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The data displayed in the table aims to be as complete as possible and contains information for all available sources including different versions of the same source, for example, different sources of gnomAD. To avoid seeing multiple entries for the same variant, we recommend to sort by Source first.
Pin SAV |
Position |
Domain position |
SAV |
Structural Position |
RS |
Q(SASA) |
Disease |
Source |
MAF |
---|---|---|---|---|---|---|---|---|---|
2174 | 1 | I/M | 1 | rs1414401674 | 0.3919 | None | gnomAD-2.1.1 | 7.98E-06 | |
2174 | 1 | I/M | 1 | rs1414401674 | 0.3919 | None | gnomAD-4.0.0 | 1.36834E-06 | |
2174 | 1 | I/V | 1 | rs1171508892 | 0.3919 | None | gnomAD-2.1.1 | 3.99E-06 | |
2174 | 1 | I/V | 1 | rs1171508892 | 0.3919 | None | gnomAD-4.0.0 | 3.18193E-06 | |
2176 | 3 | F/L | 3 | rs1423674252 | 0.1840 | None | gnomAD-2.1.1 | 7.09E-06 | |
2176 | 3 | F/L | 3 | rs1423674252 | 0.1840 | None | gnomAD-3.1.2 | 1.31E-05 | |
2176 | 3 | F/L | 3 | rs1423674252 | 0.1840 | None | gnomAD-4.0.0 | 5.12319E-06 | |
2177 | 4 | T/I | 4 | None | 0.4248 | None | gnomAD-4.0.0 | 2.05244E-06 | |
2178 | 5 | Q/R | 5 | None | 0.3608 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2179 | 6 | E/V | 7 | None | 0.6889 | None | gnomAD-4.0.0 | 1.59088E-06 | |
2182 | 9 | D/V | 11 | None | 0.5000 | None | gnomAD-4.0.0 | 1.59085E-06 | |
2183 | 10 | V/I | 13 | rs940814498 | 0.1920 | None | gnomAD-2.1.1 | 1.06E-05 | |
2183 | 10 | V/I | 13 | rs940814498 | 0.1920 | None | gnomAD-3.1.2 | 3.94E-05 | |
2183 | 10 | V/I | 13 | rs940814498 | 0.1920 | None | gnomAD-4.0.0 | 8.67516E-06 | |
2184 | 11 | V/A | 14 | None | 0.4808 | None | gnomAD-4.0.0 | 1.59088E-06 | |
2185 | 12 | A/P | 16 | rs367653049 | 0.1641 | None | gnomAD-3.1.2 | 6.57E-06 | |
2185 | 12 | A/P | 16 | rs367653049 | 0.1641 | None | gnomAD-4.0.0 | 6.57462E-06 | |
2189 | 16 | D/Y | 25 | rs1252868552 | 0.3517 | None | gnomAD-4.0.0 | 1.20033E-06 | |
2190 | 17 | T/A | 26 | rs1204873968 | 0.8064 | None | gnomAD-2.1.1 | 3.99E-06 | |
2190 | 17 | T/A | 26 | rs1204873968 | 0.8064 | None | gnomAD-3.1.2 | 6.57E-06 | |
2190 | 17 | T/A | 26 | rs1204873968 | 0.8064 | None | gnomAD-4.0.0 | 2.47841E-06 | |
2190 | 17 | T/I | 26 | rs767577772 | 0.8064 | None | gnomAD-2.1.1 | 1.2E-05 | |
2190 | 17 | T/I | 26 | rs767577772 | 0.8064 | None | gnomAD-3.1.2 | 6.57E-06 | |
