TITINdb

Map SAVs to Structure

The data displayed in the table aims to be as complete as possible and contains information for all available sources including different versions of the same source, for example, different sources of gnomAD. To avoid seeing multiple entries for the same variant, we recommend to sort by Source first.

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
25304	1	V/E	1	None	0.4633	None	gnomAD-4.0.0	1.59198E-06
25305	2	P/L	2	rs142453163	0.1098	None	gnomAD-2.1.1	9.66E-05
25305	2	P/L	2	rs142453163	0.1098	None	gnomAD-3.1.2	1.11857E-04
25305	2	P/L	2	rs142453163	0.1098	None	gnomAD-4.0.0	1.20247E-04
25305	2	P/S	2	rs1005621705	0.1098	None	gnomAD-2.1.1	4.03E-06
25305	2	P/S	2	rs1005621705	0.1098	None	gnomAD-4.0.0	1.16339E-05
25306	3	D/G	3	None	0.4559	None	gnomAD-4.0.0	1.59196E-06
25306	3	D/H	3	None	0.4559	None	gnomAD-4.0.0	1.36868E-06
25306	3	D/N	3	rs1447695905	0.4559	None	gnomAD-3.1.2	6.58E-06
25306	3	D/N	3	rs1447695905	0.4559	None	gnomAD-4.0.0	6.57825E-06
25308	5	P/L	5	rs776006935	0.1158	None	gnomAD-2.1.1	1.21E-05
25308	5	P/L	5	rs776006935	0.1158	None	gnomAD-4.0.0	6.36791E-06
25310	7	A/S	7	rs1559387965	0.3157	None	gnomAD-4.0.0	1.36868E-06
25311	8	P/L	9	rs1479197659	0.1497	None	gnomAD-2.1.1	4.03E-06
25311	8	P/S	9	None	0.1497	None	gnomAD-4.0.0	1.20032E-06
25312	9	E/K	11	rs770655678	0.8073	None	gnomAD-2.1.1	1.21E-05
25312	9	E/K	11	rs770655678	0.8073	None	gnomAD-4.0.0	2.05303E-06
25313	10	V/F	12	None	0.2706	None	gnomAD-4.0.0	1.36867E-06
25313	10	V/I	12	None	0.2706	None	gnomAD-4.0.0	6.84335E-07
25314	11	T/I	13	rs1707646875	0.4423	None	gnomAD-3.1.2	6.58E-06
25314	11	T/I	13	rs1707646875	0.4423	None	gnomAD-4.0.0	6.57661E-06
25314	11	T/S	13	None	0.4423	None	gnomAD-4.0.0	1.20032E-06
25316	13	V/L	15	rs908851465	0.2397	None	gnomAD-3.1.2	6.57E-06
25316	13	V/L	15	rs908851465	0.2397	None	gnomAD-4.0.0	1.59188E-06
25316	13	V/M	15	rs908851465	0.2397	None	gnomAD-3.1.2	6.57E-06
25316	13	V/M	15	rs908851465	0.2397	None	gnomAD-4.0.0	3.84475E-06
25317	14	T/P	16	rs762723439	0.2434	None	gnomAD-4.0.0	1.59182E-06
25318	15	K/E	17	rs878854334	0.3881	None	gnomAD-4.0.0	2.05294E-06
25318	15	K/N	17	rs1001852514	0.3881	None	gnomAD-2.1.1	1.07E-05
25318	15	K/N	17	rs1001852514	0.3881	None	gnomAD-3.1.2	3.29E-05
25318	15	K/N	17	rs1001852514	0.3881	None	gnomAD-4.0.0	3.16112E-05
25320	17	S/A	19	rs772816442	0.1393	None	gnomAD-2.1.1	2.42E-05
25320	17	S/A	19	rs772816442	0.1393	None	gnomAD-3.1.2	1.97E-05
25320	17	S/A	19	rs772816442	0.1393	None	gnomAD-4.0.0	2.2313E-05
25320	17	S/P	19	rs772816442	0.1393	None	gnomAD-2.1.1	4.03E-06
25320	17	S/P	19	rs772816442	0.1393	None	gnomAD-4.0.0	6.84311E-07
25321	18	M/T	20	rs748102666	0.0780	None	gnomAD-2.1.1	4.03E-06
25321	18	M/T	20	rs748102666	0.0780	None	gnomAD-4.0.0	9.5803E-06
25321	18	M/V	20	rs769235958	0.0780	None	gnomAD-2.1.1	4.03E-06
25321	18	M/V	20	rs769235958	0.0780	None	gnomAD-3.1.2	6.57E-06
25321	18	M/V	20	rs769235958	0.0780	None	gnomAD-4.0.0	8.67728E-06
25322	19	I/T	21	None	0.2777	None	gnomAD-4.0.0	2.73724E-06
25323	20	V/A	22	rs781058398	0.0823	None	gnomAD-2.1.1	1.43E-05
25323	20	V/A	22	rs781058398	0.0823	None	gnomAD-3.1.2	6.58E-06
25323	20	V/A	22	rs781058398	0.0823	None	gnomAD-4.0.0	5.12677E-06
25323	20	V/F	22	rs1342869441	0.0823	None	gnomAD-2.1.1	4.03E-06
25323	20	V/F	22	rs1342869441	0.0823	None	gnomAD-4.0.0	1.59178E-06
25323	20	V/G	22	rs781058398	0.0823	None	gnomAD-4.0.0	1.59175E-06
25324	21	V/A	23	rs1369489276	0.3180	None	gnomAD-2.1.1	8.06E-06
25324	21	V/A	23	rs1369489276	0.3180	None	gnomAD-4.0.0	9.55079E-06
25324	21	V/L	23	None	0.3180	None	gnomAD-4.0.0	1.59177E-06
25325	22	W/C	24	rs746749916	0.1274	None	gnomAD-2.1.1	1.61E-05
25325	22	W/C	24	rs746749916	0.1274	None	gnomAD-4.0.0	1.43262E-05
25325	22	W/R	24	rs1707625464	0.1274	None	gnomAD-4.0.0	1.3686E-06
25326	23	E/G	25	rs767430531	0.5550	None	gnomAD-2.1.1	4.03E-06
25326	23	E/G	25	rs767430531	0.5550	None	gnomAD-3.1.2	1.97E-05
25326	23	E/G	25	rs767430531	0.5550	None	gnomAD-4.0.0	1.17765E-05
25327	24	R/S	26	None	0.7012	None	gnomAD-4.0.0	1.20032E-06
25328	25	P/L	27	rs758581188	0.1998	None	gnomAD-2.1.1	4.03E-06
25328	25	P/L	27	rs758581188	0.1998	None	gnomAD-3.1.2	6.58E-06
25328	25	P/L	27	rs758581188	0.1998	None	gnomAD-4.0.0	3.84299E-05
25328	25	P/S	27	rs201776072	0.1998	None	gnomAD-2.1.1	4.03E-06
25328	25	P/S	27	rs201776072	0.1998	None	gnomAD-4.0.0	6.84309E-07
25328	25	P/T	27	rs201776072	0.1998	None	gnomAD-2.1.1	8.06E-05
25328	25	P/T	27	rs201776072	0.1998	None	gnomAD-3.1.2	6.58E-06
25328	25	P/T	27	rs201776072	0.1998	None	gnomAD-4.0.0	1.36365E-05
25329	26	A/T	28	None	0.7851	None	gnomAD-4.0.0	1.59182E-06
25330	27	S/A	29	None	0.3686	None	gnomAD-4.0.0	1.20032E-06
25332	29	G/A	31	rs779031787	0.4014	None	gnomAD-2.1.1	4.03E-06
25332	29	G/A	31	rs779031787	0.4014	None	gnomAD-4.0.0	1.36862E-06
25332	29	G/D	31	rs779031787	0.4014	None	gnomAD-2.1.1	4.03E-06
25332	29	G/D	31	rs779031787	0.4014	None	gnomAD-4.0.0	1.36862E-06
25332	29	G/S	31	rs750686328	0.4014	None	gnomAD-2.1.1	4.03E-06
25332	29	G/S	31	rs750686328	0.4014	None	gnomAD-4.0.0	2.05293E-06
25333	30	G/D	32	None	0.6709	None	gnomAD-4.0.0	2.40065E-06
25333	30	G/S	32	rs757343393	0.6709	None	gnomAD-2.1.1	3.93E-05
25333	30	G/S	32	rs757343393	0.6709	None	gnomAD-3.1.2	3.29E-05
25333	30	G/S	32	rs757343393	0.6709	None	gnomAD-4.0.0	4.5246E-05
25334	31	S/R	33	None	0.2933	None	gnomAD-4.0.0	1.20032E-06
25335	32	E/Q	34	rs1416617749	0.7757	None	gnomAD-2.1.1	4.03E-06
25335	32	E/Q	34	rs1416617749	0.7757	None	gnomAD-4.0.0	1.59181E-06
25336	33	I/T	35	rs1707608600	0.2096	None	gnomAD-3.1.2	6.58E-06
25336	33	I/T	35	rs1707608600	0.2096	None	gnomAD-4.0.0	2.56322E-06
25337	34	L/I	36	rs764447275	0.5158	None	gnomAD-2.1.1	1.61E-05
25337	34	L/I	36	rs764447275	0.5158	None	gnomAD-4.0.0	6.36734E-06
25337	34	L/P	36	None	0.5158	None	gnomAD-4.0.0	1.20032E-06
25339	36	Y/C	38	rs1485371555	0.1247	None	gnomAD-2.1.1	4.03E-06
25339	36	Y/C	38	rs1485371555	0.1247	None	gnomAD-4.0.0	1.36863E-06
25339	36	Y/H	38	rs1183039680	0.1247	None	gnomAD-2.1.1	4.03E-06
25339	36	Y/H	38	rs1183039680	0.1247	None	gnomAD-4.0.0	1.59186E-06
25340	37	V/D	39	rs200287703	0.1981	None	gnomAD-2.1.1	2.21682E-04
25340	37	V/D	39	rs200287703	0.1981	None	gnomAD-3.1.2	6.2491E-04
25340	37	V/D	39	rs200287703	0.1981	None	1000 genomes	3.99361E-04
25340	37	V/D	39	rs200287703	0.1981	None	gnomAD-4.0.0	1.30157E-04
25340	37	V/I	39	rs1207970602	0.1981	None	gnomAD-2.1.1	4.03E-06
25340	37	V/I	39	rs1207970602	0.1981	None	gnomAD-3.1.2	6.58E-06
25340	37	V/I	39	rs1207970602	0.1981	None	gnomAD-4.0.0	3.84504E-06
25340	37	V/L	39	None	0.1981	None	gnomAD-4.0.0	1.59191E-06
25341	38	L/P	40	None	0.0948	None	gnomAD-4.0.0	1.59189E-06
25341	38	L/V	40	rs576067412	0.0948	None	gnomAD-2.1.1	4.03E-06
25341	38	L/V	40	rs576067412	0.0948	None	gnomAD-3.1.2	6.58E-06
25341	38	L/V	40	rs576067412	0.0948	None	1000 genomes	1.99681E-04
25341	38	L/V	40	rs576067412	0.0948	None	gnomAD-4.0.0	2.56327E-06
25342	39	E/Q	41	rs762672000	0.1522	None	gnomAD-2.1.1	1.21E-05
25342	39	E/Q	41	rs762672000	0.1522	None	gnomAD-3.1.2	6.58E-06
25342	39	E/Q	41	rs762672000	0.1522	None	gnomAD-4.0.0	3.84524E-06
25343	40	K/E	42	rs727504596	0.2171	None	gnomAD-2.1.1	4.03E-06
25343	40	K/E	42	rs727504596	0.2171	None	gnomAD-4.0.0	4.7903E-06
25344	41	R/L	43	rs556179271	0.2104	None	gnomAD-2.1.1	4.03E-06
25344	41	R/L	43	rs556179271	0.2104	None	gnomAD-4.0.0	4.10606E-06
25344	41	R/P	43	rs556179271	0.2104	None	gnomAD-2.1.1	4.03E-06
25344	41	R/Q	43	None	0.2104	None	gnomAD-2.1.1	1.21E-05
25344	41	R/Q	43	None	0.2104	None	gnomAD-3.1.2	3.29E-05
25344	41	R/Q	43	None	0.2104	None	1000 genomes	1.99681E-04
25344	41	R/Q	43	None	0.2104	None	gnomAD-4.0.0	1.48754E-05
25344	41	R/W	43	rs371696090	0.2104	None	gnomAD-2.1.1	2.01E-05
25344	41	R/W	43	rs371696090	0.2104	None	gnomAD-3.1.2	6.58E-06
25344	41	R/W	43	rs371696090	0.2104	None	gnomAD-4.0.0	6.81864E-06
25345	42	D/N	44	rs776220122	0.1710	None	gnomAD-2.1.1	8.05E-06
25345	42	D/N	44	rs776220122	0.1710	None	gnomAD-3.1.2	1.32E-05
25345	42	D/N	44	rs776220122	0.1710	None	gnomAD-4.0.0	3.84517E-06
25347	44	E/D	54	rs1310471153	0.8965	None	gnomAD-2.1.1	8.05E-06
25347	44	E/D	54	rs1310471153	0.8965	None	gnomAD-4.0.0	8.21205E-06
25348	45	G/D	60	None	0.2554	None	gnomAD-4.0.0	6.84352E-07
25348	45	G/V	60	None	0.2554	None	gnomAD-4.0.0	6.84352E-07
25349	46	I/V	63	None	0.9695	None	gnomAD-4.0.0	1.20032E-06
25351	48	W/C	65	rs1195746912	0.2150	None	gnomAD-4.0.0	1.59205E-06
25351	48	W/R	65	rs201839118	0.2150	None	gnomAD-2.1.1	4.65E-05
25351	48	W/R	65	rs201839118	0.2150	None	gnomAD-3.1.2	5.26E-05
25351	48	W/R	65	rs201839118	0.2150	None	gnomAD-4.0.0	1.28926E-04
25352	49	T/R	66	rs1318162597	0.5422	None	gnomAD-2.1.1	4.03E-06
25352	49	T/R	66	rs1318162597	0.5422	None	gnomAD-4.0.0	4.7762E-06
25352	49	T/S	66	None	0.5422	None	gnomAD-4.0.0	1.20032E-06
25353	50	R/G	67	None	0.5424	None	gnomAD-4.0.0	1.20032E-06
25353	50	R/K	67	None	0.5424	None	gnomAD-4.0.0	1.5921E-06
25355	52	H/R	69	rs1399292028	0.5437	None	gnomAD-2.1.1	4.03E-06
25355	52	H/R	69	rs1399292028	0.5437	None	gnomAD-3.1.2	6.57E-06
25355	52	H/R	69	rs1399292028	0.5437	None	gnomAD-4.0.0	3.84518E-06
25356	53	K/T	70	rs765495476	1.0668	None	gnomAD-4.0.0	1.20032E-06
25357	54	R/C	72	rs145437410	0.8453	None	gnomAD-2.1.1	3.22E-05
25357	54	R/C	72	rs145437410	0.8453	None	gnomAD-3.1.2	6.58E-06
25357	54	R/C	72	rs145437410	0.8453	None	1000 genomes	1.99681E-04
