.447	0.462200489575	0.002	0.498756021261	-1.66	0.104	0.183	0.687	None	None	2.25809E-05	0	0	0	0	None	0	0	2.25809E-05	2.87855E-05	0	1.65678E-05	None	N	None
6255	57	N/D	rs2079983036	0.2104	gnomAD-3.1.2	137	None	0.1202	0.1215	19.73	N	None	-0.23	0.013368	-1.749	0.141	-0.953	0.100476445194	None	0.994609	0.607	0.139678290688	0.007	0.312904775143	-1.27	0.079	0.399	0.671	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07039E-04	0	None	N	None
6255	57	N/D	rs2079983036	0.2104	gnomAD-4.0.0	137	None	0.1202	0.1215	19.73	N	None	-0.23	0.013368	-1.749	0.141	-0.953	0.100476445194	None	0.994609	0.607	0.139678290688	0.007	0.312904775143	-1.27	0.079	0.399	0.671	None	None	2.5627E-06	0	0	0	0	None	0	0	2.5627E-06	0	2.67996E-05	0	None	N	None
6255	57	N/K	None	0.2104	gnomAD-4.0.0	137	None	0.1561	0.1573	14.16	N	None	-0.16	0.008867	-0.295	0.0979	-1.0547	0.0964298064135	None	1.0	0.622	0.0716867268079	None	0.321130394936	-1.44	0.099	0.261	0.961	None	None	6.8428E-07	0	0	0	0	None	0	0	6.8428E-07	8.99552E-07	0	0	None	N	None
6256	58	L/F	rs747713653	0.0746	gnomAD-3.1.2	138	None	0.4943	0.4698	22.5	D	None	-0.67	0.023521	-1.566	0.6534	0.4405	0.482416341566	None	0.997214	0.815	0.756636443533	1.0	0.528391122818	-2.76	0.586	0.825	0.157	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
6256	58	L/F	rs747713653	0.0746	gnomAD-4.0.0	138	None	0.4943	0.4698	22.5	D	None	-0.67	0.023521	-1.566	0.6534	0.4405	0.482416341566	None	0.997214	0.815	0.756636443533	1.0	0.528391122818	-2.76	0.586	0.825	0.157	None	None	1.85934E-06	0	3.33578E-05	0	0	None	0	0	1.85934E-06	0	0	1.60133E-05	None	N	None
6256	58	L/I	rs747713653	0.0746	gnomAD-2.1.1	138	None	0.1833	0.1981	22.4	N	-0.515	-0.63	0.017568	-0.675	0.6143	0.2937	0.481209393752	None	0.974025	0.803	0.711290743721	0.999	0.533524572849	-1.35	0.537	0.667	0.041	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.94E-06	0	None	N	None
6256	58	L/I	rs747713653	0.0746	gnomAD-4.0.0	138	None	0.1833	0.1981	22.4	N	-0.515	-0.63	0.017568	-0.675	0.6143	0.2937	0.481209393752	None	0.974025	0.803	0.711290743721	0.999	0.533524572849	-1.35	0.537	0.667	0.041	None	None	6.84281E-07	0	0	0	0	None	0	0	6.84281E-07	8.99552E-07	0	0	None	N	None
6256	58	L/R	rs780526976	0.0746	gnomAD-2.1.1	138	None	0.9772	0.9711	25.6	D	-1.943	-0.75	0.068258	-2.178	0.7515	0.8332	0.559304083359	None	0.99464	0.873	0.872484263163	1.0	0.587612867355	-4.14	0.826	0.913	0.007	None	None	3.58E-05	0	0	0	0	None	0	None	3.58E-05	3.19744E-04	7.85E-06	1.40568E-04	None	N	None
6256	58	L/R	rs780526976	0.0746	gnomAD-3.1.2	138	None	0.9772	0.9711	25.6	D	-1.943	-0.75	0.068258	-2.178	0.7515	0.8332	0.559304083359	None	0.99464	0.873	0.872484263163	1.0	0.587612867355	-4.14	0.826	0.913	0.007	None	None	1.97E-05	0	0	0	0	None	2.83286E-04	0	1.97E-05	0	0	0	None	N	None
6256	58	L/R	rs780526976	0.0746	gnomAD-4.0.0	138	None	0.9772	0.9711	25.6	D	-1.943	-0.75	0.068258	-2.178	0.7515	0.8332	0.559304083359	None	0.99464	0.873	0.872484263163	1.0	0.587612867355	-4.14	0.826	0.913	0.007	None	None	4.74189E-05	0	0	0	0	None	4.08112E-04	0	4.74189E-05	2.15446E-05	0	5.69022E-05	None	N	None
6257	59	H/R	rs371299041	0.3089	gnomAD-2.1.1	139	None	0.0714	0.0674	None	N	-1.134	None	None	-1.131	None	None	None	None	None	None	None	0.007	None	None	0.112	0.404	None	None	None	1.07E-05	0	0	0	0	None	3.27E-05	None	1.07E-05	0	1.57E-05	0	None	N	None
6257	59	H/R	rs371299041	0.3089	gnomAD-3.1.2	139	None	0.0714	0.0674	None	N	-1.134	None	None	-1.131	None	None	None	None	None	None	None	0.007	None	None	0.112	0.404	None	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	2.94E-05	0	0	None	N	None