2190 | 17 | T/I | 26 | rs767577772 | 0.8064 | None | gnomAD-4.0.0 | 3.84227E-06 | |
2191 | 18 | M/V | 27 | rs760003993 | 0.4198 | None | gnomAD-2.1.1 | 1.2E-05 | |
2191 | 18 | M/V | 27 | rs760003993 | 0.4198 | None | gnomAD-3.1.2 | 1.31E-05 | |
2191 | 18 | M/V | 27 | rs760003993 | 0.4198 | None | gnomAD-4.0.0 | 4.33728E-06 | |
2192 | 19 | A/E | 28 | None | 0.1769 | None | gnomAD-4.0.0 | 1.20033E-06 | |
2192 | 19 | A/T | 28 | rs774574739 | 0.1769 | None | gnomAD-2.1.1 | 2.79E-05 | |
2192 | 19 | A/T | 28 | rs774574739 | 0.1769 | None | gnomAD-3.1.2 | 9.21E-05 | |
2192 | 19 | A/T | 28 | rs774574739 | 0.1769 | None | gnomAD-4.0.0 | 2.43371E-05 | |
2193 | 20 | T/A | 29 | rs147148170 | 0.2989 | None | gnomAD-2.1.1 | 3.99E-06 | |
2193 | 20 | T/A | 29 | rs147148170 | 0.2989 | None | gnomAD-3.1.2 | 6.57E-06 | |
2193 | 20 | T/A | 29 | rs147148170 | 0.2989 | None | gnomAD-4.0.0 | 6.57082E-06 | |
2193 | 20 | T/I | 29 | None | 0.2989 | None | gnomAD-4.0.0 | 1.36826E-06 | |
2193 | 20 | T/N | 29 | rs1574640739 | 0.2989 | None | gnomAD-4.0.0 | 2.05239E-06 | |
2195 | 22 | E/G | 31 | rs202032875 | 0.3324 | None | gnomAD-2.1.1 | 1.94897E-04 | |
2195 | 22 | E/G | 31 | rs202032875 | 0.3324 | None | gnomAD-3.1.2 | 2.10286E-04 | |
2195 | 22 | E/G | 31 | rs202032875 | 0.3324 | None | gnomAD-4.0.0 | 2.67052E-04 | |
2196 | 23 | C/R | 33 | None | 0.0762 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2196 | 23 | C/S | 33 | None | 0.0762 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2196 | 23 | C/Y | 33 | rs878854326 | 0.0762 | None | gnomAD-2.1.1 | 7.09E-06 | |
2196 | 23 | C/Y | 33 | rs878854326 | 0.0762 | None | gnomAD-3.1.2 | 1.31E-05 | |
2196 | 23 | C/Y | 33 | rs878854326 | 0.0762 | None | gnomAD-4.0.0 | 6.40379E-06 | |
2197 | 24 | E/K | 34 | rs139329751 | 0.1920 | None | gnomAD-2.1.1 | 3.99E-06 | |
2197 | 24 | E/K | 34 | rs139329751 | 0.1920 | None | gnomAD-4.0.0 | 3.18157E-06 | |
2198 | 25 | T/A | 35 | None | 0.0952 | None | gnomAD-4.0.0 | 1.36823E-06 | |
2198 | 25 | T/I | 35 | rs886038879 | 0.0952 | None | gnomAD-2.1.1 | 3.19E-05 | |
2198 | 25 | T/I | 35 | rs886038879 | 0.0952 | None | gnomAD-3.1.2 | 6.57E-06 | |
2198 | 25 | T/I | 35 | rs886038879 | 0.0952 | None | gnomAD-4.0.0 | 2.56157E-06 | |
2198 | 25 | T/S | 35 | None | 0.0952 | None | gnomAD-4.0.0 | 6.84115E-07 | |
2200 | 27 | E/K | 41 | rs1378587847 | 0.3546 | None | gnomAD-2.1.1 | 3.99E-06 | |
2200 | 27 | E/K | 41 | rs1378587847 | 0.3546 | None | gnomAD-4.0.0 | 6.84119E-06 | |
