TITINdb

Map SAVs to Structure

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
21177	1	D/E	1	rs879247635	0.4796	None	gnomAD-3.1.2	6.58E-06
21177	1	D/E	1	rs879247635	0.4796	None	gnomAD-4.0.0	6.57661E-06
21178	2	A/G	2	None	0.4687	None	gnomAD-4.0.0	4.84588E-06
21178	2	A/S	2	rs1299782984	0.4687	None	gnomAD-2.1.1	4.16E-06
21179	3	S/G	3	rs772529311	0.4327	None	gnomAD-2.1.1	1.24E-05
21179	3	S/G	3	rs772529311	0.4327	None	gnomAD-3.1.2	6.58E-06
21179	3	S/G	3	rs772529311	0.4327	None	gnomAD-4.0.0	6.85293E-06
21180	4	M/K	4	rs774558749	0.1544	None	gnomAD-4.0.0	3.2228E-06
21180	4	M/L	4	rs2049352693	0.1544	None	gnomAD-4.0.0	7.56728E-06
21180	4	M/T	4	rs774558749	0.1544	None	gnomAD-2.1.1	4.12E-06
21182	6	K/E	9	rs565176987	0.8617	None	gnomAD-2.1.1	7.27E-06
21182	6	K/E	9	rs565176987	0.8617	None	gnomAD-3.1.2	1.97E-05
21182	6	K/E	9	rs565176987	0.8617	None	1000 genomes	1.99681E-04
21182	6	K/E	9	rs565176987	0.8617	None	gnomAD-4.0.0	6.46277E-06
21184	8	V/A	13	rs747755332	0.2561	None	gnomAD-2.1.1	4.08E-06
21184	8	V/A	13	rs747755332	0.2561	None	gnomAD-4.0.0	6.86302E-07
21184	8	V/D	13	None	0.2561	None	gnomAD-4.0.0	6.86302E-07
21184	8	V/I	13	rs1290013861	0.2561	None	gnomAD-3.1.2	1.32E-05
21184	8	V/I	13	rs1290013861	0.2561	None	gnomAD-4.0.0	3.10797E-06
21185	9	I/T	14	rs794729473	0.5138	None	gnomAD-4.0.0	2.40065E-06
21185	9	I/V	14	rs1329536424	0.5138	None	gnomAD-3.1.2	6.58E-06
21185	9	I/V	14	rs1329536424	0.5138	None	gnomAD-4.0.0	6.57601E-06
21186	10	V/M	16	None	0.1888	None	gnomAD-4.0.0	6.85778E-07
21187	11	R/G	18	rs368288863	0.7884	None	gnomAD-2.1.1	4.05E-06
21187	11	R/G	18	rs368288863	0.7884	None	gnomAD-3.1.2	1.32E-05
21187	11	R/G	18	rs368288863	0.7884	None	gnomAD-4.0.0	2.48153E-06
21187	11	R/K	18	None	0.7884	None	gnomAD-4.0.0	2.73989E-06
21188	12	A/G	23	rs746456662	0.3716	None	gnomAD-2.1.1	4.05E-06
21188	12	A/G	23	rs746456662	0.3716	None	gnomAD-4.0.0	1.59493E-06
21188	12	A/P	23	None	0.3716	None	gnomAD-4.0.0	1.36986E-06
21188	12	A/T	23	None	0.3716	None	gnomAD-4.0.0	6.84928E-07
21189	13	G/V	24	None	0.3704	None	gnomAD-4.0.0	1.36963E-06
21190	14	C/G	25	rs779738957	0.2997	None	gnomAD-2.1.1	8.09E-06
21190	14	C/G	25	rs779738957	0.2997	None	gnomAD-4.0.0	3.18873E-06
21191	15	P/A	26	None	0.3942	None	gnomAD-4.0.0	3.42362E-06
21191	15	P/R	26	rs1425522000	0.3942	None	gnomAD-2.1.1	4.04E-06
21191	15	P/R	26	rs1425522000	0.3942	None	gnomAD-4.0.0	1.594E-06
21192	16	I/V	28	rs758357424	0.1282	None	gnomAD-2.1.1	4.04E-06
21192	16	I/V	28	rs758357424	0.1282	None	gnomAD-3.1.2	1.97E-05
21192	16	I/V	28	rs758357424	0.1282	None	gnomAD-4.0.0	1.97371E-05
21193	17	R/C	29	rs376800688	0.6527	None	gnomAD-2.1.1	2.86899E-04
21193	17	R/C	29	rs376800688	0.6527	None	gnomAD-3.1.2	3.35597E-04
21193	17	R/C	29	rs376800688	0.6527	None	gnomAD-4.0.0	4.51428E-04
21193	17	R/H	29	rs372267046	0.6527	None	gnomAD-2.1.1	7.89E-05
21193	17	R/H	29	rs372267046	0.6527	None	gnomAD-3.1.2	7.24E-05
21193	17	R/H	29	rs372267046	0.6527	None	gnomAD-4.0.0	9.1164E-05
21194	18	L/P	30	rs367838375	0.1258	None	gnomAD-2.1.1	4.66E-05
21194	18	L/P	30	rs367838375	0.1258	None	gnomAD-3.1.2	5.92E-05
21194	18	L/P	30	rs367838375	0.1258	None	gnomAD-4.0.0	1.61219E-05
21194	18	L/V	30	None	0.1258	None	gnomAD-4.0.0	1.20032E-06
21196	20	A/G	33	rs1460483373	0.2449	None	gnomAD-4.0.0	1.59346E-06
21197	21	I/T	34	rs1473107263	0.6315	None	gnomAD-3.1.2	6.58E-06
21197	21	I/T	34	rs1473107263	0.6315	None	gnomAD-4.0.0	7.69578E-06
21197	21	I/V	34	rs72646855	0.6315	None	gnomAD-2.1.1	6.05522E-04
21197	21	I/V	34	rs72646855	0.6315	None	gnomAD-3.1.2	5.45866E-04
21197	21	I/V	34	rs72646855	0.6315	None	gnomAD-4.0.0	7.41523E-04
21198	22	V/A	35	None	0.1945	None	gnomAD-4.0.0	1.59332E-06
21198	22	V/G	35	rs1559553614	0.1945	None	gnomAD-2.1.1	4.04E-06
21198	22	V/G	35	rs1559553614	0.1945	None	gnomAD-4.0.0	1.59332E-06
21198	22	V/L	35	None	0.1945	None	gnomAD-4.0.0	6.84584E-07
21198	22	V/M	35	None	0.1945	None	gnomAD-4.0.0	6.84584E-07
21200	24	G/E	40	rs1313160165	0.3438	None	gnomAD-2.1.1	4.04E-06
21200	24	G/E	40	rs1313160165	0.3438	None	gnomAD-4.0.0	6.37284E-06
21200	24	G/R	40	None	0.3438	None	gnomAD-4.0.0	3.1865E-06
21201	25	R/L	41	None	0.7225	None	gnomAD-4.0.0	6.84595E-07
21201	25	R/Q	41	rs763273464	0.7225	None	gnomAD-2.1.1	2.42E-05
21201	25	R/Q	41	rs763273464	0.7225	None	gnomAD-3.1.2	6.58E-06
21201	25	R/Q	41	rs763273464	0.7225	None	gnomAD-4.0.0	1.17811E-05
21202	26	P/S	42	rs752725604	0.5243	None	gnomAD-2.1.1	4.04E-06
21202	26	P/S	42	rs752725604	0.5243	None	gnomAD-4.0.0	2.73823E-06
21202	26	P/T	42	None	0.5243	None	gnomAD-4.0.0	6.84558E-07
21203	27	A/D	43	rs544707116	0.5791	None	gnomAD-2.1.1	8.07E-06
21203	27	A/D	43	rs544707116	0.5791	None	gnomAD-3.1.2	1.97E-05
21203	27	A/D	43	rs544707116	0.5791	None	1000 genomes	5.99042E-04
21203	27	A/D	43	rs544707116	0.5791	None	gnomAD-4.0.0	1.31527E-05
21205	29	K/E	45	rs794727409	0.7107	None	gnomAD-2.1.1	7.16E-06
21205	29	K/E	45	rs794727409	0.7107	None	gnomAD-3.1.2	1.97E-05
21205	29	K/E	45	rs794727409	0.7107	None	gnomAD-4.0.0	6.20028E-06
21205	29	K/I	45	rs886042512	0.7107	None	gnomAD-2.1.1	1.21E-05
21205	29	K/I	45	rs886042512	0.7107	None	gnomAD-4.0.0	4.7792E-06
21205	29	K/N	45	rs771189924	0.7107	None	gnomAD-2.1.1	4.03E-06
21205	29	K/N	45	rs771189924	0.7107	None	gnomAD-4.0.0	1.59312E-06
21206	30	V/A	46	rs370145029	0.2728	None	gnomAD-2.1.1	2.15E-05
21206	30	V/A	46	rs370145029	0.2728	None	gnomAD-3.1.2	5.27E-05
21206	30	V/A	46	rs370145029	0.2728	None	1000 genomes	1.99681E-04
21206	30	V/A	46	rs370145029	0.2728	None	gnomAD-4.0.0	8.68012E-06
21206	30	V/D	46	None	0.2728	None	gnomAD-4.0.0	6.84545E-07
21206	30	V/I	46	None	0.2728	None	gnomAD-4.0.0	1.20032E-06
21207	31	T/P	47	None	0.3912	None	gnomAD-4.0.0	1.59309E-06
21209	33	R/Q	49	rs148684589	0.4349	None	gnomAD-2.1.1	1.00297E-04
21209	33	R/Q	49	rs148684589	0.4349	None	gnomAD-3.1.2	1.51344E-04
21209	33	R/Q	49	rs148684589	0.4349	None	1000 genomes	1.99681E-04
21209	33	R/Q	49	rs148684589	0.4349	None	gnomAD-4.0.0	7.37808E-05
21211	35	V/A	51	rs397517654	0.4848	None	gnomAD-4.0.0	2.05364E-06
21211	35	V/I	51	None	0.4848	None	gnomAD-4.0.0	1.20032E-06
21212	36	G/S	52	rs1381842230	0.6565	None	gnomAD-4.0.0	1.3691E-06
21213	37	I/M	55	None	0.5667	None	gnomAD-4.0.0	1.20032E-06
21213	37	I/T	55	None	0.5667	None	gnomAD-4.0.0	1.59312E-06
21213	37	I/V	55	rs2049329163	0.5667	None	gnomAD-3.1.2	6.58E-06
21213	37	I/V	55	rs2049329163	0.5667	None	gnomAD-4.0.0	6.57834E-06
21214	38	D/A	56	rs779686062	1.1355	None	gnomAD-2.1.1	1.21E-05
21214	38	D/A	56	rs779686062	1.1355	None	gnomAD-4.0.0	1.2322E-05
21214	38	D/G	56	None	1.1355	None	gnomAD-4.0.0	6.84554E-07
21214	38	D/N	56	rs746677565	1.1355	None	gnomAD-2.1.1	4.03E-06
21216	40	V/M	59	rs542681131	0.8389	None	gnomAD-2.1.1	2.82E-05
21216	40	V/M	59	rs542681131	0.8389	None	gnomAD-3.1.2	3.29E-05
21216	40	V/M	59	rs542681131	0.8389	None	1000 genomes	1.99681E-04
21216	40	V/M	59	rs542681131	0.8389	None	gnomAD-4.0.0	1.98398E-05
21217	41	V/A	69	rs1351844757	0.2193	None	gnomAD-2.1.1	3.19E-05
21217	41	V/A	69	rs1351844757	0.2193	None	gnomAD-3.1.2	1.32E-05
21217	41	V/A	69	rs1351844757	0.2193	None	gnomAD-4.0.0	3.84796E-06
21217	41	V/I	69	rs1214985099	0.2193	None	gnomAD-2.1.1	4.03E-06
21217	41	V/I	69	rs1214985099	0.2193	None	gnomAD-4.0.0	1.5932E-06
21218	42	R/G	70	rs778966200	0.8492	None	gnomAD-2.1.1	4.03E-06
21218	42	R/G	70	rs778966200	0.8492	None	gnomAD-4.0.0	2.05372E-06
21220	44	G/E	102	rs757154541	0.1842	None	gnomAD-2.1.1	4.04E-06
21221	45	Q/H	122	None	0.6113	None	gnomAD-4.0.0	1.59339E-06
21221	45	Q/K	122	rs2049322891	0.6113	None	gnomAD-4.0.0	1.5935E-06
21222	46	V/A	123	rs183595734	0.3172	None	gnomAD-2.1.1	1.07E-05
21222	46	V/A	123	rs183595734	0.3172	None	gnomAD-3.1.2	1.97E-05
21222	46	V/A	123	rs183595734	0.3172	None	1000 genomes	1.99681E-04
21222	46	V/A	123	rs183595734	0.3172	None	gnomAD-4.0.0	7.44027E-06
21222	46	V/G	123	rs183595734	0.3172	None	gnomAD-3.1.2	6.58E-06
21222	46	V/G	123	rs183595734	0.3172	None	gnomAD-4.0.0	2.48027E-06
21223	47	D/G	125	None	0.4684	None	gnomAD-4.0.0	1.20032E-06
21223	47	D/H	125	rs753562502	0.4684	None	gnomAD-2.1.1	7.17E-06
21223	47	D/H	125	rs753562502	0.4684	None	gnomAD-3.1.2	6.58E-06
21223	47	D/H	125	rs753562502	0.4684	None	gnomAD-4.0.0	2.48044E-06
21223	47	D/N	125	None	0.4684	None	gnomAD-4.0.0	2.05389E-06
21225	49	V/A	130	rs1396646735	0.4984	None	gnomAD-2.1.1	4.04E-06
21225	49	V/A	130	rs1396646735	0.4984	None	gnomAD-4.0.0	4.10775E-06
21225	49	V/I	130	rs777568221	0.4984	None	gnomAD-2.1.1	8.07E-06
21225	49	V/I	130	rs777568221	0.4984	None	gnomAD-4.0.0	3.18719E-06
21226	50	D/G	131	rs879061715	0.8630	None	gnomAD-4.0.0	2.40064E-06
21227	51	T/A	134	rs752958666	0.5507	None	gnomAD-2.1.1	4.04E-06
21227	51	T/A	134	rs752958666	0.5507	None	gnomAD-3.1.2	1.32E-05
21227	51	T/A	134	rs752958666	0.5507	None	gnomAD-4.0.0	4.34069E-06
21227	51	T/P	134	None	0.5507	None	gnomAD-4.0.0	6.84621E-07
21227	51	T/S	134	rs752958666	0.5507	None	gnomAD-3.1.2	6.58E-06
21227	51	T/S	134	rs752958666	0.5507	None	gnomAD-4.0.0	6.57964E-06
21228	52	M/K	135	None	0.2491	None	gnomAD-4.0.0	6.84639E-07
21228	52	M/T	135	rs1397983700	0.2491	None	gnomAD-2.1.1	4.04E-06
21228	52	M/T	135	rs1397983700	0.2491	None	gnomAD-4.0.0	6.84639E-07
21228	52	M/V	135	None	0.2491	None	gnomAD-4.0.0	1.36927E-06