6257	59	H/R	rs371299041	0.3089	gnomAD-4.0.0	139	None	0.0714	0.0674	None	N	-1.134	None	None	-1.131	None	None	None	None	None	None	None	0.007	None	None	0.112	0.404	None	None	None	1.17755E-05	0	0	0	0	None	0	1.64582E-04	1.17755E-05	1.27155E-05	3.29337E-05	0	None	N	None
6257	59	H/Y	None	0.3089	gnomAD-4.0.0	139	None	0.0791	0.0826	16.49	N	None	-0.23	0.017737	0.312	0.2514	-0.6428	0.130589135316	None	1.0	0.465	0.286465849087	0.175	0.361454069614	-2.92	0.108	0.478	0.038	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	0	3.66327E-05	None	N	None
6258	60	I/K	rs746617599	0.0746	gnomAD-2.1.1	140	None	0.968	0.973	23.1	D	-2.194	-1.3	0.122174	-2.275	0.7109	0.7084	0.399301076883	None	0.993157	0.775	0.926597058261	0.939	0.49560213089	-4.23	0.832	0.82	0.001	None	None	8.07E-06	0	0	0	0	None	0	None	8.07E-06	0	1.79E-05	0	None	N	None
6259	61	T/A	rs780049500	0.3452	gnomAD-2.1.1	141	None	0.0669	0.0715	15.67	N	-1.061	-0.21	0.027742	-0.722	0.1724	-0.8944	0.0836977851295	None	1.0	0.441	0.158396225186	0.003	0.338856339455	-2.11	0.119	0.273	0.494	None	None	1.00818E-04	0	0	0	0	None	8.17367E-04	None	1.00818E-04	0	0	0	None	N	None
6259	61	T/A	rs780049500	0.3452	gnomAD-3.1.2	141	None	0.0669	0.0715	15.67	N	-1.061	-0.21	0.027742	-0.722	0.1724	-0.8944	0.0836977851295	None	1.0	0.441	0.158396225186	0.003	0.338856339455	-2.11	0.119	0.273	0.494	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	0	2.07039E-04	0	None	N	None
6259	61	T/A	rs780049500	0.3452	gnomAD-4.0.0	141	None	0.0669	0.0715	15.67	N	-1.061	-0.21	0.027742	-0.722	0.1724	-0.8944	0.0836977851295	None	1.0	0.441	0.158396225186	0.003	0.338856339455	-2.11	0.119	0.273	0.494	None	None	3.65663E-05	0	0	0	0	None	0	0	3.65663E-05	0	6.25796E-04	3.20246E-05	None	N	None
6259	61	T/N	rs72648949	0.3452	gnomAD-2.1.1	141	None	0.0767	0.0806	17.95	N	-1.386	-0.23	0.01163	-1.132	0.142	-0.9765	0.0956197624706	None	1.0	0.414	0.276482976112	None	0.373224079609	-1.64	0.089	0.121	0.468	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
6259	61	T/N	rs72648949	0.3452	gnomAD-4.0.0	141	None	0.0767	0.0806	17.95	N	-1.386	-0.23	0.01163	-1.132	0.142	-0.9765	0.0956197624706	None	1.0	0.414	0.276482976112	None	0.373224079609	-1.64	0.089	0.121	0.468	None	None	6.84286E-07	0	0	0	0	None	0	0	6.84286E-07	0	1.15934E-05	0	None	N	None
6259	61	T/S	rs72648949	0.3452	gnomAD-2.1.1	141	None	0.0745	0.0759	14.94	N	-1.471	-0.14	0.016337	-1.227	0.1305	-0.9776	0.0753460736105	None	1.0	0.409	0.12205267543	None	0.339321732521	-1.27	0.096	0.106	0.572	None	None	3.08967E-03	5.38302E-04	1.44394E-03	3.21172E-02	0	None	1.079E-03	None	3.08967E-03	3.59827E-04	3.11764E-03	4.07876E-03	None	N	None
6259	61	T/S	rs72648949	0.3452	gnomAD-3.1.2	141	None	0.0745	0.0759	14.94	N	-1.471	-0.14	0.016337	-1.227	0.1305	-0.9776	0.0753460736105	None	1.0	0.409	0.12205267543	None	0.339321732521	-1.27	0.096	0.106	0.572	None	None	2.62369E-03	3.13888E-04	3.92927E-03	2.76976E-02	0	None	4.71342E-04	9.49367E-03	2.62369E-03	2.9705E-03	1.44928E-03	6.2201E-03	None	N	None
6259	61	T/S	rs72648949	0.3452	1000 genomes	141	None	0.0745	0.0759	14.94	N	-1.471	-0.14	0.016337	-1.227	0.1305	-0.9776	0.0753460736105	None	1.0	0.409	0.12205267543	None	0.339321732521	-1.27	0.096	0.106	0.572	None	None	5.99042E-04	0	1.4E-03	None	0	1E-03	None	None	5.99042E-04	None	1E-03	None	None	N	None
6259	61	T/S	rs72648949	0.3452	gnomAD-4.0.0	141	None	0.0745	0.0759	14.94	N	-1.471	-0.14	0.016337	-1.227	0.1305	-0.9776	0.0753460736105	None	1.0	0.409	0.12205267543	None	0.339321732521	-1.27	0.096	0.106	0.572	None	None	2.74608E-03	6.13448E-04	2.05034E-03	3.36015E-02	0	None	3.75E-04	1.27231E-02	2.74608E-03	2.33459E-03	1.30652E-03	4.70611E-03	None	N	None