25357	54	R/C	72	rs145437410	0.8453	None	gnomAD-4.0.0	2.54132E-05
25357	54	R/H	72	rs397517703	0.8453	None	gnomAD-2.1.1	3.22E-05
25357	54	R/H	72	rs397517703	0.8453	None	gnomAD-3.1.2	1.97E-05
25357	54	R/H	72	rs397517703	0.8453	None	gnomAD-4.0.0	1.79761E-05
25357	54	R/P	72	None	0.8453	None	gnomAD-4.0.0	6.84363E-07
25358	55	L/V	75	None	0.3201	None	gnomAD-4.0.0	1.59212E-06
25359	56	I/N	77	None	0.1235	None	gnomAD-4.0.0	6.84349E-07
25359	56	I/T	77	rs779076165	0.1235	None	gnomAD-2.1.1	1.21E-05
25359	56	I/T	77	rs779076165	0.1235	None	gnomAD-4.0.0	4.1061E-06
25360	57	G/E	83	rs1158176682	0.5531	None	gnomAD-3.1.2	6.58E-06
25360	57	G/E	83	rs1158176682	0.5531	None	gnomAD-4.0.0	6.57583E-06
25360	57	G/R	83	None	0.5531	None	gnomAD-4.0.0	1.20032E-06
25362	59	L/F	89	None	0.2400	None	gnomAD-4.0.0	1.20032E-06
25362	59	L/V	89	rs1409589701	0.2400	None	gnomAD-3.1.2	6.58E-06
25362	59	L/V	89	rs1409589701	0.2400	None	gnomAD-4.0.0	6.58354E-06
25363	60	R/C	90	rs757511354	0.6571	None	gnomAD-2.1.1	1.21E-05
25363	60	R/C	90	rs757511354	0.6571	None	gnomAD-3.1.2	1.32E-05
25363	60	R/C	90	rs757511354	0.6571	None	gnomAD-4.0.0	2.85157E-05
25363	60	R/H	90	rs749274818	0.6571	None	gnomAD-2.1.1	2.51E-05
25363	60	R/H	90	rs749274818	0.6571	None	gnomAD-3.1.2	2.63E-05
25363	60	R/H	90	rs749274818	0.6571	None	gnomAD-4.0.0	2.54158E-05
25363	60	R/L	90	None	0.6571	None	gnomAD-4.0.0	6.84396E-07
25363	60	R/S	90	None	0.6571	None	gnomAD-4.0.0	1.36879E-06
25364	61	L/P	91	rs1707567452	0.2021	None	gnomAD-4.0.0	1.59225E-06
25365	62	R/G	92	None	0.6072	None	gnomAD-4.0.0	1.59223E-06
25365	62	R/K	92	None	0.6072	None	gnomAD-4.0.0	1.20032E-06
25366	63	V/I	93	None	0.1365	None	gnomAD-4.0.0	1.20032E-06
25366	63	V/L	93	rs571834965	0.1365	None	gnomAD-2.1.1	4.03E-06
25366	63	V/L	93	rs571834965	0.1365	None	gnomAD-3.1.2	6.58E-06
25366	63	V/L	93	rs571834965	0.1365	None	1000 genomes	1.99681E-04
25366	63	V/L	93	rs571834965	0.1365	None	gnomAD-4.0.0	2.02984E-06
25367	64	T/I	94	rs756655305	0.5843	None	gnomAD-2.1.1	1.21E-05
25367	64	T/I	94	rs756655305	0.5843	None	gnomAD-4.0.0	1.11467E-05
25367	64	T/N	94	None	0.5843	None	gnomAD-4.0.0	1.59239E-06
25368	65	G/R	96	rs551988703	0.4714	None	gnomAD-3.1.2	6.58E-06
25368	65	G/R	96	rs551988703	0.4714	None	1000 genomes	1.99681E-04
25368	65	G/R	96	rs551988703	0.4714	None	gnomAD-4.0.0	2.40064E-06
25368	65	G/V	96	rs753304499	0.4714	None	gnomAD-2.1.1	4.03E-06
25368	65	G/V	96	rs753304499	0.4714	None	gnomAD-4.0.0	1.59238E-06
25370	67	I/L	98	rs751411453	0.4439	None	gnomAD-2.1.1	4.04E-06
25370	67	I/L	98	rs751411453	0.4439	None	gnomAD-4.0.0	1.59254E-06
25370	67	I/T	98	rs764131874	0.4439	None	gnomAD-2.1.1	4.04E-06
25370	67	I/T	98	rs764131874	0.4439	None	gnomAD-4.0.0	6.84439E-06
25371	68	E/A	99	None	0.4245	None	gnomAD-4.0.0	6.84443E-07
25371	68	E/K	99	rs755460020	0.4245	None	gnomAD-2.1.1	4.04E-06
25371	68	E/K	99	rs755460020	0.4245	None	gnomAD-4.0.0	3.18516E-06
25371	68	E/Q	99	None	0.4245	None	gnomAD-4.0.0	1.59258E-06
25372	69	N/S	100	None	0.5748	None	gnomAD-4.0.0	1.36893E-06
25373	70	H/Q	102	rs764739209	0.3363	None	gnomAD-2.1.1	4.04E-06
25373	70	H/Q	102	rs764739209	0.3363	None	gnomAD-4.0.0	3.4227E-06
25374	71	D/G	103	None	0.2260	None	gnomAD-4.0.0	1.20032E-06
25374	71	D/H	103	None	0.2260	None	gnomAD-4.0.0	6.84549E-07
25374	71	D/N	103	rs368715583	0.2260	None	gnomAD-2.1.1	1.21E-05
25374	71	D/N	103	rs368715583	0.2260	None	gnomAD-3.1.2	6.58E-06
25374	71	D/N	103	rs368715583	0.2260	None	gnomAD-4.0.0	1.11604E-05
25375	72	Y/F	104	rs374494927	0.0954	None	gnomAD-2.1.1	3.23E-05
25375	72	Y/F	104	rs374494927	0.0954	None	gnomAD-3.1.2	6.58E-06
25375	72	Y/F	104	rs374494927	0.0954	None	gnomAD-4.0.0	8.05959E-06
25379	76	V/I	108	None	0.0693	None	gnomAD-4.0.0	1.20032E-06
25381	78	A/T	110	rs763636099	0.0806	None	gnomAD-2.1.1	8.09E-06
25381	78	A/T	110	rs763636099	0.0806	None	gnomAD-3.1.2	6.58E-06
25381	78	A/T	110	rs763636099	0.0806	None	gnomAD-4.0.0	4.96216E-06
25384	81	A/T	113	None	0.5917	None	gnomAD-4.0.0	2.73967E-06
25387	84	L/F	117	rs879225322	0.3371	None	gnomAD-3.1.2	1.32E-05
25387	84	L/F	117	rs879225322	0.3371	None	gnomAD-4.0.0	4.3417E-06
25387	84	L/I	117	None	0.3371	None	gnomAD-4.0.0	6.84812E-07
25388	85	S/R	118	rs1707543874	0.0817	None	gnomAD-4.0.0	1.20032E-06
25388	85	S/T	118	None	0.0817	None	gnomAD-4.0.0	7.20193E-06
25389	86	E/D	119	rs371435213	0.6610	None	gnomAD-2.1.1	4.05E-06
25389	86	E/D	119	rs371435213	0.6610	None	gnomAD-3.1.2	6.58E-06
25389	86	E/D	119	rs371435213	0.6610	None	gnomAD-4.0.0	6.57834E-06
25389	86	E/G	119	None	0.6610	None	gnomAD-4.0.0	1.59487E-06
25389	86	E/K	119	None	0.6610	None	gnomAD-4.0.0	1.59537E-06
25390	87	P/L	120	rs775467614	0.2952	None	gnomAD-2.1.1	8.1E-06
25390	87	P/L	120	rs775467614	0.2952	None	gnomAD-4.0.0	3.19006E-06
25390	87	P/S	120	rs878948198	0.2952	None	gnomAD-2.1.1	1.21E-05
25390	87	P/S	120	rs878948198	0.2952	None	gnomAD-3.1.2	1.32E-05
25390	87	P/S	120	rs878948198	0.2952	None	gnomAD-4.0.0	5.08679E-05
25390	87	P/T	120	None	0.2952	None	gnomAD-4.0.0	2.05472E-06
25391	88	S/I	121	None	0.0903	None	gnomAD-4.0.0	1.59509E-06
25391	88	S/R	121	None	0.0903	None	gnomAD-4.0.0	6.84885E-07
25392	89	P/H	122	None	0.4996	None	gnomAD-4.0.0	1.20032E-06
25393	90	P/S	123	rs1005590673	0.3347	None	gnomAD-4.0.0	3.18885E-06
25395	92	A/V	125	rs1311650365	0.6458	None	gnomAD-3.1.2	6.58E-06
25395	92	A/V	125	rs1311650365	0.6458	None	gnomAD-4.0.0	6.578E-06
25396	93	Y/D	126	rs771853872	0.3325	None	gnomAD-2.1.1	4.04E-06
25396	93	Y/D	126	rs771853872	0.3325	None	gnomAD-4.0.0	1.59362E-06
25398	95	K/M	129	None	0.2849	None	gnomAD-4.0.0	1.5933E-06
25398	95	K/R	129	rs1467808986	0.2849	None	gnomAD-2.1.1	4.04E-06
25398	95	K/R	129	rs1467808986	0.2849	None	gnomAD-4.0.0	1.5933E-06
25399	96	A/P	130	rs1179236670	0.0654	None	gnomAD-2.1.1	3.19E-05
25399	96	A/P	130	rs1179236670	0.0654	None	gnomAD-3.1.2	6.58E-06
25399	96	A/P	130	rs1179236670	0.0654	None	gnomAD-4.0.0	6.57947E-06
25399	96	A/T	130	None	0.0654	None	gnomAD-4.0.0	1.20032E-06
25399	96	A/V	130	rs1418217582	0.0654	None	gnomAD-2.1.1	3.19E-05
25399	96	A/V	130	rs1418217582	0.0654	None	gnomAD-3.1.2	6.58E-06
25399	96	A/V	130	rs1418217582	0.0654	None	gnomAD-4.0.0	6.57652E-06
25400	97	C/R	131	rs1575727915	0.2725	None	gnomAD-4.0.0	1.59287E-06
25400	97	C/S	131	rs397517704	0.2725	None	gnomAD-2.1.1	3.19E-05
25400	97	C/S	131	rs397517704	0.2725	None	gnomAD-3.1.2	6.58E-06
25400	97	C/S	131	rs397517704	0.2725	None	gnomAD-4.0.0	1.05401E-05
25400	97	C/W	131	None	0.2725	None	gnomAD-4.0.0	6.37135E-06
25401	98	D/E	132	None	0.4459	None	gnomAD-4.0.0	1.59274E-06
25401	98	D/V	132	rs1559385033	0.4459	None	gnomAD-2.1.1	4.04E-06
25401	98	D/V	132	rs1559385033	0.4459	None	gnomAD-4.0.0	3.18564E-06

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
25304	1	V/E	None	0.4633	gnomAD-4.0.0	1	None	0.3456	0.3681	26.8	N	None	0.48	0.045129	-0.643	0.1724	-0.784	0.163884732891	1.68	0.992757	0.526	0.647137792213	0.335	0.554882347584	-3.32	0.209	0.418	0.017	None	None	1.59198E-06	0	2.28781E-05	0	0	None	0	0	1.59198E-06	0	0	0	None	I	None
25305	2	P/L	rs142453163	0.1098	gnomAD-2.1.1	2	None	0.9443	0.937	None	D	-0.257	None	None	-0.423	None	None	None	None	None	None	None	0.027	None	None	0.475	0.622	None	None	None	9.66E-05	0	8.5E-05	0	0	None	0	None	9.66E-05	0	1.88156E-04	0	None	N	None
25305	2	P/L	rs142453163	0.1098	gnomAD-3.1.2	2	None	0.9443	0.937	None	D	-0.257	None	None	-0.423	None	None	None	None	None	None	None	0.027	None	None	0.475	0.622	None	None	None	1.11857E-04	2.42E-05	2.62467E-04	0	0	None	0	0	1.11857E-04	1.76507E-04	0	0	None	N	None
25305	2	P/L	rs142453163	0.1098	gnomAD-4.0.0	2	None	0.9443	0.937	None	D	-0.257	None	None	-0.423	None	None	None	None	None	None	None	0.027	None	None	0.475	0.622	None	None	None	1.20247E-04	1.33422E-05	1.50115E-04	0	0	None	0	0	1.20247E-04	1.54288E-04	0	3.20195E-05	None	N	None
25305	2	P/S	rs1005621705	0.1098	gnomAD-2.1.1	2	None	0.8783	0.8939	24.2	D	-2.146	-0.03	0.086284	-2.08	0.4371	0.1149	0.0967110619333	3.245	1.0	0.608	0.380394304726	0.256	0.630999565125	-6.16	0.531	0.458	0.006	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
25305	2	P/S	rs1005621705	0.1098	gnomAD-4.0.0	2	None	0.8783	0.8939	24.2	D	-2.146	-0.03	0.086284	-2.08	0.4371	0.1149	0.0967110619333	3.245	1.0	0.608	0.380394304726	0.256	0.630999565125	-6.16	0.531	0.458	0.006	None	None	1.16339E-05	0	0	0	0	None	0	0	1.16339E-05	1.52929E-05	0	0	None	N	None
25306	3	D/G	None	0.4559	gnomAD-4.0.0	3	None	0.0878	0.1005	25.4	N	None	0.39	0.0155	-0.516	0.0861	-0.9798	0.12762123978	-0.21	0.776457	0.434	0.191931220699	0.166	0.342873394489	-4.33	0.132	0.519	0.232	None	None	1.59196E-06	0	0	0	0	None	0	0	1.59196E-06	2.8593E-06	0	0	None	N	None
25306	3	D/H	None	0.4559	gnomAD-4.0.0	3	None	0.1906	0.2631	23.2	N	None	0.29	0.018145	-0.67	0.2911	-0.4028	0.100133384928	1.985	0.841856	0.453	0.269111216191	0.007	0.391179382801	-4.42	0.313	0.467	0.015	None	None	1.36868E-06	0	0	3.82848E-05	0	None	0	0	1.36868E-06	0	0	1.65706E-05	None	N	None
25306	3	D/N	rs1447695905	0.4559	gnomAD-3.1.2	3	None	0.0823	0.0982	23.3	N	None	0.33	0.01732	-0.182	0.2506	-0.5034	0.0822650963644	1.725	0.514765	0.423	0.28058544554	0.013	0.370040893555	-2.93	0.264	0.411	0.067	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
25306	3	D/N	rs1447695905	0.4559	gnomAD-4.0.0	3	None	0.0823	0.0982	23.3	N	None	0.33	0.01732	-0.182	0.2506	-0.5034	0.0822650963644	1.725	0.514765	0.423	0.28058544554	0.013	0.370040893555	-2.93	0.264	0.411	0.067	None	None	6.57825E-06	0	0	0	0	None	0	0	6.57825E-06	1.47093E-05	0	0	None	N	None