21229	53	A/V	136	rs1209410552	0.0891	None	gnomAD-3.1.2	6.58E-06
21229	53	A/V	136	rs1209410552	0.0891	None	gnomAD-4.0.0	1.02638E-05
21232	56	V/I	139	rs767582181	0.2582	None	gnomAD-2.1.1	4.04E-06
21232	56	V/I	139	rs767582181	0.2582	None	gnomAD-4.0.0	6.84705E-07
21232	56	V/L	139	None	0.2582	None	gnomAD-4.0.0	6.84705E-07
21233	57	I/M	140	None	0.1081	None	gnomAD-4.0.0	6.84706E-07
21233	57	I/T	140	None	0.1081	None	gnomAD-4.0.0	6.84678E-07
21234	58	P/L	141	None	0.4596	None	gnomAD-4.0.0	1.59405E-06
21234	58	P/S	141	rs1335943731	0.4596	None	gnomAD-2.1.1	3.19E-05
21234	58	P/S	141	rs1335943731	0.4596	None	gnomAD-3.1.2	6.58E-06
21234	58	P/S	141	rs1335943731	0.4596	None	gnomAD-4.0.0	3.04544E-06
21235	59	N/D	143	rs786205305	0.7306	None	gnomAD-2.1.1	4.04E-06
21235	59	N/D	143	rs786205305	0.7306	None	gnomAD-4.0.0	1.59381E-06
21235	59	N/S	143	rs751607765	0.7306	None	gnomAD-2.1.1	2.15E-05
21235	59	N/S	143	rs751607765	0.7306	None	gnomAD-3.1.2	3.95E-05
21235	59	N/S	143	rs751607765	0.7306	None	gnomAD-4.0.0	2.10844E-05
21237	61	T/A	145	rs766847414	0.3516	None	gnomAD-2.1.1	3.19E-05
21237	61	T/A	145	rs766847414	0.3516	None	gnomAD-3.1.2	1.32E-05
21237	61	T/A	145	rs766847414	0.3516	None	gnomAD-4.0.0	4.34125E-06
21237	61	T/I	145	None	0.3516	None	gnomAD-4.0.0	1.20033E-06
21238	62	R/C	146	rs190432620	0.7666	None	gnomAD-2.1.1	2.02E-05
21238	62	R/C	146	rs190432620	0.7666	None	gnomAD-3.1.2	2.63E-05
21238	62	R/C	146	rs190432620	0.7666	None	1000 genomes	1.99681E-04
21238	62	R/C	146	rs190432620	0.7666	None	gnomAD-4.0.0	1.11632E-05
21238	62	R/H	146	rs544396866	0.7666	None	gnomAD-2.1.1	1.79E-05
21238	62	R/H	146	rs544396866	0.7666	None	gnomAD-3.1.2	2.63E-05
21238	62	R/H	146	rs544396866	0.7666	None	1000 genomes	1.99681E-04
21238	62	R/H	146	rs544396866	0.7666	None	gnomAD-4.0.0	1.17827E-05
21238	62	R/L	146	rs544396866	0.7666	None	gnomAD-2.1.1	4.04E-06
21238	62	R/L	146	rs544396866	0.7666	None	gnomAD-4.0.0	6.84728E-07
21239	63	D/E	148	None	0.6095	None	gnomAD-4.0.0	1.59406E-06
21240	64	D/N	149	rs1031557327	0.1788	None	gnomAD-3.1.2	6.58E-06
21240	64	D/N	149	rs1031557327	0.1788	None	gnomAD-4.0.0	2.56637E-06
21246	70	L/F	156	rs2049306666	0.1238	None	gnomAD-3.1.2	6.58E-06
21246	70	L/F	156	rs2049306666	0.1238	None	gnomAD-4.0.0	6.57903E-06
21246	70	L/V	156	None	0.1238	None	gnomAD-4.0.0	1.59435E-06
21247	71	T/A	157	None	0.1565	None	gnomAD-4.0.0	1.59453E-06
21248	72	L/F	158	rs771468174	0.2017	None	gnomAD-2.1.1	4.05E-06
21248	72	L/F	158	rs771468174	0.2017	None	gnomAD-4.0.0	6.16354E-06
21248	72	L/P	158	rs745323281	0.2017	None	gnomAD-2.1.1	3.24E-05
21248	72	L/P	158	rs745323281	0.2017	None	gnomAD-3.1.2	1.32E-05
21248	72	L/P	158	rs745323281	0.2017	None	gnomAD-4.0.0	2.10913E-05
21249	73	V/L	159	None	0.3494	None	gnomAD-4.0.0	1.36984E-06
21249	73	V/M	159	None	0.3494	None	gnomAD-4.0.0	3.4246E-06
21250	74	N/K	161	rs773738001	0.1875	None	gnomAD-2.1.1	8.11E-06
21250	74	N/K	161	rs773738001	0.1875	None	gnomAD-4.0.0	3.19096E-06
21251	75	P/A	162	None	0.6938	None	gnomAD-4.0.0	6.85253E-07
21251	75	P/S	162	None	0.6938	None	gnomAD-4.0.0	4.11152E-06
21251	75	P/T	162	None	0.6938	None	gnomAD-4.0.0	6.85253E-07
21252	76	A/P	163	rs1414305945	0.6679	None	gnomAD-2.1.1	3.19E-05
21252	76	A/P	163	rs1414305945	0.6679	None	gnomAD-3.1.2	6.58E-06
21252	76	A/P	163	rs1414305945	0.6679	None	gnomAD-4.0.0	6.58085E-06
21253	77	G/V	164	rs770861395	0.3582	None	gnomAD-2.1.1	3.19E-05
21253	77	G/V	164	rs770861395	0.3582	None	gnomAD-3.1.2	6.58E-06
21253	77	G/V	164	rs770861395	0.3582	None	gnomAD-4.0.0	6.58033E-06
21254	78	E/K	165	None	0.5947	None	gnomAD-4.0.0	1.20034E-06
21256	80	A/T	168	rs1277491841	0.3047	None	gnomAD-2.1.1	4.08E-06
21256	80	A/T	168	rs1277491841	0.3047	None	gnomAD-4.0.0	1.6E-06
21259	83	V/I	172	rs371286595	0.1950	None	gnomAD-2.1.1	8.34E-05
21259	83	V/I	172	rs371286595	0.1950	None	gnomAD-3.1.2	1.11866E-04
21259	83	V/I	172	rs371286595	0.1950	None	gnomAD-4.0.0	3.17018E-05
21261	85	V/I	174	None	0.1277	None	gnomAD-4.0.0	3.20566E-06
21262	86	R/G	175	None	0.6088	None	gnomAD-4.0.0	1.60277E-06
21262	86	R/T	175	rs1342165359	0.6088	None	gnomAD-2.1.1	4.09E-06
21262	86	R/T	175	rs1342165359	0.6088	None	gnomAD-4.0.0	1.60321E-06
21263	87	V/G	177	None	0.1465	None	gnomAD-4.0.0	1.60281E-06
21263	87	V/I	177	rs1298535121	0.1465	None	gnomAD-2.1.1	4.09E-06
21263	87	V/I	177	rs1298535121	0.1465	None	gnomAD-4.0.0	3.20539E-06

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
21177	1	D/E	rs879247635	0.4796	gnomAD-3.1.2	1	None	0.8259	0.8117	25.1	N	None	0.25	0.023993	-0.203	0.4267	-0.1482	0.379369986977	2.615	0.999473	0.375	0.402326594622	0.993	0.708623766899	-3.2	0.324	0.503	0.017	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
21177	1	D/E	rs879247635	0.4796	gnomAD-4.0.0	1	None	0.8259	0.8117	25.1	N	None	0.25	0.023993	-0.203	0.4267	-0.1482	0.379369986977	2.615	0.999473	0.375	0.402326594622	0.993	0.708623766899	-3.2	0.324	0.503	0.017	None	None	6.57661E-06	2.41243E-05	0	0	0	None	0	0	6.57661E-06	0	0	0	None	N	None
21178	2	A/G	None	0.4687	gnomAD-4.0.0	2	None	0.2737	0.2528	27.5	N	None	0.08	0.018713	-0.196	0.2996	-0.603	0.0901395718251	1.985	0.999999	0.429	0.550545596621	0.025	0.573597192764	-3.1	0.306	0.309	0.049	None	None	4.84588E-06	0	0	0	0	None	0	0	4.84588E-06	5.807E-06	0	3.06185E-05	None	N	None
21178	2	A/S	rs1299782984	0.4687	gnomAD-2.1.1	2	None	0.1473	0.1376	24.1	N	-0.668	0.18	0.024143	-0.393	0.2373	-0.5958	0.221449194582	1.525	0.999998	0.362	0.508637063495	0.805	0.560318589211	-2.3	0.194	0.43	0.085	None	None	4.16E-06	0	0	0	5.65E-05	None	0	None	4.16E-06	0	0	0	None	N	None
21179	3	S/G	rs772529311	0.4327	gnomAD-2.1.1	3	None	0.1095	0.1151	23.8	N	0.108	0.12	0.018868	-0.387	0.2317	-0.7315	0.0822587675246	1.485	0.999183	0.426	0.28798054836	0.011	0.615314483643	-2.87	0.213	0.239	0.102	None	None	1.24E-05	0	0	0	5.64E-05	None	0	None	1.24E-05	0	1.82E-05	0	None	I	None
21179	3	S/G	rs772529311	0.4327	gnomAD-3.1.2	3	None	0.1095	0.1151	23.8	N	0.108	0.12	0.018868	-0.387	0.2317	-0.7315	0.0822587675246	1.485	0.999183	0.426	0.28798054836	0.011	0.615314483643	-2.87	0.213	0.239	0.102	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
21179	3	S/G	rs772529311	0.4327	gnomAD-4.0.0	3	None	0.1095	0.1151	23.8	N	0.108	0.12	0.018868	-0.387	0.2317	-0.7315	0.0822587675246	1.485	0.999183	0.426	0.28798054836	0.011	0.615314483643	-2.87	0.213	0.239	0.102	None	None	6.85293E-06	0	0	0	6.73129E-05	None	0	0	6.85293E-06	5.95919E-06	0	1.61119E-05	None	I	None
21180	4	M/K	rs774558749	0.1544	gnomAD-4.0.0	4	None	0.8409	0.8542	25.6	D	-0.089	0.25	0.052657	-0.655	0.2205	-0.6893	0.17529077387	2.24	0.998573	0.553	0.640709723699	0.491	0.633568584919	-4.27	0.35	0.388	0.003	None	None	3.2228E-06	0	0	0	0	None	0	0	3.2228E-06	2.89764E-06	1.4529E-05	0	None	N	None
21180	4	M/L	rs2049352693	0.1544	gnomAD-4.0.0	4	None	0.1118	0.1316	24.1	N	None	0.48	0.012549	-0.902	0.063	-0.9691	0.0783274476065	-0.71	0.82732	0.517	0.401753679984	None	0.550964951515	-1.47	0.184	0.153	0.791	None	None	7.56728E-06	0	0	0	0	None	0	0	7.56728E-06	0	1.28996E-04	0	None	N	None
21180	4	M/T	rs774558749	0.1544	gnomAD-2.1.1	4	None	0.6923	0.7196	24.7	N	-0.333	0.29	0.039444	-1.082	0.1696	-0.8874	0.097582146551	1.435	0.989731	0.412	0.741590790702	0.001	0.666126728058	-4.07	0.28	0.261	0.005	None	None	4.12E-06	0	0	0	0	None	0	None	4.12E-06	0	9.1E-06	0	None	N	None
21182	6	K/E	rs565176987	0.8617	gnomAD-2.1.1	9	None	0.5737	0.5053	26.9	D	0.249	0.15	0.018492	0.11	0.2188	-0.7827	0.138332810546	1.385	0.999982	0.613	0.266385636622	0.067	0.631089687347	-2.87	0.22	0.346	0.008	None	None	7.27E-06	0	0	0	1.03821E-04	None	0	None	7.27E-06	0	0	0	None	I	None
21182	6	K/E	rs565176987	0.8617	gnomAD-3.1.2	9	None	0.5737	0.5053	26.9	D	0.249	0.15	0.018492	0.11	0.2188	-0.7827	0.138332810546	1.385	0.999982	0.613	0.266385636622	0.067	0.631089687347	-2.87	0.22	0.346	0.008	None	None	1.97E-05	0	0	0	5.81621E-04	None	0	0	1.97E-05	0	0	0	None	I	None
21182	6	K/E	rs565176987	0.8617	1000 genomes	9	None	0.5737	0.5053	26.9	D	0.249	0.15	0.018492	0.11	0.2188	-0.7827	0.138332810546	1.385	0.999982	0.613	0.266385636622	0.067	0.631089687347	-2.87	0.22	0.346	0.008	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	I	None
21182	6	K/E	rs565176987	0.8617	gnomAD-4.0.0	9	None	0.5737	0.5053	26.9	D	0.249	0.15	0.018492	0.11	0.2188	-0.7827	0.138332810546	1.385	0.999982	0.613	0.266385636622	0.067	0.631089687347	-2.87	0.22	0.346	0.008	None	None	6.46277E-06	0	0	0	1.22124E-04	None	0	0	6.46277E-06	0	0	0	None	I	None
21184	8	V/A	rs747755332	0.2561	gnomAD-2.1.1	13	None	0.5374	0.5344	32.0	N	-1.579	-0.47	0.029793	-1.642	0.456	-0.0175	0.342323193892	1.845	0.999963	0.585	0.668205050051	0.954	0.608947753906	-2.8	0.528	0.496	0.032	None	None	4.08E-06	0	2.93E-05	0	0	None	0	None	4.08E-06	0	0	0	None	I	None
21184	8	V/A	rs747755332	0.2561	gnomAD-4.0.0	13	None	0.5374	0.5344	32.0	N	-1.579	-0.47	0.029793	-1.642	0.456	-0.0175	0.342323193892	1.845	0.999963	0.585	0.668205050051	0.954	0.608947753906	-2.8	0.528	0.496	0.032	None	None	6.86302E-07	0	2.24992E-05	0	0	None	0	0	6.86302E-07	0	0	0	None	I	None
21184	8	V/D	None	0.2561	gnomAD-4.0.0	13	None	0.9029	0.8925	34.0	D	None	-0.59	0.05527	-1.436	0.6112	0.4056	0.561645299174	2.945	1.0	0.712	0.907794322601	0.998	0.61191868782	-5.13	0.737	0.687	0.002	None	None	6.86302E-07	0	0	0	0	None	0	0	6.86302E-07	9.01756E-07	0	0	None	I	None