6260	62	K/N	None	0.7298	gnomAD-4.0.0	143	None	0.1938	0.2285	21.3	N	None	1.17	0.015601	0.152	0.0596	-1.0894	0.101977216938	None	1.0	0.54	0.0482279557977	0.004	0.290595322847	-2.1	0.054	0.29	0.531	None	None	1.59169E-06	0	2.28728E-05	0	0	None	0	0	1.59169E-06	0	0	0	None	N	None
6260	62	K/Q	rs375652574	0.7298	gnomAD-2.1.1	143	None	0.105	0.1121	None	N	-0.147	None	None	-0.037	None	None	None	None	None	None	None	0.638	None	None	0.132	0.462	None	None	None	2.51E-05	0	2.83E-05	0	0	None	0	None	2.51E-05	0	4.71E-05	0	None	N	None
6260	62	K/Q	rs375652574	0.7298	gnomAD-3.1.2	143	None	0.105	0.1121	None	N	-0.147	None	None	-0.037	None	None	None	None	None	None	None	0.638	None	None	0.132	0.462	None	None	None	4.6E-05	0	0	0	0	None	0	0	4.6E-05	1.0295E-04	0	0	None	N	None
6260	62	K/Q	rs375652574	0.7298	gnomAD-4.0.0	143	None	0.105	0.1121	None	N	-0.147	None	None	-0.037	None	None	None	None	None	None	None	0.638	None	None	0.132	0.462	None	None	None	5.70167E-05	0	1.6675E-05	0	0	None	0	0	5.70167E-05	7.71422E-05	0	0	None	N	None
6261	63	C/R	rs1438614038	0.1366	gnomAD-3.1.2	144	None	0.9237	0.8908	24.5	N	None	-0.23	0.038565	-1.268	0.5454	0.2186	0.615612516959	None	0.999994	0.727	0.853965696696	1.0	0.729479134083	-5.88	0.657	0.783	0.034	None	None	1.31E-05	4.83E-05	0	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
6261	63	C/R	rs1438614038	0.1366	gnomAD-4.0.0	144	None	0.9237	0.8908	24.5	N	None	-0.23	0.038565	-1.268	0.5454	0.2186	0.615612516959	None	0.999994	0.727	0.853965696696	1.0	0.729479134083	-5.88	0.657	0.783	0.034	None	None	3.84435E-06	3.38421E-05	0	0	0	None	0	0	3.84435E-06	0	0	2.84511E-05	None	N	None
6261	63	C/Y	rs1060500581	0.1366	gnomAD-2.1.1	144	None	0.6594	0.5649	23.9	N	-1.305	-0.23	0.025824	-1.216	0.5689	0.1935	0.600679684098	None	0.997456	0.496	0.799932464155	1.0	0.738686442375	-5.38	0.44	0.772	0.117	None	None	8.07E-06	0	5.8E-05	0	0	None	0	None	8.07E-06	0	0	0	None	N	None
6261	63	C/Y	rs1060500581	0.1366	gnomAD-4.0.0	144	None	0.6594	0.5649	23.9	N	-1.305	-0.23	0.025824	-1.216	0.5689	0.1935	0.600679684098	None	0.997456	0.496	0.799932464155	1.0	0.738686442375	-5.38	0.44	0.772	0.117	None	None	4.77515E-06	0	4.57457E-05	0	0	None	0	0	4.77515E-06	2.85925E-06	0	0	None	N	None
6262	64	D/G	rs757214692	0.2312	gnomAD-2.1.1	145	None	0.2837	0.308	22.9	N	-0.515	-0.27	0.058223	-0.804	0.1904	-0.8623	0.112277597435	None	1.0	0.488	0.195762928549	0.003	0.437957525253	-3.13	0.336	0.158	0.368	None	None	1.61E-05	0	0	0	2.22792E-04	None	0	None	1.61E-05	0	0	0	None	N	None
6262	64	D/G	rs757214692	0.2312	gnomAD-3.1.2	145	None	0.2837	0.308	22.9	N	-0.515	-0.27	0.058223	-0.804	0.1904	-0.8623	0.112277597435	None	1.0	0.488	0.195762928549	0.003	0.437957525253	-3.13	0.336	0.158	0.368	None	None	1.32E-05	0	0	0	3.86698E-04	None	0	0	1.32E-05	0	0	0	None	N	None
6262	64	D/G	rs757214692	0.2312	gnomAD-4.0.0	145	None	0.2837	0.308	22.9	N	-0.515	-0.27	0.058223	-0.804	0.1904	-0.8623	0.112277597435	None	1.0	0.488	0.195762928549	0.003	0.437957525253	-3.13	0.336	0.158	0.368	None	None	2.56301E-05	0	0	0	4.8506E-04	None	0	0	2.56301E-05	0	0	0	None	N	None
6263	65	P/A	rs753985729	0.5104	gnomAD-4.0.0	146	None	0.0617	0.0597	16.7	N	None	1.01	0.005985	-0.392	0.0493	-1.0422	0.0813673231391	None	1.0	0.546	0.0611884634855	0.003	0.28861194849	-3.86	0.102	0.15	0.541	None	None	6.843E-07	0	0	0	0	None	0	0	6.843E-07	8.99572E-07	0	0	None	N	None
6263	65	P/L	None	0.5104	gnomAD-4.0.0	146	None	0.0706	0.0716	19.96	N	None	1.07	0.018242	-0.207	0.0673	-1.0401	0.0935492712286	None	1.0	0.558	0.289098819767	0.101	0.326354980469	-5.07	0.077	0.249	0.243	None	None	1.59172E-06	0	0	0	0	None	0	0	1.59172E-06	2.85922E-06	0	0	None	N	None
6263	65	P/S	rs753985729	0.5104	gnomAD-2.1.1	146	None	0.0745	0.0738	17.76	N	0.116	0.97	0.015791	-0.269	0.0558	-1.0304	0.0851288450181	None	1.0	0.512	0.0666544352282	0.007	0.281881898642	-3.61	0.083	0.212	0.494	None	None	8.07E-06	0	0	0	0	None	0	None	8.07E-06	0	1.79E-05	0	None	N	None
