TITINdb

Map SAVs to Structure

The data displayed in the table aims to be as complete as possible and contains information for all available sources including different versions of the same source, for example, different sources of gnomAD. To avoid seeing multiple entries for the same variant, we recommend to sort by Source first.

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
26386	1	L/F	1	rs1706115983	0.6259	None	gnomAD-4.0.0	1.20032E-06
26388	3	G/E	3	None	0.2477	None	gnomAD-4.0.0	3.60097E-06
26388	3	G/R	3	rs763822931	0.2477	None	gnomAD-2.1.1	8.05E-06
26388	3	G/R	3	rs763822931	0.2477	None	gnomAD-3.1.2	1.32E-05
26388	3	G/R	3	rs763822931	0.2477	None	gnomAD-4.0.0	4.95833E-06
26389	4	P/L	4	rs760307077	0.3923	None	gnomAD-2.1.1	8.05E-06
26389	4	P/L	4	rs760307077	0.3923	None	gnomAD-4.0.0	3.18323E-06
26390	5	P/T	5	rs771933950	0.1120	None	gnomAD-2.1.1	2.01E-05
26390	5	P/T	5	rs771933950	0.1120	None	gnomAD-3.1.2	6.58E-06
26390	5	P/T	5	rs771933950	0.1120	None	gnomAD-4.0.0	1.28157E-05
26392	7	S/T	7	None	0.4863	None	gnomAD-4.0.0	6.84271E-07
26393	8	L/F	9	None	0.2459	None	gnomAD-4.0.0	1.20032E-06
26393	8	L/S	9	rs745768515	0.2459	None	gnomAD-4.0.0	2.7371E-06
26394	9	E/Q	11	rs144788732	0.6917	None	gnomAD-3.1.2	6.58E-06
26394	9	E/Q	11	rs144788732	0.6917	None	1000 genomes	1.99681E-04
26394	9	E/Q	11	rs144788732	0.6917	None	gnomAD-4.0.0	1.02504E-05
26397	12	N/D	14	rs1349397397	0.6668	None	gnomAD-4.0.0	1.20032E-06
26398	13	I/T	15	rs749071678	0.2551	None	gnomAD-2.1.1	8.05E-06
26398	13	I/T	15	rs749071678	0.2551	None	gnomAD-4.0.0	6.84272E-07
26399	14	A/V	16	None	0.1598	None	gnomAD-4.0.0	1.20032E-06
26401	16	D/N	18	None	0.4816	None	gnomAD-4.0.0	6.84274E-07
26401	16	D/Y	18	rs1427205421	0.4816	None	gnomAD-2.1.1	4.03E-06
26401	16	D/Y	18	rs1427205421	0.4816	None	gnomAD-4.0.0	1.36855E-06
26403	18	M/I	20	rs1706091561	0.0739	None	gnomAD-4.0.0	6.84282E-07
26403	18	M/K	20	rs1469438235	0.0739	None	gnomAD-2.1.1	8.05E-06
26403	18	M/K	20	rs1469438235	0.0739	None	gnomAD-4.0.0	4.77483E-06
26404	19	T/I	21	rs786205300	0.1698	None	gnomAD-2.1.1	4.03E-06
26404	19	T/I	21	rs786205300	0.1698	None	gnomAD-3.1.2	6.58E-06
26404	19	T/I	21	rs786205300	0.1698	None	gnomAD-4.0.0	1.8594E-06
26404	19	T/N	21	None	0.1698	None	gnomAD-2.1.1	4.03E-06
26404	19	T/N	21	None	0.1698	None	gnomAD-4.0.0	1.36857E-06
26405	20	V/I	22	rs769972835	0.1075	None	gnomAD-2.1.1	3.22E-05
26405	20	V/I	22	rs769972835	0.1075	None	gnomAD-3.1.2	1.97E-05
26405	20	V/I	22	rs769972835	0.1075	None	gnomAD-4.0.0	2.23121E-05
26406	21	C/Y	23	rs727505223	0.1941	None	gnomAD-4.0.0	1.20032E-06
26407	22	W/R	24	rs1018970512	0.1048	None	gnomAD-2.1.1	5.24E-05
26407	22	W/R	24	rs1018970512	0.1048	None	gnomAD-3.1.2	1.24882E-04
26407	22	W/R	24	rs1018970512	0.1048	None	gnomAD-4.0.0	4.10026E-05
26409	24	R/C	26	rs748258568	0.5570	None	gnomAD-2.1.1	2.42E-05
26409	24	R/C	26	rs748258568	0.5570	None	gnomAD-3.1.2	6.58E-06
26409	24	R/C	26	rs748258568	0.5570	None	gnomAD-4.0.0	1.3636E-05
26409	24	R/H	26	rs72648206	0.5570	None	gnomAD-2.1.1	5.68739E-04
26409	24	R/H	26	rs72648206	0.5570	None	gnomAD-3.1.2	6.7062E-04
26409	24	R/H	26	rs72648206	0.5570	None	gnomAD-4.0.0	8.57715E-04
26410	25	P/R	27	None	0.1853	None	gnomAD-4.0.0	1.59173E-06
26410	25	P/S	27	None	0.1853	None	gnomAD-4.0.0	1.20032E-06
26411	26	D/E	28	None	0.9398	None	gnomAD-4.0.0	6.84293E-07
26411	26	D/G	28	None	0.9398	None	gnomAD-4.0.0	6.84292E-07
26411	26	D/N	28	rs2154165912	0.9398	None	gnomAD-4.0.0	2.40064E-06
26411	26	D/V	28	rs755457407	0.9398	None	gnomAD-2.1.1	4.03E-06
26411	26	D/V	28	rs755457407	0.9398	None	gnomAD-4.0.0	6.84292E-07
26412	27	S/G	29	None	0.4815	None	gnomAD-4.0.0	1.36859E-06
26412	27	S/N	29	rs752040235	0.4815	None	gnomAD-2.1.1	4.03E-06
26412	27	S/N	29	rs752040235	0.4815	None	gnomAD-4.0.0	3.42143E-06
26413	28	D/E	30	None	0.3230	None	gnomAD-4.0.0	6.8429E-07
26414	29	G/C	31	None	0.4039	None	gnomAD-4.0.0	6.84291E-07
26414	29	G/D	31	rs867960496	0.4039	None	gnomAD-2.1.1	8.06E-06
26414	29	G/D	31	rs867960496	0.4039	None	gnomAD-3.1.2	2.63E-05
26414	29	G/D	31	rs867960496	0.4039	None	gnomAD-4.0.0	8.97022E-06
26414	29	G/S	31	rs1349007720	0.4039	None	gnomAD-2.1.1	4.03E-06
26414	29	G/S	31	rs1349007720	0.4039	None	gnomAD-4.0.0	6.84291E-07
26415	30	G/R	32	rs1706073598	0.6508	None	gnomAD-3.1.2	6.58E-06
26415	30	G/R	32	rs1706073598	0.6508	None	gnomAD-4.0.0	7.68945E-06
26416	31	S/R	33	None	0.2680	None	gnomAD-4.0.0	1.59176E-06
26417	32	E/D	34	rs369019463	0.7968	None	gnomAD-2.1.1	2.82E-05
26417	32	E/D	34	rs369019463	0.7968	None	gnomAD-3.1.2	3.29E-05
26417	32	E/D	34	rs369019463	0.7968	None	gnomAD-4.0.0	8.67713E-05
26417	32	E/Q	34	None	0.7968	None	gnomAD-4.0.0	2.05291E-06
26418	33	I/V	35	rs1382272786	0.1739	None	gnomAD-2.1.1	4.03E-06
26418	33	I/V	35	rs1382272786	0.1739	None	gnomAD-4.0.0	1.3686E-06
26420	35	G/C	37	None	0.1130	None	gnomAD-4.0.0	1.59187E-06
26420	35	G/D	37	None	0.1130	None	gnomAD-4.0.0	2.40065E-06
26422	37	I/L	39	rs1553590996	0.2438	None	gnomAD-4.0.0	2.73732E-06
26422	37	I/T	39	rs3731745	0.2438	None	gnomAD-2.1.1	2.57346E-02
26422	37	I/T	39	rs3731745	0.2438	None	gnomAD-3.1.2	2.023E-02
26422	37	I/T	39	rs3731745	0.2438	None	1000 genomes	2.23642E-02
26422	37	I/T	39	rs3731745	0.2438	None	gnomAD-4.0.0	2.28872E-02
26422	37	I/V	39	rs1553590996	0.2438	None	gnomAD-3.1.2	1.31E-05
26422	37	I/V	39	rs1553590996	0.2438	None	gnomAD-4.0.0	2.47925E-06
26423	38	V/A	40	rs576203363	0.1032	None	gnomAD-2.1.1	8.07E-06
26423	38	V/A	40	rs576203363	0.1032	None	gnomAD-3.1.2	6.58E-06
26423	38	V/A	40	rs576203363	0.1032	None	1000 genomes	1.99681E-04
26423	38	V/A	40	rs576203363	0.1032	None	gnomAD-4.0.0	4.95833E-06
26423	38	V/G	40	None	0.1032	None	gnomAD-4.0.0	6.8434E-07
26423	38	V/L	40	rs1706066147	0.1032	None	gnomAD-3.1.2	1.97E-05
26423	38	V/L	40	rs1706066147	0.1032	None	gnomAD-4.0.0	1.97259E-05
26424	39	E/A	41	None	0.1653	None	gnomAD-4.0.0	1.59206E-06
26424	39	E/K	41	rs1706064410	0.1653	None	gnomAD-3.1.2	6.57E-06
26424	39	E/K	41	rs1706064410	0.1653	None	gnomAD-4.0.0	6.57471E-06
26425	40	K/E	42	rs1706063163	0.1831	None	gnomAD-4.0.0	3.49016E-05
26425	40	K/I	42	rs1359744760	0.1831	None	gnomAD-2.1.1	4.03E-06
26425	40	K/I	42	rs1359744760	0.1831	None	gnomAD-4.0.0	2.05305E-06
26426	41	R/I	43	None	0.2172	None	gnomAD-4.0.0	1.20032E-06
26427	42	D/E	44	rs766994654	0.1763	None	gnomAD-2.1.1	3.22E-05
26427	42	D/E	44	rs766994654	0.1763	None	gnomAD-3.1.2	1.32E-05
26427	42	D/E	44	rs766994654	0.1763	None	gnomAD-4.0.0	6.84363E-07
26427	42	D/H	44	rs1157004476	0.1763	None	gnomAD-3.1.2	6.57E-06
26427	42	D/H	44	rs1157004476	0.1763	None	gnomAD-4.0.0	6.57462E-06
26427	42	D/N	44	rs1157004476	0.1763	None	gnomAD-2.1.1	4.03E-06
26427	42	D/N	44	rs1157004476	0.1763	None	gnomAD-4.0.0	1.59205E-06
26429	44	S/N	54	None	0.6437	None	gnomAD-4.0.0	2.40064E-06
26429	44	S/R	54	None	0.6437	None	gnomAD-4.0.0	1.59205E-06
26430	45	G/A	60	None	0.2691	None	gnomAD-4.0.0	1.20033E-06
26431	46	I/F	63	None	1.1568	None	gnomAD-4.0.0	2.40067E-06
26431	46	I/N	63	None	1.1568	None	gnomAD-4.0.0	1.59199E-06
26432	47	R/Q	64	rs770752765	0.8410	None	gnomAD-2.1.1	3.23E-05
26432	47	R/Q	64	rs770752765	0.8410	None	gnomAD-3.1.2	1.32E-05
26432	47	R/Q	64	rs770752765	0.8410	None	gnomAD-4.0.0	1.54964E-05
26433	48	W/R	65	None	0.2114	None	gnomAD-4.0.0	1.59222E-06
26434	49	I/T	66	None	0.5463	None	gnomAD-4.0.0	3.18402E-06
26436	51	C/R	68	None	0.2383	None	gnomAD-4.0.0	1.20032E-06
26436	51	C/Y	68	None	0.2383	None	gnomAD-4.0.0	2.7375E-06
26439	54	R/C	72	rs372968732	0.9190	None	gnomAD-2.1.1	2.82E-05
26439	54	R/C	72	rs372968732	0.9190	None	gnomAD-3.1.2	2.63E-05
26439	54	R/C	72	rs372968732	0.9190	None	gnomAD-4.0.0	2.9755E-05
26439	54	R/H	72	rs187941835	0.9190	None	gnomAD-2.1.1	1.61E-05
26439	54	R/H	72	rs187941835	0.9190	None	gnomAD-3.1.2	1.32E-05
26439	54	R/H	72	rs187941835	0.9190	None	1000 genomes	1.99681E-04
26439	54	R/H	72	rs187941835	0.9190	None	gnomAD-4.0.0	3.40917E-05
26440	55	R/C	75	rs55861600	0.6627	None	gnomAD-2.1.1	2.51621E-03
26440	55	R/C	75	rs55861600	0.6627	None	gnomAD-3.1.2	7.51355E-03
26440	55	R/C	75	rs55861600	0.6627	None	1000 genomes	6.58946E-03
26440	55	R/C	75	rs55861600	0.6627	None	gnomAD-4.0.0	1.471E-03
26440	55	R/H	75	rs56044609	0.6627	None	gnomAD-2.1.1	1.76438E-03
26440	55	R/H	75	rs56044609	0.6627	None	gnomAD-3.1.2	5.02513E-03
26440	55	R/H	75	rs56044609	0.6627	None	1000 genomes	4.59265E-03
26440	55	R/H	75	rs56044609	0.6627	None	gnomAD-4.0.0	1.05004E-03
26440	55	R/L	75	rs56044609	0.6627	None	gnomAD-3.1.2	6.58E-06
26440	55	R/L	75	rs56044609	0.6627	None	gnomAD-4.0.0	6.5773E-06
26441	56	I/V	77	rs1305096924	0.1812	None	gnomAD-3.1.2	6.57E-06
26441	56	I/V	77	rs1305096924	0.1812	None	gnomAD-4.0.0	6.57341E-06
26442	57	T/I	83	rs1288656149	0.6375	None	gnomAD-2.1.1	4.03E-06
26442	57	T/I	83	rs1288656149	0.6375	None	gnomAD-3.1.2	6.58E-06
26442	57	T/I	83	rs1288656149	0.6375	None	gnomAD-4.0.0	2.56379E-06
26442	57	T/R	83	None	0.6375	None	gnomAD-4.0.0	1.59234E-06
26445	60	R/C	90	rs780658084	0.6755	None	gnomAD-2.1.1	8.06E-06
26445	60	R/C	90	rs780658084	0.6755	None	gnomAD-4.0.0	7.52881E-06
26445	60	R/H	90	rs764254441	0.6755	None	gnomAD-2.1.1	5.01E-05
26445	60	R/H	90	rs764254441	0.6755	None	gnomAD-3.1.2	8.55E-05
26445	60	R/H	90	rs764254441	0.6755	None	gnomAD-4.0.0	7.19055E-05
26445	60	R/L	90	None	0.6755	None	gnomAD-4.0.0	6.84406E-07
26445	60	R/S	90	rs780658084	0.6755	None	gnomAD-2.1.1	4.03E-06
26445	60	R/S	90	rs780658084	0.6755	None	gnomAD-4.0.0	6.84437E-07
26446	61	L/I	91	None	0.1916	None	gnomAD-4.0.0	6.84399E-07