25308	5	P/L	rs776006935	0.1158	gnomAD-2.1.1	5	None	0.8198	0.8373	34.0	D	-0.847	-0.61	0.058686	-0.838	0.733	0.7551	0.469182032742	4.335	1.0	0.711	0.802005686957	1.0	0.609723389149	-7.73	0.708	0.91	0.003	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.68E-05	0	None	N	None
25308	5	P/L	rs776006935	0.1158	gnomAD-4.0.0	5	None	0.8198	0.8373	34.0	D	-0.847	-0.61	0.058686	-0.838	0.733	0.7551	0.469182032742	4.335	1.0	0.711	0.802005686957	1.0	0.609723389149	-7.73	0.708	0.91	0.003	None	None	6.36791E-06	0	0	0	0	None	0	0	6.36791E-06	1.14372E-05	0	0	None	N	None
25310	7	A/S	rs1559387965	0.3157	gnomAD-4.0.0	7	None	0.0855	0.0926	23.4	N	None	0.41	0.018529	-1.271	0.093	-0.9226	0.123287067073	-0.0049999999999999	0.973112	0.373	0.218845423259	0.285	0.376024246216	-1.23	0.083	0.369	0.676	None	None	1.36868E-06	0	0	0	0	None	0	0	1.36868E-06	1.79915E-06	0	0	None	N	None
25311	8	P/L	rs1479197659	0.1497	gnomAD-2.1.1	9	None	0.3415	0.3698	33.0	N	-0.303	0.97	0.021027	-0.603	0.1499	-0.9101	0.328482360708	0.995	0.999998	0.494	0.368369118721	0.956	0.522008776665	-5.39	0.383	0.748	1.0	None	None	4.03E-06	0	0	0	5.59E-05	None	0	None	4.03E-06	0	0	0	None	N	None
25311	8	P/S	None	0.1497	gnomAD-4.0.0	9	None	0.9363	0.9185	26.1	D	None	0.36	0.033477	-2.491	0.4924	0.2098	0.434949468536	4.01	0.999241	0.438	0.393927044628	0.997	0.463358998299	-4.87	0.4	0.776	0.037	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
25312	9	E/K	rs770655678	0.8073	gnomAD-2.1.1	11	None	0.1572	0.1614	29.2	N	0.368	0.54	0.022153	0.25	0.3198	-0.4844	0.489131336793	1.25	1.0	0.578	0.287603790349	0.999	0.618800640106	-2.94	0.39	0.628	0.176	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.68E-05	0	None	N	None
25312	9	E/K	rs770655678	0.8073	gnomAD-4.0.0	11	None	0.1572	0.1614	29.2	N	0.368	0.54	0.022153	0.25	0.3198	-0.4844	0.489131336793	1.25	1.0	0.578	0.287603790349	0.999	0.618800640106	-2.94	0.39	0.628	0.176	None	None	2.05303E-06	0	0	0	0	None	0	0	2.05303E-06	2.69874E-06	0	0	None	N	None
25313	10	V/F	None	0.2706	gnomAD-4.0.0	12	None	0.4217	0.4443	24.1	N	None	0.28	0.084246	-1.215	0.3014	-0.4967	0.238486370653	2.865	0.999909	0.564	0.619865016221	0.638	0.336173415184	-3.59	0.231	0.788	0.011	None	None	1.36867E-06	0	0	0	0	None	0	0	1.36867E-06	1.79915E-06	0	0	None	N	None
25313	10	V/I	None	0.2706	gnomAD-4.0.0	12	None	0.0656	0.0707	23.3	N	None	0.26	0.017477	-0.662	0.1422	-0.9653	0.0693580137507	1.02	0.996655	0.494	0.31291088546	0.002	0.301191389561	-0.59	0.079	0.223	0.191	None	None	6.84335E-07	0	0	0	0	None	0	0	6.84335E-07	8.99577E-07	0	0	None	N	None
25314	11	T/I	rs1707646875	0.4423	gnomAD-3.1.2	13	None	0.2987	0.2802	31.0	D	None	0.32	0.033166	-0.038	0.3406	-0.4027	0.381154881864	1.43	0.999999	0.499	0.508517017164	0.984	0.522714912891	-3.77	0.407	0.599	0.01	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
25314	11	T/I	rs1707646875	0.4423	gnomAD-4.0.0	13	None	0.2987	0.2802	31.0	D	None	0.32	0.033166	-0.038	0.3406	-0.4027	0.381154881864	1.43	0.999999	0.499	0.508517017164	0.984	0.522714912891	-3.77	0.407	0.599	0.01	None	None	6.57661E-06	0	0	0	0	None	0	0	6.57661E-06	1.4708E-05	0	0	None	N	None
25314	11	T/S	None	0.4423	gnomAD-4.0.0	13	None	0.1266	0.1299	23.3	N	None	0.49	0.012098	-0.751	0.0947	-1.0084	0.0845876680236	-0.045	0.999283	0.476	0.203808441222	0.046	0.430030852556	-1.7	0.077	0.167	0.935	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
25316	13	V/L	rs908851465	0.2397	gnomAD-3.1.2	15	None	0.2391	0.2802	22.9	N	None	0.3	0.025071	-0.648	0.2139	-0.6793	0.129028637738	2.025	0.999814	0.458	0.493494165309	0.437	0.522123157978	-1.9	0.137	0.307	0.018	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
25316	13	V/L	rs908851465	0.2397	gnomAD-4.0.0	15	None	0.2391	0.2802	22.9	N	None	0.3	0.025071	-0.648	0.2139	-0.6793	0.129028637738	2.025	0.999814	0.458	0.493494165309	0.437	0.522123157978	-1.9	0.137	0.307	0.018	None	None	1.59188E-06	0	0	0	0	None	0	0	1.59188E-06	2.85925E-06	0	0	None	N	None
25316	13	V/M	rs908851465	0.2397	gnomAD-3.1.2	15	None	0.1646	0.1946	24.9	N	None	0.21	0.031194	-0.435	0.4128	-0.0952	0.393936689695	2.435	0.999841	0.508	0.586144602217	0.968	0.546102643013	-1.98	0.363	0.436	0.005	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
25316	13	V/M	rs908851465	0.2397	gnomAD-4.0.0	15	None	0.1646	0.1946	24.9	N	None	0.21	0.031194	-0.435	0.4128	-0.0952	0.393936689695	2.435	0.999841	0.508	0.586144602217	0.968	0.546102643013	-1.98	0.363	0.436	0.005	None	None	3.84475E-06	5.07683E-05	0	0	0	None	0	0	3.84475E-06	0	0	0	None	N	None
25317	14	T/P	rs762723439	0.2434	gnomAD-4.0.0	16	None	0.8366	0.8574	25.3	D	-0.566	0.15	0.024304	-0.06	0.4076	-0.1467	0.421377757999	3.88	0.995336	0.619	0.565793286963	0.971	0.553815126419	-3.87	0.446	0.473	0.018	None	None	1.59182E-06	0	0	0	0	None	0	0	1.59182E-06	0	1.43299E-05	0	None	N	None
25318	15	K/E	rs878854334	0.3881	gnomAD-4.0.0	17	None	0.5255	0.5349	29.8	N	None	0.54	0.039956	-0.719	0.3176	-0.4225	0.543662385431	1.525	1.0	0.499	0.301122078929	0.999	0.64122736454	-2.98	0.403	0.582	0.005	None	None	2.05294E-06	0	6.71081E-05	0	0	None	0	0	2.05294E-06	0	0	0	None	N	None
25318	15	K/N	rs1001852514	0.3881	gnomAD-2.1.1	17	None	0.8336	0.8414	24.4	N	-0.362	0.45	0.073871	-0.183	0.2722	-0.6307	0.500188843923	2.16	0.999974	0.492	0.202949470691	1.0	0.660770654678	-3.85	0.248	0.757	0.004	None	None	1.07E-05	0	0	0	0	None	0	None	1.07E-05	0	2.35E-05	0	None	N	None
25318	15	K/N	rs1001852514	0.3881	gnomAD-3.1.2	17	None	0.8336	0.8414	24.4	N	-0.362	0.45	0.073871	-0.183	0.2722	-0.6307	0.500188843923	2.16	0.999974	0.492	0.202949470691	1.0	0.660770654678	-3.85	0.248	0.757	0.004	None	None	3.29E-05	2.42E-05	0	0	0	None	0	0	3.29E-05	5.88E-05	0	0	None	N	None
25318	15	K/N	rs1001852514	0.3881	gnomAD-4.0.0	17	None	0.8336	0.8414	24.4	N	-0.362	0.45	0.073871	-0.183	0.2722	-0.6307	0.500188843923	2.16	0.999974	0.492	0.202949470691	1.0	0.660770654678	-3.85	0.248	0.757	0.004	None	None	3.16112E-05	1.33583E-05	0	0	0	None	0	0	3.16112E-05	4.23863E-05	0	0	None	N	None
25320	17	S/A	rs772816442	0.1393	gnomAD-2.1.1	19	None	0.1441	0.147	28.5	N	-0.32	0.03	0.040812	-0.493	0.3226	-0.3285	0.206552446464	1.69	0.999889	0.565	0.331365685468	0.773	0.601202785969	-2.28	0.345	0.423	0.027	None	None	2.42E-05	0	0	0	0	None	0	None	2.42E-05	0	5.36E-05	0	None	N	None
25320	17	S/A	rs772816442	0.1393	gnomAD-3.1.2	19	None	0.1441	0.147	28.5	N	-0.32	0.03	0.040812	-0.493	0.3226	-0.3285	0.206552446464	1.69	0.999889	0.565	0.331365685468	0.773	0.601202785969	-2.28	0.345	0.423	0.027	None	None	1.97E-05	0	0	0	0	None	0	0	1.97E-05	4.41E-05	0	0	None	N	None
25320	17	S/A	rs772816442	0.1393	gnomAD-4.0.0	19	None	0.1441	0.147	28.5	N	-0.32	0.03	0.040812	-0.493	0.3226	-0.3285	0.206552446464	1.69	0.999889	0.565	0.331365685468	0.773	0.601202785969	-2.28	0.345	0.423	0.027	None	None	2.2313E-05	0	0	0	0	None	0	0	2.2313E-05	2.79748E-05	0	4.80446E-05	None	N	None
25320	17	S/P	rs772816442	0.1393	gnomAD-2.1.1	19	None	0.9962	0.9962	34.0	D	-0.05	-0.04	0.077242	-0.045	0.5488	0.3444	0.460658693691	3.725	0.999995	0.702	0.518752145996	0.983	0.627287566662	-3.45	0.531	0.741	0.015	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
25320	17	S/P	rs772816442	0.1393	gnomAD-4.0.0	19	None	0.9962	0.9962	34.0	D	-0.05	-0.04	0.077242	-0.045	0.5488	0.3444	0.460658693691	3.725	0.999995	0.702	0.518752145996	0.983	0.627287566662	-3.45	0.531	0.741	0.015	None	None	6.84311E-07	0	0	0	0	None	0	0	6.84311E-07	8.99567E-07	0	0	None	N	None
25321	18	M/T	rs748102666	0.0780	gnomAD-2.1.1	20	None	0.8527	0.866	31.0	N	-1.677	0.39	0.074368	-1.975	0.41	-0.0677	0.488469659113	3.035	1.0	0.677	0.754413127693	0.994	0.69187515974	-4.37	0.535	0.764	0.008	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
25321	18	M/T	rs748102666	0.0780	gnomAD-4.0.0	20	None	0.8527	0.866	31.0	N	-1.677	0.39	0.074368	-1.975	0.41	-0.0677	0.488469659113	3.035	1.0	0.677	0.754413127693	0.994	0.69187515974	-4.37	0.535	0.764	0.008	None	None	9.5803E-06	0	0	0	0	None	0	1.73732E-04	9.5803E-06	1.07948E-05	0	1.65695E-05	None	N	None
25321	18	M/V	rs769235958	0.0780	gnomAD-2.1.1	20	None	0.1966	0.2228	26.4	N	-0.705	0.64	0.038977	-1.189	0.1563	-0.6828	0.455994801244	-0.16	1.0	0.591	0.521070178209	0.985	0.523245334625	-2.92	0.425	0.533	0.032	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
25321	18	M/V	rs769235958	0.0780	gnomAD-3.1.2	20	None	0.1966	0.2228	26.4	N	-0.705	0.64	0.038977	-1.189	0.1563	-0.6828	0.455994801244	-0.16	1.0	0.591	0.521070178209	0.985	0.523245334625	-2.92	0.425	0.533	0.032	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
25321	18	M/V	rs769235958	0.0780	gnomAD-4.0.0	20	None	0.1966	0.2228	26.4	N	-0.705	0.64	0.038977	-1.189	0.1563	-0.6828	0.455994801244	-0.16	1.0	0.591	0.521070178209	0.985	0.523245334625	-2.92	0.425	0.533	0.032	None	None	8.67728E-06	0	0	0	0	None	0	0	8.67728E-06	1.18682E-05	0	0	None	N	None
25322	19	I/T	None	0.2777	gnomAD-4.0.0	21	None	0.1783	0.1297	24.2	N	None	0.58	0.016613	-1.815	0.0439	-1.0271	0.105969166871	-1.905	0.676035	0.408	0.319970858106	None	0.482210576534	-3.33	0.14	0.258	0.391	None	None	2.73724E-06	0	0	0	0	None	0	0	2.73724E-06	3.5983E-06	0	0	None	N	None