2201 | 28 | P/S | 42 | rs763426070 | 0.2892 | None | gnomAD-2.1.1 | 7.97E-06 | |
2202 | 29 | F/L | 43 | None | 0.6595 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2202 | 29 | F/S | 43 | rs773658956 | 0.6595 | None | gnomAD-2.1.1 | 3.99E-06 | |
2202 | 29 | F/S | 43 | rs773658956 | 0.6595 | None | gnomAD-4.0.0 | 7.20193E-06 | |
2203 | 30 | V/A | 44 | rs746433556 | 0.2354 | None | gnomAD-2.1.1 | 7.97E-06 | |
2203 | 30 | V/A | 44 | rs746433556 | 0.2354 | None | gnomAD-3.1.2 | 5.26E-05 | |
2203 | 30 | V/A | 44 | rs746433556 | 0.2354 | None | gnomAD-4.0.0 | 9.91375E-06 | |
2203 | 30 | V/F | 44 | rs768181882 | 0.2354 | None | gnomAD-2.1.1 | 3.99E-06 | |
2203 | 30 | V/F | 44 | rs768181882 | 0.2354 | None | gnomAD-4.0.0 | 2.73647E-06 | |
2203 | 30 | V/I | 44 | rs768181882 | 0.2354 | None | gnomAD-2.1.1 | 3.99E-06 | |
2203 | 30 | V/I | 44 | rs768181882 | 0.2354 | None | gnomAD-3.1.2 | 6.57E-06 | |
2203 | 30 | V/I | 44 | rs768181882 | 0.2354 | None | gnomAD-4.0.0 | 6.57099E-06 | |
2204 | 31 | K/E | 45 | rs1466089767 | 0.8024 | None | gnomAD-4.0.0 | 2.05233E-06 | |
2204 | 31 | K/N | 45 | rs1060500448 | 0.8024 | None | gnomAD-2.1.1 | 3.98E-06 | |
2204 | 31 | K/N | 45 | rs1060500448 | 0.8024 | None | gnomAD-3.1.2 | 6.57E-06 | |
2204 | 31 | K/N | 45 | rs1060500448 | 0.8024 | None | gnomAD-4.0.0 | 7.68421E-06 | |
2205 | 32 | V/M | 46 | rs2154345518 | 0.2163 | None | gnomAD-3.1.2 | 6.57E-06 | |
2205 | 32 | V/M | 46 | rs2154345518 | 0.2163 | None | gnomAD-4.0.0 | 6.56556E-06 | |
2206 | 33 | K/R | 47 | None | 0.3209 | None | gnomAD-4.0.0 | 1.59074E-06 | |
2208 | 35 | Y/C | 49 | rs1186847832 | 0.2042 | None | gnomAD-3.1.2 | 6.57E-06 | |
2208 | 35 | Y/C | 49 | rs1186847832 | 0.2042 | None | gnomAD-4.0.0 | 5.07445E-06 | |
2209 | 36 | K/Q | 50 | rs1260981476 | 0.1446 | None | gnomAD-4.0.0 | 1.59075E-06 | |
2210 | 37 | D/N | 51 | rs2154345509 | 0.8441 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2211 | 38 | G/S | 52 | rs779819023 | 0.3993 | None | gnomAD-2.1.1 | 7.97E-06 | |
2211 | 38 | G/S | 52 | rs779819023 | 0.3993 | None | gnomAD-4.0.0 | 3.18155E-06 | |
2211 | 38 | G/V | 52 | None | 0.3993 | None | gnomAD-4.0.0 | 1.59077E-06 | |
2212 | 39 | M/T | 55 | rs2092055359 | 0.7226 | None | gnomAD-3.1.2 | 6.57E-06 | |
2212 | 39 | M/T | 55 | rs2092055359 | 0.7226 | None | gnomAD-4.0.0 | 6.57039E-06 | |
2212 | 39 | M/V | 55 | rs771623139 | 0.7226 | None | gnomAD-2.1.1 | 1.19E-05 | |