6263	65	P/S	rs753985729	0.5104	gnomAD-4.0.0	146	None	0.0745	0.0738	17.76	N	0.116	0.97	0.015791	-0.269	0.0558	-1.0304	0.0851288450181	None	1.0	0.512	0.0666544352282	0.007	0.281881898642	-3.61	0.083	0.212	0.494	None	None	2.0529E-06	0	0	0	0	None	0	0	2.0529E-06	2.69872E-06	0	0	None	N	None
6265	67	D/G	rs1403981596	0.1108	gnomAD-2.1.1	149	None	0.926	0.9021	24.0	D	-1.004	-1.53	0.169029	0.041	0.7687	0.8539	0.377367588262	None	0.995487	0.831	0.718210980111	0.928	0.649133205414	-4.58	0.849	0.771	0.017	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
6265	67	D/G	rs1403981596	0.1108	gnomAD-4.0.0	149	None	0.926	0.9021	24.0	D	-1.004	-1.53	0.169029	0.041	0.7687	0.8539	0.377367588262	None	0.995487	0.831	0.718210980111	0.928	0.649133205414	-4.58	0.849	0.771	0.017	None	None	1.59169E-06	0	0	0	0	None	0	0	1.59169E-06	2.85915E-06	0	0	None	N	None
6265	67	D/H	rs764050491	0.1108	gnomAD-4.0.0	149	None	0.9081	0.8885	22.6	D	-0.48	-1.54	0.071262	0.533	0.7166	0.5319	0.459013093595	None	0.999446	0.831	0.711559257315	0.997	0.702606260777	-4.77	0.732	0.819	0.022	None	None	1.5917E-06	0	0	0	0	None	1.88288E-05	0	1.5917E-06	0	0	0	None	N	None
6266	68	T/A	rs761009610	0.3120	gnomAD-2.1.1	151	None	0.0637	0.0648	20.3	N	-0.714	-0.14	0.017531	-0.915	0.0818	-1.0644	0.0819550916224	None	1.0	0.396	0.0716867268079	None	0.298235803843	-1.17	0.057	0.105	0.663	None	None	8.07E-06	0	2.9E-05	0	0	None	0	None	8.07E-06	0	8.93E-06	0	None	N	None
6266	68	T/A	rs761009610	0.3120	gnomAD-3.1.2	151	None	0.0637	0.0648	20.3	N	-0.714	-0.14	0.017531	-0.915	0.0818	-1.0644	0.0819550916224	None	1.0	0.396	0.0716867268079	None	0.298235803843	-1.17	0.057	0.105	0.663	None	None	1.31E-05	0	1.30976E-04	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
6266	68	T/A	rs761009610	0.3120	gnomAD-4.0.0	151	None	0.0637	0.0648	20.3	N	-0.714	-0.14	0.017531	-0.915	0.0818	-1.0644	0.0819550916224	None	1.0	0.396	0.0716867268079	None	0.298235803843	-1.17	0.057	0.105	0.663	None	None	7.68805E-06	0	5.08595E-05	0	0	None	0	0	7.68805E-06	7.18085E-06	0	0	None	N	None
6266	68	T/I	None	0.3120	gnomAD-4.0.0	151	None	0.1029	0.1016	22.3	N	None	-0.29	0.034666	-0.382	0.1753	-0.864	0.0926214090609	None	1.0	0.45	0.290590437066	0.004	0.352445423603	-1.16	0.067	0.428	0.15	None	None	1.59174E-06	0	0	0	0	None	0	0	1.59174E-06	2.85922E-06	0	0	None	N	None
6268	70	E/V	rs1378963436	0.5405	gnomAD-2.1.1	153	None	0.1672	0.1509	24.0	N	-0.334	-0.3	0.043364	-0.219	0.2344	-0.7509	0.111437477428	None	0.835485	0.537	0.505765104075	0.015	0.438449561596	-3.82	0.355	0.423	0.235	None	None	4.03E-06	0	0	9.98E-05	0	None	0	None	4.03E-06	0	0	0	None	N	None
6268	70	E/V	rs1378963436	0.5405	gnomAD-4.0.0	153	None	0.1672	0.1509	24.0	N	-0.334	-0.3	0.043364	-0.219	0.2344	-0.7509	0.111437477428	None	0.835485	0.537	0.505765104075	0.015	0.438449561596	-3.82	0.355	0.423	0.235	None	None	1.59178E-06	0	0	4.77145E-05	0	None	0	0	1.59178E-06	0	0	0	None	N	None
6269	71	Y/C	None	0.1013	gnomAD-4.0.0	154	None	0.9473	0.967	26.2	D	None	-1.28	0.18898	-2.206	0.8213	0.9588	0.517459491388	None	0.990372	0.793	0.894440237169	1.0	0.72968429327	-5.66	0.873	0.879	0.01	None	None	1.36863E-06	0	2.23734E-05	0	0	None	0	0	1.36863E-06	8.99575E-07	0	0	None	N	None
6270	72	Q/P	None	0.2601	gnomAD-4.0.0	155	None	0.909	0.9259	25.8	N	None	0.97	0.034293	-0.073	0.3642	-0.0599	0.486201797658	None	0.757911	0.423	0.430126000877	0.999	0.498011857271	-3.31	0.378	0.621	0.241	None	None	1.59194E-06	0	0	0	0	None	0	0	1.59194E-06	2.85968E-06	0	0	None	N	None