26446	61	L/V	91	None	0.1916	None	gnomAD-4.0.0	6.84399E-07
26447	62	R/G	92	None	0.6211	None	gnomAD-4.0.0	1.59217E-06
26447	62	R/K	92	None	0.6211	None	gnomAD-4.0.0	4.77661E-06
26448	63	V/G	93	rs1553590427	0.1404	None	gnomAD-4.0.0	3.42193E-06
26448	63	V/M	93	rs1380054566	0.1404	None	gnomAD-2.1.1	1.21E-05
26448	63	V/M	93	rs1380054566	0.1404	None	gnomAD-3.1.2	6.57E-06
26448	63	V/M	93	rs1380054566	0.1404	None	gnomAD-4.0.0	2.85135E-05
26450	65	G/R	96	rs752326213	0.4602	None	gnomAD-2.1.1	4.03E-06
26450	65	G/R	96	rs752326213	0.4602	None	gnomAD-3.1.2	6.57E-06
26450	65	G/R	96	rs752326213	0.4602	None	gnomAD-4.0.0	5.12723E-06
26452	67	T/K	98	rs375061238	0.3868	None	gnomAD-3.1.2	6.58E-06
26452	67	T/K	98	rs375061238	0.3868	None	gnomAD-4.0.0	6.57618E-06
26453	68	E/D	99	rs1299909025	0.4584	None	gnomAD-2.1.1	4.03E-06
26453	68	E/D	99	rs1299909025	0.4584	None	gnomAD-4.0.0	1.59214E-06
26453	68	E/K	99	None	0.4584	None	gnomAD-4.0.0	1.59227E-06
26453	68	E/V	99	None	0.4584	None	gnomAD-4.0.0	1.59213E-06
26454	69	D/Y	100	None	0.5943	None	gnomAD-4.0.0	1.59213E-06
26455	70	H/L	102	rs1706027095	0.3676	None	gnomAD-4.0.0	2.05314E-06
26455	70	H/Y	102	None	0.3676	None	gnomAD-4.0.0	6.84394E-07
26456	71	E/A	103	rs767070836	0.2683	None	gnomAD-2.1.1	1.21E-05
26456	71	E/A	103	rs767070836	0.2683	None	gnomAD-4.0.0	1.11453E-05
26456	71	E/K	103	rs1706025148	0.2683	None	gnomAD-3.1.2	6.57E-06
26456	71	E/K	103	rs1706025148	0.2683	None	gnomAD-4.0.0	1.5225E-05
26458	73	E/D	105	rs1162274016	0.0786	None	gnomAD-2.1.1	4.03E-06
26458	73	E/D	105	rs1162274016	0.0786	None	gnomAD-4.0.0	1.59216E-06
26459	74	F/C	106	None	0.1203	None	gnomAD-4.0.0	2.73749E-06
26460	75	R/G	107	rs1406730761	0.1531	None	gnomAD-2.1.1	4.03E-06
26460	75	R/G	107	rs1406730761	0.1531	None	gnomAD-4.0.0	1.36876E-06
26460	75	R/K	107	None	0.1531	None	gnomAD-4.0.0	2.40064E-06
26461	76	V/A	108	rs1351446352	0.0740	None	gnomAD-2.1.1	3.19E-05
26461	76	V/A	108	rs1351446352	0.0740	None	gnomAD-3.1.2	6.58E-06
26461	76	V/A	108	rs1351446352	0.0740	None	gnomAD-4.0.0	6.57808E-06
26461	76	V/I	108	None	0.0740	None	gnomAD-4.0.0	1.20032E-06
26462	77	S/P	109	None	0.1279	None	gnomAD-4.0.0	1.20032E-06
26463	78	A/G	110	None	0.0959	None	gnomAD-4.0.0	3.42197E-06
26464	79	E/A	111	rs766335027	0.2429	None	gnomAD-2.1.1	4.03E-06
26464	79	E/A	111	rs766335027	0.2429	None	gnomAD-4.0.0	3.18427E-06
26464	79	E/D	111	None	0.2429	None	gnomAD-4.0.0	1.20032E-06
26464	79	E/G	111	rs766335027	0.2429	None	gnomAD-2.1.1	8.06E-06
26464	79	E/G	111	rs766335027	0.2429	None	gnomAD-4.0.0	4.7764E-06
26466	81	A/G	113	rs762829887	0.6146	None	gnomAD-2.1.1	4.03E-06
26466	81	A/G	113	rs762829887	0.6146	None	gnomAD-3.1.2	6.57E-06
26466	81	A/G	113	rs762829887	0.6146	None	gnomAD-4.0.0	8.67826E-06
26467	82	A/S	114	rs773008593	0.4975	None	gnomAD-2.1.1	1.61E-05
26467	82	A/S	114	rs773008593	0.4975	None	gnomAD-4.0.0	8.8968E-06
26467	82	A/T	114	None	0.4975	None	gnomAD-4.0.0	2.05311E-06
26469	84	V/A	117	None	0.4015	None	gnomAD-4.0.0	1.592E-06
26469	84	V/I	117	rs540254651	0.4015	None	gnomAD-3.1.2	1.31E-05
26469	84	V/I	117	rs540254651	0.4015	None	1000 genomes	1.99681E-04
26469	84	V/I	117	rs540254651	0.4015	None	gnomAD-4.0.0	8.11889E-06
26471	86	E/G	119	None	0.7991	None	gnomAD-4.0.0	1.59201E-06
26471	86	E/K	119	None	0.7991	None	gnomAD-4.0.0	3.60099E-06
26473	88	S/G	121	None	0.1201	None	gnomAD-4.0.0	1.20032E-06
26473	88	S/N	121	None	0.1201	None	gnomAD-4.0.0	6.84346E-07
26474	89	P/A	122	rs761511285	0.7285	None	gnomAD-2.1.1	8.06E-06
26474	89	P/A	122	rs761511285	0.7285	None	gnomAD-4.0.0	1.23184E-05
26475	90	A/G	123	rs1706007740	0.3006	None	gnomAD-4.0.0	1.59212E-06
26475	90	A/P	123	rs1245328296	0.3006	None	gnomAD-2.1.1	4.03E-06
26475	90	A/P	123	rs1245328296	0.3006	None	gnomAD-4.0.0	1.3687E-06
26476	91	T/I	124	rs1457082371	0.1679	None	gnomAD-4.0.0	1.59211E-06
26476	91	T/P	124	None	0.1679	None	gnomAD-4.0.0	1.20032E-06
26477	92	V/I	125	rs1706005880	0.6213	None	gnomAD-4.0.0	4.10615E-06
26478	93	Y/C	126	rs1053235966	0.2634	None	gnomAD-4.0.0	1.59203E-06
26478	93	Y/D	126	rs768735283	0.2634	None	gnomAD-2.1.1	4.03E-06
26478	93	Y/D	126	rs768735283	0.2634	None	gnomAD-4.0.0	1.59209E-06
26479	94	Y/C	127	None	0.2776	None	gnomAD-4.0.0	1.59216E-06
26479	94	Y/F	127	rs747150576	0.2776	None	gnomAD-2.1.1	4.03E-06
26479	94	Y/F	127	rs747150576	0.2776	None	gnomAD-4.0.0	1.59216E-06
26480	95	K/N	129	None	0.3148	None	gnomAD-4.0.0	2.40064E-06
26481	96	A/D	130	None	0.0642	None	gnomAD-4.0.0	1.59236E-06
26481	96	A/G	130	None	0.0642	None	gnomAD-4.0.0	1.59236E-06
26481	96	A/V	130	rs1320046233	0.0642	None	gnomAD-2.1.1	8.06E-06
26481	96	A/V	130	rs1320046233	0.0642	None	gnomAD-3.1.2	6.58E-06
26481	96	A/V	130	rs1320046233	0.0642	None	gnomAD-4.0.0	3.84587E-06

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
26386	1	L/F	rs1706115983	0.6259	gnomAD-4.0.0	1	None	0.171	0.1691	24.6	N	None	0.54	0.01622	-0.711	0.1477	-0.9022	0.0962467611548	1.665	0.948644	0.352	0.257292322809	0.087	0.642835795879	-2.32	0.068	0.255	0.216	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
26388	3	G/E	None	0.2477	gnomAD-4.0.0	3	None	0.4619	0.4908	34.0	N	None	0.49	0.028893	-2.187	0.4354	0.031	0.510414320493	3.135	0.999999	0.481	0.473774312618	0.999	0.837695121765	-4.99	0.352	0.821	0.095	None	None	3.60097E-06	0	0	0	0	None	0	0	3.60097E-06	3.93751E-06	0	0	None	N	None
26388	3	G/R	rs763822931	0.2477	gnomAD-2.1.1	3	None	0.691	0.7259	27.9	N	-0.532	0.42	0.026593	-0.861	0.4065	-0.083	0.494755770336	3.825	0.999999	0.551	0.613362904753	0.999	0.845995783806	-5.34	0.415	0.849	0.01	None	None	8.05E-06	0	0	0	0	None	0	None	8.05E-06	0	1.78E-05	0	None	N	None
26388	3	G/R	rs763822931	0.2477	gnomAD-3.1.2	3	None	0.691	0.7259	27.9	N	-0.532	0.42	0.026593	-0.861	0.4065	-0.083	0.494755770336	3.825	0.999999	0.551	0.613362904753	0.999	0.845995783806	-5.34	0.415	0.849	0.01	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	N	None
26388	3	G/R	rs763822931	0.2477	gnomAD-4.0.0	3	None	0.691	0.7259	27.9	N	-0.532	0.42	0.026593	-0.861	0.4065	-0.083	0.494755770336	3.825	0.999999	0.551	0.613362904753	0.999	0.845995783806	-5.34	0.415	0.849	0.01	None	None	4.95833E-06	0	0	0	0	None	0	0	4.95833E-06	6.78156E-06	0	0	None	N	None
26389	4	P/L	rs760307077	0.3923	gnomAD-2.1.1	4	None	0.1581	0.1604	35.0	N	-0.72	0.24	0.042063	-0.839	0.4381	0.1189	0.377742335444	3.32	0.999999	0.464	0.651006993216	0.967	0.717906594276	-7.19	0.496	0.745	0.007	None	None	8.05E-06	0	0	0	0	None	6.54E-05	None	8.05E-06	0	0	0	None	N	None
26389	4	P/L	rs760307077	0.3923	gnomAD-4.0.0	4	None	0.1581	0.1604	35.0	N	-0.72	0.24	0.042063	-0.839	0.4381	0.1189	0.377742335444	3.32	0.999999	0.464	0.651006993216	0.967	0.717906594276	-7.19	0.496	0.745	0.007	None	None	3.18323E-06	0	0	0	0	None	0	0	3.18323E-06	0	2.86566E-05	0	None	N	None
26390	5	P/T	rs771933950	0.1120	gnomAD-2.1.1	5	None	0.9108	0.9155	28.9	D	-2.687	-0.64	0.194354	-2.578	0.7551	0.849	0.48919594472	4.425	1.0	0.665	0.799015929191	1.0	0.732840538025	-6.41	0.704	0.829	0.004	None	None	2.01E-05	0	0	0	0	None	0	None	2.01E-05	0	4.45E-05	0	None	N	None
26390	5	P/T	rs771933950	0.1120	gnomAD-3.1.2	5	None	0.9108	0.9155	28.9	D	-2.687	-0.64	0.194354	-2.578	0.7551	0.849	0.48919594472	4.425	1.0	0.665	0.799015929191	1.0	0.732840538025	-6.41	0.704	0.829	0.004	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
26390	5	P/T	rs771933950	0.1120	gnomAD-4.0.0	5	None	0.9108	0.9155	28.9	D	-2.687	-0.64	0.194354	-2.578	0.7551	0.849	0.48919594472	4.425	1.0	0.665	0.799015929191	1.0	0.732840538025	-6.41	0.704	0.829	0.004	None	None	1.28157E-05	0	0	0	0	None	0	0	1.28157E-05	1.91503E-05	0	5.69152E-05	None	N	None
26392	7	S/T	None	0.4863	gnomAD-4.0.0	7	None	0.078	0.0754	22.4	N	None	0.43	0.010825	-0.348	0.0822	-0.9847	0.0891353627514	0.085	0.999962	0.342	0.0401082797425	0.042	0.507965564728	-1.69	0.035	0.269	0.647	None	None	6.84271E-07	0	0	0	0	None	0	0	6.84271E-07	8.99546E-07	0	0	None	N	None
26393	8	L/F	None	0.2459	gnomAD-4.0.0	9	None	0.5373	0.4941	24.5	N	None	-0.1	0.021022	-1.449	0.3144	-0.3321	0.384010845626	1.735	0.754808	0.526	0.446310458034	0.901	0.720517277718	-2.84	0.252	0.711	0.172	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26393	8	L/S	rs745768515	0.2459	gnomAD-4.0.0	9	None	0.7436	0.7084	34.0	N	-3.001	-0.16	0.034084	-2.423	0.4049	-0.4682	0.370025690484	3.12	0.986256	0.618	0.543076009278	0.901	0.745040714741	-3.94	0.443	0.772	0.029	None	None	2.7371E-06	5.978E-05	0	0	0	None	0	1.73491E-04	2.7371E-06	0	0	1.657E-05	None	N	None
26394	9	E/Q	rs144788732	0.6917	gnomAD-3.1.2	11	None	0.2214	0.2717	None	N	-0.139	None	None	-0.122	None	None	None	None	None	None	None	1.0	None	None	0.199	0.659	None	None	None	6.58E-06	0	0	0	1.93424E-04	None	0	0	6.58E-06	0	0	0	None	I	None
26394	9	E/Q	rs144788732	0.6917	1000 genomes	11	None	0.2214	0.2717	None	N	-0.139	None	None	-0.122	None	None	None	None	None	None	None	1.0	None	None	0.199	0.659	None	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	I	None
26394	9	E/Q	rs144788732	0.6917	gnomAD-4.0.0	11	None	0.2214	0.2717	None	N	-0.139	None	None	-0.122	None	None	None	None	None	None	None	1.0	None	None	0.199	0.659	None	None	None	1.02504E-05	0	0	0	1.94156E-04	None	0	0	1.02504E-05	0	0	0	None	I	None
26397	12	N/D	rs1349397397	0.6668	gnomAD-4.0.0	14	None	0.4383	0.3889	24.8	N	None	0.44	0.014653	0.127	0.1447	-0.7963	0.327312460681	0.61	0.999982	0.518	0.256283259241	0.958	0.761539578438	-3.6	0.399	0.434	0.222	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26398	13	I/T	rs749071678	0.2551	gnomAD-2.1.1	15	None	0.2122	0.1702	26.0	N	-1.494	0.31	0.025613	-1.586	0.2398	-0.6335	0.34465612912	2.115	0.999974	0.544	0.615014731015	0.892	0.807198822498	-3.75	0.363	0.586	0.024	None	None	8.05E-06	0	0	0	0	None	6.54E-05	None	8.05E-06	0	0	0	None	N	None