21184	8	V/I	rs1290013861	0.2561	gnomAD-3.1.2	13	None	0.0987	0.1021	23.6	N	None	-0.43	0.044122	-0.596	0.2517	-0.5729	0.21770708725	None	0.9996	0.469	0.471941563831	0.835	0.462803781033	-0.37	0.217	0.457	0.342	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	I	None
21184	8	V/I	rs1290013861	0.2561	gnomAD-4.0.0	13	None	0.0987	0.1021	23.6	N	None	-0.43	0.044122	-0.596	0.2517	-0.5729	0.21770708725	None	0.9996	0.469	0.471941563831	0.835	0.462803781033	-0.37	0.217	0.457	0.342	None	None	3.10797E-06	0	0	0	0	None	0	0	3.10797E-06	4.24897E-06	0	0	None	I	None
21185	9	I/T	rs794729473	0.5138	gnomAD-4.0.0	14	None	0.0585	0.0619	22.3	N	None	-0.13	0.015745	-1.42	0.0696	-1.0256	0.105715252096	-1.22	1.0	0.439	0.132336055621	None	0.314798951149	0.08	0.126	0.093	1.0	None	None	2.40065E-06	0	0	0	0	None	0	0	2.40065E-06	1.3125E-06	6.07533E-05	0	None	I	None
21185	9	I/V	rs1329536424	0.5138	gnomAD-3.1.2	14	None	0.0652	0.0711	21.7	N	None	-0.08	0.010213	-0.778	0.1076	-0.9742	0.0703051542146	-0.665	1.0	0.409	0.46614307118	None	0.29471257329	0.4	0.11	0.086	0.605	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
21185	9	I/V	rs1329536424	0.5138	gnomAD-4.0.0	14	None	0.0652	0.0711	21.7	N	None	-0.08	0.010213	-0.778	0.1076	-0.9742	0.0703051542146	-0.665	1.0	0.409	0.46614307118	None	0.29471257329	0.4	0.11	0.086	0.605	None	None	6.57601E-06	2.41266E-05	0	0	0	None	0	0	6.57601E-06	0	0	0	None	I	None
21186	10	V/M	None	0.1888	gnomAD-4.0.0	16	None	0.6261	0.6056	24.8	D	None	-0.63	0.06138	-0.69	0.5886	0.4473	0.345699605071	3.545	0.999997	0.729	0.695291002561	0.942	0.699549853802	-2.37	0.604	0.547	0.003	None	None	6.85778E-07	0	0	0	0	None	0	0	6.85778E-07	0	1.16417E-05	0	None	I	None
21187	11	R/G	rs368288863	0.7884	gnomAD-2.1.1	18	None	0.9228	0.9076	None	N	-0.173	None	None	-0.125	None	None	None	None	None	None	None	0.892	None	None	0.467	0.575	None	None	None	4.05E-06	6.47E-05	0	0	0	None	0	None	4.05E-06	0	0	0	None	I	None
21187	11	R/G	rs368288863	0.7884	gnomAD-3.1.2	18	None	0.9228	0.9076	None	N	-0.173	None	None	-0.125	None	None	None	None	None	None	None	0.892	None	None	0.467	0.575	None	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	I	None
21187	11	R/G	rs368288863	0.7884	gnomAD-4.0.0	18	None	0.9228	0.9076	None	N	-0.173	None	None	-0.125	None	None	None	None	None	None	None	0.892	None	None	0.467	0.575	None	None	None	2.48153E-06	0	0	0	0	None	0	0	2.48153E-06	3.39306E-06	0	0	None	I	None
21187	11	R/K	None	0.7884	gnomAD-4.0.0	18	None	0.289	0.2628	24.3	N	None	-0.18	0.028674	-0.025	0.196	-0.6994	0.198471850108	0.52	0.999938	0.519	0.326616659874	0.63	0.74833804369	-2.13	0.213	0.537	0.229	None	None	2.73989E-06	0	0	0	0	None	0	0	2.73989E-06	3.60065E-06	0	0	None	I	None
21188	12	A/G	rs746456662	0.3716	gnomAD-2.1.1	23	None	0.3712	0.3856	26.0	D	-0.248	0.88	0.069137	-0.503	0.2568	-0.4569	0.0937571764374	4.1	1.0	0.512	0.212008924253	0.067	0.652591764927	-3.2	0.371	0.369	0.012	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	0	8.96E-06	0	None	I	None
21188	12	A/G	rs746456662	0.3716	gnomAD-4.0.0	23	None	0.3712	0.3856	26.0	D	-0.248	0.88	0.069137	-0.503	0.2568	-0.4569	0.0937571764374	4.1	1.0	0.512	0.212008924253	0.067	0.652591764927	-3.2	0.371	0.369	0.012	None	None	1.59493E-06	0	0	0	0	None	0	0	1.59493E-06	2.86411E-06	0	0	None	I	None
21188	12	A/P	None	0.3716	gnomAD-4.0.0	23	None	0.9462	0.945	28.1	N	None	0.93	0.019676	-0.415	0.309	-0.4533	0.499990082143	2.82	1.0	0.615	0.273070737957	0.998	0.708771824837	-4.0	0.463	0.735	0.005	None	None	1.36986E-06	0	0	0	0	None	0	0	1.36986E-06	1.80019E-06	0	0	None	I	None
21188	12	A/T	None	0.3716	gnomAD-4.0.0	23	None	0.4392	0.5127	27.5	N	None	0.93	0.027823	-0.639	0.3272	-0.3183	0.392344087065	2.58	1.0	0.481	0.227260227426	0.994	0.667372107506	-3.2	0.401	0.732	0.004	None	None	6.84928E-07	0	0	0	0	None	0	0	6.84928E-07	0	0	1.6587E-05	None	I	None
21189	13	G/V	None	0.3704	gnomAD-4.0.0	24	None	0.9201	0.9057	32.0	D	None	-1.49	0.082457	-0.405	0.7999	0.9083	0.495459876918	4.495	1.0	0.837	0.879814937172	0.999	0.648810446262	-6.83	0.823	0.834	0.002	None	None	1.36963E-06	0	0	0	0	None	0	0	1.36963E-06	1.8E-06	0	0	None	I	None
21190	14	C/G	rs779738957	0.2997	gnomAD-2.1.1	25	None	0.3259	0.2855	28.0	N	-1.006	1.15	0.027181	-1.08	0.1031	-0.762	0.515532960109	0.32	1.0	0.479	0.668689390126	1.0	0.638913869858	-8.67	0.486	0.754	0.404	None	None	8.09E-06	0	2.91E-05	0	0	None	0	None	8.09E-06	0	8.94E-06	0	None	I	None
21190	14	C/G	rs779738957	0.2997	gnomAD-4.0.0	25	None	0.3259	0.2855	28.0	N	-1.006	1.15	0.027181	-1.08	0.1031	-0.762	0.515532960109	0.32	1.0	0.479	0.668689390126	1.0	0.638913869858	-8.67	0.486	0.754	0.404	None	None	3.18873E-06	0	2.29106E-05	0	0	None	0	0	3.18873E-06	2.86293E-06	0	0	None	I	None
21191	15	P/A	None	0.3942	gnomAD-4.0.0	26	None	0.2266	0.2158	28.8	N	None	0.97	0.022655	-1.425	0.2356	-0.7077	0.457628982806	1.91	1.0	0.594	0.324986149311	1.0	0.732587456703	-6.1	0.366	0.706	0.016	None	None	3.42362E-06	0	0	0	0	None	0	0	3.42362E-06	3.5996E-06	0	1.65793E-05	None	I	None
21191	15	P/R	rs1425522000	0.3942	gnomAD-2.1.1	26	None	0.8008	0.7622	32.0	N	0.061	0.98	0.033724	-0.599	0.2591	-0.642	0.4773412541	2.01	1.0	0.625	0.423597194605	1.0	0.782096743584	-6.9	0.455	0.758	0.004	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.94E-06	0	None	I	None
21191	15	P/R	rs1425522000	0.3942	gnomAD-4.0.0	26	None	0.8008	0.7622	32.0	N	0.061	0.98	0.033724	-0.599	0.2591	-0.642	0.4773412541	2.01	1.0	0.625	0.423597194605	1.0	0.782096743584	-6.9	0.455	0.758	0.004	None	None	1.594E-06	0	0	0	0	None	0	0	1.594E-06	2.86244E-06	0	0	None	I	None
21192	16	I/V	rs758357424	0.1282	gnomAD-2.1.1	28	None	0.1499	0.1763	25.1	N	-1.013	1.24	0.015087	-1.61	0.163	-0.8499	0.422359933901	1.19	0.999999	0.471	0.366277470483	0.993	0.503998935223	-0.8	0.24	0.359	0.118	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.93E-06	0	None	I	None
21192	16	I/V	rs758357424	0.1282	gnomAD-3.1.2	28	None	0.1499	0.1763	25.1	N	-1.013	1.24	0.015087	-1.61	0.163	-0.8499	0.422359933901	1.19	0.999999	0.471	0.366277470483	0.993	0.503998935223	-0.8	0.24	0.359	0.118	None	None	1.97E-05	0	0	0	0	None	0	0	1.97E-05	4.41E-05	0	0	None	I	None
21192	16	I/V	rs758357424	0.1282	gnomAD-4.0.0	28	None	0.1499	0.1763	25.1	N	-1.013	1.24	0.015087	-1.61	0.163	-0.8499	0.422359933901	1.19	0.999999	0.471	0.366277470483	0.993	0.503998935223	-0.8	0.24	0.359	0.118	None	None	1.97371E-05	0	0	0	0	None	0	0	1.97371E-05	4.41462E-05	0	0	None	I	None
21193	17	R/C	rs376800688	0.6527	gnomAD-2.1.1	29	None	0.6461	0.5574	None	N	-0.594	None	None	-0.528	None	None	None	None	None	None	None	1.0	None	None	0.366	0.739	None	None	None	2.86899E-04	0	2.84E-05	0	0	None	0	None	2.86899E-04	4.02E-05	5.96556E-04	2.82566E-04	None	I	None
21193	17	R/C	rs376800688	0.6527	gnomAD-3.1.2	29	None	0.6461	0.5574	None	N	-0.594	None	None	-0.528	None	None	None	None	None	None	None	1.0	None	None	0.366	0.739	None	None	None	3.35597E-04	1.69074E-04	3.93597E-04	0	0	None	0	3.16456E-03	3.35597E-04	5.44438E-04	0	0	None	I	None
21193	17	R/C	rs376800688	0.6527	gnomAD-4.0.0	29	None	0.6461	0.5574	None	N	-0.594	None	None	-0.528	None	None	None	None	None	None	None	1.0	None	None	0.366	0.739	None	None	None	4.51428E-04	1.06732E-04	1.16799E-04	0	0	None	6.25508E-05	1.65399E-04	4.51428E-04	5.79169E-04	3.29736E-05	3.52429E-04	None	I	None
21193	17	R/H	rs372267046	0.6527	gnomAD-2.1.1	29	None	0.3722	0.3043	None	N	-1.142	None	None	-0.919	None	None	None	None	None	None	None	1.0	None	None	0.432	0.765	None	None	None	7.89E-05	4.14E-05	8.52E-05	0	0	None	1.31027E-04	None	7.89E-05	0	7.07E-05	7.06614E-04	None	I	None
21193	17	R/H	rs372267046	0.6527	gnomAD-3.1.2	29	None	0.3722	0.3043	None	N	-1.142	None	None	-0.919	None	None	None	None	None	None	None	1.0	None	None	0.432	0.765	None	None	None	7.24E-05	7.25E-05	2.62433E-04	0	1.94401E-04	None	0	0	7.24E-05	2.94E-05	0	4.78927E-04	None	I	None
21193	17	R/H	rs372267046	0.6527	gnomAD-4.0.0	29	None	0.3722	0.3043	None	N	-1.142	None	None	-0.919	None	None	None	None	None	None	None	1.0	None	None	0.432	0.765	None	None	None	9.1164E-05	5.34559E-05	1.00164E-04	0	2.23964E-05	None	0	8.23995E-04	9.1164E-05	9.66716E-05	1.20892E-04	9.61508E-05	None	I	None
21194	18	L/P	rs367838375	0.1258	gnomAD-2.1.1	30	None	0.9922	0.9899	None	D	-1.82	None	None	-0.793	None	None	None	None	None	None	None	1.0	None	None	0.829	0.865	None	None	None	4.66E-05	0	0	0	0	None	0	None	4.66E-05	0	1.01998E-04	0	None	I	None
21194	18	L/P	rs367838375	0.1258	gnomAD-3.1.2	30	None	0.9922	0.9899	None	D	-1.82	None	None	-0.793	None	None	None	None	None	None	None	1.0	None	None	0.829	0.865	None	None	None	5.92E-05	0	0	0	0	None	0	0	5.92E-05	1.32411E-04	0	0	None	I	None
21194	18	L/P	rs367838375	0.1258	gnomAD-4.0.0	30	None	0.9922	0.9899	None	D	-1.82	None	None	-0.793	None	None	None	None	None	None	None	1.0	None	None	0.829	0.865	None	None	None	1.61219E-05	0	0	0	0	None	0	0	1.61219E-05	2.20464E-05	0	0	None	I	None
21194	18	L/V	None	0.1258	gnomAD-4.0.0	30	None	0.3358	0.3372	24.9	D	None	-0.89	0.037594	-0.793	0.627	0.3593	0.465770963553	2.515	0.999999	0.638	0.773388115084	0.999	0.736056447029	-2.27	0.589	0.629	0.008	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