2212 | 39 | M/V | 55 | rs771623139 | 0.7226 | None | gnomAD-4.0.0 | 7.95391E-06 | |
2213 | 40 | E/D | 56 | rs745719077 | 0.2944 | None | gnomAD-2.1.1 | 1.42E-05 | |
2213 | 40 | E/D | 56 | rs745719077 | 0.2944 | None | gnomAD-3.1.2 | 1.97E-05 | |
2213 | 40 | E/D | 56 | rs745719077 | 0.2944 | None | gnomAD-4.0.0 | 1.85881E-06 | |
2214 | 41 | V/I | 58 | rs2092054706 | 0.1468 | None | gnomAD-4.0.0 | 1.59077E-06 | |
2215 | 42 | H/R | 59 | rs778552915 | 0.7500 | None | gnomAD-2.1.1 | 3.98E-06 | |
2215 | 42 | H/R | 59 | rs778552915 | 0.7500 | None | gnomAD-4.0.0 | 1.59074E-06 | |
2216 | 43 | E/D | 70 | None | 0.5924 | None | gnomAD-4.0.0 | 1.59077E-06 | |
2217 | 44 | G/A | 73 | rs146236689 | 0.3565 | None | gnomAD-2.1.1 | 3.98E-06 | |
2217 | 44 | G/A | 73 | rs146236689 | 0.3565 | None | gnomAD-4.0.0 | 2.05236E-06 | |
2217 | 44 | G/R | 73 | None | 0.3565 | None | gnomAD-4.0.0 | 2.05236E-06 | |
2218 | 45 | D/G | 111 | None | 1.1755 | None | gnomAD-4.0.0 | 2.40064E-06 | |
2219 | 46 | K/Q | 115 | rs1292302676 | 0.1823 | None | gnomAD-2.1.1 | 3.19E-05 | |
2219 | 46 | K/Q | 115 | rs1292302676 | 0.1823 | None | gnomAD-3.1.2 | 6.57E-06 | |
2219 | 46 | K/Q | 115 | rs1292302676 | 0.1823 | None | gnomAD-4.0.0 | 3.84199E-06 | |
2219 | 46 | K/R | 115 | rs1482793298 | 0.1823 | None | gnomAD-2.1.1 | 3.98E-06 | |
2219 | 46 | K/R | 115 | rs1482793298 | 0.1823 | None | gnomAD-4.0.0 | 1.59078E-06 | |
2220 | 47 | Y/C | 121 | None | 0.2288 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2220 | 47 | Y/H | 121 | rs1235706679 | 0.2288 | None | gnomAD-2.1.1 | 3.98E-06 | |
2220 | 47 | Y/H | 121 | rs1235706679 | 0.2288 | None | gnomAD-4.0.0 | 4.10473E-06 | |
2221 | 48 | R/K | 122 | None | 0.7102 | None | gnomAD-4.0.0 | 1.5908E-06 | |
2222 | 49 | M/K | 123 | None | 0.2555 | None | gnomAD-4.0.0 | 6.84119E-07 | |
2222 | 49 | M/T | 123 | rs757071471 | 0.2555 | None | gnomAD-2.1.1 | 1.59E-05 | |
2222 | 49 | M/T | 123 | rs757071471 | 0.2555 | None | gnomAD-4.0.0 | 2.73648E-06 | |
2222 | 49 | M/V | 123 | rs1212976670 | 0.2555 | None | gnomAD-2.1.1 | 3.98E-06 | |
2222 | 49 | M/V | 123 | rs1212976670 | 0.2555 | None | gnomAD-4.0.0 | 1.59079E-06 | |
2223 | 50 | H/L | 125 | rs372979075 | 0.4203 | None | gnomAD-2.1.1 | 6.72E-05 | |
2223 | 50 | H/L | 125 | rs372979075 | 0.4203 | None | gnomAD-3.1.2 | 5.26E-05 | |
2223 | 50 | H/L | 125 | rs372979075 | 0.4203 | None | 1000 genomes | 3.99361E-04 | |