25323	20	V/A	rs781058398	0.0823	gnomAD-2.1.1	22	None	0.6155	0.6375	33.0	N	-2.481	0.24	0.024033	-2.174	0.4399	0.1259	0.379395075477	2.745	0.999884	0.611	0.714052572023	0.978	0.677294909954	-3.09	0.461	0.668	0.005	None	None	1.43E-05	0	8.49E-05	0	0	None	0	None	1.43E-05	4E-05	0	0	None	N	None
25323	20	V/A	rs781058398	0.0823	gnomAD-3.1.2	22	None	0.6155	0.6375	33.0	N	-2.481	0.24	0.024033	-2.174	0.4399	0.1259	0.379395075477	2.745	0.999884	0.611	0.714052572023	0.978	0.677294909954	-3.09	0.461	0.668	0.005	None	None	6.58E-06	0	0	0	0	None	9.43E-05	0	6.58E-06	0	0	0	None	N	None
25323	20	V/A	rs781058398	0.0823	gnomAD-4.0.0	22	None	0.6155	0.6375	33.0	N	-2.481	0.24	0.024033	-2.174	0.4399	0.1259	0.379395075477	2.745	0.999884	0.611	0.714052572023	0.978	0.677294909954	-3.09	0.461	0.668	0.005	None	None	5.12677E-06	0	5.08751E-05	0	0	None	1.56912E-05	0	5.12677E-06	0	0	0	None	N	None
25323	20	V/F	rs1342869441	0.0823	gnomAD-2.1.1	22	None	0.8943	0.895	26.8	N	-1.637	0.27	0.04753	-1.255	0.4879	0.0831	0.48814725497	2.945	0.999923	0.6	0.771885699435	0.994	0.641484439373	-3.46	0.393	0.729	0.007	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
25323	20	V/F	rs1342869441	0.0823	gnomAD-4.0.0	22	None	0.8943	0.895	26.8	N	-1.637	0.27	0.04753	-1.255	0.4879	0.0831	0.48814725497	2.945	0.999923	0.6	0.771885699435	0.994	0.641484439373	-3.46	0.393	0.729	0.007	None	None	1.59178E-06	0	0	0	0	None	0	0	1.59178E-06	0	1.43295E-05	0	None	N	None
25323	20	V/G	rs781058398	0.0823	gnomAD-4.0.0	22	None	0.9215	0.9152	34.0	D	None	0.2	0.039515	-2.782	0.5359	0.3743	0.511671324212	3.295	1.0	0.671	0.872732203694	0.999	0.569274067879	-5.51	0.583	0.887	0.002	None	None	1.59175E-06	0	0	0	0	None	0	0	1.59175E-06	2.85917E-06	0	0	None	N	None
25324	21	V/A	rs1369489276	0.3180	gnomAD-2.1.1	23	None	0.173	0.1894	26.1	N	-2.074	0.5	0.029135	-1.727	0.0998	-0.8508	0.253901594221	-0.98	0.990441	0.369	0.527908583987	0.91	0.537068724632	-2.26	0.222	0.394	0.335	None	None	8.06E-06	0	0	0	0	None	0	None	8.06E-06	9.29E-05	0	0	None	N	None
25324	21	V/A	rs1369489276	0.3180	gnomAD-4.0.0	23	None	0.173	0.1894	26.1	N	-2.074	0.5	0.029135	-1.727	0.0998	-0.8508	0.253901594221	-0.98	0.990441	0.369	0.527908583987	0.91	0.537068724632	-2.26	0.222	0.394	0.335	None	None	9.55079E-06	0	0	0	0	None	1.12952E-04	0	9.55079E-06	0	0	0	None	N	None
25324	21	V/L	None	0.3180	gnomAD-4.0.0	23	None	0.1888	0.2114	23.6	N	None	0.48	0.037918	-0.501	0.1213	-0.8846	0.178162087791	0.445	0.994718	0.41	0.536616348568	0.835	0.520915091038	-1.89	0.198	0.405	0.151	None	None	1.59177E-06	0	0	0	0	None	0	0	1.59177E-06	2.85925E-06	0	0	None	N	None
25325	22	W/C	rs746749916	0.1274	gnomAD-2.1.1	24	None	0.9982	0.9966	34.0	D	-1.706	-2.1	0.612571	-1.835	0.906	1.059	0.580146131267	4.675	1.0	0.895	0.862623283075	1.0	0.76978456974	-10.05	0.813	0.877	0.001	None	None	1.61E-05	0	0	0	0	None	1.30762E-04	None	1.61E-05	0	0	0	None	N	None
25325	22	W/C	rs746749916	0.1274	gnomAD-4.0.0	24	None	0.9982	0.9966	34.0	D	-1.706	-2.1	0.612571	-1.835	0.906	1.059	0.580146131267	4.675	1.0	0.895	0.862623283075	1.0	0.76978456974	-10.05	0.813	0.877	0.001	None	None	1.43262E-05	0	0	0	0	None	0	0	1.43262E-05	0	1.28966E-04	0	None	N	None
25325	22	W/R	rs1707625464	0.1274	gnomAD-4.0.0	24	None	0.9996	0.9993	32.0	D	None	-2.1	0.563684	-2.765	0.8976	1.0762	0.615612516959	4.675	1.0	0.886	0.945312082423	1.0	0.800892293453	-10.6	0.848	0.921	None	None	None	1.3686E-06	0	0	0	0	None	0	0	1.3686E-06	8.99565E-07	0	1.65689E-05	None	N	None
25326	23	E/G	rs767430531	0.5550	gnomAD-2.1.1	25	None	0.1069	0.1137	26.9	N	-0.857	0.27	0.047125	-0.633	0.1972	-0.8244	0.0997905954404	1.8	0.999997	0.449	0.275215494804	0.014	0.560148835182	-5.31	0.191	0.333	0.017	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
25326	23	E/G	rs767430531	0.5550	gnomAD-3.1.2	25	None	0.1069	0.1137	26.9	N	-0.857	0.27	0.047125	-0.633	0.1972	-0.8244	0.0997905954404	1.8	0.999997	0.449	0.275215494804	0.014	0.560148835182	-5.31	0.191	0.333	0.017	None	None	1.97E-05	2.41E-05	0	0	0	None	0	0	1.97E-05	2.94E-05	0	0	None	N	None
25326	23	E/G	rs767430531	0.5550	gnomAD-4.0.0	25	None	0.1069	0.1137	26.9	N	-0.857	0.27	0.047125	-0.633	0.1972	-0.8244	0.0997905954404	1.8	0.999997	0.449	0.275215494804	0.014	0.560148835182	-5.31	0.191	0.333	0.017	None	None	1.17765E-05	1.33554E-05	0	0	0	None	0	0	1.17765E-05	1.44114E-05	0	1.60154E-05	None	N	None
25327	24	R/S	None	0.7012	gnomAD-4.0.0	26	None	0.7134	0.7451	22.9	D	None	0.45	0.033999	-0.621	0.173	-0.8094	0.291971285333	1.575	0.985589	0.487	0.213573922156	0.805	0.590381264687	-4.07	0.225	0.615	0.142	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25328	25	P/L	rs758581188	0.1998	gnomAD-2.1.1	27	None	0.9655	0.9601	34.0	D	-0.795	-0.83	0.133321	-1.037	0.7606	0.7885	0.469182032742	4.245	1.0	0.696	0.850381006097	1.0	0.688567996025	-7.55	0.696	0.937	None	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
25328	25	P/L	rs758581188	0.1998	gnomAD-3.1.2	27	None	0.9655	0.9601	34.0	D	-0.795	-0.83	0.133321	-1.037	0.7606	0.7885	0.469182032742	4.245	1.0	0.696	0.850381006097	1.0	0.688567996025	-7.55	0.696	0.937	None	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
25328	25	P/L	rs758581188	0.1998	gnomAD-4.0.0	27	None	0.9655	0.9601	34.0	D	-0.795	-0.83	0.133321	-1.037	0.7606	0.7885	0.469182032742	4.245	1.0	0.696	0.850381006097	1.0	0.688567996025	-7.55	0.696	0.937	None	None	None	3.84299E-05	0	0	0	0	None	0	0	3.84299E-05	5.25597E-05	0	0	None	N	None
25328	25	P/S	rs201776072	0.1998	gnomAD-2.1.1	27	None	0.9803	0.9684	32.0	D	-2.406	-0.83	0.067865	-2.076	0.657	0.3942	0.466644225527	2.84	1.0	0.676	0.612736520223	1.0	0.634595513344	-6.17	0.629	0.911	None	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
25328	25	P/S	rs201776072	0.1998	gnomAD-4.0.0	27	None	0.9803	0.9684	32.0	D	-2.406	-0.83	0.067865	-2.076	0.657	0.3942	0.466644225527	2.84	1.0	0.676	0.612736520223	1.0	0.634595513344	-6.17	0.629	0.911	None	None	None	6.84309E-07	0	0	0	0	None	0	0	6.84309E-07	0	1.1595E-05	0	None	N	None
25328	25	P/T	rs201776072	0.1998	gnomAD-2.1.1	27	None	0.9743	0.9628	32.0	D	-2.089	-0.86	0.089385	-1.925	0.7201	0.6331	0.48919594472	3.695	1.0	0.709	0.657750020267	1.0	0.663401007652	-6.13	0.684	0.913	None	None	None	8.06E-05	0	5.80215E-04	0	0	None	0	None	8.06E-05	0	0	0	None	N	None
25328	25	P/T	rs201776072	0.1998	gnomAD-3.1.2	27	None	0.9743	0.9628	32.0	D	-2.089	-0.86	0.089385	-1.925	0.7201	0.6331	0.48919594472	3.695	1.0	0.709	0.657750020267	1.0	0.663401007652	-6.13	0.684	0.913	None	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
25328	25	P/T	rs201776072	0.1998	gnomAD-4.0.0	27	None	0.9743	0.9628	32.0	D	-2.089	-0.86	0.089385	-1.925	0.7201	0.6331	0.48919594472	3.695	1.0	0.709	0.657750020267	1.0	0.663401007652	-6.13	0.684	0.913	None	None	None	1.36365E-05	0	3.50198E-04	0	0	None	0	0	1.36365E-05	0	0	1.60159E-05	None	N	None
25329	26	A/T	None	0.7851	gnomAD-4.0.0	28	None	0.0696	0.0731	23.7	N	None	0.43	0.01998	-0.491	0.0947	-0.9587	0.082290412646	0.02	0.886706	0.274	0.152612264143	0.007	0.367701530457	-1.7	0.086	0.071	0.578	None	None	1.59182E-06	0	0	0	0	None	0	0	1.59182E-06	0	1.43299E-05	0	None	I	None
25330	27	S/A	None	0.3686	gnomAD-4.0.0	29	None	0.0797	0.0983	23.5	N	None	0.56	0.038936	-0.395	0.185	-0.8265	0.0849568686431	1.335	0.937819	0.343	0.152612264143	0.052	0.452391177416	-2.17	0.101	0.422	0.126	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25332	29	G/A	rs779031787	0.4014	gnomAD-2.1.1	31	None	0.9064	0.8875	28.5	D	-0.124	0.42	0.022956	-0.197	0.5115	0.2399	0.480971576196	3.67	1.0	0.719	0.397540356873	1.0	0.645990014076	-4.61	0.557	0.733	None	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	I	None
25332	29	G/A	rs779031787	0.4014	gnomAD-4.0.0	31	None	0.9064	0.8875	28.5	D	-0.124	0.42	0.022956	-0.197	0.5115	0.2399	0.480971576196	3.67	1.0	0.719	0.397540356873	1.0	0.645990014076	-4.61	0.557	0.733	None	None	None	1.36862E-06	0	0	0	0	None	0	0	1.36862E-06	1.79914E-06	0	0	None	I	None
25332	29	G/D	rs779031787	0.4014	gnomAD-2.1.1	31	None	0.9912	0.9844	29.4	D	None	0.45	0.03159	-0.719	0.5115	0.2399	0.527275360279	3.59	1.0	0.769	0.428976297845	1.0	0.727522850037	-5.06	0.676	0.823	None	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	I	None
25332	29	G/D	rs779031787	0.4014	gnomAD-4.0.0	31	None	0.9912	0.9844	29.4	D	None	0.45	0.03159	-0.719	0.5115	0.2399	0.527275360279	3.59	1.0	0.769	0.428976297845	1.0	0.727522850037	-5.06	0.676	0.823	None	None	None	1.36862E-06	0	0	0	0	None	0	0	1.36862E-06	1.79914E-06	0	0	None	I	None
25332	29	G/S	rs750686328	0.4014	gnomAD-2.1.1	31	None	0.8648	0.8217	29.8	N	-0.295	0.46	0.036058	-0.327	0.501	0.1949	0.463496485926	3.525	1.0	0.67	0.386721274199	1.0	0.64982521534	-4.53	0.525	0.798	None	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	I	None
25332	29	G/S	rs750686328	0.4014	gnomAD-4.0.0	31	None	0.8648	0.8217	29.8	N	-0.295	0.46	0.036058	-0.327	0.501	0.1949	0.463496485926	3.525	1.0	0.67	0.386721274199	1.0	0.64982521534	-4.53	0.525	0.798	None	None	None	2.05293E-06	0	0	0	0	None	0	0	2.05293E-06	1.79914E-06	1.1595E-05	0	None	I	None
25333	30	G/D	None	0.6709	gnomAD-4.0.0	32	None	0.825	0.8275	29.6	D	None	-0.12	0.07023	-0.378	0.5838	0.3409	0.527275360279	3.815	1.0	0.476	0.505335117028	1.0	0.693818330765	-5.38	0.576	0.739	None	None	None	2.40065E-06	0	0	0	0	None	0	0	2.40065E-06	2.62501E-06	0	0	None	I	None
25333	30	G/S	rs757343393	0.6709	gnomAD-2.1.1	32	None	0.4704	0.5389	None	N	-0.157	None	None	-0.313	None	None	None	None	None	None	None	1.0	None	None	0.496	0.733	None	None	None	3.93E-05	4.13E-05	0	0	0	None	0	None	3.93E-05	0	7.84E-05	0	None	I	None