6270	72	Q/R	None	0.2601	gnomAD-4.0.0	155	None	0.118	0.1129	25.4	N	None	1.08	0.027693	-0.325	0.234	-0.6436	0.443894212982	None	1.0	0.41	0.18274738541	0.997	0.526196539402	-2.31	0.205	0.537	0.598	None	None	1.59194E-06	0	0	0	0	None	0	0	1.59194E-06	2.85968E-06	0	0	None	N	None
6271	73	C/G	rs2079970402	0.0639	gnomAD-4.0.0	156	None	0.8136	0.7012	27.8	D	None	-0.12	0.19087	-1.856	0.642	0.6609	0.515532960109	None	0.997349	0.831	0.878498160798	1.0	0.625322341919	-7.61	0.782	0.882	0.036	None	None	1.59192E-06	0	0	0	0	None	0	0	1.59192E-06	2.85964E-06	0	0	disulfide	N	None
6271	73	C/Y	None	0.0639	gnomAD-4.0.0	156	None	0.9609	0.9359	24.2	D	None	-0.12	0.144803	-1.108	0.6636	0.6468	0.600679684098	None	0.999543	0.822	0.817822398108	1.0	0.747665524483	-6.87	0.708	0.909	0.09	None	None	1.59205E-06	0	0	0	0	None	0	2.41896E-04	1.59205E-06	0	0	0	disulfide	N	None
6272	74	I/L	rs1385000092	0.2718	gnomAD-2.1.1	157	None	0.1128	0.113	21.4	N	-0.731	-0.23	0.030565	-1.089	0.193	-0.8293	0.0954174873415	None	1.0	0.494	0.478068462777	0.08	0.392718583345	-1.09	0.162	0.361	0.826	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
6272	74	I/L	rs1385000092	0.2718	gnomAD-4.0.0	157	None	0.1128	0.113	21.4	N	-0.731	-0.23	0.030565	-1.089	0.193	-0.8293	0.0954174873415	None	1.0	0.494	0.478068462777	0.08	0.392718583345	-1.09	0.162	0.361	0.826	None	None	4.77594E-06	0	0	0	0	None	0	0	4.77594E-06	5.71948E-06	1.4332E-05	0	None	N	None
6272	74	I/T	rs1274096400	0.2718	gnomAD-2.1.1	157	None	0.1096	0.1068	23.1	N	-1.496	-0.14	0.013694	-1.806	0.1346	-0.938	0.109108561739	None	1.0	0.474	0.602402279407	0.005	0.476497769356	-2.81	0.287	0.351	0.786	None	None	3.19E-05	1.14811E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	N	None
6272	74	I/T	rs1274096400	0.2718	gnomAD-3.1.2	157	None	0.1096	0.1068	23.1	N	-1.496	-0.14	0.013694	-1.806	0.1346	-0.938	0.109108561739	None	1.0	0.474	0.602402279407	0.005	0.476497769356	-2.81	0.287	0.351	0.786	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
6272	74	I/T	rs1274096400	0.2718	gnomAD-4.0.0	157	None	0.1096	0.1068	23.1	N	-1.496	-0.14	0.013694	-1.806	0.1346	-0.938	0.109108561739	None	1.0	0.474	0.602402279407	0.005	0.476497769356	-2.81	0.287	0.351	0.786	None	None	6.57177E-06	2.41231E-05	0	0	0	None	0	0	6.57177E-06	0	0	0	None	N	None
6272	74	I/V	None	0.2718	gnomAD-4.0.0	157	None	0.07	0.0704	20.2	N	None	-0.14	0.012624	-1.375	0.1202	-0.9935	0.0708349770375	None	1.0	0.45	0.530109961917	0.001	0.333039700985	-0.55	0.078	0.218	0.719	None	None	1.59198E-06	0	0	0	0	None	0	0	1.59198E-06	2.85974E-06	0	0	None	N	None
6273	75	V/L	None	0.0760	gnomAD-4.0.0	158	None	0.2493	0.306	14.47	N	None	-0.56	0.048676	-0.058	0.2913	-0.641	0.0855303882618	None	0.949986	0.713	0.180583059064	0.004	0.366610467434	-1.27	0.201	0.481	0.222	None	None	4.79096E-06	0	0	0	0	None	0	0	4.79096E-06	6.29809E-06	0	0	None	N	None
6274	76	S/P	None	0.2355	gnomAD-4.0.0	159	None	0.8907	0.9096	14.78	N	None	-0.34	0.051324	-0.461	0.3887	-0.2474	0.256446074855	None	1.0	0.462	0.126345400529	0.497	0.412569522858	-2.4	0.353	0.523	0.193	None	None	2.05339E-06	0	0	0	0	None	0	0	2.05339E-06	1.79958E-06	1.15969E-05	0	None	N	None
6275	77	N/S	rs184412722	0.1965	gnomAD-2.1.1	161	None	0.2821	0.3469	None	N	-0.92	None	None	-0.972	None	None	None	None	None	None	None	0.362	None	None	0.286	0.306	None	None	None	3.51379E-03	2.06919E-04	7.65263E-04	1.06775E-03	1.02575E-04	None	2.2327E-02	None	3.51379E-03	4.01E-05	1.81387E-03	3.10209E-03	None	I	None
6275	77	N/S	rs184412722	0.1965	gnomAD-3.1.2	161	None	0.2821	0.3469	None	N	-0.92	None	None	-0.972	None	None	None	None	None	None	None	0.362	None	None	0.286	0.306	None	None	None	1.8139E-03	2.41255E-04	1.83366E-03	8.64553E-04	0	None	9.42E-05	0	1.8139E-03	1.69063E-03	2.37997E-02	1.91022E-03	None	I	None