2223 | 50 | H/L | 125 | rs372979075 | 0.4203 | None | gnomAD-4.0.0 | 2.35436E-05 | |
2223 | 50 | H/Q | 125 | rs1237315602 | 0.4203 | None | gnomAD-2.1.1 | 3.98E-06 | |
2223 | 50 | H/Q | 125 | rs1237315602 | 0.4203 | None | gnomAD-4.0.0 | 1.59082E-06 | |
2223 | 50 | H/R | 125 | None | 0.4203 | None | gnomAD-4.0.0 | 6.84121E-07 | |
2224 | 51 | S/C | 127 | None | 0.3962 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2225 | 52 | D/N | 130 | None | 0.6957 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2226 | 53 | R/K | 131 | rs370438618 | 0.6502 | None | gnomAD-2.1.1 | 1.19E-05 | |
2226 | 53 | R/K | 131 | rs370438618 | 0.6502 | None | gnomAD-3.1.2 | 6.57E-06 | |
2226 | 53 | R/K | 131 | rs370438618 | 0.6502 | None | gnomAD-4.0.0 | 7.43544E-06 | |
2228 | 55 | V/A | 135 | rs752706070 | 0.1833 | None | gnomAD-2.1.1 | 7.96E-06 | |
2228 | 55 | V/A | 135 | rs752706070 | 0.1833 | None | gnomAD-3.1.2 | 1.31E-05 | |
2228 | 55 | V/A | 135 | rs752706070 | 0.1833 | None | gnomAD-4.0.0 | 4.95711E-06 | |
2228 | 55 | V/F | 135 | None | 0.1833 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2228 | 55 | V/G | 135 | None | 0.1833 | None | gnomAD-4.0.0 | 6.84139E-07 | |
2228 | 55 | V/I | 135 | None | 0.1833 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2229 | 56 | H/Y | 136 | rs56851316 | 0.1302 | None | gnomAD-2.1.1 | 3.98E-06 | |
2229 | 56 | H/Y | 136 | rs56851316 | 0.1302 | None | gnomAD-3.1.2 | 6.57E-06 | |
2229 | 56 | H/Y | 136 | rs56851316 | 0.1302 | None | 1000 genomes | 1.99681E-04 | |
2229 | 56 | H/Y | 136 | rs56851316 | 0.1302 | None | gnomAD-4.0.0 | 2.56119E-06 | |
2230 | 57 | F/C | 137 | None | 0.1742 | None | gnomAD-4.0.0 | 6.84128E-07 | |
2231 | 58 | L/F | 138 | None | 0.0782 | None | gnomAD-4.0.0 | 1.59083E-06 | |
2232 | 59 | S/F | 139 | rs377098846 | 0.1506 | None | gnomAD-2.1.1 | 3.98E-06 | |
2233 | 60 | I/T | 140 | rs1364650008 | 0.0871 | None | gnomAD-2.1.1 | 7.96E-06 | |
2233 | 60 | I/T | 140 | rs1364650008 | 0.0871 | None | gnomAD-4.0.0 | 4.7726E-06 | |
2233 | 60 | I/V | 140 | rs1574638831 | 0.0871 | None | gnomAD-4.0.0 | 2.05239E-06 | |
2234 | 61 | L/M | 141 | rs766750289 | 0.2921 | None | gnomAD-2.1.1 | 1.59E-05 | |
2234 | 61 | L/M | 141 | rs766750289 | 0.2921 | None | gnomAD-3.1.2 | 1.31E-05 | |
2234 | 61 | L/M | 141 | rs766750289 | 0.2921 | None | gnomAD-4.0.0 | 4.33727E-06 | |