25333	30	G/S	rs757343393	0.6709	gnomAD-3.1.2	32	None	0.4704	0.5389	None	N	-0.157	None	None	-0.313	None	None	None	None	None	None	None	1.0	None	None	0.496	0.733	None	None	None	3.29E-05	2.41E-05	0	0	0	None	0	0	3.29E-05	5.88E-05	0	0	None	I	None
25333	30	G/S	rs757343393	0.6709	gnomAD-4.0.0	32	None	0.4704	0.5389	None	N	-0.157	None	None	-0.313	None	None	None	None	None	None	None	1.0	None	None	0.496	0.733	None	None	None	4.5246E-05	1.33554E-05	0	0	0	None	0	0	4.5246E-05	5.76449E-05	2.19611E-05	3.20277E-05	None	I	None
25334	31	S/R	None	0.2933	gnomAD-4.0.0	33	None	0.8782	0.8456	33.0	N	None	0.38	0.038709	-0.357	0.3138	-0.3704	0.388394349239	2.855	0.999969	0.558	0.371718192555	0.97	0.610284566879	-3.79	0.438	0.621	0.003	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25335	32	E/Q	rs1416617749	0.7757	gnomAD-2.1.1	34	None	0.1735	0.1972	29.1	N	0.31	0.31	0.031283	0.076	0.3503	-0.3349	0.353122222173	1.975	0.975965	0.469	0.240491677333	0.959	0.573714256287	-1.73	0.246	0.362	0.141	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	0	1.66003E-04	None	I	None
25335	32	E/Q	rs1416617749	0.7757	gnomAD-4.0.0	34	None	0.1735	0.1972	29.1	N	0.31	0.31	0.031283	0.076	0.3503	-0.3349	0.353122222173	1.975	0.975965	0.469	0.240491677333	0.959	0.573714256287	-1.73	0.246	0.362	0.141	None	None	1.59181E-06	0	0	0	0	None	0	0	1.59181E-06	0	0	3.02535E-05	None	I	None
25336	33	I/T	rs1707608600	0.2096	gnomAD-3.1.2	35	None	0.9696	0.9704	33.0	D	None	0.03	0.055557	-2.262	0.5485	0.3198	0.51877166463	3.495	1.0	0.669	0.756051586483	1.0	0.843002200127	-3.63	0.562	0.858	0.002	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
25336	33	I/T	rs1707608600	0.2096	gnomAD-4.0.0	35	None	0.9696	0.9704	33.0	D	None	0.03	0.055557	-2.262	0.5485	0.3198	0.51877166463	3.495	1.0	0.669	0.756051586483	1.0	0.843002200127	-3.63	0.562	0.858	0.002	None	None	2.56322E-06	0	3.39109E-05	0	0	None	0	0	2.56322E-06	0	0	0	None	I	None
25337	34	L/I	rs764447275	0.5158	gnomAD-2.1.1	36	None	0.0672	0.0768	23.9	N	-0.438	0.36	0.011654	-0.46	0.0883	-1.0145	0.164595594788	0.19	0.979923	0.412	0.402899589544	0.801	0.596944928169	-1.13	0.142	0.286	0.3	None	None	1.61E-05	0	0	0	0	None	0	None	1.61E-05	0	3.57E-05	0	None	I	None
25337	34	L/I	rs764447275	0.5158	gnomAD-4.0.0	36	None	0.0672	0.0768	23.9	N	-0.438	0.36	0.011654	-0.46	0.0883	-1.0145	0.164595594788	0.19	0.979923	0.412	0.402899589544	0.801	0.596944928169	-1.13	0.142	0.286	0.3	None	None	6.36734E-06	0	0	0	0	None	0	0	6.36734E-06	1.14373E-05	0	0	None	I	None
25337	34	L/P	None	0.5158	gnomAD-4.0.0	36	None	0.5882	0.5917	29.8	N	None	0.32	0.04919	-0.564	0.3328	-0.3227	0.409156735794	2.77	0.999955	0.583	0.783275769904	0.966	0.671580910683	-3.9	0.415	0.387	0.09	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25339	36	Y/C	rs1485371555	0.1247	gnomAD-2.1.1	38	None	0.9178	0.9116	34.0	D	-1.365	-1.48	0.411126	-1.392	0.8329	0.9927	0.517459491388	4.66	1.0	0.82	0.874236787041	1.0	0.751948773861	-6.21	0.89	0.863	None	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
25339	36	Y/C	rs1485371555	0.1247	gnomAD-4.0.0	38	None	0.9178	0.9116	34.0	D	-1.365	-1.48	0.411126	-1.392	0.8329	0.9927	0.517459491388	4.66	1.0	0.82	0.874236787041	1.0	0.751948773861	-6.21	0.89	0.863	None	None	None	1.36863E-06	0	0	0	0	None	0	0	1.36863E-06	8.99585E-07	1.15947E-05	0	None	N	None
25339	36	Y/H	rs1183039680	0.1247	gnomAD-2.1.1	38	None	0.9813	0.9823	29.6	D	-2.751	-1.46	0.270861	-2.394	0.8146	0.9395	0.52537510995	4.66	1.0	0.811	0.751392580583	1.0	0.753672719002	-4.08	0.864	0.797	None	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
25339	36	Y/H	rs1183039680	0.1247	gnomAD-4.0.0	38	None	0.9813	0.9823	29.6	D	-2.751	-1.46	0.270861	-2.394	0.8146	0.9395	0.52537510995	4.66	1.0	0.811	0.751392580583	1.0	0.753672719002	-4.08	0.864	0.797	None	None	None	1.59186E-06	5.66251E-05	0	0	0	None	0	0	1.59186E-06	0	0	0	None	N	None
25340	37	V/D	rs200287703	0.1981	gnomAD-2.1.1	39	None	0.7772	0.7757	None	N	-3.521	None	None	-2.973	None	None	None	None	None	None	None	0.979	None	None	0.46	0.758	None	None	None	2.21682E-04	2.06731E-03	3.11333E-04	0	0	None	0	None	2.21682E-04	0	0	1.40449E-04	None	N	None
25340	37	V/D	rs200287703	0.1981	gnomAD-3.1.2	39	None	0.7772	0.7757	None	N	-3.521	None	None	-2.973	None	None	None	None	None	None	None	0.979	None	None	0.46	0.758	None	None	None	6.2491E-04	2.10145E-03	4.58595E-04	0	0	None	0	0	6.2491E-04	0	0	4.78011E-04	None	N	None
25340	37	V/D	rs200287703	0.1981	1000 genomes	39	None	0.7772	0.7757	None	N	-3.521	None	None	-2.973	None	None	None	None	None	None	None	0.979	None	None	0.46	0.758	None	None	None	3.99361E-04	1.5E-03	0	None	0	0	None	None	3.99361E-04	None	0	None	None	N	None
25340	37	V/D	rs200287703	0.1981	gnomAD-4.0.0	39	None	0.7772	0.7757	None	N	-3.521	None	None	-2.973	None	None	None	None	None	None	None	0.979	None	None	0.46	0.758	None	None	None	1.30157E-04	2.46772E-03	3.0002E-04	0	0	None	0	0	1.30157E-04	0	0	1.12061E-04	None	N	None
25340	37	V/I	rs1207970602	0.1981	gnomAD-2.1.1	39	None	0.065	0.0723	23.2	N	-0.821	0.42	0.010856	-0.934	0.0713	-0.9835	0.0702435888376	-1.15	0.668949	0.433	0.268660756437	0.003	0.478303670883	-0.42	0.073	0.263	0.596	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
25340	37	V/I	rs1207970602	0.1981	gnomAD-3.1.2	39	None	0.065	0.0723	23.2	N	-0.821	0.42	0.010856	-0.934	0.0713	-0.9835	0.0702435888376	-1.15	0.668949	0.433	0.268660756437	0.003	0.478303670883	-0.42	0.073	0.263	0.596	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
25340	37	V/I	rs1207970602	0.1981	gnomAD-4.0.0	39	None	0.065	0.0723	23.2	N	-0.821	0.42	0.010856	-0.934	0.0713	-0.9835	0.0702435888376	-1.15	0.668949	0.433	0.268660756437	0.003	0.478303670883	-0.42	0.073	0.263	0.596	None	None	3.84504E-06	3.38513E-05	0	0	0	None	0	0	3.84504E-06	0	0	2.84527E-05	None	N	None
25340	37	V/L	None	0.1981	gnomAD-4.0.0	39	None	0.1492	0.1856	23.5	N	None	0.46	0.024238	-0.934	0.1164	-0.8618	0.120216512759	0.6	0.883617	0.499	0.37550373646	0.164	0.631349086761	-1.93	0.109	0.523	0.155	None	None	1.59191E-06	0	0	0	0	None	0	0	1.59191E-06	0	1.43299E-05	0	None	N	None
25341	38	L/P	None	0.0948	gnomAD-4.0.0	40	None	0.9874	0.984	35.0	N	None	0.14	0.076861	-1.834	0.431	-0.0497	0.570027948751	3.03	1.0	0.759	0.703937047953	0.999	0.734187543392	-4.63	0.645	0.872	0.002	None	None	1.59189E-06	0	0	0	0	None	0	0	1.59189E-06	2.85941E-06	0	0	None	N	None
25341	38	L/V	rs576067412	0.0948	gnomAD-2.1.1	40	None	0.0786	0.0801	23.7	N	-2.124	0.95	0.010226	-1.834	0.0569	-1.0315	0.11206063664	-0.78	0.997649	0.48	0.29527378943	0.198	0.585420012474	-1.1	0.098	0.309	0.595	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
25341	38	L/V	rs576067412	0.0948	gnomAD-3.1.2	40	None	0.0786	0.0801	23.7	N	-2.124	0.95	0.010226	-1.834	0.0569	-1.0315	0.11206063664	-0.78	0.997649	0.48	0.29527378943	0.198	0.585420012474	-1.1	0.098	0.309	0.595	None	None	6.58E-06	2.42E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
25341	38	L/V	rs576067412	0.0948	1000 genomes	40	None	0.0786	0.0801	23.7	N	-2.124	0.95	0.010226	-1.834	0.0569	-1.0315	0.11206063664	-0.78	0.997649	0.48	0.29527378943	0.198	0.585420012474	-1.1	0.098	0.309	0.595	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	N	None
25341	38	L/V	rs576067412	0.0948	gnomAD-4.0.0	40	None	0.0786	0.0801	23.7	N	-2.124	0.95	0.010226	-1.834	0.0569	-1.0315	0.11206063664	-0.78	0.997649	0.48	0.29527378943	0.198	0.585420012474	-1.1	0.098	0.309	0.595	None	None	2.56327E-06	3.38066E-05	0	0	0	None	0	0	2.56327E-06	0	0	0	None	N	None
25342	39	E/Q	rs762672000	0.1522	gnomAD-2.1.1	41	None	0.6209	0.5469	28.1	N	-1.796	0.4	0.023732	-1.762	0.3871	-0.2744	0.461673312431	2.325	1.0	0.476	0.363158594168	1.0	0.658907234669	-2.3	0.346	0.739	0.005	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.67E-05	0	None	N	None
25342	39	E/Q	rs762672000	0.1522	gnomAD-3.1.2	41	None	0.6209	0.5469	28.1	N	-1.796	0.4	0.023732	-1.762	0.3871	-0.2744	0.461673312431	2.325	1.0	0.476	0.363158594168	1.0	0.658907234669	-2.3	0.346	0.739	0.005	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
25342	39	E/Q	rs762672000	0.1522	gnomAD-4.0.0	41	None	0.6209	0.5469	28.1	N	-1.796	0.4	0.023732	-1.762	0.3871	-0.2744	0.461673312431	2.325	1.0	0.476	0.363158594168	1.0	0.658907234669	-2.3	0.346	0.739	0.005	None	None	3.84524E-06	0	0	0	0	None	0	0	3.84524E-06	7.18236E-06	0	0	None	N	None
25343	40	K/E	rs727504596	0.2171	gnomAD-2.1.1	42	None	0.9707	0.9646	32.0	N	-2.253	0.38	0.064158	-1.845	0.3359	-0.2637	0.428468608251	3.55	0.999999	0.604	0.348764635752	0.944	0.750834822655	-2.89	0.456	0.725	0.004	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
25343	40	K/E	rs727504596	0.2171	gnomAD-4.0.0	42	None	0.9707	0.9646	32.0	N	-2.253	0.38	0.064158	-1.845	0.3359	-0.2637	0.428468608251	3.55	0.999999	0.604	0.348764635752	0.944	0.750834822655	-2.89	0.456	0.725	0.004	None	None	4.7903E-06	0	0	0	0	None	0	0	4.7903E-06	5.39757E-06	0	1.65695E-05	None	N	None
25344	41	R/L	rs556179271	0.2104	gnomAD-2.1.1	43	None	0.8636	0.8423	31.0	N	-1.088	0.31	0.082322	-1.217	0.4051	-0.0429	0.426408842534	2.24	0.999326	0.712	0.354822389136	0.954	0.769677400589	-5.16	0.478	0.645	0.005	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
25344	41	R/L	rs556179271	0.2104	gnomAD-4.0.0	43	None	0.8636	0.8423	31.0	N	-1.088	0.31	0.082322	-1.217	0.4051	-0.0429	0.426408842534	2.24	0.999326	0.712	0.354822389136	0.954	0.769677400589	-5.16	0.478	0.645	0.005	None	None	4.10606E-06	0	0	0	0	None	0	0	4.10606E-06	5.39754E-06	0	0	None	N	None