26398	13	I/T	rs749071678	0.2551	gnomAD-4.0.0	15	None	0.2122	0.1702	26.0	N	-1.494	0.31	0.025613	-1.586	0.2398	-0.6335	0.34465612912	2.115	0.999974	0.544	0.615014731015	0.892	0.807198822498	-3.75	0.363	0.586	0.024	None	None	6.84272E-07	0	0	0	0	None	0	0	6.84272E-07	0	1.15937E-05	0	None	N	None
26399	14	A/V	None	0.1598	gnomAD-4.0.0	16	None	0.2589	0.2099	31.0	N	None	0.4	0.027821	-0.74	0.1139	-0.9597	0.117304707431	0.35	0.993999	0.456	0.247322355667	0.379	0.640094161034	-2.43	0.301	0.293	0.016	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26401	16	D/N	None	0.4816	gnomAD-4.0.0	18	None	0.2651	0.2595	33.0	N	None	0.48	0.030391	0.034	0.2445	-0.6271	0.412108884712	1.585	1.0	0.508	0.227260227426	0.988	0.781040251255	-3.65	0.331	0.655	0.12	None	None	6.84274E-07	0	0	0	0	None	0	0	6.84274E-07	8.99538E-07	0	0	None	N	None
26401	16	D/Y	rs1427205421	0.4816	gnomAD-2.1.1	18	None	0.6251	0.6193	33.0	N	-0.492	0.33	0.032201	-0.465	0.5075	0.1603	0.500172276967	3.765	1.0	0.534	0.65374614097	0.999	0.786584973335	-6.79	0.426	0.692	0.004	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
26401	16	D/Y	rs1427205421	0.4816	gnomAD-4.0.0	18	None	0.6251	0.6193	33.0	N	-0.492	0.33	0.032201	-0.465	0.5075	0.1603	0.500172276967	3.765	1.0	0.534	0.65374614097	0.999	0.786584973335	-6.79	0.426	0.692	0.004	None	None	1.36855E-06	0	0	0	0	None	0	0	1.36855E-06	1.79908E-06	0	0	None	N	None
26403	18	M/I	rs1706091561	0.0739	gnomAD-4.0.0	20	None	0.8609	0.7779	28.5	N	None	0.57	0.033333	-0.563	0.2093	-0.5872	0.474458688699	0.635	1.0	0.528	0.50857664894	0.985	0.740040540695	-2.89	0.417	0.641	0.141	None	None	6.84282E-07	0	0	0	0	None	0	0	6.84282E-07	8.99539E-07	0	0	None	N	None
26403	18	M/K	rs1469438235	0.0739	gnomAD-2.1.1	20	None	0.994	0.9907	33.0	N	-0.272	0.37	0.054875	-1.193	0.4386	0.0643	0.567138394775	3.58	1.0	0.74	0.681219007559	0.994	0.796903073788	-4.49	0.65	0.795	0.004	None	None	8.05E-06	0	5.8E-05	0	0	None	0	None	8.05E-06	0	0	0	None	N	None
26403	18	M/K	rs1469438235	0.0739	gnomAD-4.0.0	20	None	0.994	0.9907	33.0	N	-0.272	0.37	0.054875	-1.193	0.4386	0.0643	0.567138394775	3.58	1.0	0.74	0.681219007559	0.994	0.796903073788	-4.49	0.65	0.795	0.004	None	None	4.77483E-06	0	6.86091E-05	0	0	None	0	0	4.77483E-06	0	0	0	None	N	None
26404	19	T/I	rs786205300	0.1698	gnomAD-2.1.1	21	None	0.3942	0.3911	33.0	D	0.179	0.3	0.023345	0.096	0.3793	-0.3162	0.480749730577	1.98	1.0	0.569	0.482792760554	1.0	0.819770634174	-4.29	0.445	0.788	0.1	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
26404	19	T/I	rs786205300	0.1698	gnomAD-3.1.2	21	None	0.3942	0.3911	33.0	D	0.179	0.3	0.023345	0.096	0.3793	-0.3162	0.480749730577	1.98	1.0	0.569	0.482792760554	1.0	0.819770634174	-4.29	0.445	0.788	0.1	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
26404	19	T/I	rs786205300	0.1698	gnomAD-4.0.0	21	None	0.3942	0.3911	33.0	D	0.179	0.3	0.023345	0.096	0.3793	-0.3162	0.480749730577	1.98	1.0	0.569	0.482792760554	1.0	0.819770634174	-4.29	0.445	0.788	0.1	None	None	1.8594E-06	0	0	0	0	None	0	0	1.8594E-06	2.54308E-06	0	0	None	N	None
26404	19	T/N	None	0.1698	gnomAD-2.1.1	21	None	0.703	0.7081	32.0	N	-1.539	0.3	0.014399	-1.404	0.4404	-0.1181	0.494608543549	2.305	1.0	0.586	0.455173453901	1.0	0.791770756245	-3.7	0.442	0.68	0.004	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
26404	19	T/N	None	0.1698	gnomAD-4.0.0	21	None	0.703	0.7081	32.0	N	-1.539	0.3	0.014399	-1.404	0.4404	-0.1181	0.494608543549	2.305	1.0	0.586	0.455173453901	1.0	0.791770756245	-3.7	0.442	0.68	0.004	None	None	1.36857E-06	0	2.23684E-05	0	0	None	0	0	1.36857E-06	8.99548E-07	0	0	None	N	None
26405	20	V/I	rs769972835	0.1075	gnomAD-2.1.1	22	None	0.0751	0.0725	None	N	0.01	None	None	-0.225	None	None	None	None	None	None	None	0.901	None	None	0.106	0.291	None	None	None	3.22E-05	1.29416E-04	0	0	0	None	3.27E-05	None	3.22E-05	1.85632E-04	8.92E-06	0	None	N	None
26405	20	V/I	rs769972835	0.1075	gnomAD-3.1.2	22	None	0.0751	0.0725	None	N	0.01	None	None	-0.225	None	None	None	None	None	None	None	0.901	None	None	0.106	0.291	None	None	None	1.97E-05	7.24E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	N	None
26405	20	V/I	rs769972835	0.1075	gnomAD-4.0.0	22	None	0.0751	0.0725	None	N	0.01	None	None	-0.225	None	None	None	None	None	None	None	0.901	None	None	0.106	0.291	None	None	None	2.23121E-05	4.00609E-05	0	0	0	None	6.2498E-05	0	2.23121E-05	2.03444E-05	3.29366E-05	3.20287E-05	None	N	None
26406	21	C/Y	rs727505223	0.1941	gnomAD-4.0.0	23	None	0.5682	0.6772	31.0	N	None	0.45	0.020546	-1.09	0.3157	-0.3597	0.53903598711	2.395	0.999982	0.463	0.789754116976	0.97	0.845474243164	-7.45	0.349	0.746	0.076	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
26407	22	W/R	rs1018970512	0.1048	gnomAD-2.1.1	24	None	0.9995	0.9996	34.0	D	-2.26	-2.1	0.36164	-2.704	0.9006	1.0816	0.615612516959	4.835	1.0	0.866	0.920412695238	1.0	0.841638028622	-10.73	0.92	0.903	None	None	None	5.24E-05	0	3.76943E-04	0	0	None	0	None	5.24E-05	0	0	0	None	N	None
26407	22	W/R	rs1018970512	0.1048	gnomAD-3.1.2	24	None	0.9995	0.9996	34.0	D	-2.26	-2.1	0.36164	-2.704	0.9006	1.0816	0.615612516959	4.835	1.0	0.866	0.920412695238	1.0	0.841638028622	-10.73	0.92	0.903	None	None	None	1.24882E-04	0	1.24606E-03	0	0	None	0	0	1.24882E-04	0	0	0	None	N	None
26407	22	W/R	rs1018970512	0.1048	gnomAD-4.0.0	24	None	0.9995	0.9996	34.0	D	-2.26	-2.1	0.36164	-2.704	0.9006	1.0816	0.615612516959	4.835	1.0	0.866	0.920412695238	1.0	0.841638028622	-10.73	0.92	0.903	None	None	None	4.10026E-05	0	5.42667E-04	0	0	None	0	0	4.10026E-05	0	0	0	None	N	None
26409	24	R/C	rs748258568	0.5570	gnomAD-2.1.1	26	None	0.3414	0.3817	34.0	N	-0.466	0.37	0.069851	-0.781	0.3895	-0.0789	0.509567048614	3.205	0.999971	0.586	0.66441189913	0.999	0.769777297974	-5.43	0.402	0.709	0.006	None	None	2.42E-05	6.47E-05	2.9E-05	0	0	None	1.30719E-04	None	2.42E-05	0	0	0	None	N	None
26409	24	R/C	rs748258568	0.5570	gnomAD-3.1.2	26	None	0.3414	0.3817	34.0	N	-0.466	0.37	0.069851	-0.781	0.3895	-0.0789	0.509567048614	3.205	0.999971	0.586	0.66441189913	0.999	0.769777297974	-5.43	0.402	0.709	0.006	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
26409	24	R/C	rs748258568	0.5570	gnomAD-4.0.0	26	None	0.3414	0.3817	34.0	N	-0.466	0.37	0.069851	-0.781	0.3895	-0.0789	0.509567048614	3.205	0.999971	0.586	0.66441189913	0.999	0.769777297974	-5.43	0.402	0.709	0.006	None	None	1.3636E-05	2.67158E-05	1.66789E-05	0	0	None	0	0	1.3636E-05	3.39078E-06	1.64716E-04	0	None	N	None
26409	24	R/H	rs72648206	0.5570	gnomAD-2.1.1	26	None	0.1884	0.2152	None	N	-1.254	None	None	-1.434	None	None	None	None	None	None	None	1.0	None	None	0.355	0.643	None	None	None	5.68739E-04	2.07056E-04	1.13231E-04	2.90473E-04	2.57017E-04	None	3.92157E-04	None	5.68739E-04	0	9.95516E-04	4.21704E-04	None	N	None
26409	24	R/H	rs72648206	0.5570	gnomAD-3.1.2	26	None	0.1884	0.2152	None	N	-1.254	None	None	-1.434	None	None	None	None	None	None	None	1.0	None	None	0.355	0.643	None	None	None	6.7062E-04	1.68935E-04	1.96721E-04	0	3.86698E-04	None	0	0	6.7062E-04	1.294E-03	2.07297E-04	4.77555E-04	None	N	None
26409	24	R/H	rs72648206	0.5570	gnomAD-4.0.0	26	None	0.1884	0.2152	None	N	-1.254	None	None	-1.434	None	None	None	None	None	None	None	1.0	None	None	0.355	0.643	None	None	None	8.57715E-04	1.73315E-04	1.33387E-04	6.75767E-05	1.33881E-04	None	0	1.65017E-04	8.57715E-04	1.09267E-03	3.95283E-04	4.64253E-04	None	N	None
26410	25	P/R	None	0.1853	gnomAD-4.0.0	27	None	0.9975	0.9946	34.0	D	None	-0.87	0.091087	-1.256	0.7094	0.6104	0.4773412541	4.05	1.0	0.785	0.669250944419	1.0	0.757096588612	-7.41	0.736	0.889	None	None	None	1.59173E-06	0	0	0	0	None	0	0	1.59173E-06	0	0	3.02554E-05	None	N	None
26410	25	P/S	None	0.1853	gnomAD-4.0.0	27	None	0.9903	0.9816	29.0	D	None	-0.83	0.085436	-2.147	0.6641	0.4389	0.466644225527	3.175	1.0	0.712	0.581534369529	1.0	0.712207555771	-6.68	0.68	0.861	None	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
26411	26	D/E	None	0.9398	gnomAD-4.0.0	28	None	0.0929	0.0974	24.2	N	None	0.51	0.014761	-0.281	0.052	-1.1095	0.0864687688196	-0.545	0.896697	0.409	0.0762999501168	0.067	0.535790145397	-1.83	0.079	0.239	0.843	None	None	6.84293E-07	0	0	0	0	None	0	0	6.84293E-07	8.99552E-07	0	0	None	I	None
26411	26	D/G	None	0.9398	gnomAD-4.0.0	28	None	0.1482	0.1479	35.0	N	None	0.38	0.035283	-0.059	0.1819	-0.7185	0.384708731815	-0.02	0.999999	0.47	0.305730143919	0.958	0.516901016235	-4.96	0.421	0.656	0.022	None	None	6.84292E-07	0	0	0	0	None	0	0	6.84292E-07	8.99544E-07	0	0	None	I	None
26411	26	D/N	rs2154165912	0.9398	gnomAD-4.0.0	28	None	0.1	0.1011	26.5	N	None	0.4	0.050565	0.293	0.2435	-0.6449	0.356357889553	1.195	1.0	0.42	0.26547132957	0.988	0.563178420067	-3.23	0.261	0.7	0.026	None	None	2.40064E-06	0	0	0	0	None	0	6.17284E-04	2.40064E-06	1.3125E-06	0	0	None	I	None
26411	26	D/V	rs755457407	0.9398	gnomAD-2.1.1	28	None	0.1105	0.1113	35.0	N	0.447	0.38	0.047938	0.226	0.1994	-0.6623	0.47277561626	0.09	1.0	0.515	0.502691689211	0.994	0.496577262878	-5.86	0.477	0.739	0.015	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	I	None
26411	26	D/V	rs755457407	0.9398	gnomAD-4.0.0	28	None	0.1105	0.1113	35.0	N	0.447	0.38	0.047938	0.226	0.1994	-0.6623	0.47277561626	0.09	1.0	0.515	0.502691689211	0.994	0.496577262878	-5.86	0.477	0.739	0.015	None	None	6.84292E-07	0	0	0	0	None	0	0	6.84292E-07	8.99544E-07	0	0	None	I	None