6275	77	N/S	rs184412722	0.1965	1000 genomes	161	None	0.2821	0.3469	None	N	-0.92	None	None	-0.972	None	None	None	None	None	None	None	0.362	None	None	0.286	0.306	None	None	None	5.99042E-03	0	1.4E-03	None	0	3E-03	None	None	5.99042E-03	None	2.66E-02	None	None	I	None
6275	77	N/S	rs184412722	0.1965	gnomAD-4.0.0	161	None	0.2821	0.3469	None	N	-0.92	None	None	-0.972	None	None	None	None	None	None	None	0.362	None	None	0.286	0.306	None	None	None	2.22775E-03	3.19974E-04	1.00047E-03	8.45451E-04	1.56138E-04	None	7.81274E-05	3.96825E-03	2.22775E-03	1.10259E-03	2.15868E-02	2.93091E-03	None	I	None
6278	80	G/S	rs397517488	0.3030	gnomAD-2.1.1	164	None	0.452	0.4624	22.7	D	-0.083	-0.83	0.038087	-0.376	0.6765	0.4587	0.463496485926	None	0.999599	0.882	0.511105228888	1.0	0.427105903625	-3.21	0.651	0.786	0.081	None	None	1.79E-05	0	0	0	1.53846E-04	None	0	None	1.79E-05	0	7.86E-06	1.41243E-04	None	I	None
6278	80	G/S	rs397517488	0.3030	gnomAD-3.1.2	164	None	0.452	0.4624	22.7	D	-0.083	-0.83	0.038087	-0.376	0.6765	0.4587	0.463496485926	None	0.999599	0.882	0.511105228888	1.0	0.427105903625	-3.21	0.651	0.786	0.081	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	I	None
6278	80	G/S	rs397517488	0.3030	gnomAD-4.0.0	164	None	0.452	0.4624	22.7	D	-0.083	-0.83	0.038087	-0.376	0.6765	0.4587	0.463496485926	None	0.999599	0.882	0.511105228888	1.0	0.427105903625	-3.21	0.651	0.786	0.081	None	None	1.61299E-05	2.67201E-05	0	0	1.56138E-04	None	0	1.64799E-04	1.61299E-05	1.1031E-05	1.09946E-05	3.20708E-05	None	I	None
6279	81	S/R	rs776251068	0.5723	gnomAD-2.1.1	165	None	0.3415	0.3171	22.2	N	-0.002	-0.3	0.043561	-0.186	0.3254	-0.4337	0.422304540963	None	1.0	0.425	0.463328977263	0.984	0.460212051868	-2.46	0.265	0.625	0.199	None	None	8.08E-06	0	0	0	0	None	3.28E-05	None	8.08E-06	0	8.95E-06	0	None	I	None
6279	81	S/R	rs776251068	0.5723	gnomAD-3.1.2	165	None	0.3415	0.3171	22.2	N	-0.002	-0.3	0.043561	-0.186	0.3254	-0.4337	0.422304540963	None	1.0	0.425	0.463328977263	0.984	0.460212051868	-2.46	0.265	0.625	0.199	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	I	None
6279	81	S/R	rs776251068	0.5723	gnomAD-4.0.0	165	None	0.3415	0.3171	22.2	N	-0.002	-0.3	0.043561	-0.186	0.3254	-0.4337	0.422304540963	None	1.0	0.425	0.463328977263	0.984	0.460212051868	-2.46	0.265	0.625	0.199	None	None	3.85259E-06	0	0	0	0	None	0	0	3.85259E-06	4.80146E-06	1.34279E-05	0	None	I	None
6280	82	C/S	rs768034029	0.1080	gnomAD-2.1.1	166	None	0.1779	0.1817	23.3	N	-0.282	-0.14	0.032916	-0.753	0.2512	-0.4885	0.434023785993	None	0.737703	0.433	0.671445999895	0.98	0.497273564339	-4.77	0.494	0.651	0.791	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	0	8.96E-06	0	None	I	None
6280	82	C/S	rs768034029	0.1080	gnomAD-4.0.0	166	None	0.1779	0.1817	23.3	N	-0.282	-0.14	0.032916	-0.753	0.2512	-0.4885	0.434023785993	None	0.737703	0.433	0.671445999895	0.98	0.497273564339	-4.77	0.494	0.651	0.791	None	None	1.59696E-06	0	0	0	0	None	0	0	1.59696E-06	2.87082E-06	0	0	None	I	None
6280	82	C/Y	rs768034029	0.1080	gnomAD-3.1.2	166	None	0.3916	0.3784	23.6	N	None	-0.22	0.033372	-0.835	0.5207	0.0364	0.590485284922	None	0.857741	0.449	0.772397396667	0.999	0.599678337574	-5.65	0.333	0.787	0.034	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	I	None
6280	82	C/Y	rs768034029	0.1080	gnomAD-4.0.0	166	None	0.3916	0.3784	23.6	N	None	-0.22	0.033372	-0.835	0.5207	0.0364	0.590485284922	None	0.857741	0.449	0.772397396667	0.999	0.599678337574	-5.65	0.333	0.787	0.034	None	None	6.57298E-06	0	0	0	0	None	0	0	6.57298E-06	1.47029E-05	0	0	None	I	None