21196	20	A/G	rs1460483373	0.2449	gnomAD-4.0.0	33	None	0.1514	0.2469	34.0	N	None	0.9	0.013728	-1.029	0.2356	-0.7077	0.464868906428	2.22	1.0	0.684	0.335164054921	1.0	0.633572816849	-3.17	0.351	0.708	0.002	None	None	1.59346E-06	0	0	0	2.78707E-05	None	0	0	1.59346E-06	0	0	0	None	N	None
21197	21	I/T	rs1473107263	0.6315	gnomAD-3.1.2	34	None	0.1525	0.1595	24.3	N	None	-0.05	0.050626	-0.723	0.0797	-0.9837	0.107737316608	-0.83	0.716646	0.418	0.59202398213	0.002	0.560180783272	-1.58	0.088	0.24	1.0	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
21197	21	I/T	rs1473107263	0.6315	gnomAD-4.0.0	34	None	0.1525	0.1595	24.3	N	None	-0.05	0.050626	-0.723	0.0797	-0.9837	0.107737316608	-0.83	0.716646	0.418	0.59202398213	0.002	0.560180783272	-1.58	0.088	0.24	1.0	None	None	7.69578E-06	0	0	0	0	None	0	0	7.69578E-06	1.19771E-05	0	2.84787E-05	None	I	None
21197	21	I/V	rs72646855	0.6315	gnomAD-2.1.1	34	None	0.0687	0.0705	None	N	-0.902	None	None	-0.518	None	None	None	None	None	None	None	0.002	None	None	0.082	0.146	None	None	None	6.05522E-04	1.65494E-04	1.70174E-04	0	0	None	7.52322E-04	None	6.05522E-04	3.60808E-04	9.88359E-04	1.41203E-04	None	I	None
21197	21	I/V	rs72646855	0.6315	gnomAD-3.1.2	34	None	0.0687	0.0705	None	N	-0.902	None	None	-0.518	None	None	None	None	None	None	None	0.002	None	None	0.082	0.146	None	None	None	5.45866E-04	2.65457E-04	1.96773E-04	0	0	None	1.88253E-04	0	5.45866E-04	9.70874E-04	2.06954E-04	0	None	I	None
21197	21	I/V	rs72646855	0.6315	gnomAD-4.0.0	34	None	0.0687	0.0705	None	N	-0.902	None	None	-0.518	None	None	None	None	None	None	None	0.002	None	None	0.082	0.146	None	None	None	7.41523E-04	2.00048E-04	2.0018E-04	0	4.48009E-05	None	3.90747E-04	0	7.41523E-04	8.83527E-04	6.81154E-04	6.08623E-04	None	I	None
21198	22	V/A	None	0.1945	gnomAD-4.0.0	35	None	0.6278	0.6151	24.9	N	None	-0.76	0.043387	-1.323	0.3718	-0.2509	0.254955273701	0.92	0.999969	0.627	0.699911873028	0.78	0.721994161606	-3.13	0.496	0.648	0.005	None	None	1.59332E-06	0	0	0	0	None	0	0	1.59332E-06	0	1.43406E-05	0	None	I	None
21198	22	V/G	rs1559553614	0.1945	gnomAD-2.1.1	35	None	0.7551	0.7385	28.7	D	None	-0.93	0.056133	-1.674	0.6354	0.4669	0.445673333928	2.415	1.0	0.685	0.88472872791	0.995	0.623519778252	-5.53	0.653	0.837	0.002	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.92E-06	0	None	I	None
21198	22	V/G	rs1559553614	0.1945	gnomAD-4.0.0	35	None	0.7551	0.7385	28.7	D	None	-0.93	0.056133	-1.674	0.6354	0.4669	0.445673333928	2.415	1.0	0.685	0.88472872791	0.995	0.623519778252	-5.53	0.653	0.837	0.002	None	None	1.59332E-06	0	0	0	0	None	0	0	1.59332E-06	2.86125E-06	0	0	None	I	None
21198	22	V/L	None	0.1945	gnomAD-4.0.0	35	None	0.345	0.2929	21.9	D	None	-0.84	0.0446	-0.447	0.3686	-0.291	0.129028637738	1.645	0.999359	0.593	0.552085806491	0.437	0.702391624451	-1.8	0.36	0.461	0.04	None	None	6.84584E-07	0	0	0	0	None	1.8742E-05	0	6.84584E-07	0	0	0	None	I	None
21198	22	V/M	None	0.1945	gnomAD-4.0.0	35	None	0.3968	0.3514	23.3	D	None	-0.91	0.046461	-0.523	0.6013	0.3695	0.393936689695	2.615	0.999497	0.548	0.69131558434	0.968	0.730776429176	-2.07	0.596	0.704	0.007	None	None	6.84584E-07	0	0	0	0	None	0	0	6.84584E-07	8.99769E-07	0	0	None	I	None
21200	24	G/E	rs1313160165	0.3438	gnomAD-2.1.1	40	None	0.9967	0.9963	27.6	D	-0.901	-1.14	0.143219	-1.089	0.8126	0.9192	0.526218639335	4.51	1.0	0.87	0.731956435446	1.0	0.787407755852	-6.4	0.824	0.809	0.003	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.92E-06	0	None	I	None
21200	24	G/E	rs1313160165	0.3438	gnomAD-4.0.0	40	None	0.9967	0.9963	27.6	D	-0.901	-1.14	0.143219	-1.089	0.8126	0.9192	0.526218639335	4.51	1.0	0.87	0.731956435446	1.0	0.787407755852	-6.4	0.824	0.809	0.003	None	None	6.37284E-06	0	0	0	0	None	0	0	6.37284E-06	1.14449E-05	0	0	None	I	None
21200	24	G/R	None	0.3438	gnomAD-4.0.0	40	None	0.996	0.9956	33.0	D	None	-1.32	0.095499	-0.567	0.8218	0.9009	0.506463245118	4.51	1.0	0.877	0.81583949607	1.0	0.797392845154	-6.4	0.834	0.81	0.002	None	None	3.1865E-06	0	0	0	0	None	1.88388E-05	0	3.1865E-06	2.8612E-06	0	0	None	I	None
21201	25	R/L	None	0.7225	gnomAD-4.0.0	41	None	0.8406	0.8161	27.1	N	None	-0.24	0.044669	0.496	0.5147	0.0206	0.516030974754	2.385	1.0	0.607	0.747437394213	1.0	0.625812530518	-5.5	0.502	0.638	0.003	None	None	6.84595E-07	0	0	0	0	None	0	0	6.84595E-07	0	0	1.65777E-05	None	I	None
21201	25	R/Q	rs763273464	0.7225	gnomAD-2.1.1	41	None	0.4215	0.3721	27.3	N	0.018	-0.21	0.030683	0.074	0.5147	0.0206	0.496624975885	2.205	1.0	0.566	0.437420747294	1.0	0.551617324352	-3.1	0.438	0.719	0.006	None	None	2.42E-05	0	8.72E-05	0	0	None	0	None	2.42E-05	9.31E-05	8.92E-06	0	None	I	None
21201	25	R/Q	rs763273464	0.7225	gnomAD-3.1.2	41	None	0.4215	0.3721	27.3	N	0.018	-0.21	0.030683	0.074	0.5147	0.0206	0.496624975885	2.205	1.0	0.566	0.437420747294	1.0	0.551617324352	-3.1	0.438	0.719	0.006	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
21201	25	R/Q	rs763273464	0.7225	gnomAD-4.0.0	41	None	0.4215	0.3721	27.3	N	0.018	-0.21	0.030683	0.074	0.5147	0.0206	0.496624975885	2.205	1.0	0.566	0.437420747294	1.0	0.551617324352	-3.1	0.438	0.719	0.006	None	None	1.17811E-05	2.67173E-05	5.00617E-05	0	2.24014E-05	None	3.12656E-05	0	1.17811E-05	8.47906E-06	1.09876E-05	0	None	I	None
21202	26	P/S	rs752725604	0.5243	gnomAD-2.1.1	42	None	0.9655	0.9648	27.0	D	-0.077	-0.79	0.081878	-0.507	0.7599	0.7909	0.466644225527	4.035	1.0	0.741	0.600640161457	1.0	0.654700875282	-6.4	0.783	0.661	None	None	None	4.04E-06	0	0	0	0	None	3.27E-05	None	4.04E-06	0	0	0	None	I	None
21202	26	P/S	rs752725604	0.5243	gnomAD-4.0.0	42	None	0.9655	0.9648	27.0	D	-0.077	-0.79	0.081878	-0.507	0.7599	0.7909	0.466644225527	4.035	1.0	0.741	0.600640161457	1.0	0.654700875282	-6.4	0.783	0.661	None	None	None	2.73823E-06	0	0	0	0	None	0	0	2.73823E-06	2.69925E-06	1.15988E-05	0	None	I	None
21202	26	P/T	None	0.5243	gnomAD-4.0.0	42	None	0.9108	0.9041	26.5	D	None	-0.83	0.086219	-0.545	0.7822	0.8702	0.48919594472	4.58	1.0	0.755	0.641703553165	1.0	0.678709626198	-6.4	0.757	0.657	None	None	None	6.84558E-07	0	0	0	0	None	0	0	6.84558E-07	8.9975E-07	0	0	None	I	None
21203	27	A/D	rs544707116	0.5791	gnomAD-2.1.1	43	None	0.3462	0.2933	25.2	N	-0.757	-0.17	0.059623	-0.797	0.3294	-0.362	0.324948871976	1.765	0.999232	0.491	0.575814496085	0.901	0.527399301529	-3.71	0.402	0.631	0.04	None	None	8.07E-06	1.294E-04	0	0	0	None	0	None	8.07E-06	0	0	0	None	I	None
21203	27	A/D	rs544707116	0.5791	gnomAD-3.1.2	43	None	0.3462	0.2933	25.2	N	-0.757	-0.17	0.059623	-0.797	0.3294	-0.362	0.324948871976	1.765	0.999232	0.491	0.575814496085	0.901	0.527399301529	-3.71	0.402	0.631	0.04	None	None	1.97E-05	7.25E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	I	None
21203	27	A/D	rs544707116	0.5791	1000 genomes	43	None	0.3462	0.2933	25.2	N	-0.757	-0.17	0.059623	-0.797	0.3294	-0.362	0.324948871976	1.765	0.999232	0.491	0.575814496085	0.901	0.527399301529	-3.71	0.402	0.631	0.04	None	None	5.99042E-04	2.3E-03	0	None	0	0	None	None	5.99042E-04	None	0	None	None	I	None
21203	27	A/D	rs544707116	0.5791	gnomAD-4.0.0	43	None	0.3462	0.2933	25.2	N	-0.757	-0.17	0.059623	-0.797	0.3294	-0.362	0.324948871976	1.765	0.999232	0.491	0.575814496085	0.901	0.527399301529	-3.71	0.402	0.631	0.04	None	None	1.31527E-05	4.81835E-05	0	0	0	None	0	0	1.31527E-05	0	0	0	None	I	None
21205	29	K/E	rs794727409	0.7107	gnomAD-2.1.1	45	None	0.1824	0.1473	24.5	N	0.384	-0.17	0.028754	0.057	0.1568	-0.7346	0.237924470368	0.935	0.999995	0.516	0.303781844768	0.41	0.497329592705	-2.85	0.283	0.576	0.291	None	None	7.16E-06	0	2.84E-05	0	0	None	0	None	7.16E-06	0	7.84E-06	0	None	I	None
21205	29	K/E	rs794727409	0.7107	gnomAD-3.1.2	45	None	0.1824	0.1473	24.5	N	0.384	-0.17	0.028754	0.057	0.1568	-0.7346	0.237924470368	0.935	0.999995	0.516	0.303781844768	0.41	0.497329592705	-2.85	0.283	0.576	0.291	None	None	1.97E-05	2.41E-05	0	0	0	None	0	0	1.97E-05	2.94E-05	0	0	None	I	None
21205	29	K/E	rs794727409	0.7107	gnomAD-4.0.0	45	None	0.1824	0.1473	24.5	N	0.384	-0.17	0.028754	0.057	0.1568	-0.7346	0.237924470368	0.935	0.999995	0.516	0.303781844768	0.41	0.497329592705	-2.85	0.283	0.576	0.291	None	None	6.20028E-06	1.33622E-05	1.66856E-05	0	0	None	0	0	6.20028E-06	6.78306E-06	0	0	None	I	None
21205	29	K/I	rs886042512	0.7107	gnomAD-2.1.1	45	None	0.3573	0.3161	25.5	N	0.863	-0.34	0.041673	0.588	0.3691	-0.4213	0.518132348203	1.94	0.99998	0.534	0.523082183605	0.908	0.474628984928	-5.81	0.392	0.737	0.006	None	None	1.21E-05	0	8.72E-05	0	0	None	0	None	1.21E-05	0	0	0	None	I	None
21205	29	K/I	rs886042512	0.7107	gnomAD-4.0.0	45	None	0.3573	0.3161	25.5	N	0.863	-0.34	0.041673	0.588	0.3691	-0.4213	0.518132348203	1.94	0.99998	0.534	0.523082183605	0.908	0.474628984928	-5.81	0.392	0.737	0.006	None	None	4.7792E-06	0	6.8653E-05	0	0	None	0	0	4.7792E-06	0	0	0	None	I	None
21205	29	K/N	rs771189924	0.7107	gnomAD-2.1.1	45	None	0.4137	0.3452	28.1	N	0.093	-0.3	0.020484	-0.015	0.3072	-0.4779	0.3237994763	1.34	0.99996	0.48	0.310458034454	0.83	0.517534434795	-3.48	0.215	0.693	0.015	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	I	None
21205	29	K/N	rs771189924	0.7107	gnomAD-4.0.0	45	None	0.4137	0.3452	28.1	N	0.093	-0.3	0.020484	-0.015	0.3072	-0.4779	0.3237994763	1.34	0.99996	0.48	0.310458034454	0.83	0.517534434795	-3.48	0.215	0.693	0.015	None	None	1.59312E-06	0	0	0	0	None	0	0	1.59312E-06	0	1.43361E-05	0	None	I	None