26412	27	S/G	None	0.4815	gnomAD-4.0.0	29	None	0.11	0.1183	25.5	N	None	0.54	0.045618	-0.522	0.1656	-0.7574	0.0963513489985	1.935	0.777573	0.38	0.162503812791	0.101	0.526773512363	-2.91	0.086	0.265	0.022	None	None	1.36859E-06	0	0	0	0	None	0	3.46741E-04	1.36859E-06	0	0	0	None	I	None
26412	27	S/N	rs752040235	0.4815	gnomAD-2.1.1	29	None	0.1067	0.1095	23.1	N	0.076	0.6	0.015176	-0.214	0.1083	-0.9447	0.0786034928776	0.26	0.865081	0.372	0.141422826196	0.002	0.608027160168	-2.27	0.048	0.139	0.033	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	4.64E-05	0	0	None	I	None
26412	27	S/N	rs752040235	0.4815	gnomAD-4.0.0	29	None	0.1067	0.1095	23.1	N	0.076	0.6	0.015176	-0.214	0.1083	-0.9447	0.0786034928776	0.26	0.865081	0.372	0.141422826196	0.002	0.608027160168	-2.27	0.048	0.139	0.033	None	None	3.42143E-06	0	0	0	0	None	1.87322E-05	0	3.42143E-06	3.59817E-06	0	0	None	I	None
26413	28	D/E	None	0.3230	gnomAD-4.0.0	30	None	0.8455	0.8273	27.1	N	None	0.37	0.020369	-0.494	0.3326	-0.4023	0.364596557504	2.995	0.99947	0.459	0.469165163779	0.989	0.6306899786	-3.15	0.299	0.499	0.004	None	None	6.8429E-07	0	0	0	0	None	0	1.7337E-04	6.8429E-07	0	0	0	None	I	None
26414	29	G/C	None	0.4039	gnomAD-4.0.0	31	None	0.9882	0.9823	34.0	D	None	0.37	0.280307	-0.734	0.5614	0.4672	0.478569009243	4.34	1.0	0.754	0.686737365345	1.0	0.718203186989	-7.2	0.725	0.827	None	None	None	6.84291E-07	0	0	0	0	None	0	0	6.84291E-07	8.99546E-07	0	0	None	I	None
26414	29	G/D	rs867960496	0.4039	gnomAD-2.1.1	31	None	0.9967	0.9943	31.0	N	-0.173	0.45	0.044526	-0.441	0.4774	0.1156	0.527275360279	3.535	1.0	0.734	0.40749426699	1.0	0.754739403725	-5.53	0.702	0.83	None	None	None	8.06E-06	6.49E-05	0	0	5.59E-05	None	0	None	8.06E-06	0	0	0	None	I	None
26414	29	G/D	rs867960496	0.4039	gnomAD-3.1.2	31	None	0.9967	0.9943	31.0	N	-0.173	0.45	0.044526	-0.441	0.4774	0.1156	0.527275360279	3.535	1.0	0.734	0.40749426699	1.0	0.754739403725	-5.53	0.702	0.83	None	None	None	2.63E-05	9.66E-05	0	0	0	None	0	0	2.63E-05	0	0	0	None	I	None
26414	29	G/D	rs867960496	0.4039	gnomAD-4.0.0	31	None	0.9967	0.9943	31.0	N	-0.173	0.45	0.044526	-0.441	0.4774	0.1156	0.527275360279	3.535	1.0	0.734	0.40749426699	1.0	0.754739403725	-5.53	0.702	0.83	None	None	None	8.97022E-06	8.46253E-05	0	0	2.4273E-05	None	0	0	8.97022E-06	0	0	2.84576E-05	None	I	None
26414	29	G/S	rs1349007720	0.4039	gnomAD-2.1.1	31	None	0.937	0.9091	33.0	D	-0.085	0.46	0.069053	-0.278	0.5195	0.2959	0.463496485926	3.535	1.0	0.649	0.393775345888	1.0	0.679297566414	-4.83	0.584	0.809	None	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	I	None
26414	29	G/S	rs1349007720	0.4039	gnomAD-4.0.0	31	None	0.937	0.9091	33.0	D	-0.085	0.46	0.069053	-0.278	0.5195	0.2959	0.463496485926	3.535	1.0	0.649	0.393775345888	1.0	0.679297566414	-4.83	0.584	0.809	None	None	None	6.84291E-07	0	0	0	0	None	0	0	6.84291E-07	8.99546E-07	0	0	None	I	None
26415	30	G/R	rs1706073598	0.6508	gnomAD-3.1.2	32	None	0.878	0.8632	27.8	D	None	-0.14	0.103882	-0.117	0.571	0.3107	0.506463245118	3.32	1.0	0.571	0.685279086442	1.0	0.700005829334	-6.26	0.647	0.791	None	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
26415	30	G/R	rs1706073598	0.6508	gnomAD-4.0.0	32	None	0.878	0.8632	27.8	D	None	-0.14	0.103882	-0.117	0.571	0.3107	0.506463245118	3.32	1.0	0.571	0.685279086442	1.0	0.700005829334	-6.26	0.647	0.791	None	None	None	7.68945E-06	0	8.47946E-05	0	0	None	0	0	7.68945E-06	2.39371E-06	0	0	None	I	None
26416	31	S/R	None	0.2680	gnomAD-4.0.0	33	None	0.945	0.9472	29.3	N	None	0.38	0.025901	-0.397	0.2475	-0.6425	0.332911858557	2.85	0.99953	0.485	0.299770980665	0.89	0.682287096977	-3.55	0.423	0.599	0.003	None	None	1.59176E-06	0	0	0	0	None	0	0	1.59176E-06	0	0	3.02554E-05	None	I	None
26417	32	E/D	rs369019463	0.7968	gnomAD-2.1.1	34	None	0.0971	0.1062	23.4	N	0.084	0.35	0.015324	-0.311	0.1229	-0.9915	0.080175271313	1.215	0.997071	0.41	0.170165803431	0.014	0.68652755022	-2.43	0.034	0.192	0.081	None	None	2.82E-05	0	0	0	0	None	0	None	2.82E-05	0	6.24E-05	0	None	I	None
26417	32	E/D	rs369019463	0.7968	gnomAD-3.1.2	34	None	0.0971	0.1062	23.4	N	0.084	0.35	0.015324	-0.311	0.1229	-0.9915	0.080175271313	1.215	0.997071	0.41	0.170165803431	0.014	0.68652755022	-2.43	0.034	0.192	0.081	None	None	3.29E-05	4.83E-05	0	0	0	None	0	0	3.29E-05	4.41E-05	0	0	None	I	None
26417	32	E/D	rs369019463	0.7968	gnomAD-4.0.0	34	None	0.0971	0.1062	23.4	N	0.084	0.35	0.015324	-0.311	0.1229	-0.9915	0.080175271313	1.215	0.997071	0.41	0.170165803431	0.014	0.68652755022	-2.43	0.034	0.192	0.081	None	None	8.67713E-05	4.00588E-05	0	0	0	None	0	0	8.67713E-05	1.14439E-04	0	3.20307E-05	None	I	None
26417	32	E/Q	None	0.7968	gnomAD-4.0.0	34	None	0.2895	0.2883	27.7	N	None	0.31	0.025086	0.014	0.2764	-0.4858	0.34876332092	1.975	0.999515	0.465	0.238096912614	0.942	0.676746189594	-2.35	0.262	0.546	0.017	None	None	2.05291E-06	0	0	0	0	None	0	1.7337E-04	2.05291E-06	8.99549E-07	0	1.657E-05	None	I	None
26418	33	I/V	rs1382272786	0.1739	gnomAD-2.1.1	35	None	0.1598	0.1901	31.0	N	-1.613	0.21	0.006052	-1.563	0.3558	-0.3181	0.422359933901	1.645	0.999969	0.582	0.599423059063	0.993	0.688784122467	-0.78	0.269	0.387	0.12	None	None	4.03E-06	0	0	0	5.59E-05	None	0	None	4.03E-06	0	0	0	None	I	None
26418	33	I/V	rs1382272786	0.1739	gnomAD-4.0.0	35	None	0.1598	0.1901	31.0	N	-1.613	0.21	0.006052	-1.563	0.3558	-0.3181	0.422359933901	1.645	0.999969	0.582	0.599423059063	0.993	0.688784122467	-0.78	0.269	0.387	0.12	None	None	1.3686E-06	0	0	0	5.04414E-05	None	0	0	1.3686E-06	0	0	0	None	I	None
26420	35	G/C	None	0.1130	gnomAD-4.0.0	37	None	0.5134	0.4707	32.0	D	None	0.08	0.044049	-0.767	0.5244	0.2144	0.478569009243	3.695	1.0	0.667	0.66885242914	1.0	0.791203856468	-6.93	0.557	0.804	0.001	None	None	1.59187E-06	0	0	0	0	None	0	0	1.59187E-06	2.85907E-06	0	0	None	N	None
26420	35	G/D	None	0.1130	gnomAD-4.0.0	37	None	0.9013	0.8876	28.6	N	None	0.14	0.048336	-1.685	0.5033	0.1277	0.527275360279	3.29	1.0	0.724	0.398283496042	1.0	0.829773664474	-5.3	0.601	0.839	0.011	None	None	2.40065E-06	0	0	0	0	None	0	0	2.40065E-06	1.3125E-06	0	3.66327E-05	None	N	None
26422	37	I/L	rs1553590996	0.2438	gnomAD-4.0.0	39	None	0.1378	0.1565	25.8	N	None	0.48	0.014952	-1.089	0.161	-0.8259	0.157870097519	2.17	0.999809	0.369	0.559156356702	0.63	0.626691937447	-1.67	0.207	0.479	0.106	None	None	2.73732E-06	0	0	0	1.00939E-04	None	0	0	2.73732E-06	0	0	0	None	N	None
26422	37	I/T	rs3731745	0.2438	gnomAD-2.1.1	39	None	0.2075	0.1993	None	N	-2.683	None	None	-2.148	None	None	None	None	None	None	None	0.983	None	None	0.404	0.671	None	None	None	2.57346E-02	4.85155E-03	3.35052E-02	1.46289E-02	6.12056E-02	None	6.04733E-03	None	2.57346E-02	4.7937E-02	2.33536E-02	2.65748E-02	None	N	None
26422	37	I/T	rs3731745	0.2438	gnomAD-3.1.2	39	None	0.2075	0.1993	None	N	-2.683	None	None	-2.148	None	None	None	None	None	None	None	0.983	None	None	0.404	0.671	None	None	None	2.023E-02	4.49189E-03	2.19131E-02	1.90311E-02	6.10465E-02	None	4.45974E-02	6.32911E-03	2.023E-02	2.3392E-02	8.28844E-03	1.95985E-02	None	N	None
26422	37	I/T	rs3731745	0.2438	1000 genomes	39	None	0.2075	0.1993	None	N	-2.683	None	None	-2.148	None	None	None	None	None	None	None	0.983	None	None	0.404	0.671	None	None	None	2.23642E-02	8E-04	2.45E-02	None	6.05E-02	2.68E-02	None	None	2.23642E-02	None	6.1E-03	None	None	N	None
26422	37	I/T	rs3731745	0.2438	gnomAD-4.0.0	39	None	0.2075	0.1993	None	N	-2.683	None	None	-2.148	None	None	None	None	None	None	None	0.983	None	None	0.404	0.671	None	None	None	2.28872E-02	4.29448E-03	2.94029E-02	1.48689E-02	6.3117E-02	None	4.77173E-02	9.89772E-03	2.28872E-02	2.24368E-02	6.71981E-03	2.17106E-02	None	N	None
26422	37	I/V	rs1553590996	0.2438	gnomAD-3.1.2	39	None	0.0737	0.0733	24.9	N	None	0.46	0.007768	-1.453	0.1138	-0.9552	0.16140204247	0.905	0.999577	0.34	0.513337797588	0.598	0.546332716942	-0.63	0.143	0.487	0.206	None	None	1.31E-05	0	1.3113E-04	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
26422	37	I/V	rs1553590996	0.2438	gnomAD-4.0.0	39	None	0.0737	0.0733	24.9	N	None	0.46	0.007768	-1.453	0.1138	-0.9552	0.16140204247	0.905	0.999577	0.34	0.513337797588	0.598	0.546332716942	-0.63	0.143	0.487	0.206	None	None	2.47925E-06	0	3.336E-05	0	0	None	0	0	2.47925E-06	1.69539E-06	0	0	None	N	None
26423	38	V/A	rs576203363	0.1032	gnomAD-2.1.1	40	None	0.6677	0.6217	26.9	D	-2.538	-0.34	0.029284	-2.442	0.5072	0.3267	0.295545237065	3.8	0.999919	0.712	0.650396906566	0.892	0.699861347675	-3.1	0.602	0.599	0.003	None	None	8.07E-06	0	0	0	0	None	6.54E-05	None	8.07E-06	0	0	0	None	N	None
26423	38	V/A	rs576203363	0.1032	gnomAD-3.1.2	40	None	0.6677	0.6217	26.9	D	-2.538	-0.34	0.029284	-2.442	0.5072	0.3267	0.295545237065	3.8	0.999919	0.712	0.650396906566	0.892	0.699861347675	-3.1	0.602	0.599	0.003	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	0	2.07383E-04	0	None	N	None
26423	38	V/A	rs576203363	0.1032	1000 genomes	40	None	0.6677	0.6217	26.9	D	-2.538	-0.34	0.029284	-2.442	0.5072	0.3267	0.295545237065	3.8	0.999919	0.712	0.650396906566	0.892	0.699861347675	-3.1	0.602	0.599	0.003	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	N	None
26423	38	V/A	rs576203363	0.1032	gnomAD-4.0.0	40	None	0.6677	0.6217	26.9	D	-2.538	-0.34	0.029284	-2.442	0.5072	0.3267	0.295545237065	3.8	0.999919	0.712	0.650396906566	0.892	0.699861347675	-3.1	0.602	0.599	0.003	None	None	4.95833E-06	0	0	0	0	None	0	0	4.95833E-06	5.08617E-06	2.19611E-05	0	None	N	None
26423	38	V/G	None	0.1032	gnomAD-4.0.0	40	None	0.9246	0.9331	33.0	D	None	-0.37	0.100717	-3.053	0.6436	0.634	0.486715451747	4.145	1.0	0.792	0.851511300201	0.983	0.588538646698	-4.99	0.789	0.861	0.001	None	None	6.8434E-07	0	0	0	0	None	0	0	6.8434E-07	0	0	1.65706E-05	None	N	None