25344	41	R/P	rs556179271	0.2104	gnomAD-2.1.1	43	None	0.999	0.9988	33.0	D	-1.67	0.27	0.119751	-1.532	0.5439	0.4409	0.531189944382	3.825	0.999386	0.718	0.489036454283	0.993	0.779492557049	-4.89	0.488	0.759	0.004	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
25344	41	R/Q	None	0.2104	gnomAD-2.1.1	43	None	0.3882	0.35	31.0	N	-1.166	0.4	0.036033	-1.149	0.3031	-0.3419	0.378906110955	2.235	0.995177	0.708	0.300449992093	0.994	0.709218978882	-2.58	0.335	0.571	0.011	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.67E-05	0	None	N	None
25344	41	R/Q	None	0.2104	gnomAD-3.1.2	43	None	0.3882	0.35	31.0	N	-1.166	0.4	0.036033	-1.149	0.3031	-0.3419	0.378906110955	2.235	0.995177	0.708	0.300449992093	0.994	0.709218978882	-2.58	0.335	0.571	0.011	None	None	3.29E-05	0	3.27783E-04	0	0	None	0	0	3.29E-05	0	0	0	None	N	None
25344	41	R/Q	None	0.2104	1000 genomes	43	None	0.3882	0.35	31.0	N	-1.166	0.4	0.036033	-1.149	0.3031	-0.3419	0.378906110955	2.235	0.995177	0.708	0.300449992093	0.994	0.709218978882	-2.58	0.335	0.571	0.011	None	None	1.99681E-04	0	1.4E-03	None	0	0	None	None	1.99681E-04	None	0	None	None	N	None
25344	41	R/Q	None	0.2104	gnomAD-4.0.0	43	None	0.3882	0.35	31.0	N	-1.166	0.4	0.036033	-1.149	0.3031	-0.3419	0.378906110955	2.235	0.995177	0.708	0.300449992093	0.994	0.709218978882	-2.58	0.335	0.571	0.011	None	None	1.48754E-05	0	2.0006E-04	0	2.23244E-05	None	0	0	1.48754E-05	8.47759E-06	0	1.60097E-05	None	N	None
25344	41	R/W	rs371696090	0.2104	gnomAD-2.1.1	43	None	0.6834	0.6619	None	N	-0.831	None	None	-0.87	None	None	None	None	None	None	None	1.0	None	None	0.473	0.703	None	None	None	2.01E-05	0	0	0	5.58E-05	None	9.81E-05	None	2.01E-05	0	8.91E-06	0	None	N	None
25344	41	R/W	rs371696090	0.2104	gnomAD-3.1.2	43	None	0.6834	0.6619	None	N	-0.831	None	None	-0.87	None	None	None	None	None	None	None	1.0	None	None	0.473	0.703	None	None	None	6.58E-06	0	0	0	0	None	9.44E-05	0	6.58E-06	0	0	0	None	N	None
25344	41	R/W	rs371696090	0.2104	gnomAD-4.0.0	43	None	0.6834	0.6619	None	N	-0.831	None	None	-0.87	None	None	None	None	None	None	None	1.0	None	None	0.473	0.703	None	None	None	6.81864E-06	0	0	0	2.23164E-05	None	1.56323E-05	0	6.81864E-06	2.54328E-06	6.58877E-05	0	None	N	None
25345	42	D/N	rs776220122	0.1710	gnomAD-2.1.1	44	None	0.49	0.4221	27.4	N	-1.387	0.43	0.021099	-1.639	0.3771	-0.3103	0.459178880736	2.35	1.0	0.501	0.481915485015	1.0	0.715682625771	-3.71	0.397	0.668	0.005	None	None	8.05E-06	1.29232E-04	0	0	0	None	0	None	8.05E-06	0	0	0	None	N	None
25345	42	D/N	rs776220122	0.1710	gnomAD-3.1.2	44	None	0.49	0.4221	27.4	N	-1.387	0.43	0.021099	-1.639	0.3771	-0.3103	0.459178880736	2.35	1.0	0.501	0.481915485015	1.0	0.715682625771	-3.71	0.397	0.668	0.005	None	None	1.32E-05	4.83E-05	0	0	0	None	0	0	1.32E-05	0	0	0	None	N	None
25345	42	D/N	rs776220122	0.1710	gnomAD-4.0.0	44	None	0.49	0.4221	27.4	N	-1.387	0.43	0.021099	-1.639	0.3771	-0.3103	0.459178880736	2.35	1.0	0.501	0.481915485015	1.0	0.715682625771	-3.71	0.397	0.668	0.005	None	None	3.84517E-06	5.07786E-05	0	0	0	None	0	0	3.84517E-06	0	0	0	None	N	None
25347	44	E/D	rs1310471153	0.8965	gnomAD-2.1.1	54	None	0.1172	0.1098	23.5	N	0.076	0.51	0.0136	-0.051	0.0644	-1.1289	0.0777069865228	0.435	0.992732	0.392	0.0611884634855	0.001	0.560344278812	-2.06	0.063	0.228	0.058	None	None	8.05E-06	0	0	0	0	None	6.54E-05	None	8.05E-06	0	0	0	None	I	None
25347	44	E/D	rs1310471153	0.8965	gnomAD-4.0.0	54	None	0.1172	0.1098	23.5	N	0.076	0.51	0.0136	-0.051	0.0644	-1.1289	0.0777069865228	0.435	0.992732	0.392	0.0611884634855	0.001	0.560344278812	-2.06	0.063	0.228	0.058	None	None	8.21205E-06	0	0	0	0	None	0	0	8.21205E-06	0	1.39134E-04	0	None	I	None
25348	45	G/D	None	0.2554	gnomAD-4.0.0	60	None	0.8307	0.8165	28.8	N	None	0.66	0.032567	-0.83	0.2505	-0.5628	0.475819256598	1.8	1.0	0.585	0.338834610459	0.988	0.71012544632	-4.8	0.403	0.589	0.004	None	None	6.84352E-07	0	0	0	0	None	0	0	6.84352E-07	8.99598E-07	0	0	None	N	None
25348	45	G/V	None	0.2554	gnomAD-4.0.0	60	None	0.6454	0.6201	29.1	N	None	0.48	0.034118	-0.49	0.3411	-0.282	0.482130182222	2.435	1.0	0.574	0.495372917472	0.988	0.634143710136	-6.5	0.438	0.683	0.007	None	None	6.84352E-07	0	0	0	0	None	1.87413E-05	0	6.84352E-07	0	0	0	None	N	None
25349	46	I/V	None	0.9695	gnomAD-4.0.0	63	None	0.0813	0.0811	23.6	N	None	0.47	0.00922	-0.361	0.0873	-0.9842	0.0717915256234	-0.11	0.830276	0.383	0.317667799068	0.012	0.576606035233	-0.33	0.06	0.167	0.87	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
25351	48	W/C	rs1195746912	0.2150	gnomAD-4.0.0	65	None	0.9988	0.9984	34.0	N	None	0.44	0.071602	-1.332	0.501	0.1949	0.580146131267	3.755	1.0	0.813	0.473222633396	1.0	0.840722560883	-10.24	0.6	0.663	0.002	None	None	1.59205E-06	0	0	0	2.77778E-05	None	0	0	1.59205E-06	0	0	0	None	N	None
25351	48	W/R	rs201839118	0.2150	gnomAD-2.1.1	65	None	0.9993	0.999	34.0	D	-1.094	0.48	0.258771	-0.963	0.5405	0.4631	0.615612516959	3.755	1.0	0.785	0.820495712062	1.0	0.858627676964	-11.05	0.643	0.723	0.037	None	None	4.65E-05	4.13E-05	0	0	0	None	0	None	4.65E-05	0	9.4E-05	0	None	N	None
25351	48	W/R	rs201839118	0.2150	gnomAD-3.1.2	65	None	0.9993	0.999	34.0	D	-1.094	0.48	0.258771	-0.963	0.5405	0.4631	0.615612516959	3.755	1.0	0.785	0.820495712062	1.0	0.858627676964	-11.05	0.643	0.723	0.037	None	None	5.26E-05	0	0	0	0	None	0	0	5.26E-05	1.17675E-04	0	0	None	N	None
25351	48	W/R	rs201839118	0.2150	gnomAD-4.0.0	65	None	0.9993	0.999	34.0	D	-1.094	0.48	0.258771	-0.963	0.5405	0.4631	0.615612516959	3.755	1.0	0.785	0.820495712062	1.0	0.858627676964	-11.05	0.643	0.723	0.037	None	None	1.28926E-04	1.33529E-05	0	3.37975E-05	0	None	0	0	1.28926E-04	1.62767E-04	0	2.24208E-04	None	N	None
25352	49	T/R	rs1318162597	0.5422	gnomAD-2.1.1	66	None	0.5426	0.5071	34.0	N	-0.236	0.44	0.023621	-0.336	0.2272	-0.6232	0.33750089548	1.645	0.999977	0.493	0.500931478032	0.89	0.651117801666	-4.35	0.319	0.555	0.031	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	I	None
25352	49	T/R	rs1318162597	0.5422	gnomAD-4.0.0	66	None	0.5426	0.5071	34.0	N	-0.236	0.44	0.023621	-0.336	0.2272	-0.6232	0.33750089548	1.645	0.999977	0.493	0.500931478032	0.89	0.651117801666	-4.35	0.319	0.555	0.031	None	None	4.7762E-06	0	0	0	0	None	0	2.41779E-04	4.7762E-06	0	2.86582E-05	0	None	I	None
25352	49	T/S	None	0.5422	gnomAD-4.0.0	66	None	0.1603	0.1712	25.8	N	None	0.42	0.016634	-0.74	0.1515	-0.9248	0.0914627460255	1.47	0.999328	0.425	0.107399877778	0.058	0.593536674976	-2.78	0.133	0.288	0.121	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25353	50	R/G	None	0.5424	gnomAD-4.0.0	67	None	0.8044	0.775	28.0	N	None	0.38	0.056761	-0.595	0.4048	-0.0974	0.523221014711	2.74	0.999999	0.598	0.690070301869	1.0	0.639073371887	-5.25	0.482	0.721	0.004	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25353	50	R/K	None	0.5424	gnomAD-4.0.0	67	None	0.1687	0.183	33.0	N	None	0.42	0.018983	-0.329	0.2115	-0.5857	0.462811898634	0.69	1.0	0.559	0.263140351381	0.997	0.694107115269	-2.1	0.29	0.497	0.19	None	None	1.5921E-06	0	0	0	0	None	0	0	1.5921E-06	0	1.43291E-05	0	None	I	None
25355	52	H/R	rs1399292028	0.5437	gnomAD-2.1.1	69	None	0.338	0.2464	26.6	N	-1.533	0.5	0.018159	-0.46	0.1197	-0.8931	0.153836466492	0.49	0.969378	0.492	0.191931220699	0.285	0.583924651146	-4.56	0.154	0.317	0.013	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	0	1.65782E-04	None	N	None
25355	52	H/R	rs1399292028	0.5437	gnomAD-3.1.2	69	None	0.338	0.2464	26.6	N	-1.533	0.5	0.018159	-0.46	0.1197	-0.8931	0.153836466492	0.49	0.969378	0.492	0.191931220699	0.285	0.583924651146	-4.56	0.154	0.317	0.013	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
25355	52	H/R	rs1399292028	0.5437	gnomAD-4.0.0	69	None	0.338	0.2464	26.6	N	-1.533	0.5	0.018159	-0.46	0.1197	-0.8931	0.153836466492	0.49	0.969378	0.492	0.191931220699	0.285	0.583924651146	-4.56	0.154	0.317	0.013	None	None	3.84518E-06	0	0	0	0	None	0	0	3.84518E-06	7.18243E-06	0	0	None	N	None
25356	53	K/T	rs765495476	1.0668	gnomAD-4.0.0	70	None	0.8653	0.8208	27.7	N	None	0.48	0.040802	0.134	0.2463	-0.6275	0.454903777487	0.925	0.997709	0.551	0.353336612579	0.988	0.669962704182	-4.38	0.309	0.649	0.138	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25357	54	R/C	rs145437410	0.8453	gnomAD-2.1.1	72	None	0.2979	0.2218	None	N	0.003	None	None	0.004	None	None	None	None	None	None	None	0.984	None	None	0.318	0.421	None	None	None	3.22E-05	0	0	0	3.91586E-04	None	0	None	3.22E-05	4.65E-05	0	0	None	I	None
25357	54	R/C	rs145437410	0.8453	gnomAD-3.1.2	72	None	0.2979	0.2218	None	N	0.003	None	None	0.004	None	None	None	None	None	None	None	0.984	None	None	0.318	0.421	None	None	None	6.58E-06	0	0	0	1.93648E-04	None	0	0	6.58E-06	0	0	0	None	I	None
25357	54	R/C	rs145437410	0.8453	1000 genomes	72	None	0.2979	0.2218	None	N	0.003	None	None	0.004	None	None	None	None	None	None	None	0.984	None	None	0.318	0.421	None	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	I	None
25357	54	R/C	rs145437410	0.8453	gnomAD-4.0.0	72	None	0.2979	0.2218	None	N	0.003	None	None	0.004	None	None	None	None	None	None	None	0.984	None	None	0.318	0.421	None	None	None	2.54132E-05	0	0	0	7.59335E-04	None	3.12823E-05	0	2.54132E-05	3.39108E-06	0	1.60092E-05	None	I	None
25357	54	R/H	rs397517703	0.8453	gnomAD-2.1.1	72	None	0.1428	0.1091	None	N	-0.619	None	None	-0.564	None	None	None	None	None	None	None	0.005	None	None	0.071	0.273	None	None	None	3.22E-05	0	0	0	0	None	3.27E-05	None	3.22E-05	0	6.24E-05	0	None	I	None