21206	30	V/A	rs370145029	0.2728	gnomAD-2.1.1	46	None	0.452	0.397	None	D	-1.768	None	None	-1.773	None	None	None	None	None	None	None	0.977	None	None	0.688	0.64	None	None	None	2.15E-05	2.48262E-04	0	0	0	None	0	None	2.15E-05	0	0	0	None	I	None
21206	30	V/A	rs370145029	0.2728	gnomAD-3.1.2	46	None	0.452	0.397	None	D	-1.768	None	None	-1.773	None	None	None	None	None	None	None	0.977	None	None	0.688	0.64	None	None	None	5.27E-05	1.93274E-04	0	0	0	None	0	0	5.27E-05	0	0	0	None	I	None
21206	30	V/A	rs370145029	0.2728	1000 genomes	46	None	0.452	0.397	None	D	-1.768	None	None	-1.773	None	None	None	None	None	None	None	0.977	None	None	0.688	0.64	None	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	I	None
21206	30	V/A	rs370145029	0.2728	gnomAD-4.0.0	46	None	0.452	0.397	None	D	-1.768	None	None	-1.773	None	None	None	None	None	None	None	0.977	None	None	0.688	0.64	None	None	None	8.68012E-06	1.73463E-04	0	0	0	None	0	0	8.68012E-06	0	0	1.60185E-05	None	I	None
21206	30	V/D	None	0.2728	gnomAD-4.0.0	46	None	0.9356	0.8955	32.0	D	None	-1.08	0.15272	-1.815	0.7623	0.8289	0.569153236508	4.135	1.0	0.753	0.92510636424	0.999	0.673876404762	-5.43	0.88	0.867	None	None	None	6.84545E-07	0	0	0	0	None	0	0	6.84545E-07	8.99732E-07	0	0	None	I	None
21206	30	V/I	None	0.2728	gnomAD-4.0.0	46	None	0.0941	0.0991	24.0	N	None	-0.64	0.01993	-0.584	0.227	-0.7227	0.080742506992	0.93	0.999969	0.647	0.601658297244	0.117	0.523546993732	-0.8	0.168	0.315	0.262	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	0	3.66327E-05	None	I	None
21207	31	T/P	None	0.3912	gnomAD-4.0.0	47	None	0.627	0.6084	26.4	D	None	-0.35	0.041445	-0.3	0.6225	0.5221	0.516822102256	3.71	0.998502	0.609	0.498705051145	1.0	0.547139763832	-4.33	0.604	0.727	0.016	None	None	1.59309E-06	0	0	0	0	None	0	0	1.59309E-06	2.86085E-06	0	0	None	I	None
21209	33	R/Q	rs148684589	0.4349	gnomAD-2.1.1	49	None	0.1198	0.1129	None	N	-0.989	None	None	-0.41	None	None	None	None	None	None	None	0.98	None	None	0.187	0.536	None	None	None	1.00297E-04	5.37768E-04	0	0	5.19E-05	None	3.27E-05	None	1.00297E-04	0	7.84E-05	4.2337E-04	None	I	None
21209	33	R/Q	rs148684589	0.4349	gnomAD-3.1.2	49	None	0.1198	0.1129	None	N	-0.989	None	None	-0.41	None	None	None	None	None	None	None	0.98	None	None	0.187	0.536	None	None	None	1.51344E-04	4.3472E-04	6.56E-05	0	0	None	0	0	1.51344E-04	5.89E-05	0	0	None	I	None
21209	33	R/Q	rs148684589	0.4349	1000 genomes	49	None	0.1198	0.1129	None	N	-0.989	None	None	-0.41	None	None	None	None	None	None	None	0.98	None	None	0.187	0.536	None	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	I	None
21209	33	R/Q	rs148684589	0.4349	gnomAD-4.0.0	49	None	0.1198	0.1129	None	N	-0.989	None	None	-0.41	None	None	None	None	None	None	None	0.98	None	None	0.187	0.536	None	None	None	7.37808E-05	3.73543E-04	5.00501E-05	0	2.46537E-04	None	0	0	7.37808E-05	5.68085E-05	7.68893E-05	4.80523E-05	None	I	None
21211	35	V/A	rs397517654	0.4848	gnomAD-4.0.0	51	None	0.1293	0.1255	25.4	N	None	1.07	0.009784	-0.754	0.0609	-0.9793	0.191058906287	0.035	0.996107	0.516	0.367042808489	0.565	0.517388939857	-2.6	0.225	0.434	0.448	None	None	2.05364E-06	0	0	0	0	None	0	0	2.05364E-06	2.69916E-06	0	0	None	I	None
21211	35	V/I	None	0.4848	gnomAD-4.0.0	51	None	0.0899	0.0936	22.3	N	None	1.02	0.007196	-0.292	0.0908	-0.9331	0.0743878876887	0.515	0.76621	0.519	0.26169431596	0.034	0.411734730005	-0.53	0.036	0.347	0.314	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
21212	36	G/S	rs1381842230	0.6565	gnomAD-4.0.0	52	None	0.2539	0.2678	27.4	N	-0.742	0.55	0.015767	-0.747	0.3992	-0.2478	0.463496485926	2.795	1.0	0.753	0.341460817117	1.0	0.672437906265	-4.57	0.527	0.687	0.072	None	None	1.3691E-06	0	0	0	0	None	0	0	1.3691E-06	8.99722E-07	0	1.65766E-05	None	I	None
21213	37	I/M	None	0.5667	gnomAD-4.0.0	55	None	0.0953	0.0991	23.9	N	None	-0.25	0.023264	-0.391	0.1915	-0.8205	0.217292321299	1.365	0.99772	0.414	0.504541157375	0.81	0.544386982918	-1.93	0.107	0.411	0.027	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
21213	37	I/T	None	0.5667	gnomAD-4.0.0	55	None	0.1446	0.1648	26.0	N	None	-0.18	0.032233	-0.554	0.2344	-0.6275	0.178699121643	1.16	0.999989	0.462	0.687538048876	0.549	0.683015942574	-3.17	0.281	0.359	0.087	None	None	1.59312E-06	0	0	0	0	None	0	0	1.59312E-06	2.86076E-06	0	0	None	I	None
21213	37	I/V	rs2049329163	0.5667	gnomAD-3.1.2	55	None	0.0771	0.0804	22.2	N	None	-0.21	0.018831	-0.374	0.1566	-0.8725	0.0712667058525	0.335	0.996815	0.431	0.485776496936	0.007	0.493170887232	-0.5	0.063	0.204	0.401	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
21213	37	I/V	rs2049329163	0.5667	gnomAD-4.0.0	55	None	0.0771	0.0804	22.2	N	None	-0.21	0.018831	-0.374	0.1566	-0.8725	0.0712667058525	0.335	0.996815	0.431	0.485776496936	0.007	0.493170887232	-0.5	0.063	0.204	0.401	None	None	6.57834E-06	0	0	0	0	None	0	0	6.57834E-06	1.47124E-05	0	0	None	I	None
21214	38	D/A	rs779686062	1.1355	gnomAD-2.1.1	56	None	0.4021	0.3837	32.0	N	-0.074	-0.27	0.037991	0.1	0.4312	-0.1438	0.516030974754	1.615	1.0	0.574	0.486282253068	1.0	0.667361736298	-5.77	0.545	0.733	0.008	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.67E-05	0	None	I	None
21214	38	D/A	rs779686062	1.1355	gnomAD-4.0.0	56	None	0.4021	0.3837	32.0	N	-0.074	-0.27	0.037991	0.1	0.4312	-0.1438	0.516030974754	1.615	1.0	0.574	0.486282253068	1.0	0.667361736298	-5.77	0.545	0.733	0.008	None	None	1.2322E-05	2.99168E-05	0	0	0	None	0	0	1.2322E-05	1.25959E-05	0	4.97298E-05	None	I	None
21214	38	D/G	None	1.1355	gnomAD-4.0.0	56	None	0.367	0.3351	32.0	D	None	-0.34	0.029633	-0.01	0.4416	-0.1181	0.528847580626	2.01	1.0	0.518	0.413891365518	1.0	0.680499315262	-5.2	0.539	0.714	0.004	None	None	6.84554E-07	2.99168E-05	0	0	0	None	0	0	6.84554E-07	0	0	0	None	I	None
21214	38	D/N	rs746677565	1.1355	gnomAD-2.1.1	56	None	0.2208	0.2109	26.7	N	0.217	-0.31	0.019988	0.375	0.434	-0.2029	0.459178880736	1.445	1.0	0.538	0.374255764437	1.0	0.71808218956	-3.73	0.411	0.638	0.005	None	None	4.03E-06	6.47E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	I	None
21216	40	V/M	rs542681131	0.8389	gnomAD-2.1.1	59	None	0.3359	0.3402	27.4	N	-0.362	0.87	0.016978	-0.465	0.2535	-0.6772	0.465052223951	2.12	1.0	0.423	0.512595481341	1.0	0.754955768585	-2.13	0.293	0.619	0.03	None	None	2.82E-05	0	0	0	0	None	2.28938E-04	None	2.82E-05	0	0	0	None	I	None
21216	40	V/M	rs542681131	0.8389	gnomAD-3.1.2	59	None	0.3359	0.3402	27.4	N	-0.362	0.87	0.016978	-0.465	0.2535	-0.6772	0.465052223951	2.12	1.0	0.423	0.512595481341	1.0	0.754955768585	-2.13	0.293	0.619	0.03	None	None	3.29E-05	2.41E-05	0	0	0	None	0	0	3.29E-05	0	8.28157E-04	0	None	I	None
21216	40	V/M	rs542681131	0.8389	1000 genomes	59	None	0.3359	0.3402	27.4	N	-0.362	0.87	0.016978	-0.465	0.2535	-0.6772	0.465052223951	2.12	1.0	0.423	0.512595481341	1.0	0.754955768585	-2.13	0.293	0.619	0.03	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	I	None
21216	40	V/M	rs542681131	0.8389	gnomAD-4.0.0	59	None	0.3359	0.3402	27.4	N	-0.362	0.87	0.016978	-0.465	0.2535	-0.6772	0.465052223951	2.12	1.0	0.423	0.512595481341	1.0	0.754955768585	-2.13	0.293	0.619	0.03	None	None	1.98398E-05	1.33397E-05	0	0	0	None	0	0	1.98398E-05	0	3.29504E-04	1.60159E-05	None	I	None
21217	41	V/A	rs1351844757	0.2193	gnomAD-2.1.1	69	None	0.3233	0.3432	23.6	N	-0.647	-0.17	0.02107	-0.413	0.1425	-0.9536	0.101831540528	1.1	0.999965	0.466	0.374613414588	0.003	0.547419369221	-2.74	0.175	0.195	0.252	None	None	3.19E-05	1.14969E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	N	None
21217	41	V/A	rs1351844757	0.2193	gnomAD-3.1.2	69	None	0.3233	0.3432	23.6	N	-0.647	-0.17	0.02107	-0.413	0.1425	-0.9536	0.101831540528	1.1	0.999965	0.466	0.374613414588	0.003	0.547419369221	-2.74	0.175	0.195	0.252	None	None	1.32E-05	4.83E-05	0	0	0	None	0	0	1.32E-05	0	0	0	None	N	None
21217	41	V/A	rs1351844757	0.2193	gnomAD-4.0.0	69	None	0.3233	0.3432	23.6	N	-0.647	-0.17	0.02107	-0.413	0.1425	-0.9536	0.101831540528	1.1	0.999965	0.466	0.374613414588	0.003	0.547419369221	-2.74	0.175	0.195	0.252	None	None	3.84796E-06	5.08199E-05	0	0	0	None	0	0	3.84796E-06	0	0	0	None	N	None
21217	41	V/I	rs1214985099	0.2193	gnomAD-2.1.1	69	None	0.0756	0.0822	20.5	N	-0.235	-0.25	0.039462	-0.178	0.1754	-0.8605	0.0687624967998	0.67	0.99708	0.449	0.378322506985	0.001	0.40201997757	-0.57	0.127	0.147	0.33	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
21217	41	V/I	rs1214985099	0.2193	gnomAD-4.0.0	69	None	0.0756	0.0822	20.5	N	-0.235	-0.25	0.039462	-0.178	0.1754	-0.8605	0.0687624967998	0.67	0.99708	0.449	0.378322506985	0.001	0.40201997757	-0.57	0.127	0.147	0.33	None	None	1.5932E-06	0	0	0	0	None	0	0	1.5932E-06	0	1.43349E-05	0	None	N	None
21218	42	R/G	rs778966200	0.8492	gnomAD-2.1.1	70	None	0.4149	0.3967	29.1	N	-0.09	-0.27	0.041198	-0.046	0.406	-0.2204	0.523221014711	1.405	0.999927	0.58	0.524792858863	1.0	0.670691728592	-5.23	0.448	0.635	0.015	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
21218	42	R/G	rs778966200	0.8492	gnomAD-4.0.0	70	None	0.4149	0.3967	29.1	N	-0.09	-0.27	0.041198	-0.046	0.406	-0.2204	0.523221014711	1.405	0.999927	0.58	0.524792858863	1.0	0.670691728592	-5.23	0.448	0.635	0.015	None	None	2.05372E-06	0	0	0	0	None	0	0	2.05372E-06	2.69916E-06	0	0	None	N	None