6282	84	C/F	rs2079961331	0.0924	gnomAD-3.1.2	169	None	0.4053	0.322	21.5	N	None	-0.26	0.044478	-1.274	0.4858	-0.1017	0.370627674417	None	1.0	0.505	0.764433835033	0.484	0.389063954353	-5.21	0.339	0.82	0.106	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
6282	84	C/F	rs2079961331	0.0924	gnomAD-4.0.0	169	None	0.4053	0.322	21.5	N	None	-0.26	0.044478	-1.274	0.4858	-0.1017	0.370627674417	None	1.0	0.505	0.764433835033	0.484	0.389063954353	-5.21	0.339	0.82	0.106	None	None	2.0299E-06	0	0	0	0	None	0	0	2.0299E-06	2.40987E-06	0	0	None	N	None
6282	84	C/R	None	0.0924	gnomAD-4.0.0	169	None	0.686	0.5382	16.75	D	None	-0.23	0.040141	-0.869	0.3314	-0.4994	0.331797430872	None	0.9779	0.629	0.649823028507	0.317	0.447935044765	-5.6	0.301	0.835	0.114	None	None	3.60097E-06	0	0	0	0	None	0	0	3.60097E-06	3.9375E-06	0	0	None	N	None
6283	85	S/G	rs779861459	0.3526	gnomAD-2.1.1	171	None	0.0831	0.0864	22.0	N	-0.852	-0.35	0.026385	-0.587	0.3302	-0.503	0.0882553721524	None	1.0	0.549	0.281780670237	0.012	0.313409149647	-2.29	0.29	0.427	0.067	None	None	2.16E-05	2.48262E-04	0	0	0	None	0	None	2.16E-05	0	0	0	None	N	None
6283	85	S/G	rs779861459	0.3526	gnomAD-3.1.2	171	None	0.0831	0.0864	22.0	N	-0.852	-0.35	0.026385	-0.587	0.3302	-0.503	0.0882553721524	None	1.0	0.549	0.281780670237	0.012	0.313409149647	-2.29	0.29	0.427	0.067	None	None	4.6E-05	1.44774E-04	0	0	0	None	0	0	4.6E-05	1.47E-05	0	0	None	N	None
6283	85	S/G	rs779861459	0.3526	gnomAD-4.0.0	171	None	0.0831	0.0864	22.0	N	-0.852	-0.35	0.026385	-0.587	0.3302	-0.503	0.0882553721524	None	1.0	0.549	0.281780670237	0.012	0.313409149647	-2.29	0.29	0.427	0.067	None	None	7.44794E-06	1.33586E-04	0	0	0	None	0	0	7.44794E-06	1.69763E-06	0	0	None	N	None
6283	85	S/I	None	0.3526	gnomAD-4.0.0	171	None	0.1306	0.1295	15.61	N	None	-0.37	0.026339	-0.214	0.284	-0.6681	0.146202403952	None	0.99987	0.593	0.591671430083	0.093	0.340908974409	-3.04	0.265	0.649	0.033	None	None	6.85547E-07	0	0	0	0	None	0	0	6.85547E-07	9.00992E-07	0	0	None	N	None
6283	85	S/N	rs1283369258	0.3526	gnomAD-4.0.0	171	None	0.0914	0.0972	14.25	N	-0.599	-0.33	0.017202	-0.363	0.2351	-0.7899	0.0783650798132	None	0.999858	0.566	0.144782658237	None	0.348818004131	-1.34	0.153	0.221	0.153	None	None	2.05664E-06	0	0	0	0	None	0	0	2.05664E-06	2.70297E-06	0	0	None	N	None
6283	85	S/R	None	0.3526	gnomAD-4.0.0	171	None	0.3053	0.298	14.19	N	None	-0.31	0.061639	-0.349	0.2725	-0.7013	0.114398664819	None	1.0	0.641	0.230578612272	0.029	0.35358440876	-2.48	0.321	0.541	0.19	None	None	1.37078E-06	0	0	0	0	None	0	0	1.37078E-06	1.80165E-06	0	0	None	N	None
6284	86	T/A	None	0.1123	gnomAD-4.0.0	172	None	0.0595	0.0596	8.228	N	None	0.03	0.040253	-1.113	0.068	-1.0001	0.0821195563771	None	0.991845	0.426	0.0138822411134	None	0.278275370598	0.45	0.194	0.17	1.0	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
6284	86	T/I	None	0.1123	gnomAD-4.0.0	172	None	0.3199	0.3249	22.3	N	None	-0.14	0.07976	-0.158	0.2053	-0.7529	0.155473890706	None	1.0	0.498	0.303781844768	0.317	0.316847711802	-1.38	0.257	0.789	0.078	None	None	1.59887E-06	0	0	0	2.77731E-05	None	0	0	1.59887E-06	0	0	0	None	N	None
6285	87	R/I	None	0.6546	gnomAD-4.0.0	173	None	0.1246	0.1307	13.15	N	None	-0.27	0.030939	0.257	0.2157	-0.8237	0.208122492365	None	1.0	0.559	0.501624679856	0.171	0.348063439131	-4.11	0.15	0.591	0.029	None	None	6.85758E-07	0	0	0	0	None	0	0	6.85758E-07	9.01164E-07	0	0	None	N	None
6285	87	R/S	None	0.6546	gnomAD-4.0.0	173	None	0.1985	0.1963	14.62	N	None	-0.12	0.040353	-0.505	0.1358	-1.011	0.108086438741	None	0.956913	0.509	0.104622674875	0.012	0.327508330345	-3.07	0.147	0.496	0.195	None	None	1.59963E-06	0	0	0	0	None	0	0	1.59963E-06	0	1.44163E-05	0	None	N	None