25357	54	R/H	rs397517703	0.8453	gnomAD-3.1.2	72	None	0.1428	0.1091	None	N	-0.619	None	None	-0.564	None	None	None	None	None	None	None	0.005	None	None	0.071	0.273	None	None	None	1.97E-05	2.41E-05	0	0	0	None	0	0	1.97E-05	2.94E-05	0	0	None	I	None
25357	54	R/H	rs397517703	0.8453	gnomAD-4.0.0	72	None	0.1428	0.1091	None	N	-0.619	None	None	-0.564	None	None	None	None	None	None	None	0.005	None	None	0.071	0.273	None	None	None	1.79761E-05	1.33579E-05	3.336E-05	0	0	None	0	0	1.79761E-05	2.03463E-05	2.19592E-05	0	None	I	None
25357	54	R/P	None	0.8453	gnomAD-4.0.0	72	None	0.7839	0.7091	27.7	N	None	0.65	0.035848	0.475	0.1959	-0.792	0.345421099582	2.36	0.998723	0.629	0.357929162469	0.705	0.599944412708	-4.81	0.22	0.47	0.022	None	None	6.84363E-07	0	2.23674E-05	0	0	None	0	0	6.84363E-07	0	0	0	None	I	None
25358	55	L/V	None	0.3201	gnomAD-4.0.0	75	None	0.0925	0.0964	21.6	N	None	0.38	0.008874	-0.746	0.0855	-1.014	0.0880436698268	0.15	0.98841	0.474	0.141422826196	0.013	0.451491892338	-1.49	0.048	0.135	1.0	None	None	1.59212E-06	0	2.28728E-05	0	0	None	0	0	1.59212E-06	0	0	0	None	N	None
25359	56	I/N	None	0.1235	gnomAD-4.0.0	77	None	0.7088	0.6415	33.0	N	None	0.58	0.056058	-2.1	0.3151	-0.4047	0.53892729574	1.97	0.999915	0.468	0.83719327144	0.99	0.448400557041	-5.32	0.4	0.707	0.001	None	None	6.84349E-07	0	0	0	0	None	0	0	6.84349E-07	8.99594E-07	0	0	None	N	None
25359	56	I/T	rs779076165	0.1235	gnomAD-2.1.1	77	None	0.1586	0.1406	26.1	N	-2.226	0.67	0.041857	-2.4	0.1602	-0.794	0.213063653711	1.355	0.999748	0.421	0.584582053011	0.822	0.474794745445	-3.7	0.253	0.497	0.007	None	None	1.21E-05	0	0	0	0	None	9.81E-05	None	1.21E-05	0	0	0	None	N	None
25359	56	I/T	rs779076165	0.1235	gnomAD-4.0.0	77	None	0.1586	0.1406	26.1	N	-2.226	0.67	0.041857	-2.4	0.1602	-0.794	0.213063653711	1.355	0.999748	0.421	0.584582053011	0.822	0.474794745445	-3.7	0.253	0.497	0.007	None	None	4.1061E-06	0	2.23684E-05	0	0	None	0	0	4.1061E-06	0	5.79737E-05	0	None	N	None
25360	57	G/E	rs1158176682	0.5531	gnomAD-3.1.2	83	None	0.3424	0.3147	24.4	N	None	0.67	0.015787	-0.573	0.0828	-0.8611	0.222558035875	-0.535	0.86046	0.515	0.250039746154	0.521	0.531741201878	-3.46	0.121	0.425	0.157	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
25360	57	G/E	rs1158176682	0.5531	gnomAD-4.0.0	83	None	0.3424	0.3147	24.4	N	None	0.67	0.015787	-0.573	0.0828	-0.8611	0.222558035875	-0.535	0.86046	0.515	0.250039746154	0.521	0.531741201878	-3.46	0.121	0.425	0.157	None	None	6.57583E-06	0	0	0	0	None	0	0	6.57583E-06	1.47115E-05	0	0	None	I	None
25360	57	G/R	None	0.5531	gnomAD-4.0.0	83	None	0.3698	0.3116	23.5	N	None	0.5	0.013543	-0.536	0.07	-0.9267	0.239985301983	-1.015	0.674235	0.514	0.373537453441	0.792	0.551174402237	-4.08	0.178	0.427	0.057	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25362	59	L/F	None	0.2400	gnomAD-4.0.0	89	None	0.5017	0.4503	27.6	N	None	0.48	0.01868	-1.16	0.3205	-0.3759	0.439204412305	2.15	0.999992	0.562	0.452640719197	0.988	0.666851639748	-3.04	0.352	0.754	0.032	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	6.07533E-05	0	None	N	None
25362	59	L/V	rs1409589701	0.2400	gnomAD-3.1.2	89	None	0.1913	0.176	23.5	N	None	0.51	0.009239	-1.085	0.2015	-0.8083	0.319133788807	2.09	0.999673	0.473	0.300110245524	0.919	0.633012831211	-2.22	0.165	0.565	0.084	None	None	6.58E-06	0	0	0	1.93874E-04	None	0	0	6.58E-06	0	0	0	None	N	None
25362	59	L/V	rs1409589701	0.2400	gnomAD-4.0.0	89	None	0.1913	0.176	23.5	N	None	0.51	0.009239	-1.085	0.2015	-0.8083	0.319133788807	2.09	0.999673	0.473	0.300110245524	0.919	0.633012831211	-2.22	0.165	0.565	0.084	None	None	6.58354E-06	0	0	0	1.93874E-04	None	0	0	6.58354E-06	0	0	0	None	N	None
25363	60	R/C	rs757511354	0.6571	gnomAD-2.1.1	90	None	0.5396	0.3724	35.0	N	-0.664	0.3	0.050025	-0.609	0.4012	-0.1294	0.519031115311	2.46	1.0	0.657	0.684613241775	1.0	0.741893112659	-5.81	0.43	0.706	0.001	None	None	1.21E-05	6.46E-05	0	0	0	None	6.54E-05	None	1.21E-05	0	0	0	None	I	None
25363	60	R/C	rs757511354	0.6571	gnomAD-3.1.2	90	None	0.5396	0.3724	35.0	N	-0.664	0.3	0.050025	-0.609	0.4012	-0.1294	0.519031115311	2.46	1.0	0.657	0.684613241775	1.0	0.741893112659	-5.81	0.43	0.706	0.001	None	None	1.32E-05	2.42E-05	0	0	1.94099E-04	None	0	0	1.32E-05	0	0	0	None	I	None
25363	60	R/C	rs757511354	0.6571	gnomAD-4.0.0	90	None	0.5396	0.3724	35.0	N	-0.664	0.3	0.050025	-0.609	0.4012	-0.1294	0.519031115311	2.46	1.0	0.657	0.684613241775	1.0	0.741893112659	-5.81	0.43	0.706	0.001	None	None	2.85157E-05	2.67251E-05	0	0	2.45711E-04	None	0	1.64636E-04	2.85157E-05	2.28894E-05	3.29453E-05	3.20287E-05	None	I	None
25363	60	R/H	rs749274818	0.6571	gnomAD-2.1.1	90	None	0.3173	0.2106	28.5	N	-1.065	0.33	0.028273	-0.845	0.3001	-0.4256	0.495902574493	1.635	0.999904	0.638	0.293147016451	1.0	0.692754089832	-3.34	0.355	0.671	0.058	None	None	2.51E-05	8.27E-05	0	0	0	None	3.27E-05	None	2.51E-05	0	3.14E-05	0	None	I	None
25363	60	R/H	rs749274818	0.6571	gnomAD-3.1.2	90	None	0.3173	0.2106	28.5	N	-1.065	0.33	0.028273	-0.845	0.3001	-0.4256	0.495902574493	1.635	0.999904	0.638	0.293147016451	1.0	0.692754089832	-3.34	0.355	0.671	0.058	None	None	2.63E-05	4.83E-05	6.56E-05	0	0	None	0	0	2.63E-05	1.47E-05	0	0	None	I	None
25363	60	R/H	rs749274818	0.6571	gnomAD-4.0.0	90	None	0.3173	0.2106	28.5	N	-1.065	0.33	0.028273	-0.845	0.3001	-0.4256	0.495902574493	1.635	0.999904	0.638	0.293147016451	1.0	0.692754089832	-3.34	0.355	0.671	0.058	None	None	2.54158E-05	5.34259E-05	1.668E-05	0	0	None	0	0	2.54158E-05	2.79766E-05	2.1964E-05	1.60149E-05	None	I	None
25363	60	R/L	None	0.6571	gnomAD-4.0.0	90	None	0.8181	0.708	27.6	N	None	0.33	0.077326	0.442	0.3666	-0.1898	0.398933509062	2.38	0.999961	0.658	0.644876160298	0.913	0.697574257851	-5.13	0.364	0.599	0.013	None	None	6.84396E-07	0	0	0	0	None	0	0	6.84396E-07	8.99617E-07	0	0	None	I	None
25363	60	R/S	None	0.6571	gnomAD-4.0.0	90	None	0.9231	0.8676	33.0	N	None	0.58	0.057338	-0.767	0.2154	-0.6635	0.350954926724	0.245	0.999907	0.598	0.38342384377	0.913	0.680749535561	-3.94	0.273	0.589	0.15	None	None	1.36879E-06	0	0	0	0	None	0	0	1.36879E-06	1.7992E-06	0	0	None	I	None
25364	61	L/P	rs1707567452	0.2021	gnomAD-4.0.0	91	None	0.9655	0.9547	34.0	N	None	0.28	0.047604	-1.511	0.3562	-0.2496	0.489292874635	1.995	0.999998	0.768	0.776506168477	0.963	0.636435687542	-5.19	0.48	0.659	0.005	None	None	1.59225E-06	0	0	0	0	None	0	0	1.59225E-06	0	1.43312E-05	0	None	I	None
25365	62	R/G	None	0.6072	gnomAD-4.0.0	92	None	0.8021	0.8405	25.7	N	None	0.39	0.035521	-0.607	0.1648	-0.8629	0.111979304278	2.52	0.940976	0.592	0.421550847248	0.008	0.50526535511	-5.41	0.184	0.391	0.02	None	None	1.59223E-06	0	0	0	0	None	0	0	1.59223E-06	0	1.43303E-05	0	None	I	None
25365	62	R/K	None	0.6072	gnomAD-4.0.0	92	None	0.1266	0.179	22.8	N	None	0.48	0.012698	-0.361	0.0884	-1.0002	0.0876846533766	0.245	0.820856	0.531	0.0762999501168	0.008	0.558942198753	-1.67	0.073	0.227	0.75	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25366	63	V/I	None	0.1365	gnomAD-4.0.0	93	None	0.1159	0.1166	24.8	N	None	0.28	0.045762	-0.412	0.1904	-0.7413	0.10609617995	1.265	0.999998	0.484	0.429435026966	0.767	0.644068956375	-0.68	0.174	0.255	0.049	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
25366	63	V/L	rs571834965	0.1365	gnomAD-2.1.1	93	None	0.657	0.6249	28.2	N	-0.463	0.48	0.039194	-0.412	0.2644	-0.6152	0.27893692603	2.11	0.999999	0.592	0.388970301349	0.981	0.754142940044	-2.3	0.292	0.624	0.008	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
25366	63	V/L	rs571834965	0.1365	gnomAD-3.1.2	93	None	0.657	0.6249	28.2	N	-0.463	0.48	0.039194	-0.412	0.2644	-0.6152	0.27893692603	2.11	0.999999	0.592	0.388970301349	0.981	0.754142940044	-2.3	0.292	0.624	0.008	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	0	2.07125E-04	0	None	N	None
25366	63	V/L	rs571834965	0.1365	1000 genomes	93	None	0.657	0.6249	28.2	N	-0.463	0.48	0.039194	-0.412	0.2644	-0.6152	0.27893692603	2.11	0.999999	0.592	0.388970301349	0.981	0.754142940044	-2.3	0.292	0.624	0.008	None	None	1.99681E-04	0	0	None	0	0	None	None	1.99681E-04	None	1E-03	None	None	N	None
25366	63	V/L	rs571834965	0.1365	gnomAD-4.0.0	93	None	0.657	0.6249	28.2	N	-0.463	0.48	0.039194	-0.412	0.2644	-0.6152	0.27893692603	2.11	0.999999	0.592	0.388970301349	0.981	0.754142940044	-2.3	0.292	0.624	0.008	None	None	2.02984E-06	0	0	0	0	None	0	0	2.02984E-06	0	9.39673E-05	0	None	N	None
25367	64	T/I	rs756655305	0.5843	gnomAD-2.1.1	94	None	0.3515	0.2887	None	N	-0.082	None	None	-0.311	None	None	None	None	None	None	None	0.999	None	None	0.456	0.791	None	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.68E-05	0	None	N	None
25367	64	T/I	rs756655305	0.5843	gnomAD-4.0.0	94	None	0.3515	0.2887	None	N	-0.082	None	None	-0.311	None	None	None	None	None	None	None	0.999	None	None	0.456	0.791	None	None	None	1.11467E-05	0	0	0	0	None	0	0	1.11467E-05	2.00191E-05	0	0	None	N	None
25367	64	T/N	None	0.5843	gnomAD-4.0.0	94	None	0.1693	0.1394	34.0	N	None	0.31	0.023671	-0.247	0.4057	-0.2669	0.455635805992	1.81	1.0	0.564	0.46614307118	0.999	0.736413121223	-3.43	0.374	0.633	0.016	None	None	1.59239E-06	0	0	0	2.77901E-05	None	0	0	1.59239E-06	0	0	0	None	N	None
25368	65	G/R	rs551988703	0.4714	gnomAD-3.1.2	96	None	0.8363	0.8038	26.6	N	-0.102	0.06	0.050749	-0.37	0.5033	0.0021	0.506463245118	2.61	1.0	0.726	0.745312688576	1.0	0.825372099876	-5.57	0.588	0.775	0.007	None	None	6.58E-06	0	0	0	1.94024E-04	None	0	0	6.58E-06	0	0	0	None	N	None