21220	44	G/E	rs757154541	0.1842	gnomAD-2.1.1	102	None	0.9349	0.9328	27.8	N	-1.31	-0.26	0.03447	-1.051	0.4444	-0.1829	0.526218639335	1.755	1.0	0.644	0.668496244192	1.0	0.767881929874	-5.9	0.52	0.835	0.008	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.92E-06	0	None	N	None
21221	45	Q/H	None	0.6113	gnomAD-4.0.0	122	None	0.1976	0.197	23.3	N	None	-0.31	0.01097	-0.258	0.1492	-0.9565	0.0844159057736	-0.09	0.982197	0.522	0.101711395817	0.015	0.502993226051	-2.37	0.128	0.131	0.302	None	None	1.59339E-06	0	2.28906E-05	0	0	None	0	0	1.59339E-06	0	0	0	None	I	None
21221	45	Q/K	rs2049322891	0.6113	gnomAD-4.0.0	122	None	0.1265	0.1214	23.7	N	None	-0.15	0.036377	0.056	0.2629	-0.593	0.296777690307	0.31	0.999998	0.579	0.219573609325	0.826	0.514644503593	-2.27	0.246	0.376	0.327	None	None	1.5935E-06	0	0	0	0	None	0	0	1.5935E-06	2.86092E-06	0	0	None	I	None
21222	46	V/A	rs183595734	0.3172	gnomAD-2.1.1	123	None	0.3401	0.3065	None	D	-1.233	None	None	-1.317	None	None	None	None	None	None	None	0.999	None	None	0.613	0.521	None	None	None	1.07E-05	4.14E-05	0	0	5.2E-05	None	0	None	1.07E-05	0	7.84E-06	0	None	I	None
21222	46	V/A	rs183595734	0.3172	gnomAD-3.1.2	123	None	0.3401	0.3065	None	D	-1.233	None	None	-1.317	None	None	None	None	None	None	None	0.999	None	None	0.613	0.521	None	None	None	1.97E-05	2.41E-05	0	0	1.9478E-04	None	0	0	1.97E-05	1.47E-05	0	0	None	I	None
21222	46	V/A	rs183595734	0.3172	1000 genomes	123	None	0.3401	0.3065	None	D	-1.233	None	None	-1.317	None	None	None	None	None	None	None	0.999	None	None	0.613	0.521	None	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	I	None
21222	46	V/A	rs183595734	0.3172	gnomAD-4.0.0	123	None	0.3401	0.3065	None	D	-1.233	None	None	-1.317	None	None	None	None	None	None	None	0.999	None	None	0.613	0.521	None	None	None	7.44027E-06	1.33369E-05	0	3.38043E-05	2.24185E-05	None	0	0	7.44027E-06	4.23936E-06	3.29518E-05	1.6019E-05	None	I	None
21222	46	V/G	rs183595734	0.3172	gnomAD-3.1.2	123	None	0.4908	0.4353	32.0	N	None	-0.56	0.045973	-1.64	0.5927	0.3182	0.527292994097	2.59	1.0	0.682	0.928019228929	1.0	0.445144116879	-5.6	0.677	0.795	0.001	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
21222	46	V/G	rs183595734	0.3172	gnomAD-4.0.0	123	None	0.4908	0.4353	32.0	N	None	-0.56	0.045973	-1.64	0.5927	0.3182	0.527292994097	2.59	1.0	0.682	0.928019228929	1.0	0.445144116879	-5.6	0.677	0.795	0.001	None	None	2.48027E-06	5.34345E-05	0	0	0	None	0	0	2.48027E-06	0	0	0	None	I	None
21223	47	D/G	None	0.4684	gnomAD-4.0.0	125	None	0.7106	0.6369	32.0	N	None	-0.3	0.021835	-0.671	0.4835	0.0012	0.528847580626	2.49	1.0	0.535	0.40146981186	1.0	0.594033181667	-5.5	0.546	0.692	0.004	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
21223	47	D/H	rs753562502	0.4684	gnomAD-2.1.1	125	None	0.7417	0.6783	26.7	D	0.417	-0.28	0.019731	0.195	0.4653	-0.1371	0.503932569898	2.015	1.0	0.55	0.400468435593	1.0	0.655320644379	-5.43	0.502	0.646	0.002	None	None	7.17E-06	0	0	0	1.04015E-04	None	0	None	7.17E-06	0	0	0	None	I	None
21223	47	D/H	rs753562502	0.4684	gnomAD-3.1.2	125	None	0.7417	0.6783	26.7	D	0.417	-0.28	0.019731	0.195	0.4653	-0.1371	0.503932569898	2.015	1.0	0.55	0.400468435593	1.0	0.655320644379	-5.43	0.502	0.646	0.002	None	None	6.58E-06	0	0	0	1.94628E-04	None	0	0	6.58E-06	0	0	0	None	I	None
21223	47	D/H	rs753562502	0.4684	gnomAD-4.0.0	125	None	0.7417	0.6783	26.7	D	0.417	-0.28	0.019731	0.195	0.4653	-0.1371	0.503932569898	2.015	1.0	0.55	0.400468435593	1.0	0.655320644379	-5.43	0.502	0.646	0.002	None	None	2.48044E-06	0	0	0	4.4825E-05	None	0	0	2.48044E-06	1.69575E-06	0	0	None	I	None
21223	47	D/N	None	0.4684	gnomAD-4.0.0	125	None	0.4098	0.3434	26.9	D	None	-0.27	0.01697	-0.561	0.4758	-0.1115	0.459178880736	2.045	1.0	0.534	0.371157983038	1.0	0.635501682758	-3.9	0.448	0.589	0.005	None	None	2.05389E-06	0	0	0	0	None	0	0	2.05389E-06	2.69919E-06	0	0	None	I	None
21225	49	V/A	rs1396646735	0.4984	gnomAD-2.1.1	130	None	0.337	0.2863	26.3	N	-0.52	-0.21	0.024743	-0.714	0.2202	-0.6162	0.223827506895	0.23	0.99979	0.496	0.607687067698	0.822	0.538209974766	-2.84	0.28	0.384	0.012	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	4.67E-05	0	0	None	I	None
21225	49	V/A	rs1396646735	0.4984	gnomAD-4.0.0	130	None	0.337	0.2863	26.3	N	-0.52	-0.21	0.024743	-0.714	0.2202	-0.6162	0.223827506895	0.23	0.99979	0.496	0.607687067698	0.822	0.538209974766	-2.84	0.28	0.384	0.012	None	None	4.10775E-06	0	0	0	0	None	1.87829E-05	0	4.10775E-06	4.49865E-06	0	0	None	I	None
21225	49	V/I	rs777568221	0.4984	gnomAD-2.1.1	130	None	0.1044	0.0887	20.2	N	-0.103	-0.27	0.024998	-0.303	0.1671	-0.8912	0.0772688110211	-0.515	0.989243	0.489	0.346315397577	0.058	0.376175582409	-0.38	0.123	0.224	0.651	None	None	8.07E-06	0	2.91E-05	0	0	None	3.27E-05	None	8.07E-06	0	0	0	None	I	None
21225	49	V/I	rs777568221	0.4984	gnomAD-4.0.0	130	None	0.1044	0.0887	20.2	N	-0.103	-0.27	0.024998	-0.303	0.1671	-0.8912	0.0772688110211	-0.515	0.989243	0.489	0.346315397577	0.058	0.376175582409	-0.38	0.123	0.224	0.651	None	None	3.18719E-06	0	2.28938E-05	0	0	None	0	0	3.18719E-06	0	1.43349E-05	0	None	I	None
21226	50	D/G	rs879061715	0.8630	gnomAD-4.0.0	131	None	0.493	0.4242	None	N	None	None	None	-0.11	None	None	None	None	None	None	None	1.0	None	None	0.468	0.595	None	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	I	None
21227	51	T/A	rs752958666	0.5507	gnomAD-2.1.1	134	None	0.179	0.1533	None	N	-0.327	None	None	-0.553	None	None	None	None	None	None	None	0.999	None	None	0.442	0.586	None	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.92E-06	0	None	N	None
21227	51	T/A	rs752958666	0.5507	gnomAD-3.1.2	134	None	0.179	0.1533	None	N	-0.327	None	None	-0.553	None	None	None	None	None	None	None	0.999	None	None	0.442	0.586	None	None	None	1.32E-05	2.42E-05	0	0	0	None	0	0	1.32E-05	1.47E-05	0	0	None	N	None
21227	51	T/A	rs752958666	0.5507	gnomAD-4.0.0	134	None	0.179	0.1533	None	N	-0.327	None	None	-0.553	None	None	None	None	None	None	None	0.999	None	None	0.442	0.586	None	None	None	4.34069E-06	1.33629E-05	0	0	0	None	0	0	4.34069E-06	3.39152E-06	0	3.20482E-05	None	N	None
21227	51	T/P	None	0.5507	gnomAD-4.0.0	134	None	0.4034	0.3379	33.0	N	None	-0.27	0.021613	-0.16	0.4625	-0.0615	0.526341791039	2.08	1.0	0.578	0.633985563651	1.0	0.643468797207	-4.67	0.521	0.702	0.042	None	None	6.84621E-07	0	0	0	0	None	0	0	6.84621E-07	8.99722E-07	0	0	None	N	None
21227	51	T/S	rs752958666	0.5507	gnomAD-3.1.2	134	None	0.1555	0.1319	33.0	N	None	-0.17	0.017984	-0.741	0.2523	-0.3634	0.441239122942	0.6	1.0	0.468	0.472741223727	0.999	0.657724320889	-3.1	0.36	0.619	0.359	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
21227	51	T/S	rs752958666	0.5507	gnomAD-4.0.0	134	None	0.1555	0.1319	33.0	N	None	-0.17	0.017984	-0.741	0.2523	-0.3634	0.441239122942	0.6	1.0	0.468	0.472741223727	0.999	0.657724320889	-3.1	0.36	0.619	0.359	None	None	6.57964E-06	0	0	0	0	None	0	0	6.57964E-06	1.4715E-05	0	0	None	N	None
21228	52	M/K	None	0.2491	gnomAD-4.0.0	135	None	0.5816	0.55	29.7	N	None	-0.11	0.017989	-0.953	0.2875	-0.4174	0.567138394775	0.12	1.0	0.586	0.808737173022	0.994	0.652153491974	-4.17	0.526	0.563	0.204	None	None	6.84639E-07	0	0	0	0	None	0	0	6.84639E-07	0	0	1.65793E-05	None	N	None
21228	52	M/T	rs1397983700	0.2491	gnomAD-2.1.1	135	None	0.5441	0.4543	28.2	N	None	-0.11	0.018235	-1.435	0.2962	-0.4118	0.488469659113	0.325	1.0	0.517	0.812414231654	0.994	0.686856329441	-4.4	0.512	0.563	0.144	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.92E-06	0	None	N	None
21228	52	M/T	rs1397983700	0.2491	gnomAD-4.0.0	135	None	0.5441	0.4543	28.2	N	None	-0.11	0.018235	-1.435	0.2962	-0.4118	0.488469659113	0.325	1.0	0.517	0.812414231654	0.994	0.686856329441	-4.4	0.512	0.563	0.144	None	None	6.84639E-07	0	0	0	0	None	0	0	6.84639E-07	8.99724E-07	0	0	None	N	None
21228	52	M/V	None	0.2491	gnomAD-4.0.0	135	None	0.2001	0.1678	25.2	N	None	-0.18	0.007855	-1.299	0.2973	-0.4108	0.455994801244	0.49	1.0	0.556	0.703477315268	0.985	0.523650169373	-3.0	0.446	0.45	0.184	None	None	1.36927E-06	0	0	0	0	None	0	0	1.36927E-06	1.79946E-06	0	0	None	N	None
21229	53	A/V	rs1209410552	0.0891	gnomAD-3.1.2	136	None	0.2928	0.2483	27.4	N	None	1.01	0.033011	0.421	0.1444	-0.9298	0.264892400789	0.84	0.999991	0.54	0.350088858571	0.961	0.648402273655	-2.27	0.222	0.705	0.017	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
21229	53	A/V	rs1209410552	0.0891	gnomAD-4.0.0	136	None	0.2928	0.2483	27.4	N	None	1.01	0.033011	0.421	0.1444	-0.9298	0.264892400789	0.84	0.999991	0.54	0.350088858571	0.961	0.648402273655	-2.27	0.222	0.705	0.017	None	None	1.02638E-05	0	1.69727E-05	0	9.76276E-05	None	0	0	1.02638E-05	7.18522E-06	0	0	None	N	None
21232	56	V/I	rs767582181	0.2582	gnomAD-2.1.1	139	None	0.0991	0.1053	22.5	N	-0.28	-0.21	0.034093	-0.656	0.2313	-0.6154	0.10609617995	1.16	0.999976	0.458	0.474248596982	0.767	0.555743217468	-0.7	0.185	0.321	0.133	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.92E-06	0	None	I	None
21232	56	V/I	rs767582181	0.2582	gnomAD-4.0.0	139	None	0.0991	0.1053	22.5	N	-0.28	-0.21	0.034093	-0.656	0.2313	-0.6154	0.10609617995	1.16	0.999976	0.458	0.474248596982	0.767	0.555743217468	-0.7	0.185	0.321	0.133	None	None	6.84705E-07	0	0	0	0	None	0	0	6.84705E-07	8.99748E-07	0	0	None	I	None