2234 | 61 | L/P | 141 | rs534604830 | 0.2921 | None | gnomAD-2.1.1 | 7.96E-06 | |
2234 | 61 | L/P | 141 | rs534604830 | 0.2921 | None | gnomAD-3.1.2 | 6.57E-06 | |
2234 | 61 | L/P | 141 | rs534604830 | 0.2921 | None | 1000 genomes | 1.99681E-04 | |
2234 | 61 | L/P | 141 | rs534604830 | 0.2921 | None | gnomAD-4.0.0 | 2.56096E-06 | |
2234 | 61 | L/Q | 141 | None | 0.2921 | None | gnomAD-4.0.0 | 1.59084E-06 | |
2235 | 62 | T/I | 143 | rs1381061706 | 0.6342 | None | gnomAD-4.0.0 | 6.8413E-07 | |
2235 | 62 | T/S | 143 | None | 0.6342 | None | gnomAD-4.0.0 | 6.8413E-07 | |
2236 | 63 | I/F | 144 | rs1328042181 | 0.1149 | None | gnomAD-2.1.1 | 3.18E-05 | |
2236 | 63 | I/F | 144 | rs1328042181 | 0.1149 | None | gnomAD-3.1.2 | 6.57E-06 | |
2236 | 63 | I/F | 144 | rs1328042181 | 0.1149 | None | gnomAD-4.0.0 | 6.57237E-06 | |
2236 | 63 | I/S | 144 | None | 0.1149 | None | gnomAD-4.0.0 | 6.84131E-07 | |
2236 | 63 | I/T | 144 | rs1189735228 | 0.1149 | None | gnomAD-2.1.1 | 7.96E-06 | |
2236 | 63 | I/T | 144 | rs1189735228 | 0.1149 | None | gnomAD-4.0.0 | 2.73652E-06 | |
2236 | 63 | I/V | 144 | rs1328042181 | 0.1149 | None | gnomAD-4.0.0 | 3.18224E-06 | |
2237 | 64 | D/V | 145 | None | 0.3087 | None | gnomAD-4.0.0 | 1.59083E-06 | |
2238 | 65 | T/A | 146 | rs747377115 | 0.7334 | None | gnomAD-2.1.1 | 3.98E-06 | |
2238 | 65 | T/A | 146 | rs747377115 | 0.7334 | None | gnomAD-4.0.0 | 6.84129E-07 | |
2238 | 65 | T/K | 146 | None | 0.7334 | None | gnomAD-4.0.0 | 6.84146E-07 | |
2238 | 65 | T/M | 146 | rs201284459 | 0.7334 | None | gnomAD-2.1.1 | 1.62834E-04 | |
2238 | 65 | T/M | 146 | rs201284459 | 0.7334 | None | gnomAD-3.1.2 | 5.26E-05 | |
2238 | 65 | T/M | 146 | rs201284459 | 0.7334 | None | gnomAD-4.0.0 | 1.17733E-04 | |
2238 | 65 | T/P | 146 | rs747377115 | 0.7334 | None | gnomAD-4.0.0 | 1.23143E-05 | |
2238 | 65 | T/R | 146 | rs201284459 | 0.7334 | None | gnomAD-2.1.1 | 2.39E-05 | |
2238 | 65 | T/R | 146 | rs201284459 | 0.7334 | None | gnomAD-3.1.2 | 6.57E-06 | |
2238 | 65 | T/R | 146 | rs201284459 | 0.7334 | None | 1000 genomes | 1.99681E-04 | |
2238 | 65 | T/R | 146 | rs201284459 | 0.7334 | None | gnomAD-4.0.0 | 1.11528E-05 | |
2239 | 66 | S/A | 148 | None | 0.4792 | None | gnomAD-4.0.0 | 1.59081E-06 | |
2239 | 66 | S/F | 148 | rs1486541995 | 0.4792 | None | gnomAD-2.1.1 | 7.08E-06 | |
2239 | 66 | S/F | 148 | rs1486541995 | 0.4792 | None | gnomAD-3.1.2 | 6.57E-06 | |