26423	38	V/L	rs1706066147	0.1032	gnomAD-3.1.2	40	None	0.2604	0.2673	23.7	N	None	-0.07	0.018254	-0.671	0.1554	-0.9229	0.0908555217513	0.975	0.998836	0.608	0.288727942641	0.025	0.683749437332	-2.19	0.19	0.347	0.446	None	None	1.97E-05	0	1.96799E-04	0	0	None	0	0	1.97E-05	0	0	0	None	N	None
26423	38	V/L	rs1706066147	0.1032	gnomAD-4.0.0	40	None	0.2604	0.2673	23.7	N	None	-0.07	0.018254	-0.671	0.1554	-0.9229	0.0908555217513	0.975	0.998836	0.608	0.288727942641	0.025	0.683749437332	-2.19	0.19	0.347	0.446	None	None	1.97259E-05	0	1.96799E-04	0	0	None	0	0	1.97259E-05	0	0	0	None	N	None
26424	39	E/A	None	0.1653	gnomAD-4.0.0	41	None	0.9521	0.9468	34.0	D	None	0.33	0.193326	-1.7	0.5846	0.5455	0.476869963243	4.32	1.0	0.559	0.441324992753	0.999	0.733430445194	-4.66	0.603	0.697	0.004	None	None	1.59206E-06	0	0	0	0	None	0	0	1.59206E-06	0	1.43287E-05	0	None	N	None
26424	39	E/K	rs1706064410	0.1653	gnomAD-3.1.2	41	None	0.97	0.9676	33.0	N	None	0.38	0.045341	-1.757	0.4774	0.1156	0.489131336793	3.975	1.0	0.667	0.342400092842	0.999	0.799775242805	-3.2	0.492	0.67	0.004	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
26424	39	E/K	rs1706064410	0.1653	gnomAD-4.0.0	41	None	0.97	0.9676	33.0	N	None	0.38	0.045341	-1.757	0.4774	0.1156	0.489131336793	3.975	1.0	0.667	0.342400092842	0.999	0.799775242805	-3.2	0.492	0.67	0.004	None	None	6.57471E-06	0	0	0	0	None	0	0	6.57471E-06	1.4705E-05	0	0	None	N	None
26425	40	K/E	rs1706063163	0.1831	gnomAD-4.0.0	42	None	0.9831	0.9824	27.5	N	None	0.38	0.041887	-2.036	0.3192	-0.317	0.237924470368	3.405	0.999991	0.605	0.28297238246	0.41	0.709408342838	-2.98	0.446	0.669	0.005	None	None	3.49016E-05	0	0	0	0	None	0	0	3.49016E-05	4.49775E-05	0	1.65706E-05	None	N	None
26425	40	K/I	rs1359744760	0.1831	gnomAD-2.1.1	42	None	0.9752	0.9719	32.0	N	-0.056	0.46	0.047073	-0.011	0.2571	-0.6478	0.518132348203	2.51	0.999976	0.621	0.418718287753	0.908	0.679396927357	-6.1	0.354	0.849	0.001	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
26425	40	K/I	rs1359744760	0.1831	gnomAD-4.0.0	42	None	0.9752	0.9719	32.0	N	-0.056	0.46	0.047073	-0.011	0.2571	-0.6478	0.518132348203	2.51	0.999976	0.621	0.418718287753	0.908	0.679396927357	-6.1	0.354	0.849	0.001	None	None	2.05305E-06	0	0	0	0	None	0	0	2.05305E-06	0	3.47818E-05	0	None	N	None
26426	41	R/I	None	0.2172	gnomAD-4.0.0	43	None	0.9638	0.9572	28.0	D	None	0.29	0.131754	-1.041	0.554	0.4871	0.572056272274	3.865	1.0	0.719	0.596373027241	0.983	0.772979140282	-6.15	0.506	0.797	0.002	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26427	42	D/E	rs766994654	0.1763	gnomAD-2.1.1	44	None	0.7597	0.7094	23.8	N	-0.658	0.55	0.036482	-0.76	0.0838	-1.0583	0.101295607235	0.665	0.999556	0.459	0.239901079897	0.067	0.690876841545	-2.57	0.07	0.272	0.5	None	None	3.22E-05	0	0	0	0	None	0	None	3.22E-05	0	7.06E-05	0	None	N	None
26427	42	D/E	rs766994654	0.1763	gnomAD-3.1.2	44	None	0.7597	0.7094	23.8	N	-0.658	0.55	0.036482	-0.76	0.0838	-1.0583	0.101295607235	0.665	0.999556	0.459	0.239901079897	0.067	0.690876841545	-2.57	0.07	0.272	0.5	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	N	None
26427	42	D/E	rs766994654	0.1763	gnomAD-4.0.0	44	None	0.7597	0.7094	23.8	N	-0.658	0.55	0.036482	-0.76	0.0838	-1.0583	0.101295607235	0.665	0.999556	0.459	0.239901079897	0.067	0.690876841545	-2.57	0.07	0.272	0.5	None	None	6.84363E-07	0	0	0	2.52385E-05	None	0	0	6.84363E-07	0	0	0	None	N	None
26427	42	D/H	rs1157004476	0.1763	gnomAD-3.1.2	44	None	0.9437	0.9307	32.0	N	None	0.39	0.035345	-0.276	0.3955	-0.2046	0.483546923472	3.035	1.0	0.508	0.40417439687	0.998	0.737145781517	-5.05	0.489	0.755	0.098	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
26427	42	D/H	rs1157004476	0.1763	gnomAD-4.0.0	44	None	0.9437	0.9307	32.0	N	None	0.39	0.035345	-0.276	0.3955	-0.2046	0.483546923472	3.035	1.0	0.508	0.40417439687	0.998	0.737145781517	-5.05	0.489	0.755	0.098	None	None	6.57462E-06	2.41348E-05	0	0	0	None	0	0	6.57462E-06	0	0	0	None	N	None
26427	42	D/N	rs1157004476	0.1763	gnomAD-2.1.1	44	None	0.7934	0.7265	31.0	N	None	0.43	0.032554	-1.213	0.3303	-0.4205	0.412108884712	2.73	1.0	0.506	0.342400092842	0.988	0.712101995945	-3.47	0.375	0.645	0.011	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
26427	42	D/N	rs1157004476	0.1763	gnomAD-4.0.0	44	None	0.7934	0.7265	31.0	N	None	0.43	0.032554	-1.213	0.3303	-0.4205	0.412108884712	2.73	1.0	0.506	0.342400092842	0.988	0.712101995945	-3.47	0.375	0.645	0.011	None	None	1.59205E-06	0	0	0	0	None	0	0	1.59205E-06	0	0	3.02554E-05	None	N	None
26429	44	S/N	None	0.6437	gnomAD-4.0.0	54	None	0.1284	0.1034	25.2	N	None	0.56	0.013932	-0.077	0.0797	-0.8902	0.10995767528	-0.125	0.739544	0.366	0.16115917748	0.491	0.593071222305	-2.03	0.092	0.24	0.145	None	None	2.40064E-06	1.26695E-04	0	0	0	None	0	0	2.40064E-06	0	0	0	None	I	None
26429	44	S/R	None	0.6437	gnomAD-4.0.0	54	None	0.6228	0.5124	25.7	N	None	0.42	0.018803	-0.118	0.1009	-1.0357	0.165315284702	0.32	0.996744	0.478	0.216624796971	0.491	0.60298204422	-3.29	0.174	0.278	0.094	None	None	1.59205E-06	0	0	0	0	None	0	0	1.59205E-06	0	1.43283E-05	0	None	I	None
26430	45	G/A	None	0.2691	gnomAD-4.0.0	60	None	0.3968	0.2906	24.6	N	None	0.54	0.041469	-0.295	0.196	-0.6632	0.147539012077	2.22	1.0	0.493	0.256283259241	0.45	0.660655677319	-4.06	0.337	0.505	0.172	None	None	1.20033E-06	0	0	0	0	None	0	0	1.20033E-06	1.31252E-06	0	0	None	N	None
26431	46	I/F	None	1.1568	gnomAD-4.0.0	63	None	0.282	0.2209	26.2	N	None	0.42	0.034302	-0.686	0.2367	-0.6507	0.447973635636	2.155	0.999998	0.408	0.516437024119	0.967	0.693364739418	-3.18	0.229	0.651	0.01	None	None	2.40067E-06	0	0	0	0	None	0	0	2.40067E-06	2.62503E-06	0	0	None	I	None
26431	46	I/N	None	1.1568	gnomAD-4.0.0	63	None	0.5296	0.4496	33.0	N	None	0.56	0.05342	-0.337	0.1967	-0.6512	0.561244684878	0.71	0.999999	0.468	0.72833840645	0.994	0.756688833237	-5.0	0.529	0.668	0.002	None	None	1.59199E-06	0	0	0	0	None	0	0	1.59199E-06	2.85902E-06	0	0	None	I	None
26432	47	R/Q	rs770752765	0.8410	gnomAD-2.1.1	64	None	0.4611	0.4889	27.4	N	-0.024	0.46	0.012156	-0.125	0.3361	-0.4257	0.496624975885	2.1	0.999981	0.552	0.252681307341	1.0	0.621922910213	-2.91	0.35	0.657	0.009	None	None	3.23E-05	0	0	0	0	None	0	None	3.23E-05	0	7.14E-05	0	None	I	None
26432	47	R/Q	rs770752765	0.8410	gnomAD-3.1.2	64	None	0.4611	0.4889	27.4	N	-0.024	0.46	0.012156	-0.125	0.3361	-0.4257	0.496624975885	2.1	0.999981	0.552	0.252681307341	1.0	0.621922910213	-2.91	0.35	0.657	0.009	None	None	1.32E-05	2.41E-05	0	0	0	None	0	0	1.32E-05	0	2.06954E-04	0	None	I	None
26432	47	R/Q	rs770752765	0.8410	gnomAD-4.0.0	64	None	0.4611	0.4889	27.4	N	-0.024	0.46	0.012156	-0.125	0.3361	-0.4257	0.496624975885	2.1	0.999981	0.552	0.252681307341	1.0	0.621922910213	-2.91	0.35	0.657	0.009	None	None	1.54964E-05	1.33558E-05	0	0	0	None	0	1.6442E-04	1.54964E-05	1.86493E-05	1.09786E-05	0	None	I	None
26433	48	W/R	None	0.2114	gnomAD-4.0.0	65	None	0.9995	0.9994	34.0	D	None	0.48	0.272715	-1.089	0.5798	0.6056	0.615612516959	4.81	1.0	0.792	0.758789248963	1.0	0.868267893791	-10.63	0.67	0.723	0.002	None	None	1.59222E-06	0	0	0	2.7784E-05	None	0	0	1.59222E-06	0	0	0	None	N	None
26434	49	I/T	None	0.5463	gnomAD-4.0.0	66	None	0.2393	0.2268	24.9	N	None	0.46	0.012599	-1.149	0.0695	-1.033	0.106484134016	-0.705	0.809333	0.464	0.536661227952	None	0.67752802372	-1.48	0.156	0.181	1.0	None	None	3.18402E-06	0	0	0	2.77809E-05	None	0	0	3.18402E-06	2.85889E-06	0	0	None	I	None
26436	51	C/R	None	0.2383	gnomAD-4.0.0	68	None	0.9904	0.9931	34.0	N	None	0.54	0.048931	-0.688	0.423	0.0311	0.552654234204	3.39	1.0	0.611	0.783465323079	0.97	0.892358183861	-8.79	0.525	0.803	0.004	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26436	51	C/Y	None	0.2383	gnomAD-4.0.0	68	None	0.9533	0.9685	31.0	N	None	0.49	0.053584	-0.915	0.3727	-0.1259	0.53903598711	3.39	0.999999	0.482	0.661029647469	0.97	0.898394584656	-8.1	0.546	0.777	0.002	None	None	2.7375E-06	0	0	0	0	None	0	1.7343E-04	2.7375E-06	0	1.15937E-05	3.31422E-05	None	N	None
26439	54	R/C	rs372968732	0.9190	gnomAD-2.1.1	72	None	0.3357	0.3503	None	N	-0.342	None	None	-0.245	None	None	None	None	None	None	None	1.0	None	None	0.376	0.584	None	None	None	2.82E-05	6.47E-05	8.71E-05	0	0	None	0	None	2.82E-05	0	2.67E-05	0	None	I	None
26439	54	R/C	rs372968732	0.9190	gnomAD-3.1.2	72	None	0.3357	0.3503	None	N	-0.342	None	None	-0.245	None	None	None	None	None	None	None	1.0	None	None	0.376	0.584	None	None	None	2.63E-05	7.24E-05	0	0	0	None	0	0	2.63E-05	1.47E-05	0	0	None	I	None
26439	54	R/C	rs372968732	0.9190	gnomAD-4.0.0	72	None	0.3357	0.3503	None	N	-0.342	None	None	-0.245	None	None	None	None	None	None	None	1.0	None	None	0.376	0.584	None	None	None	2.9755E-05	9.34879E-05	5.0045E-05	0	0	None	0	0	2.9755E-05	3.13652E-05	0	1.60159E-05	None	I	None
26439	54	R/H	rs187941835	0.9190	gnomAD-2.1.1	72	None	0.1723	0.2425	None	N	-0.558	None	None	-0.571	None	None	None	None	None	None	None	0.159	None	None	0.111	0.273	None	None	None	1.61E-05	0	2.9E-05	0	1.11919E-04	None	3.27E-05	None	1.61E-05	0	0	0	None	I	None
26439	54	R/H	rs187941835	0.9190	gnomAD-3.1.2	72	None	0.1723	0.2425	None	N	-0.558	None	None	-0.571	None	None	None	None	None	None	None	0.159	None	None	0.111	0.273	None	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	I	None
26439	54	R/H	rs187941835	0.9190	1000 genomes	72	None	0.1723	0.2425	None	N	-0.558	None	None	-0.571	None	None	None	None	None	None	None	0.159	None	None	0.111	0.273	None	None	None	1.99681E-04	0	0	None	0	1E-03	None	None	1.99681E-04	None	0	None	None	I	None