21232	56	V/L	None	0.2582	gnomAD-4.0.0	139	None	0.2818	0.373	23.9	N	None	-0.24	0.023477	-0.656	0.3474	-0.3833	0.27893692603	0.785	0.999993	0.483	0.593771126905	0.981	0.689001917839	-2.07	0.262	0.438	0.073	None	None	6.84705E-07	2.9915E-05	0	0	0	None	0	0	6.84705E-07	0	0	0	None	I	None
21233	57	I/M	None	0.1081	gnomAD-4.0.0	140	None	0.4145	0.4507	23.5	D	None	-1.23	0.022681	-0.862	0.6867	0.4686	0.468134351491	3.27	0.999533	0.742	0.704424639576	1.0	0.767470002174	-2.23	0.651	0.783	0.003	None	None	6.84706E-07	0	0	0	0	None	0	0	6.84706E-07	8.99751E-07	0	0	None	N	None
21233	57	I/T	None	0.1081	gnomAD-4.0.0	140	None	0.9595	0.9652	29.1	D	None	-1.28	0.056043	-2.409	0.7596	0.7416	0.51877166463	3.27	1.0	0.751	0.873723102753	1.0	0.836187303066	-3.8	0.782	0.823	0.002	None	None	6.84678E-07	0	0	0	0	None	0	0	6.84678E-07	8.99743E-07	0	0	None	N	None
21234	58	P/L	None	0.4596	gnomAD-4.0.0	141	None	0.316	0.3531	34.0	N	None	-0.2	0.025688	-0.423	0.3421	-0.4114	0.351260519606	1.885	1.0	0.463	0.58951732002	0.982	0.735056996346	-7.7	0.482	0.659	0.009	None	None	1.59405E-06	0	0	0	2.79174E-05	None	0	0	1.59405E-06	0	0	0	None	I	None
21234	58	P/S	rs1335943731	0.4596	gnomAD-2.1.1	141	None	0.211	0.2477	29.5	N	-1.237	-0.1	0.022503	-0.88	0.2291	-0.6502	0.274214619387	1.215	0.999747	0.356	0.391156786388	0.885	0.679534077644	-5.97	0.262	0.509	0.175	None	None	3.19E-05	1.14758E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	I	None
21234	58	P/S	rs1335943731	0.4596	gnomAD-3.1.2	141	None	0.211	0.2477	29.5	N	-1.237	-0.1	0.022503	-0.88	0.2291	-0.6502	0.274214619387	1.215	0.999747	0.356	0.391156786388	0.885	0.679534077644	-5.97	0.262	0.509	0.175	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
21234	58	P/S	rs1335943731	0.4596	gnomAD-4.0.0	141	None	0.211	0.2477	29.5	N	-1.237	-0.1	0.022503	-0.88	0.2291	-0.6502	0.274214619387	1.215	0.999747	0.356	0.391156786388	0.885	0.679534077644	-5.97	0.262	0.509	0.175	None	None	3.04544E-06	5.24512E-05	0	0	0	None	0	0	3.04544E-06	0	0	0	None	I	None
21235	59	N/D	rs786205305	0.7306	gnomAD-2.1.1	143	None	0.1152	0.1062	23.1	N	-0.074	0.93	0.027901	-0.003	0.0763	-1.0434	0.0953522573917	-0.015	0.986514	0.573	0.158396225186	None	0.397756576538	-1.73	0.075	0.13	0.573	None	None	4.04E-06	0	0	0	0	None	3.27E-05	None	4.04E-06	0	0	0	None	N	None
21235	59	N/D	rs786205305	0.7306	gnomAD-4.0.0	143	None	0.1152	0.1062	23.1	N	-0.074	0.93	0.027901	-0.003	0.0763	-1.0434	0.0953522573917	-0.015	0.986514	0.573	0.158396225186	None	0.397756576538	-1.73	0.075	0.13	0.573	None	None	1.59381E-06	0	0	0	0	None	0	0	1.59381E-06	0	1.43361E-05	0	None	N	None
21235	59	N/S	rs751607765	0.7306	gnomAD-2.1.1	143	None	0.0763	0.0774	24.2	N	-0.097	0.9	0.010766	-0.119	0.1363	-0.9473	0.0843968252718	0.895	0.99937	0.511	0.15556083564	0.042	0.331070482731	-2.73	0.159	0.356	0.115	None	None	2.15E-05	0	0	0	0	None	1.30933E-04	None	2.15E-05	0	1.57E-05	0	None	N	None
21235	59	N/S	rs751607765	0.7306	gnomAD-3.1.2	143	None	0.0763	0.0774	24.2	N	-0.097	0.9	0.010766	-0.119	0.1363	-0.9473	0.0843968252718	0.895	0.99937	0.511	0.15556083564	0.042	0.331070482731	-2.73	0.159	0.356	0.115	None	None	3.95E-05	0	0	0	0	None	0	0	3.95E-05	4.41E-05	6.20604E-04	0	None	N	None
21235	59	N/S	rs751607765	0.7306	gnomAD-4.0.0	143	None	0.0763	0.0774	24.2	N	-0.097	0.9	0.010766	-0.119	0.1363	-0.9473	0.0843968252718	0.895	0.99937	0.511	0.15556083564	0.042	0.331070482731	-2.73	0.159	0.356	0.115	None	None	2.10844E-05	0	0	0	2.24185E-05	None	0	1.64853E-04	2.10844E-05	4.23955E-06	2.85576E-04	1.60246E-05	None	N	None
21237	61	T/A	rs766847414	0.3516	gnomAD-2.1.1	145	None	0.1237	0.1339	25.6	N	-0.54	-0.24	0.015013	-0.668	0.3442	-0.3398	0.326445427642	1.955	0.999998	0.342	0.346544149963	0.962	0.617435097694	-3.53	0.282	0.497	0.03	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.48E-05	0	None	N	None
21237	61	T/A	rs766847414	0.3516	gnomAD-3.1.2	145	None	0.1237	0.1339	25.6	N	-0.54	-0.24	0.015013	-0.668	0.3442	-0.3398	0.326445427642	1.955	0.999998	0.342	0.346544149963	0.962	0.617435097694	-3.53	0.282	0.497	0.03	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	N	None
21237	61	T/A	rs766847414	0.3516	gnomAD-4.0.0	145	None	0.1237	0.1339	25.6	N	-0.54	-0.24	0.015013	-0.668	0.3442	-0.3398	0.326445427642	1.955	0.999998	0.342	0.346544149963	0.962	0.617435097694	-3.53	0.282	0.497	0.03	None	None	4.34125E-06	0	0	0	0	None	0	0	4.34125E-06	5.93555E-06	0	0	None	N	None
21237	61	T/I	None	0.3516	gnomAD-4.0.0	145	None	0.3891	0.4287	33.0	N	None	-0.31	0.025407	-0.322	0.4978	-0.0425	0.466674898207	2.145	1.0	0.396	0.541962755691	0.999	0.728313803673	-4.47	0.418	0.803	0.008	None	None	1.20033E-06	0	0	0	0	None	0	0	1.20033E-06	1.31252E-06	0	0	None	N	None
21238	62	R/C	rs190432620	0.7666	gnomAD-2.1.1	146	None	0.7639	0.7798	None	D	-0.03	None	None	-0.131	None	None	None	None	None	None	None	1.0	None	None	0.384	0.731	None	None	None	2.02E-05	6.48E-05	0	0	0	None	6.55E-05	None	2.02E-05	0	8.93E-06	1.67168E-04	None	I	None
21238	62	R/C	rs190432620	0.7666	gnomAD-3.1.2	146	None	0.7639	0.7798	None	D	-0.03	None	None	-0.131	None	None	None	None	None	None	None	1.0	None	None	0.384	0.731	None	None	None	2.63E-05	2.42E-05	0	0	0	None	0	0	2.63E-05	4.41E-05	0	0	None	I	None
21238	62	R/C	rs190432620	0.7666	1000 genomes	146	None	0.7639	0.7798	None	D	-0.03	None	None	-0.131	None	None	None	None	None	None	None	1.0	None	None	0.384	0.731	None	None	None	1.99681E-04	0	0	None	0	1E-03	None	None	1.99681E-04	None	0	None	None	I	None
21238	62	R/C	rs190432620	0.7666	gnomAD-4.0.0	146	None	0.7639	0.7798	None	D	-0.03	None	None	-0.131	None	None	None	None	None	None	None	1.0	None	None	0.384	0.731	None	None	None	1.11632E-05	1.33461E-05	0	0	2.24376E-05	None	0	0	1.11632E-05	1.01755E-05	4.39454E-05	0	None	I	None
21238	62	R/H	rs544396866	0.7666	gnomAD-2.1.1	146	None	0.5617	0.6035	32.0	N	-0.612	0.9	0.027236	-0.701	0.3602	-0.2491	0.515550123524	2.945	1.0	0.498	0.398581233421	1.0	0.714249491692	-4.0	0.409	0.757	None	None	None	1.79E-05	0	0	0	0	None	1.3101E-04	None	1.79E-05	0	0	1.41363E-04	None	I	None
21238	62	R/H	rs544396866	0.7666	gnomAD-3.1.2	146	None	0.5617	0.6035	32.0	N	-0.612	0.9	0.027236	-0.701	0.3602	-0.2491	0.515550123524	2.945	1.0	0.498	0.398581233421	1.0	0.714249491692	-4.0	0.409	0.757	None	None	None	2.63E-05	2.42E-05	0	0	0	None	0	0	2.63E-05	0	6.20861E-04	0	None	I	None
21238	62	R/H	rs544396866	0.7666	1000 genomes	146	None	0.5617	0.6035	32.0	N	-0.612	0.9	0.027236	-0.701	0.3602	-0.2491	0.515550123524	2.945	1.0	0.498	0.398581233421	1.0	0.714249491692	-4.0	0.409	0.757	None	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	I	None
21238	62	R/H	rs544396866	0.7666	gnomAD-4.0.0	146	None	0.5617	0.6035	32.0	N	-0.612	0.9	0.027236	-0.701	0.3602	-0.2491	0.515550123524	2.945	1.0	0.498	0.398581233421	1.0	0.714249491692	-4.0	0.409	0.757	None	None	None	1.17827E-05	1.33415E-05	0	0	0	None	0	0	1.17827E-05	5.08767E-06	1.31842E-04	0	None	I	None
21238	62	R/L	rs544396866	0.7666	gnomAD-2.1.1	146	None	0.9092	0.9029	32.0	N	0.466	1.05	0.031471	0.404	0.2954	-0.5331	0.516030974754	2.15	1.0	0.485	0.283761946502	1.0	0.710906684399	-5.6	0.433	0.605	None	None	None	4.04E-06	0	0	0	0	None	3.28E-05	None	4.04E-06	0	0	0	None	I	None
21238	62	R/L	rs544396866	0.7666	gnomAD-4.0.0	146	None	0.9092	0.9029	32.0	N	0.466	1.05	0.031471	0.404	0.2954	-0.5331	0.516030974754	2.15	1.0	0.485	0.283761946502	1.0	0.710906684399	-5.6	0.433	0.605	None	None	None	6.84728E-07	0	0	0	0	None	0	0	6.84728E-07	0	1.16023E-05	0	None	I	None
21239	63	D/E	None	0.6095	gnomAD-4.0.0	148	None	0.1108	0.1265	23.7	N	None	1.16	0.009425	-0.167	0.0438	-1.0848	0.120133638722	0.255	0.99977	0.515	0.204665344411	0.619	0.66981613636	-2.3	0.069	0.268	0.298	None	None	1.59406E-06	0	0	0	0	None	0	0	1.59406E-06	2.86148E-06	0	0	None	I	None
21240	64	D/N	rs1031557327	0.1788	gnomAD-3.1.2	149	None	0.8479	0.8771	26.7	D	None	-1.44	0.036971	-0.685	0.7978	0.7903	0.459178880736	3.595	1.0	0.815	0.686399706189	1.0	0.698646664619	-3.9	0.707	0.774	0.004	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
21240	64	D/N	rs1031557327	0.1788	gnomAD-4.0.0	149	None	0.8479	0.8771	26.7	D	None	-1.44	0.036971	-0.685	0.7978	0.7903	0.459178880736	3.595	1.0	0.815	0.686399706189	1.0	0.698646664619	-3.9	0.707	0.774	0.004	None	None	2.56637E-06	0	0	0	0	None	0	0	2.56637E-06	4.79136E-06	0	0	None	N	None
21246	70	L/F	rs2049306666	0.1238	gnomAD-3.1.2	156	None	0.6834	0.6957	27.0	N	None	0.94	0.018006	-1.3	0.281	-0.5107	0.482416341566	2.78	0.99997	0.648	0.562428738172	1.0	0.714169025421	-3.13	0.375	0.859	0.006	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
21246	70	L/F	rs2049306666	0.1238	gnomAD-4.0.0	156	None	0.6834	0.6957	27.0	N	None	0.94	0.018006	-1.3	0.281	-0.5107	0.482416341566	2.78	0.99997	0.648	0.562428738172	1.0	0.714169025421	-3.13	0.375	0.859	0.006	None	None	6.57903E-06	0	6.55652E-05	0	0	None	0	0	6.57903E-06	0	0	0	None	N	None
21246	70	L/V	None	0.1238	gnomAD-4.0.0	156	None	0.2221	0.2533	23.0	N	None	1.05	0.011768	-1.165	0.1679	-0.879	0.465770963553	0.77	0.999144	0.552	0.418964662724	0.999	0.68458122015	-2.33	0.193	0.713	0.006	None	None	1.59435E-06	0	0	0	0	None	0	0	1.59435E-06	2.86208E-06	0	0	None	N	None