2239 | 66 | S/F | 148 | rs1486541995 | 0.4792 | None | gnomAD-4.0.0 | 3.71776E-06 | |
2240 | 67 | D/E | 149 | rs149404931 | 0.1290 | None | gnomAD-2.1.1 | 1.42E-05 | |
2240 | 67 | D/E | 149 | rs149404931 | 0.1290 | None | gnomAD-3.1.2 | 3.94E-05 | |
2240 | 67 | D/E | 149 | rs149404931 | 0.1290 | None | gnomAD-4.0.0 | 3.94151E-05 | |
2240 | 67 | D/G | 149 | rs745532581 | 0.1290 | None | gnomAD-2.1.1 | 7.08E-06 | |
2240 | 67 | D/G | 149 | rs745532581 | 0.1290 | None | gnomAD-3.1.2 | 6.57E-06 | |
2240 | 67 | D/G | 149 | rs745532581 | 0.1290 | None | gnomAD-4.0.0 | 1.85904E-06 | |
2240 | 67 | D/N | 149 | rs769846959 | 0.1290 | None | gnomAD-2.1.1 | 2.83E-05 | |
2240 | 67 | D/N | 149 | rs769846959 | 0.1290 | None | gnomAD-3.1.2 | 1.31E-05 | |
2240 | 67 | D/N | 149 | rs769846959 | 0.1290 | None | gnomAD-4.0.0 | 2.43354E-05 | |
2241 | 68 | A/D | 151 | None | 0.3332 | None | gnomAD-4.0.0 | 1.59088E-06 | |
2243 | 70 | D/Y | 153 | rs138787974 | 0.4451 | None | gnomAD-2.1.1 | 2.66611E-03 | |
2243 | 70 | D/Y | 153 | rs138787974 | 0.4451 | None | gnomAD-3.1.2 | 7.17225E-03 | |
2243 | 70 | D/Y | 153 | rs138787974 | 0.4451 | None | 1000 genomes | 8.38658E-03 | |
2243 | 70 | D/Y | 153 | rs138787974 | 0.4451 | None | gnomAD-4.0.0 | 1.39629E-03 | |
2244 | 71 | Y/C | 154 | None | 0.0919 | None | gnomAD-4.0.0 | 8.40229E-06 | |
2245 | 72 | S/G | 155 | None | 0.1587 | None | gnomAD-4.0.0 | 2.40065E-06 | |
2245 | 72 | S/N | 155 | rs749033972 | 0.1587 | None | gnomAD-2.1.1 | 3.98E-06 | |
2246 | 73 | C/G | 156 | rs1484766954 | 0.0618 | None | gnomAD-2.1.1 | 3.98E-06 | |
2246 | 73 | C/G | 156 | rs1484766954 | 0.0618 | None | gnomAD-3.1.2 | 6.57E-06 | |
2246 | 73 | C/G | 156 | rs1484766954 | 0.0618 | None | gnomAD-4.0.0 | 3.84249E-06 | |
2251 | 78 | D/E | 162 | None | 0.4017 | None | gnomAD-4.0.0 | 1.36839E-06 | |
2251 | 78 | D/H | 162 | rs942953757 | 0.4017 | None | gnomAD-2.1.1 | 3.99E-06 | |
2251 | 78 | D/H | 162 | rs942953757 | 0.4017 | None | gnomAD-4.0.0 | 2.73742E-06 | |
2251 | 78 | D/N | 162 | rs942953757 | 0.4017 | None | gnomAD-3.1.2 | 6.57E-06 | |
2251 | 78 | D/N | 162 | rs942953757 | 0.4017 | None | gnomAD-4.0.0 | 6.57263E-06 | |
2251 | 78 | D/V | 162 | None | 0.4017 | None | gnomAD-4.0.0 | 1.20032E-06 | |
2253 | 80 | N/K | 165 | rs1296864074 | 0.7527 | None | gnomAD-2.1.1 | 7.97E-06 | |
2253 | 80 | N/K | 165 | rs1296864074 | 0.7527 | None | gnomAD-4.0.0 | 3.18242E-06 | |
2254 | 81 | V/D | 166 | None | 0.2454 | None | gnomAD-4.0.0 | 1.59473E-06 | |