26439	54	R/H	rs187941835	0.9190	gnomAD-4.0.0	72	None	0.1723	0.2425	None	N	-0.558	None	None	-0.571	None	None	None	None	None	None	None	0.159	None	None	0.111	0.273	None	None	None	3.40917E-05	0	5.00334E-05	0	4.46608E-05	None	3.13519E-05	0	3.40917E-05	3.98422E-05	1.09806E-05	0	None	I	None
26440	55	R/C	rs55861600	0.6627	gnomAD-2.1.1	75	None	0.1737	0.1833	None	D	-0.487	None	None	-0.277	None	None	None	None	None	None	None	0.997	None	None	0.331	0.683	None	None	None	2.51621E-03	2.60348E-02	1.38795E-03	0	0	None	2.61489E-04	None	2.51621E-03	0	8.61E-05	8.43645E-04	None	N	None
26440	55	R/C	rs55861600	0.6627	gnomAD-3.1.2	75	None	0.1737	0.1833	None	D	-0.487	None	None	-0.277	None	None	None	None	None	None	None	0.997	None	None	0.331	0.683	None	None	None	7.51355E-03	2.59991E-02	2.62398E-03	0	0	None	0	3.16456E-03	7.51355E-03	1.47098E-04	4.14938E-04	6.20821E-03	None	N	None
26440	55	R/C	rs55861600	0.6627	1000 genomes	75	None	0.1737	0.1833	None	D	-0.487	None	None	-0.277	None	None	None	None	None	None	None	0.997	None	None	0.331	0.683	None	None	None	6.58946E-03	2.19E-02	4.3E-03	None	1E-03	0	None	None	6.58946E-03	None	0	None	None	N	None
26440	55	R/C	rs55861600	0.6627	gnomAD-4.0.0	75	None	0.1737	0.1833	None	D	-0.487	None	None	-0.277	None	None	None	None	None	None	None	0.997	None	None	0.331	0.683	None	None	None	1.471E-03	2.69217E-02	1.7844E-03	0	4.46708E-05	None	0	1.1555E-03	1.471E-03	7.54471E-05	2.08635E-04	2.09728E-03	None	N	None
26440	55	R/H	rs56044609	0.6627	gnomAD-2.1.1	75	None	0.1201	0.1184	None	N	-1.351	None	None	-0.688	None	None	None	None	None	None	None	0.096	None	None	0.102	0.243	None	None	None	1.76438E-03	1.59315E-02	1.58595E-03	0	0	None	5.22944E-04	None	1.76438E-03	8.08E-05	1.80087E-04	1.54625E-03	None	N	None
26440	55	R/H	rs56044609	0.6627	gnomAD-3.1.2	75	None	0.1201	0.1184	None	N	-1.351	None	None	-0.688	None	None	None	None	None	None	None	0.096	None	None	0.102	0.243	None	None	None	5.02513E-03	1.66127E-02	2.69064E-03	0	0	None	0	9.49367E-03	5.02513E-03	2.20614E-04	1.03648E-03	5.73066E-03	None	N	None
26440	55	R/H	rs56044609	0.6627	1000 genomes	75	None	0.1201	0.1184	None	N	-1.351	None	None	-0.688	None	None	None	None	None	None	None	0.096	None	None	0.102	0.243	None	None	None	4.59265E-03	1.74E-02	0	None	0	0	None	None	4.59265E-03	None	0	None	None	N	None
26440	55	R/H	rs56044609	0.6627	gnomAD-4.0.0	75	None	0.1201	0.1184	None	N	-1.351	None	None	-0.688	None	None	None	None	None	None	None	0.096	None	None	0.102	0.243	None	None	None	1.05004E-03	1.68031E-02	2.08479E-03	0	4.46488E-05	None	4.70544E-05	2.64026E-03	1.05004E-03	9.32463E-05	6.47825E-04	1.9051E-03	None	N	None
26440	55	R/L	rs56044609	0.6627	gnomAD-3.1.2	75	None	0.2142	0.2271	24.3	N	None	0.31	0.035657	0.412	0.1358	-0.8812	0.267997039011	0.39	0.997353	0.587	0.415313616471	0.768	0.653024315834	-4.61	0.33	0.59	0.211	None	None	6.58E-06	0	0	0	0	None	9.42E-05	0	6.58E-06	0	0	0	None	N	None
26440	55	R/L	rs56044609	0.6627	gnomAD-4.0.0	75	None	0.2142	0.2271	24.3	N	None	0.31	0.035657	0.412	0.1358	-0.8812	0.267997039011	0.39	0.997353	0.587	0.415313616471	0.768	0.653024315834	-4.61	0.33	0.59	0.211	None	None	6.5773E-06	0	0	0	0	None	9.42152E-05	0	6.5773E-06	0	0	0	None	N	None
26441	56	I/V	rs1305096924	0.1812	gnomAD-3.1.2	77	None	0.0804	0.0797	23.0	N	None	0.51	0.011496	-0.965	0.0681	-1.0601	0.0704899027279	-0.36	0.901491	0.443	0.303123707472	0.001	0.601680159569	-0.33	0.04	0.167	0.5	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
26441	56	I/V	rs1305096924	0.1812	gnomAD-4.0.0	77	None	0.0804	0.0797	23.0	N	None	0.51	0.011496	-0.965	0.0681	-1.0601	0.0704899027279	-0.36	0.901491	0.443	0.303123707472	0.001	0.601680159569	-0.33	0.04	0.167	0.5	None	None	6.57341E-06	0	0	0	0	None	0	0	6.57341E-06	1.47037E-05	0	0	None	N	None
26442	57	T/I	rs1288656149	0.6375	gnomAD-2.1.1	83	None	0.3186	0.4479	33.0	N	0.028	0.19	0.030857	-0.182	0.4247	-0.1473	0.456294190807	2.585	1.0	0.501	0.509762279564	0.994	0.833472728729	-4.6	0.51	0.684	0.015	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	I	None
26442	57	T/I	rs1288656149	0.6375	gnomAD-3.1.2	83	None	0.3186	0.4479	33.0	N	0.028	0.19	0.030857	-0.182	0.4247	-0.1473	0.456294190807	2.585	1.0	0.501	0.509762279564	0.994	0.833472728729	-4.6	0.51	0.684	0.015	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	0	2.06868E-04	0	None	I	None
26442	57	T/I	rs1288656149	0.6375	gnomAD-4.0.0	83	None	0.3186	0.4479	33.0	N	0.028	0.19	0.030857	-0.182	0.4247	-0.1473	0.456294190807	2.585	1.0	0.501	0.509762279564	0.994	0.833472728729	-4.6	0.51	0.684	0.015	None	None	2.56379E-06	0	0	0	0	None	0	0	2.56379E-06	0	2.67996E-05	0	None	I	None
26442	57	T/R	None	0.6375	gnomAD-4.0.0	83	None	0.3699	0.5275	33.0	N	None	0.23	0.025457	-0.063	0.308	-0.4753	0.469336316903	1.565	1.0	0.566	0.584086171949	0.994	0.80622625351	-4.19	0.457	0.684	0.124	None	None	1.59234E-06	0	0	0	2.77747E-05	None	0	0	1.59234E-06	0	0	0	None	I	None
26445	60	R/C	rs780658084	0.6755	gnomAD-2.1.1	90	None	0.6118	0.7134	None	N	-0.668	None	None	-0.352	None	None	None	None	None	None	None	1.0	None	None	0.384	0.777	None	None	None	8.06E-06	0	2.9E-05	0	0	None	3.27E-05	None	8.06E-06	0	0	0	None	N	None
26445	60	R/C	rs780658084	0.6755	gnomAD-4.0.0	90	None	0.6118	0.7134	None	N	-0.668	None	None	-0.352	None	None	None	None	None	None	None	1.0	None	None	0.384	0.777	None	None	None	7.52881E-06	0	4.47327E-05	0	0	None	1.88416E-05	0	7.52881E-06	1.79907E-06	3.47834E-05	4.97117E-05	None	N	None
26445	60	R/H	rs764254441	0.6755	gnomAD-2.1.1	90	None	0.4146	0.5451	None	N	-1.446	None	None	-1.015	None	None	None	None	None	None	None	1.0	None	None	0.342	0.771	None	None	None	5.01E-05	8.27E-05	5.66E-05	0	0	None	3.27E-05	None	5.01E-05	0	7.05E-05	0	None	N	None
26445	60	R/H	rs764254441	0.6755	gnomAD-3.1.2	90	None	0.4146	0.5451	None	N	-1.446	None	None	-1.015	None	None	None	None	None	None	None	1.0	None	None	0.342	0.771	None	None	None	8.55E-05	0	6.55E-05	0	1.93874E-04	None	0	0	8.55E-05	1.61774E-04	0	0	None	N	None
26445	60	R/H	rs764254441	0.6755	gnomAD-4.0.0	90	None	0.4146	0.5451	None	N	-1.446	None	None	-1.015	None	None	None	None	None	None	None	1.0	None	None	0.342	0.771	None	None	None	7.19055E-05	4.00502E-05	5.00283E-05	0	8.92817E-05	None	0	1.64474E-04	7.19055E-05	8.05303E-05	6.58747E-05	6.40594E-05	None	N	None
26445	60	R/L	None	0.6755	gnomAD-4.0.0	90	None	0.8697	0.9239	32.0	N	None	0.33	0.019683	0.476	0.4717	0.0008	0.516030974754	2.55	0.999992	0.629	0.674874776785	1.0	0.814013898373	-4.57	0.386	0.658	0.047	None	None	6.84406E-07	0	0	0	0	None	0	0	6.84406E-07	8.99536E-07	0	0	None	N	None
26445	60	R/S	rs780658084	0.6755	gnomAD-2.1.1	90	None	0.9656	0.9785	32.0	N	-1.025	0.58	0.014	-0.54	0.2679	-0.5872	0.491463298746	0.46	0.999158	0.561	0.379193981924	1.0	0.803862690926	-3.65	0.268	0.732	0.28	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
26445	60	R/S	rs780658084	0.6755	gnomAD-4.0.0	90	None	0.9656	0.9785	32.0	N	-1.025	0.58	0.014	-0.54	0.2679	-0.5872	0.491463298746	0.46	0.999158	0.561	0.379193981924	1.0	0.803862690926	-3.65	0.268	0.732	0.28	None	None	6.84437E-07	0	0	0	0	None	0	0	6.84437E-07	8.99533E-07	0	0	None	N	None
26446	61	L/I	None	0.1916	gnomAD-4.0.0	91	None	0.148	0.1487	23.0	N	None	0.36	0.015245	-0.617	0.1336	-0.9583	0.108664449651	0.785	0.918691	0.498	0.165133752707	0.811	0.752830266953	-1.15	0.091	0.52	0.165	None	None	6.84399E-07	0	0	0	0	None	0	0	6.84399E-07	0	1.15942E-05	0	None	N	None
26446	61	L/V	None	0.1916	gnomAD-4.0.0	91	None	0.143	0.1481	23.0	N	None	0.58	0.016283	-1.014	0.1065	-0.9858	0.101341896359	0.645	0.869913	0.483	0.165133752707	0.896	0.718347191811	-1.91	0.087	0.521	0.116	None	None	6.84399E-07	0	0	0	2.5227E-05	None	0	0	6.84399E-07	0	0	0	None	N	None
26447	62	R/G	None	0.6211	gnomAD-4.0.0	92	None	0.9475	0.9582	24.9	N	None	0.39	0.028354	-0.747	0.3013	-0.4081	0.382302591889	2.77	0.999816	0.591	0.539567288477	0.892	0.795078754425	-5.21	0.358	0.637	0.008	None	None	1.59217E-06	0	0	0	2.77624E-05	None	0	0	1.59217E-06	0	0	0	None	N	None
26447	62	R/K	None	0.6211	gnomAD-4.0.0	92	None	0.2812	0.3321	25.3	N	None	0.48	0.013856	-0.515	0.1108	-0.997	0.093438862055	0.17	0.999855	0.453	0.202086224978	0.025	0.837249279022	-2.11	0.143	0.308	0.243	None	None	4.77661E-06	0	0	0	0	None	0	0	4.77661E-06	5.71762E-06	0	3.02572E-05	None	N	None
26448	63	V/G	rs1553590427	0.1404	gnomAD-4.0.0	93	None	0.8966	0.9095	33.0	D	None	0.05	0.079507	-2.413	0.6096	0.5543	0.527292994097	4.425	1.0	0.752	0.928233509922	1.0	0.830471932888	-4.91	0.702	0.79	None	None	None	3.42193E-06	0	0	0	0	None	0	0	3.42193E-06	4.49762E-06	0	0	None	N	None
26448	63	V/M	rs1380054566	0.1404	gnomAD-2.1.1	93	None	0.6635	0.6684	29.4	D	-0.519	0.07	0.03022	-0.578	0.5558	0.3444	0.465052223951	3.62	1.0	0.464	0.532311620844	1.0	0.888044536114	-2.14	0.38	0.687	0.078	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.67E-05	0	None	N	None
26448	63	V/M	rs1380054566	0.1404	gnomAD-3.1.2	93	None	0.6635	0.6684	29.4	D	-0.519	0.07	0.03022	-0.578	0.5558	0.3444	0.465052223951	3.62	1.0	0.464	0.532311620844	1.0	0.888044536114	-2.14	0.38	0.687	0.078	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
26448	63	V/M	rs1380054566	0.1404	gnomAD-4.0.0	93	None	0.6635	0.6684	29.4	D	-0.519	0.07	0.03022	-0.578	0.5558	0.3444	0.465052223951	3.62	1.0	0.464	0.532311620844	1.0	0.888044536114	-2.14	0.38	0.687	0.078	None	None	2.85135E-05	0	0	0	0	None	0	0	2.85135E-05	3.8993E-05	0	0	None	N	None