21247	71	T/A	None	0.1565	gnomAD-4.0.0	157	None	0.1461	0.161	24.6	N	None	-0.29	0.019159	-1.068	0.2987	-0.3171	0.148960912717	2.755	0.953353	0.369	0.374613414588	0.489	0.644097328186	-3.7	0.297	0.621	0.012	None	None	1.59453E-06	0	0	0	0	None	0	0	1.59453E-06	2.86226E-06	0	0	None	N	None
21248	72	L/F	rs771468174	0.2017	gnomAD-2.1.1	158	None	0.8468	0.8558	24.2	D	-1.592	-0.27	0.026458	-1.455	0.5545	0.3235	0.435919991296	3.39	0.999812	0.59	0.732364685296	0.978	0.609217822552	-2.87	0.453	0.833	0.011	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	4.69E-05	0	0	None	N	None
21248	72	L/F	rs771468174	0.2017	gnomAD-4.0.0	158	None	0.8468	0.8558	24.2	D	-1.592	-0.27	0.026458	-1.455	0.5545	0.3235	0.435919991296	3.39	0.999812	0.59	0.732364685296	0.978	0.609217822552	-2.87	0.453	0.833	0.011	None	None	6.16354E-06	0	0	0	0	None	1.87913E-05	0	6.16354E-06	6.29937E-06	0	1.65881E-05	None	N	None
21248	72	L/P	rs745323281	0.2017	gnomAD-2.1.1	158	None	0.9902	0.9934	28.8	N	-1.839	-0.28	0.047261	-1.434	0.5266	0.1608	0.566887195539	3.39	1.0	0.663	0.85706450173	0.996	0.719642519951	-4.87	0.657	0.867	0.005	None	None	3.24E-05	0	8.54E-05	0	0	None	0	None	3.24E-05	0	4.72E-05	0	None	N	None
21248	72	L/P	rs745323281	0.2017	gnomAD-3.1.2	158	None	0.9902	0.9934	28.8	N	-1.839	-0.28	0.047261	-1.434	0.5266	0.1608	0.566887195539	3.39	1.0	0.663	0.85706450173	0.996	0.719642519951	-4.87	0.657	0.867	0.005	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	N	None
21248	72	L/P	rs745323281	0.2017	gnomAD-4.0.0	158	None	0.9902	0.9934	28.8	N	-1.839	-0.28	0.047261	-1.434	0.5266	0.1608	0.566887195539	3.39	1.0	0.663	0.85706450173	0.996	0.719642519951	-4.87	0.657	0.867	0.005	None	None	2.10913E-05	0	5.01387E-05	0	0	None	0	0	2.10913E-05	2.62908E-05	0	0	None	N	None
21249	73	V/L	None	0.3494	gnomAD-4.0.0	159	None	0.1752	0.179	22.7	N	None	-0.18	0.043588	-0.735	0.2284	-0.635	0.194339757416	1.375	0.978244	0.433	0.52540932818	0.826	0.619421124458	-1.73	0.178	0.443	0.183	None	None	1.36984E-06	0	0	0	0	None	0	0	1.36984E-06	1.79996E-06	0	0	None	I	None
21249	73	V/M	None	0.3494	gnomAD-4.0.0	159	None	0.1511	0.1502	24.3	N	None	-0.27	0.038095	-0.488	0.3819	-0.2782	0.428286057823	1.575	0.981379	0.425	0.610882576163	0.996	0.650241434574	-1.43	0.275	0.475	0.065	None	None	3.4246E-06	0	0	0	0	None	0	0	3.4246E-06	4.49989E-06	0	0	None	I	None
21250	74	N/K	rs773738001	0.1875	gnomAD-2.1.1	161	None	0.9969	0.997	24.8	D	-0.404	0.25	0.05084	-0.327	0.5321	0.1104	0.496214373149	4.13	0.996244	0.856	0.336155897331	1.0	0.767543375492	-4.47	0.541	0.717	0.004	None	None	8.11E-06	0	0	0	1.13289E-04	None	0	None	8.11E-06	0	0	0	None	I	None
21250	74	N/K	rs773738001	0.1875	gnomAD-4.0.0	161	None	0.9969	0.997	24.8	D	-0.404	0.25	0.05084	-0.327	0.5321	0.1104	0.496214373149	4.13	0.996244	0.856	0.336155897331	1.0	0.767543375492	-4.47	0.541	0.717	0.004	None	None	3.19096E-06	0	0	0	5.58534E-05	None	0	0	3.19096E-06	0	0	0	None	I	None
21251	75	P/A	None	0.6938	gnomAD-4.0.0	162	None	0.0756	0.0757	23.7	N	None	-0.19	0.009341	-0.288	0.119	-0.9896	0.0816010712385	0.365	0.982612	0.439	0.195762928549	0.001	0.435894191265	-4.77	0.146	0.134	0.22	None	None	6.85253E-07	0	0	0	0	None	0	0	6.85253E-07	9.00383E-07	0	0	None	I	None
21251	75	P/S	None	0.6938	gnomAD-4.0.0	162	None	0.1191	0.1157	24.1	N	None	-0.02	0.007779	-0.37	0.0998	-1.0284	0.0868971396711	0.07	0.989247	0.415	0.165133752707	0.003	0.41088655591	-5.1	0.129	0.133	0.168	None	None	4.11152E-06	0	0	0	0	None	0	0	4.11152E-06	5.4023E-06	0	0	None	I	None
21251	75	P/T	None	0.6938	gnomAD-4.0.0	162	None	0.1009	0.0975	23.9	N	None	-0.21	0.013537	-0.404	0.169	-0.8934	0.0948894062575	1.0	0.989051	0.418	0.243398259712	0.002	0.430987000465	-5.17	0.18	0.172	0.013	None	None	6.85253E-07	0	0	0	0	None	0	0	6.85253E-07	9.00383E-07	0	0	None	I	None
21252	76	A/P	rs1414305945	0.6679	gnomAD-2.1.1	163	None	0.8804	0.8702	24.9	D	-0.189	-0.42	0.035866	-0.353	0.5916	0.2869	0.511076341954	3.28	1.0	0.67	0.464442853059	0.999	0.696692228317	-3.53	0.514	0.701	0.01	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.48E-05	0	None	I	None
21252	76	A/P	rs1414305945	0.6679	gnomAD-3.1.2	163	None	0.8804	0.8702	24.9	D	-0.189	-0.42	0.035866	-0.353	0.5916	0.2869	0.511076341954	3.28	1.0	0.67	0.464442853059	0.999	0.696692228317	-3.53	0.514	0.701	0.01	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
21252	76	A/P	rs1414305945	0.6679	gnomAD-4.0.0	163	None	0.8804	0.8702	24.9	D	-0.189	-0.42	0.035866	-0.353	0.5916	0.2869	0.511076341954	3.28	1.0	0.67	0.464442853059	0.999	0.696692228317	-3.53	0.514	0.701	0.01	None	None	6.58085E-06	0	0	0	0	None	0	0	6.58085E-06	1.47098E-05	0	0	None	I	None
21253	77	G/V	rs770861395	0.3582	gnomAD-2.1.1	164	None	0.8798	0.8974	27.7	D	-0.023	-0.9	0.041884	-0.397	0.7622	0.7778	0.518063289252	4.175	1.0	0.87	0.759615262451	1.0	0.806829571724	-7.2	0.739	0.872	0.003	None	None	3.19E-05	1.14863E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	I	None
21253	77	G/V	rs770861395	0.3582	gnomAD-3.1.2	164	None	0.8798	0.8974	27.7	D	-0.023	-0.9	0.041884	-0.397	0.7622	0.7778	0.518063289252	4.175	1.0	0.87	0.759615262451	1.0	0.806829571724	-7.2	0.739	0.872	0.003	None	None	6.58E-06	2.42E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
21253	77	G/V	rs770861395	0.3582	gnomAD-4.0.0	164	None	0.8798	0.8974	27.7	D	-0.023	-0.9	0.041884	-0.397	0.7622	0.7778	0.518063289252	4.175	1.0	0.87	0.759615262451	1.0	0.806829571724	-7.2	0.739	0.872	0.003	None	None	6.58033E-06	2.41523E-05	0	0	0	None	0	0	6.58033E-06	0	0	0	None	I	None
21254	78	E/K	None	0.5947	gnomAD-4.0.0	165	None	0.282	0.2501	32.0	N	None	-0.2	0.035156	0.508	0.2474	-0.5399	0.338184895751	1.18	1.0	0.611	0.309530620856	0.955	0.769835829735	-2.93	0.345	0.603	0.126	None	None	1.20034E-06	0	0	0	0	None	0	0	1.20034E-06	0	6.07533E-05	0	None	I	None
21256	80	A/T	rs1277491841	0.3047	gnomAD-2.1.1	168	None	0.167	0.1909	27.8	N	-0.638	-0.05	0.033669	-0.8	0.2445	-0.3524	0.457598942377	0.365	1.0	0.401	0.500176316166	1.0	0.749635398388	-2.93	0.388	0.702	0.197	None	None	4.08E-06	0	2.94E-05	0	0	None	0	None	4.08E-06	0	0	0	None	I	None
21256	80	A/T	rs1277491841	0.3047	gnomAD-4.0.0	168	None	0.167	0.1909	27.8	N	-0.638	-0.05	0.033669	-0.8	0.2445	-0.3524	0.457598942377	0.365	1.0	0.401	0.500176316166	1.0	0.749635398388	-2.93	0.388	0.702	0.197	None	None	1.6E-06	0	2.30563E-05	0	0	None	0	0	1.6E-06	0	0	0	None	I	None
21259	83	V/I	rs371286595	0.1950	gnomAD-2.1.1	172	None	0.1081	0.114	None	N	-0.073	None	None	-0.341	None	None	None	None	None	None	None	0.999	None	None	0.299	0.626	None	None	None	8.34E-05	4.17537E-04	0	0	0	None	3.34E-05	None	8.34E-05	8.09E-05	7.93E-05	0	None	N	None
21259	83	V/I	rs371286595	0.1950	gnomAD-3.1.2	172	None	0.1081	0.114	None	N	-0.073	None	None	-0.341	None	None	None	None	None	None	None	0.999	None	None	0.299	0.626	None	None	None	1.11866E-04	4.10787E-04	0	0	0	None	0	0	1.11866E-04	0	0	0	None	N	None
21259	83	V/I	rs371286595	0.1950	gnomAD-4.0.0	172	None	0.1081	0.114	None	N	-0.073	None	None	-0.341	None	None	None	None	None	None	None	0.999	None	None	0.299	0.626	None	None	None	3.17018E-05	2.94645E-04	0	0	0	None	3.13706E-05	0	3.17018E-05	1.86892E-05	4.41852E-05	1.60705E-05	None	N	None
21261	85	V/I	None	0.1277	gnomAD-4.0.0	174	None	0.1675	0.1764	29.6	N	None	0.84	0.017392	-0.649	0.3716	-0.2808	0.420894402933	2.29	1.0	0.446	0.555788435936	0.997	0.59900277853	-0.8	0.321	0.551	None	None	None	3.20566E-06	0	0	0	0	None	0	0	3.20566E-06	0	2.88667E-05	0	None	I	None
21262	86	R/G	None	0.6088	gnomAD-4.0.0	175	None	0.5887	0.6786	27.2	N	None	-0.25	0.057789	-0.913	0.3187	-0.3933	0.141454853082	2.99	0.966354	0.553	0.43923137753	0.117	0.582635223866	-4.22	0.307	0.473	0.003	None	None	1.60277E-06	0	0	0	0	None	0	0	1.60277E-06	2.87829E-06	0	0	None	I	None
21262	86	R/T	rs1342165359	0.6088	gnomAD-2.1.1	175	None	0.3443	0.4143	24.3	N	-0.254	-0.1	0.03731	-0.609	0.215	-0.6142	0.174460457525	0.71	0.929898	0.545	0.331365685468	0.117	0.627061784267	-3.42	0.145	0.448	0.004	None	None	4.09E-06	0	2.95E-05	0	0	None	0	None	4.09E-06	0	0	0	None	I	None
21262	86	R/T	rs1342165359	0.6088	gnomAD-4.0.0	175	None	0.3443	0.4143	24.3	N	-0.254	-0.1	0.03731	-0.609	0.215	-0.6142	0.174460457525	0.71	0.929898	0.545	0.331365685468	0.117	0.627061784267	-3.42	0.145	0.448	0.004	None	None	1.60321E-06	0	2.31471E-05	0	0	None	0	0	1.60321E-06	0	0	0	None	I	None
21263	87	V/G	None	0.1465	gnomAD-4.0.0	177	None	0.9712	0.9731	32.0	D	None	-1.26	0.092394	-2.151	0.7786	0.8655	0.527292994097	4.295	1.0	0.722	0.93082256464	1.0	0.674307584763	-5.6	0.825	0.815	None	None	None	1.60281E-06	0	0	0	0	None	0	0	1.60281E-06	2.87806E-06	0	0	None	N	None
21263	87	V/I	rs1298535121	0.1465	gnomAD-2.1.1	177	None	0.1797	0.1949	29.5	D	-0.75	-0.82	0.018508	-0.979	0.6561	0.3781	0.420894402933	2.75	1.0	0.701	0.79560923071	0.997	0.642305374146	-0.8	0.539	0.733	None	None	None	4.09E-06	0	0	0	0	None	0	None	4.09E-06	0	9.03E-06	0	None	N	None
21263	87	V/I	rs1298535121	0.1465	gnomAD-4.0.0	177	None	0.1797	0.1949	29.5	D	-0.75	-0.82	0.018508	-0.979	0.6561	0.3781	0.420894402933	2.75	1.0	0.701	0.79560923071	0.997	0.642305374146	-0.8	0.539	0.733	None	None	None	3.20539E-06	0	0	0	0	None	0	0	3.20539E-06	2.87776E-06	1.44292E-05	0	None	N	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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