6285	87	R/T	rs2079958809	0.6546	gnomAD-3.1.2	173	None	0.0841	0.085	11.57	N	None	-0.15	0.016638	-0.253	0.1038	-0.9997	0.125469718812	None	1.0	0.59	0.360565625551	None	0.346253216267	-2.87	0.179	0.331	0.275	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
6285	87	R/T	rs2079958809	0.6546	gnomAD-4.0.0	173	None	0.0841	0.085	11.57	N	None	-0.15	0.016638	-0.253	0.1038	-0.9997	0.125469718812	None	1.0	0.59	0.360565625551	None	0.346253216267	-2.87	0.179	0.331	0.275	None	None	7.4516E-06	0	0	0	0	None	0	0	7.4516E-06	1.01893E-05	0	0	None	N	None
6286	88	V/A	rs372581135	0.1267	gnomAD-2.1.1	174	None	0.4938	0.4333	None	N	-2.09	None	None	-2.306	None	None	None	None	None	None	None	0.78	None	None	0.29	0.71	None	None	None	4.14E-06	6.5E-05	0	0	0	None	0	None	4.14E-06	0	0	0	None	N	None
6286	88	V/A	rs372581135	0.1267	gnomAD-4.0.0	174	None	0.4938	0.4333	None	N	-2.09	None	None	-2.306	None	None	None	None	None	None	None	0.78	None	None	0.29	0.71	None	None	None	3.24726E-06	1.16577E-04	0	0	0	None	0	0	3.24726E-06	0	0	0	None	N	None
6286	88	V/I	rs149131555	0.1267	gnomAD-2.1.1	174	None	0.081	0.0823	None	N	-0.15	None	None	-0.774	None	None	None	None	None	None	None	0.64	None	None	0.124	0.555	None	None	None	5.87146E-04	6.29191E-03	2.2757E-04	0	0	None	0	None	5.87146E-04	0	7.89E-06	2.83768E-04	None	N	None
6286	88	V/I	rs149131555	0.1267	gnomAD-3.1.2	174	None	0.081	0.0823	None	N	-0.15	None	None	-0.774	None	None	None	None	None	None	None	0.64	None	None	0.124	0.555	None	None	None	1.77464E-03	6.22497E-03	4.58295E-04	0	0	None	0	0	1.77464E-03	2.94E-05	2.07039E-04	9.57854E-04	None	N	None
6286	88	V/I	rs149131555	0.1267	1000 genomes	174	None	0.081	0.0823	None	N	-0.15	None	None	-0.774	None	None	None	None	None	None	None	0.64	None	None	0.124	0.555	None	None	None	3.39457E-03	1.29E-02	0	None	0	0	None	None	3.39457E-03	None	0	None	None	N	None
6286	88	V/I	rs149131555	0.1267	gnomAD-4.0.0	174	None	0.081	0.0823	None	N	-0.15	None	None	-0.774	None	None	None	None	None	None	None	0.64	None	None	0.124	0.555	None	None	None	3.30432E-04	6.29636E-03	3.00802E-04	0	0	None	0	0	3.30432E-04	1.52886E-05	1.10395E-05	3.69098E-04	None	N	None
6287	89	A/T	None	0.1840	gnomAD-4.0.0	175	None	0.0643	0.0651	19.13	N	None	1.18	0.008759	-1.224	0.0276	-1.047	0.0819550916224	None	0.999944	0.312	0.0551355673512	None	0.302090913057	-1.35	0.082	0.107	0.756	None	None	1.64281E-06	0	0	0	0	None	0	0	1.64281E-06	2.95342E-06	0	0	None	N	None
6288	90	L/Q	rs1381105393	0.3131	gnomAD-2.1.1	177	None	0.2867	0.2659	25.3	N	-0.313	0.95	0.043191	-1.098	0.3054	-0.3572	0.467212021082	None	1.0	0.659	0.679835815318	1.0	0.490172237158	-3.5	0.458	0.71	0.02	None	None	4.25E-06	0	0	0	0	None	0	None	4.25E-06	0	9.26E-06	0	None	I	None
6288	90	L/Q	rs1381105393	0.3131	gnomAD-4.0.0	177	None	0.2867	0.2659	25.3	N	-0.313	0.95	0.043191	-1.098	0.3054	-0.3572	0.467212021082	None	1.0	0.659	0.679835815318	1.0	0.490172237158	-3.5	0.458	0.71	0.02	None	None	3.30111E-06	0	0	0	0	None	0	0	3.30111E-06	5.92582E-06	0	0	None	I	None
6288	90	L/V	rs745682900	0.3131	gnomAD-2.1.1	177	None	0.1021	0.1002	21.7	N	-0.241	2.21	0.014473	-1.088	0.0332	-1.0921	0.28309767142	None	1.0	0.474	0.17948927462	0.962	0.434492111206	-1.4	0.146	0.565	1.0	None	None	4.21E-06	0	0	0	0	None	3.59E-05	None	4.21E-06	0	0	0	None	I	None
6288	90	L/V	rs745682900	0.3131	gnomAD-4.0.0	177	None	0.1021	0.1002	21.7	N	-0.241	2.21	0.014473	-1.088	0.0332	-1.0921	0.28309767142	None	1.0	0.474	0.17948927462	0.962	0.434492111206	-1.4	0.146	0.565	1.0	None	None	1.64361E-06	0	0	0	0	None	0	0	1.64361E-06	0	1.48965E-05	0	None	I	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

Select a Data Table to View:

Custom Data Table

Map SAVs to Structure

Select a Data Table to View:

Select columns to include

Custom Data Table

Map SAVs to Structure