26450	65	G/R	rs752326213	0.4602	gnomAD-2.1.1	96	None	0.9154	0.8823	27.4	N	-0.117	0.06	0.082509	-0.345	0.4817	-0.0012	0.476211014082	2.565	1.0	0.669	0.700708160949	0.997	0.92305970192	-5.76	0.527	0.763	0.046	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
26450	65	G/R	rs752326213	0.4602	gnomAD-3.1.2	96	None	0.9154	0.8823	27.4	N	-0.117	0.06	0.082509	-0.345	0.4817	-0.0012	0.476211014082	2.565	1.0	0.669	0.700708160949	0.997	0.92305970192	-5.76	0.527	0.763	0.046	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
26450	65	G/R	rs752326213	0.4602	gnomAD-4.0.0	96	None	0.9154	0.8823	27.4	N	-0.117	0.06	0.082509	-0.345	0.4817	-0.0012	0.476211014082	2.565	1.0	0.669	0.700708160949	0.997	0.92305970192	-5.76	0.527	0.763	0.046	None	None	5.12723E-06	1.69165E-05	0	0	0	None	0	0	5.12723E-06	7.18095E-06	0	0	None	N	None
26452	67	T/K	rs375061238	0.3868	gnomAD-3.1.2	98	None	0.4455	0.4517	None	N	None	None	None	-0.841	None	None	None	None	None	None	None	0.999	None	None	0.503	0.592	None	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
26452	67	T/K	rs375061238	0.3868	gnomAD-4.0.0	98	None	0.4455	0.4517	None	N	None	None	None	-0.841	None	None	None	None	None	None	None	0.999	None	None	0.503	0.592	None	None	None	6.57618E-06	2.41359E-05	0	0	0	None	0	0	6.57618E-06	0	0	0	None	N	None
26453	68	E/D	rs1299909025	0.4584	gnomAD-2.1.1	99	None	0.3389	0.2734	28.0	N	-0.516	0.33	0.019052	-0.83	0.3832	-0.2682	0.442122350618	3.035	0.993308	0.473	0.301455362545	0.999	0.818432807922	-2.1	0.316	0.552	0.028	None	None	4.03E-06	0	0	0	5.58E-05	None	0	None	4.03E-06	0	0	0	None	N	None
26453	68	E/D	rs1299909025	0.4584	gnomAD-4.0.0	99	None	0.3389	0.2734	28.0	N	-0.516	0.33	0.019052	-0.83	0.3832	-0.2682	0.442122350618	3.035	0.993308	0.473	0.301455362545	0.999	0.818432807922	-2.1	0.316	0.552	0.028	None	None	1.59214E-06	0	0	0	2.77608E-05	None	0	0	1.59214E-06	0	0	0	None	N	None
26453	68	E/K	None	0.4584	gnomAD-4.0.0	99	None	0.3112	0.2497	27.0	N	None	0.37	0.021112	-0.123	0.4131	-0.1373	0.489131336793	2.88	1.0	0.635	0.483224754729	0.999	0.866120815277	-3.08	0.385	0.666	0.011	None	None	1.59227E-06	0	0	0	0	None	0	0	1.59227E-06	2.85889E-06	0	0	None	N	None
26453	68	E/V	None	0.4584	gnomAD-4.0.0	99	None	0.3992	0.3157	35.0	N	None	0.33	0.036228	0.008	0.4469	0.011	0.500354548257	3.085	0.999999	0.673	0.652849316004	1.0	0.811891615391	-4.65	0.513	0.669	0.003	None	None	1.59213E-06	5.65867E-05	0	0	0	None	0	0	1.59213E-06	0	0	0	None	N	None
26454	69	D/Y	None	0.5943	gnomAD-4.0.0	100	None	0.2141	0.2363	31.0	N	None	0.39	0.02754	-0.29	0.3159	-0.4681	0.514144971276	1.34	1.0	0.585	0.594593949059	1.0	0.847771167755	-6.13	0.507	0.884	0.016	None	None	1.59213E-06	0	0	0	0	None	0	0	1.59213E-06	0	1.43283E-05	0	None	N	None
26455	70	H/L	rs1706027095	0.3676	gnomAD-4.0.0	102	None	0.5956	0.55	33.0	N	None	0.45	0.03892	0.517	0.3156	-0.4213	0.514590015321	1.855	1.0	0.496	0.583959843308	1.0	0.858833193779	-7.53	0.473	0.751	0.311	None	None	2.05314E-06	0	0	0	0	None	0	0	2.05314E-06	2.69865E-06	0	0	None	N	None
26455	70	H/Y	None	0.3676	gnomAD-4.0.0	102	None	0.4193	0.374	34.0	N	None	0.42	0.01608	0.909	0.3846	-0.2642	0.496624975885	2.64	1.0	0.504	0.330331372229	0.999	0.873996973038	-3.85	0.522	0.606	0.425	None	None	6.84394E-07	0	0	0	0	None	0	0	6.84394E-07	8.9953E-07	0	0	None	N	None
26456	71	E/A	rs767070836	0.2683	gnomAD-2.1.1	103	None	0.2539	0.232	35.0	N	-1.446	0.32	0.043091	-1.048	0.378	-0.2083	0.387601023604	2.39	0.999999	0.553	0.479518371956	0.994	0.852089345455	-4.63	0.535	0.561	0.051	None	None	1.21E-05	0	0	0	0	None	9.81E-05	None	1.21E-05	0	0	0	None	N	None
26456	71	E/A	rs767070836	0.2683	gnomAD-4.0.0	103	None	0.2539	0.232	35.0	N	-1.446	0.32	0.043091	-1.048	0.378	-0.2083	0.387601023604	2.39	0.999999	0.553	0.479518371956	0.994	0.852089345455	-4.63	0.535	0.561	0.051	None	None	1.11453E-05	0	0	0	0	None	0	0	1.11453E-05	0	1.00301E-04	0	None	N	None
26456	71	E/K	rs1706025148	0.2683	gnomAD-3.1.2	103	None	0.439	0.4311	34.0	N	None	0.4	0.040665	-1.143	0.3275	-0.4261	0.375299811977	2.22	0.999999	0.659	0.4018988957	0.989	0.893556833267	-3.05	0.334	0.462	0.042	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
26456	71	E/K	rs1706025148	0.2683	gnomAD-4.0.0	103	None	0.439	0.4311	34.0	N	None	0.4	0.040665	-1.143	0.3275	-0.4261	0.375299811977	2.22	0.999999	0.659	0.4018988957	0.989	0.893556833267	-3.05	0.334	0.462	0.042	None	None	1.5225E-05	6.98983E-05	0	0	0	None	0	0	1.5225E-05	1.32544E-05	0	0	None	N	None
26458	73	E/D	rs1162274016	0.0786	gnomAD-2.1.1	105	None	0.8688	0.8641	23.7	N	-1.475	0.27	0.056863	-1.566	0.3167	-0.4318	0.295431489209	3.165	0.999045	0.373	0.210429274316	0.958	0.855473637581	-2.14	0.303	0.598	0.066	None	None	4.03E-06	0	0	0	5.58E-05	None	0	None	4.03E-06	0	0	0	None	N	None
26458	73	E/D	rs1162274016	0.0786	gnomAD-4.0.0	105	None	0.8688	0.8641	23.7	N	-1.475	0.27	0.056863	-1.566	0.3167	-0.4318	0.295431489209	3.165	0.999045	0.373	0.210429274316	0.958	0.855473637581	-2.14	0.303	0.598	0.066	None	None	1.59216E-06	0	0	0	2.77546E-05	None	0	0	1.59216E-06	0	0	0	None	N	None
26459	74	F/C	None	0.1203	gnomAD-4.0.0	106	None	0.9815	0.9798	35.0	D	None	0.06	0.162225	-1.639	0.617	0.5272	0.53220533833	4.72	0.999968	0.627	0.633181949713	0.999	0.909467101097	-5.7	0.515	0.845	None	None	None	2.73749E-06	0	0	0	0	None	0	0	2.73749E-06	3.59813E-06	0	0	None	N	None
26460	75	R/G	rs1406730761	0.1531	gnomAD-2.1.1	107	None	0.9615	0.9534	34.0	D	-2.326	0.16	0.147293	-2.153	0.5713	0.3706	0.450788619481	4.76	0.999936	0.674	0.355034743287	0.994	0.765375733376	-5.44	0.507	0.587	None	None	None	4.03E-06	0	0	0	5.58E-05	None	0	None	4.03E-06	0	0	0	None	I	None
26460	75	R/G	rs1406730761	0.1531	gnomAD-4.0.0	107	None	0.9615	0.9534	34.0	D	-2.326	0.16	0.147293	-2.153	0.5713	0.3706	0.450788619481	4.76	0.999936	0.674	0.355034743287	0.994	0.765375733376	-5.44	0.507	0.587	None	None	None	1.36876E-06	0	0	0	5.04261E-05	None	0	0	1.36876E-06	0	0	0	None	I	None
26460	75	R/K	None	0.1531	gnomAD-4.0.0	107	None	0.4336	0.3626	25.2	N	None	0.27	0.034708	-1.348	0.2993	-0.3334	0.112338637192	2.965	0.999898	0.681	0.257786959452	0.543	0.809277415276	-2.23	0.356	0.314	None	None	None	2.40064E-06	0	0	1.94099E-04	0	None	0	0	2.40064E-06	0	0	3.66327E-05	None	I	None
26461	76	V/A	rs1351446352	0.0740	gnomAD-2.1.1	108	None	0.6289	0.6915	29.5	D	-2.676	-0.8	0.063289	-2.571	0.5876	0.463	0.295545237065	3.61	0.999944	0.842	0.693223118719	0.939	0.76738345623	-2.9	0.739	0.564	0.041	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.48E-05	0	None	N	None
26461	76	V/A	rs1351446352	0.0740	gnomAD-3.1.2	108	None	0.6289	0.6915	29.5	D	-2.676	-0.8	0.063289	-2.571	0.5876	0.463	0.295545237065	3.61	0.999944	0.842	0.693223118719	0.939	0.76738345623	-2.9	0.739	0.564	0.041	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
26461	76	V/A	rs1351446352	0.0740	gnomAD-4.0.0	108	None	0.6289	0.6915	29.5	D	-2.676	-0.8	0.063289	-2.571	0.5876	0.463	0.295545237065	3.61	0.999944	0.842	0.693223118719	0.939	0.76738345623	-2.9	0.739	0.564	0.041	None	None	6.57808E-06	0	0	0	0	None	0	0	6.57808E-06	1.47102E-05	0	0	None	N	None
26461	76	V/I	None	0.0740	gnomAD-4.0.0	108	None	0.115	0.1135	25.7	D	None	-0.51	0.026947	-0.931	0.3399	-0.337	0.203420915256	1.68	0.998407	0.796	0.458013479912	0.76	0.629498839378	-0.67	0.248	0.512	0.078	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26462	77	S/P	None	0.1279	gnomAD-4.0.0	109	None	0.9892	0.9923	33.0	N	None	0.39	0.03582	-0.736	0.3943	-0.0925	0.460658693691	3.405	0.999981	0.452	0.386721274199	0.983	0.81033885479	-3.69	0.468	0.717	0.034	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26463	78	A/G	None	0.0959	gnomAD-4.0.0	110	None	0.6334	0.6866	34.0	D	None	-0.99	0.081975	-2.211	0.6897	0.5522	0.464868906428	3.71	1.0	0.875	0.670813272841	1.0	0.792898833752	-3.21	0.728	0.621	None	None	None	3.42197E-06	0	0	0	0	None	0	0	3.42197E-06	4.49767E-06	0	0	None	N	None
26464	79	E/A	rs766335027	0.2429	gnomAD-2.1.1	111	None	0.75	0.7422	34.0	N	-1.384	0.48	0.049649	-1.449	0.3705	-0.2171	0.476869963243	2.475	1.0	0.446	0.362960570912	0.999	0.838638305664	-5.08	0.558	0.663	0.041	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
26464	79	E/A	rs766335027	0.2429	gnomAD-4.0.0	111	None	0.75	0.7422	34.0	N	-1.384	0.48	0.049649	-1.449	0.3705	-0.2171	0.476869963243	2.475	1.0	0.446	0.362960570912	0.999	0.838638305664	-5.08	0.558	0.663	0.041	None	None	3.18427E-06	0	0	0	0	None	0	0	3.18427E-06	5.71785E-06	0	0	None	N	None
26464	79	E/D	None	0.2429	gnomAD-4.0.0	111	None	0.8296	0.8491	27.9	N	None	0.4	0.024366	-1.356	0.4285	-0.0249	0.442122350618	3.445	0.999798	0.409	0.350088858571	0.999	0.837626457214	-2.32	0.299	0.476	0.073	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26464	79	E/G	rs766335027	0.2429	gnomAD-2.1.1	111	None	0.8761	0.8644	34.0	N	-1.897	0.4	0.064866	-1.838	0.4312	0.0328	0.500420847697	3.165	1.0	0.437	0.450248222533	1.0	0.811865329742	-5.87	0.541	0.753	0.013	None	None	8.06E-06	0	0	0	0	None	6.54E-05	None	8.06E-06	0	0	0	None	N	None
26464	79	E/G	rs766335027	0.2429	gnomAD-4.0.0	111	None	0.8761	0.8644	34.0	N	-1.897	0.4	0.064866	-1.838	0.4312	0.0328	0.500420847697	3.165	1.0	0.437	0.450248222533	1.0	0.811865329742	-5.87	0.541	0.753	0.013	None	None	4.7764E-06	0	0	0	0	None	0	0	4.7764E-06	0	4.29861E-05	0	None	N	None
26466	81	A/G	rs762829887	0.6146	gnomAD-2.1.1	113	None	0.2615	0.2895	28.9	N	-0.197	0.65	0.029093	-0.27	0.169	-0.8304	0.088512119463	2.465	0.999465	0.413	0.274366138417	0.014	0.75789809227	-3.09	0.129	0.302	0.072	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	I	None