2254 | 81 | V/I | 166 | rs1401971730 | 0.2454 | None | gnomAD-2.1.1 | 3.99E-06 | |
2254 | 81 | V/I | 166 | rs1401971730 | 0.2454 | None | gnomAD-4.0.0 | 1.3685E-06 | |
2255 | 82 | K/N | 168 | None | 0.5491 | None | gnomAD-4.0.0 | 3.43349E-06 | |
2255 | 82 | K/R | 168 | None | 0.5491 | None | gnomAD-4.0.0 | 1.59126E-06 | |
2256 | 83 | T/A | 169 | rs1385805778 | 0.1104 | None | gnomAD-2.1.1 | 3.99E-06 | |
2256 | 83 | T/M | 169 | rs780758720 | 0.1104 | None | gnomAD-2.1.1 | 1.77E-05 | |
2256 | 83 | T/M | 169 | rs780758720 | 0.1104 | None | gnomAD-3.1.2 | 1.97E-05 | |
2256 | 83 | T/M | 169 | rs780758720 | 0.1104 | None | gnomAD-4.0.0 | 2.72676E-05 | |
2257 | 84 | T/A | 171 | None | 0.3861 | None | gnomAD-4.0.0 | 1.59137E-06 | |
2257 | 84 | T/I | 171 | None | 0.3861 | None | gnomAD-4.0.0 | 6.84239E-07 | |
2257 | 84 | T/S | 171 | rs755999681 | 0.3861 | None | gnomAD-2.1.1 | 7.09E-05 | |
2257 | 84 | T/S | 171 | rs755999681 | 0.3861 | None | gnomAD-3.1.2 | 3.94E-05 | |
2257 | 84 | T/S | 171 | rs755999681 | 0.3861 | None | gnomAD-4.0.0 | 1.73518E-05 | |
2258 | 85 | A/V | 172 | rs72647881 | 0.0981 | None | gnomAD-2.1.1 | 7.98E-06 | |
2258 | 85 | A/V | 172 | rs72647881 | 0.0981 | None | gnomAD-3.1.2 | 1.97E-05 | |
2258 | 85 | A/V | 172 | rs72647881 | 0.0981 | None | gnomAD-4.0.0 | 5.12501E-06 | |
2259 | 86 | K/E | 173 | None | 0.4272 | None | gnomAD-4.0.0 | 2.05276E-06 | |
2259 | 86 | K/Q | 173 | None | 0.4272 | None | gnomAD-4.0.0 | 6.84252E-07 | |
2260 | 87 | L/I | 174 | rs370058135 | 0.1163 | None | gnomAD-2.1.1 | 2E-05 | |
2260 | 87 | L/I | 174 | rs370058135 | 0.1163 | None | gnomAD-4.0.0 | 4.78987E-06 | |
2261 | 88 | I/L | 175 | rs755035176 | 0.3908 | None | gnomAD-2.1.1 | 3.99E-06 | |
2261 | 88 | I/L | 175 | rs755035176 | 0.3908 | None | gnomAD-3.1.2 | 6.57E-06 | |
2261 | 88 | I/L | 175 | rs755035176 | 0.3908 | None | gnomAD-4.0.0 | 1.23939E-06 | |
2261 | 88 | I/T | 175 | rs751757338 | 0.3908 | None | gnomAD-2.1.1 | 7.1E-06 | |
2261 | 88 | I/T | 175 | rs751757338 | 0.3908 | None | gnomAD-3.1.2 | 6.57E-06 | |
2261 | 88 | I/T | 175 | rs751757338 | 0.3908 | None | gnomAD-4.0.0 | 3.7184E-06 | |
2261 | 88 | I/V | 175 | None | 0.3908 | None | gnomAD-4.0.0 | 6.84276E-07 | |
2262 | 89 | V/I | 177 | rs1430183288 | 0.2871 | None | gnomAD-2.1.1 | 3.99E-06 | |
2262 | 89 | V/I | 177 | rs1430183288 | 0.2871 | None | gnomAD-4.0.0 | 1.59173E-06 |