26466	81	A/G	rs762829887	0.6146	gnomAD-3.1.2	113	None	0.2615	0.2895	28.9	N	-0.197	0.65	0.029093	-0.27	0.169	-0.8304	0.088512119463	2.465	0.999465	0.413	0.274366138417	0.014	0.75789809227	-3.09	0.129	0.302	0.072	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	I	None
26466	81	A/G	rs762829887	0.6146	gnomAD-4.0.0	113	None	0.2615	0.2895	28.9	N	-0.197	0.65	0.029093	-0.27	0.169	-0.8304	0.088512119463	2.465	0.999465	0.413	0.274366138417	0.014	0.75789809227	-3.09	0.129	0.302	0.072	None	None	8.67826E-06	0	0	0	0	None	0	0	8.67826E-06	1.10199E-05	0	1.60154E-05	None	I	None
26467	82	A/S	rs773008593	0.4975	gnomAD-2.1.1	114	None	0.2655	0.2782	25.7	N	-0.319	0.34	0.022244	-0.595	0.3124	-0.4269	0.355039378975	2.035	0.999978	0.435	0.292423486923	0.979	0.719089984894	-2.07	0.247	0.635	0.119	None	None	1.61E-05	0	0	0	0	None	1.30762E-04	None	1.61E-05	0	0	0	None	I	None
26467	82	A/S	rs773008593	0.4975	gnomAD-4.0.0	114	None	0.2655	0.2782	25.7	N	-0.319	0.34	0.022244	-0.595	0.3124	-0.4269	0.355039378975	2.035	0.999978	0.435	0.292423486923	0.979	0.719089984894	-2.07	0.247	0.635	0.119	None	None	8.8968E-06	0	0	0	0	None	0	0	8.8968E-06	0	1.50725E-04	0	None	I	None
26467	82	A/T	None	0.4975	gnomAD-4.0.0	114	None	0.5445	0.5819	26.3	N	None	0.34	0.025418	-0.677	0.3335	-0.3072	0.340885797724	3.37	0.999991	0.511	0.322230723748	0.958	0.748379468918	-2.39	0.35	0.739	0.007	None	None	2.05311E-06	0	0	0	0	None	0	0	2.05311E-06	0	3.47826E-05	0	None	I	None
26469	84	V/A	None	0.4015	gnomAD-4.0.0	117	None	0.1352	0.1458	28.4	N	None	0.59	0.028153	-1.147	0.1665	-0.784	0.14885761292	2.08	0.995441	0.342	0.416075642716	0.517	0.566351592541	-2.99	0.217	0.585	0.012	None	None	1.592E-06	0	0	0	0	None	0	0	1.592E-06	0	0	3.02572E-05	None	N	None
26469	84	V/I	rs540254651	0.4015	gnomAD-3.1.2	117	None	0.0604	0.0613	21.8	N	-0.707	0.59	0.00944	-0.667	0.0958	-0.9584	0.07008355969	0.825	0.731957	0.342	0.176091768786	0.003	0.407311141491	-0.66	0.022	0.243	0.402	None	None	1.31E-05	4.82E-05	0	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
26469	84	V/I	rs540254651	0.4015	1000 genomes	117	None	0.0604	0.0613	21.8	N	-0.707	0.59	0.00944	-0.667	0.0958	-0.9584	0.07008355969	0.825	0.731957	0.342	0.176091768786	0.003	0.407311141491	-0.66	0.022	0.243	0.402	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	N	None
26469	84	V/I	rs540254651	0.4015	gnomAD-4.0.0	117	None	0.0604	0.0613	21.8	N	-0.707	0.59	0.00944	-0.667	0.0958	-0.9584	0.07008355969	0.825	0.731957	0.342	0.176091768786	0.003	0.407311141491	-0.66	0.022	0.243	0.402	None	None	8.11889E-06	3.48663E-05	0	0	0	None	0	0	8.11889E-06	7.22972E-06	0	0	None	N	None
26471	86	E/G	None	0.7991	gnomAD-4.0.0	119	None	0.1561	0.1704	29.1	N	None	0.42	0.0501	-0.69	0.274	-0.3216	0.258682415415	3.015	0.98727	0.49	0.363158594168	0.92	0.482203483582	-4.95	0.341	0.509	0.008	None	None	1.59201E-06	0	0	0	0	None	0	0	1.59201E-06	0	0	3.02572E-05	None	I	None
26471	86	E/K	None	0.7991	gnomAD-4.0.0	119	None	0.1181	0.1354	23.9	D	None	0.39	0.075792	0.228	0.205	-0.6489	0.212781491612	1.19	0.991563	0.554	0.264547087235	0.704	0.597081243992	-2.55	0.204	0.441	0.179	None	None	3.60099E-06	0	0	0	0	None	0	0	3.60099E-06	3.93751E-06	0	0	None	I	None
26473	88	S/G	None	0.1201	gnomAD-4.0.0	121	None	0.2523	0.2915	27.8	D	None	-0.51	0.036911	-1.038	0.6237	0.462	0.443632335628	3.595	0.999999	0.604	0.469907520169	0.999	0.548009037971	-3.03	0.686	0.882	None	None	None	1.20032E-06	0	0	0	2.75482E-04	None	0	0	1.20032E-06	0	0	0	None	N	None
26473	88	S/N	None	0.1201	gnomAD-4.0.0	121	None	0.851	0.8423	32.0	D	None	-0.54	0.101818	-1.012	0.7454	0.8317	0.448649923726	4.145	1.0	0.61	0.503744809241	0.999	0.632458269596	-2.31	0.538	0.889	None	None	None	6.84346E-07	0	0	0	0	None	0	0	6.84346E-07	8.99543E-07	0	0	None	N	None
26474	89	P/A	rs761511285	0.7285	gnomAD-2.1.1	122	None	0.051	0.0496	25.6	N	-0.277	0.59	0.026663	-0.582	0.1436	-0.9419	0.0886726636444	0.49	0.992976	0.349	0.207176502487	0.044	0.43943965435	-4.45	0.227	0.383	0.191	None	None	8.06E-06	0	0	0	0	None	0	None	8.06E-06	0	1.78E-05	0	None	I	None
26474	89	P/A	rs761511285	0.7285	gnomAD-4.0.0	122	None	0.051	0.0496	25.6	N	-0.277	0.59	0.026663	-0.582	0.1436	-0.9419	0.0886726636444	0.49	0.992976	0.349	0.207176502487	0.044	0.43943965435	-4.45	0.227	0.383	0.191	None	None	1.23184E-05	5.97764E-05	0	0	0	None	0	0	1.23184E-05	1.43926E-05	0	0	None	I	None
26475	90	A/G	rs1706007740	0.3006	gnomAD-4.0.0	123	None	0.1646	0.1477	25.4	N	None	0.54	0.027531	-0.742	0.2122	-0.5326	0.0873899688673	2.39	0.519103	0.303	0.315609569513	0.094	0.464515328407	-2.52	0.206	0.298	0.107	None	None	1.59212E-06	0	0	0	2.77346E-05	None	0	0	1.59212E-06	0	0	0	None	I	None
26475	90	A/P	rs1245328296	0.3006	gnomAD-2.1.1	123	None	0.0795	0.0855	23.6	N	0.013	0.72	0.010384	-0.275	0.0499	-1.0426	0.109202825747	-0.775	0.582163	0.39	0.156986980423	None	0.528678774834	-2.21	0.2	0.178	0.37	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	I	None
26475	90	A/P	rs1245328296	0.3006	gnomAD-4.0.0	123	None	0.0795	0.0855	23.6	N	0.013	0.72	0.010384	-0.275	0.0499	-1.0426	0.109202825747	-0.775	0.582163	0.39	0.156986980423	None	0.528678774834	-2.21	0.2	0.178	0.37	None	None	1.3687E-06	0	0	0	0	None	0	0	1.3687E-06	8.99536E-07	1.15945E-05	0	None	I	None
26476	91	T/I	rs1457082371	0.1679	gnomAD-4.0.0	124	None	0.8818	0.8347	31.0	N	None	0.65	0.04817	0.295	0.219	-0.6063	0.234226866472	2.265	0.999908	0.387	0.351830644314	0.93	0.62858736515	-3.67	0.326	0.621	0.003	None	None	1.59211E-06	0	0	0	0	None	0	0	1.59211E-06	2.85901E-06	0	0	None	N	None
26476	91	T/P	None	0.1679	gnomAD-4.0.0	124	None	0.7722	0.7573	23.9	N	None	0.53	0.046348	-0.032	0.194	-0.7369	0.110713839106	2.545	0.994494	0.377	0.238096912614	0.006	0.514864325523	-4.13	0.219	0.422	0.006	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
26477	92	V/I	rs1706005880	0.6213	gnomAD-4.0.0	125	None	0.0705	0.0668	21.1	N	None	0.6	0.00609	-0.332	0.1498	-0.9248	0.0684251949703	1.51	0.998637	0.322	0.282179105231	None	0.346835494041	-0.59	0.081	0.103	0.209	None	None	4.10615E-06	0	0	0	0	None	0	0	4.10615E-06	5.39726E-06	0	0	None	N	None
26478	93	Y/C	rs1053235966	0.2634	gnomAD-4.0.0	126	None	0.1519	0.1213	35.0	N	None	0.59	0.035268	-0.927	0.3379	-0.3159	0.471626154175	1.95	0.999996	0.387	0.563910400117	1.0	0.757898747921	-6.58	0.383	0.783	0.068	None	None	1.59203E-06	0	0	0	0	None	0	0	1.59203E-06	2.85894E-06	0	0	None	N	None
26478	93	Y/D	rs768735283	0.2634	gnomAD-2.1.1	126	None	0.6338	0.5914	32.0	N	-3.206	0.58	0.054745	-0.894	0.3474	-0.2438	0.499907291575	2.185	0.999999	0.493	0.730013675969	0.993	0.751218259335	-7.0	0.539	0.869	0.085	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
26478	93	Y/D	rs768735283	0.2634	gnomAD-4.0.0	126	None	0.6338	0.5914	32.0	N	-3.206	0.58	0.054745	-0.894	0.3474	-0.2438	0.499907291575	2.185	0.999999	0.493	0.730013675969	0.993	0.751218259335	-7.0	0.539	0.869	0.085	None	None	1.59209E-06	5.65803E-05	0	0	0	None	0	0	1.59209E-06	0	0	0	None	N	None
26479	94	Y/C	None	0.2776	gnomAD-4.0.0	127	None	0.1074	0.081	33.0	N	None	0.57	0.04131	-1.356	0.2241	-0.5457	0.326512061072	2.6	0.995222	0.356	0.601923037437	0.993	0.615590274334	-6.69	0.263	0.508	0.033	None	None	1.59216E-06	0	0	0	0	None	0	0	1.59216E-06	2.85896E-06	0	0	None	I	None
26479	94	Y/F	rs747150576	0.2776	gnomAD-2.1.1	127	None	0.0867	0.0743	25.2	N	-0.485	0.6	0.029242	-0.91	0.1267	-0.8362	0.0770561423283	0.62	0.908331	0.344	0.294918367191	0.002	0.529047250748	-2.71	0.163	0.187	0.146	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	I	None
26479	94	Y/F	rs747150576	0.2776	gnomAD-4.0.0	127	None	0.0867	0.0743	25.2	N	-0.485	0.6	0.029242	-0.91	0.1267	-0.8362	0.0770561423283	0.62	0.908331	0.344	0.294918367191	0.002	0.529047250748	-2.71	0.163	0.187	0.146	None	None	1.59216E-06	5.65803E-05	0	0	0	None	0	0	1.59216E-06	0	0	0	None	I	None
26480	95	K/N	None	0.3148	gnomAD-4.0.0	129	None	0.8371	0.8055	24.8	N	None	0.6	0.01642	-0.2	0.2992	-0.44	0.334866184199	2.735	0.99983	0.4	0.144782658237	0.997	0.707412600517	-3.85	0.249	0.635	0.027	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	2.625E-06	0	0	None	N	None
26481	96	A/D	None	0.0642	gnomAD-4.0.0	130	None	0.9975	0.9973	34.0	N	None	0.49	0.049403	-3.094	0.4417	0.0009	0.563941640185	3.395	1.0	0.406	0.699497320795	1.0	0.685807585716	-4.29	0.543	0.796	0.002	None	None	1.59236E-06	0	0	0	0	None	0	0	1.59236E-06	2.85896E-06	0	0	None	N	None
26481	96	A/G	None	0.0642	gnomAD-4.0.0	130	None	0.5877	0.5474	34.0	N	None	0.49	0.035274	-1.956	0.4385	-0.0047	0.461021866798	3.395	1.0	0.304	0.570720304676	0.999	0.5954002738	-2.32	0.32	0.545	0.002	None	None	1.59236E-06	0	0	0	0	None	0	0	1.59236E-06	2.85896E-06	0	0	None	N	None
26481	96	A/V	rs1320046233	0.0642	gnomAD-2.1.1	130	None	0.7485	0.7298	34.0	N	-0.705	0.53	0.033977	-0.821	0.3021	-0.4889	0.460764587813	2.17	1.0	0.346	0.538974603628	0.999	0.62059700489	-3.08	0.325	0.647	0.158	None	None	8.06E-06	0	5.8E-05	0	0	None	0	None	8.06E-06	0	0	0	None	N	None
26481	96	A/V	rs1320046233	0.0642	gnomAD-3.1.2	130	None	0.7485	0.7298	34.0	N	-0.705	0.53	0.033977	-0.821	0.3021	-0.4889	0.460764587813	2.17	1.0	0.346	0.538974603628	0.999	0.62059700489	-3.08	0.325	0.647	0.158	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
26481	96	A/V	rs1320046233	0.0642	gnomAD-4.0.0	130	None	0.7485	0.7298	34.0	N	-0.705	0.53	0.033977	-0.821	0.3021	-0.4889	0.460764587813	2.17	1.0	0.346	0.538974603628	0.999	0.62059700489	-3.08	0.325	0.647	0.158	None	None	3.84587E-06	0	5.08768E-05	0	0	None	0	0	3.84587E-06	0	0	0	None	N	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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