25368	65	G/R	rs551988703	0.4714	1000 genomes	96	None	0.8363	0.8038	26.6	N	-0.102	0.06	0.050749	-0.37	0.5033	0.0021	0.506463245118	2.61	1.0	0.726	0.745312688576	1.0	0.825372099876	-5.57	0.588	0.775	0.007	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	N	None
25368	65	G/R	rs551988703	0.4714	gnomAD-4.0.0	96	None	0.8363	0.8038	26.6	N	-0.102	0.06	0.050749	-0.37	0.5033	0.0021	0.506463245118	2.61	1.0	0.726	0.745312688576	1.0	0.825372099876	-5.57	0.588	0.775	0.007	None	None	2.40064E-06	0	0	0	0	None	0	0	2.40064E-06	1.3125E-06	0	3.66327E-05	None	N	None
25368	65	G/V	rs753304499	0.4714	gnomAD-2.1.1	96	None	0.7702	0.7388	29.2	D	0.013	0.04	0.076726	-0.297	0.6465	0.5634	0.518063289252	4.18	1.0	0.716	0.883579667158	1.0	0.77591329813	-6.55	0.622	0.762	0.002	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.93E-06	0	None	N	None
25368	65	G/V	rs753304499	0.4714	gnomAD-4.0.0	96	None	0.7702	0.7388	29.2	D	0.013	0.04	0.076726	-0.297	0.6465	0.5634	0.518063289252	4.18	1.0	0.716	0.883579667158	1.0	0.77591329813	-6.55	0.622	0.762	0.002	None	None	1.59238E-06	0	0	0	0	None	0	0	1.59238E-06	2.85987E-06	0	0	None	N	None
25370	67	I/L	rs751411453	0.4439	gnomAD-2.1.1	98	None	0.0527	0.051	17.94	N	-0.609	0.5	0.008391	-0.83	0.0673	-0.9489	0.0830569285264	0.485	1.0	0.411	0.0716867268079	None	0.370045125484	0.17	0.094	0.097	0.807	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.93E-06	0	None	N	None
25370	67	I/L	rs751411453	0.4439	gnomAD-4.0.0	98	None	0.0527	0.051	17.94	N	-0.609	0.5	0.008391	-0.83	0.0673	-0.9489	0.0830569285264	0.485	1.0	0.411	0.0716867268079	None	0.370045125484	0.17	0.094	0.097	0.807	None	None	1.59254E-06	0	0	0	0	None	0	0	1.59254E-06	2.86026E-06	0	0	None	N	None
25370	67	I/T	rs764131874	0.4439	gnomAD-2.1.1	98	None	0.0758	0.0745	23.9	N	-0.995	0.54	0.034766	-1.304	0.1021	-0.9205	0.122592040068	0.01	0.99336	0.432	0.504113619024	0.117	0.453874349594	-2.52	0.14	0.355	0.318	None	None	4.04E-06	0	0	0	5.6E-05	None	0	None	4.04E-06	0	0	0	None	N	None
25370	67	I/T	rs764131874	0.4439	gnomAD-4.0.0	98	None	0.0758	0.0745	23.9	N	-0.995	0.54	0.034766	-1.304	0.1021	-0.9205	0.122592040068	0.01	0.99336	0.432	0.504113619024	0.117	0.453874349594	-2.52	0.14	0.355	0.318	None	None	6.84439E-06	0	0	0	2.52461E-05	None	0	0	6.84439E-06	7.19721E-06	0	1.65695E-05	None	N	None
25371	68	E/A	None	0.4245	gnomAD-4.0.0	99	None	0.2762	0.2422	33.0	N	None	0.47	0.047599	-0.663	0.3874	-0.1824	0.476869963243	2.515	1.0	0.587	0.415820034956	0.999	0.667491555214	-4.56	0.551	0.632	0.005	None	None	6.84443E-07	0	2.23724E-05	0	0	None	0	0	6.84443E-07	0	0	0	None	N	None
25371	68	E/K	rs755460020	0.4245	gnomAD-2.1.1	99	None	0.3241	0.2923	27.6	N	-0.148	0.37	0.013332	-0.371	0.4104	-0.2131	0.489131336793	2.17	1.0	0.652	0.427368086475	0.999	0.739340424538	-2.85	0.362	0.703	0.005	None	None	4.04E-06	0	0	0	5.6E-05	None	0	None	4.04E-06	0	0	0	None	N	None
25371	68	E/K	rs755460020	0.4245	gnomAD-4.0.0	99	None	0.3241	0.2923	27.6	N	-0.148	0.37	0.013332	-0.371	0.4104	-0.2131	0.489131336793	2.17	1.0	0.652	0.427368086475	0.999	0.739340424538	-2.85	0.362	0.703	0.005	None	None	3.18516E-06	0	0	0	5.55895E-05	None	0	0	3.18516E-06	0	0	0	None	N	None
25371	68	E/Q	None	0.4245	gnomAD-4.0.0	99	None	0.2319	0.1974	26.3	N	None	0.36	0.008494	-0.543	0.3802	-0.3247	0.461673312431	2.675	1.0	0.572	0.371344866733	1.0	0.657697081566	-2.32	0.381	0.681	0.006	None	None	1.59258E-06	0	0	0	2.77948E-05	None	0	0	1.59258E-06	0	0	0	None	N	None
25372	69	N/S	None	0.5748	gnomAD-4.0.0	100	None	0.1008	0.1079	24.6	N	None	0.45	0.018581	-0.429	0.1146	-0.8826	0.0704098353893	0.685	0.523193	0.48	0.154104182512	0.028	0.688704192638	-2.78	0.091	0.269	0.336	None	None	1.36893E-06	0	0	0	0	None	0	0	1.36893E-06	8.99666E-07	1.1599E-05	0	None	N	None
25373	70	H/Q	rs764739209	0.3363	gnomAD-2.1.1	102	None	0.442	0.4137	26.7	N	-0.625	0.49	0.014293	-0.255	0.1692	-0.91	0.393664368159	1.505	0.884962	0.482	0.251639045875	0.951	0.667086601257	-4.89	0.246	0.376	0.241	None	None	4.04E-06	0	0	0	0	None	3.27E-05	None	4.04E-06	0	0	0	None	N	None
25373	70	H/Q	rs764739209	0.3363	gnomAD-4.0.0	102	None	0.442	0.4137	26.7	N	-0.625	0.49	0.014293	-0.255	0.1692	-0.91	0.393664368159	1.505	0.884962	0.482	0.251639045875	0.951	0.667086601257	-4.89	0.246	0.376	0.241	None	None	3.4227E-06	0	0	0	0	None	0	0	3.4227E-06	0	4.64048E-05	1.65728E-05	None	N	None
25374	71	D/G	None	0.2260	gnomAD-4.0.0	103	None	0.1978	0.1811	23.5	N	None	0.39	0.024375	-1.45	0.1026	-0.9831	0.118486349689	0.53	0.999536	0.541	0.178374595973	0.012	0.315398395061	-1.23	0.078	0.389	0.188	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
25374	71	D/H	None	0.2260	gnomAD-4.0.0	103	None	0.1515	0.1148	23.3	N	None	0.38	0.021757	-1.073	0.1097	-0.9073	0.100364261058	1.975	1.0	0.517	0.0482279557977	0.001	0.330314725637	-1.09	0.104	0.291	0.064	None	None	6.84549E-07	0	0	0	0	None	0	0	6.84549E-07	0	1.16025E-05	0	None	N	None
25374	71	D/N	rs368715583	0.2260	gnomAD-2.1.1	103	None	0.0698	0.0669	None	N	-1.695	None	None	-1.836	None	None	None	None	None	None	None	None	None	None	0.116	0.107	None	None	None	1.21E-05	6.46E-05	0	0	0	None	3.27E-05	None	1.21E-05	0	8.94E-06	0	None	N	None
25374	71	D/N	rs368715583	0.2260	gnomAD-3.1.2	103	None	0.0698	0.0669	None	N	-1.695	None	None	-1.836	None	None	None	None	None	None	None	None	None	None	0.116	0.107	None	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
25374	71	D/N	rs368715583	0.2260	gnomAD-4.0.0	103	None	0.0698	0.0669	None	N	-1.695	None	None	-1.836	None	None	None	None	None	None	None	None	None	None	0.116	0.107	None	None	None	1.11604E-05	4.00769E-05	0	0	0	None	0	0	1.11604E-05	1.01748E-05	2.19751E-05	1.60185E-05	None	N	None
25375	72	Y/F	rs374494927	0.0954	gnomAD-2.1.1	104	None	0.2341	0.2027	None	D	-1.334	None	None	-1.389	None	None	None	None	None	None	None	0.999	None	None	0.797	0.745	None	None	None	3.23E-05	6.46E-05	1.45332E-04	0	0	None	0	None	3.23E-05	0	8.94E-06	1.66611E-04	None	N	None
25375	72	Y/F	rs374494927	0.0954	gnomAD-3.1.2	104	None	0.2341	0.2027	None	D	-1.334	None	None	-1.389	None	None	None	None	None	None	None	0.999	None	None	0.797	0.745	None	None	None	6.58E-06	0	6.56E-05	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
25375	72	Y/F	rs374494927	0.0954	gnomAD-4.0.0	104	None	0.2341	0.2027	None	D	-1.334	None	None	-1.389	None	None	None	None	None	None	None	0.999	None	None	0.797	0.745	None	None	None	8.05959E-06	1.33568E-05	1.16791E-04	0	0	None	0	0	8.05959E-06	1.69572E-06	0	4.80523E-05	None	N	None
25379	76	V/I	None	0.0693	gnomAD-4.0.0	108	None	0.1101	0.1157	29.6	N	None	-0.51	0.015969	-1.094	0.5416	0.0454	0.420894402933	1.82	1.0	0.787	0.774835214283	0.997	0.586986839771	-0.79	0.414	0.657	0.009	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
25381	78	A/T	rs763636099	0.0806	gnomAD-2.1.1	110	None	0.7678	0.6986	26.7	D	-2.004	-1.02	0.028817	-2.032	0.7665	0.7214	0.457598942377	3.765	1.0	0.792	0.656398299794	1.0	0.688975453377	-3.37	0.603	0.786	None	None	None	8.09E-06	0	2.91E-05	0	0	None	0	None	8.09E-06	0	8.96E-06	0	None	N	None
25381	78	A/T	rs763636099	0.0806	gnomAD-3.1.2	110	None	0.7678	0.6986	26.7	D	-2.004	-1.02	0.028817	-2.032	0.7665	0.7214	0.457598942377	3.765	1.0	0.792	0.656398299794	1.0	0.688975453377	-3.37	0.603	0.786	None	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
25381	78	A/T	rs763636099	0.0806	gnomAD-4.0.0	110	None	0.7678	0.6986	26.7	D	-2.004	-1.02	0.028817	-2.032	0.7665	0.7214	0.457598942377	3.765	1.0	0.792	0.656398299794	1.0	0.688975453377	-3.37	0.603	0.786	None	None	None	4.96216E-06	6.68217E-05	3.33934E-05	0	0	None	0	0	4.96216E-06	8.48241E-07	0	0	None	N	None
25384	81	A/T	None	0.5917	gnomAD-4.0.0	113	None	0.1023	0.1201	28.6	N	None	0.43	0.034911	-0.627	0.3703	-0.3585	0.457598942377	1.555	1.0	0.394	0.473538153929	1.0	0.700508832932	-2.85	0.308	0.699	0.014	None	None	2.73967E-06	0	0	0	0	None	0	0	2.73967E-06	3.60086E-06	0	0	None	I	None
25387	84	L/F	rs879225322	0.3371	gnomAD-3.1.2	117	None	0.1189	0.1119	None	N	None	None	None	-1.093	None	None	None	None	None	None	None	0.942	None	None	0.186	0.691	None	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	0	0	4.78011E-04	None	I	None
25387	84	L/F	rs879225322	0.3371	gnomAD-4.0.0	117	None	0.1189	0.1119	None	N	None	None	None	-1.093	None	None	None	None	None	None	None	0.942	None	None	0.186	0.691	None	None	None	4.3417E-06	0	0	0	0	None	0	0	4.3417E-06	4.241E-06	0	1.60267E-05	None	I	None
25387	84	L/I	None	0.3371	gnomAD-4.0.0	117	None	0.0756	0.0808	23.2	N	None	0.58	0.005176	-0.768	0.0788	-1.0224	0.0992374294878	-0.03	0.977202	0.352	0.371344866733	0.058	0.56547999382	-0.81	0.055	0.296	0.716	None	None	6.84812E-07	0	0	0	0	None	0	0	6.84812E-07	0	1.16063E-05	0	None	I	None
25388	85	S/R	rs1707543874	0.0817	gnomAD-4.0.0	118	None	0.9963	0.9963	27.9	N	None	0.33	0.033754	-0.741	0.3704	-0.3095	0.395548173852	3.3	0.999286	0.576	0.301455362545	0.939	0.620541155338	-3.56	0.411	0.781	0.048	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	0	3.66354E-05	None	N	None
25388	85	S/T	None	0.0817	gnomAD-4.0.0	118	None	0.718	0.7557	24.6	N	None	0.38	0.034917	-0.947	0.3828	-0.1348	0.292063610931	3.3	0.999995	0.536	0.317958651998	0.815	0.570568203926	-2.29	0.385	0.7	0.107	None	None	7.20193E-06	0	0	0	0	None	0	0	7.20193E-06	7.87501E-06	0	0	None	N	None
25389	86	E/D	rs371435213	0.6610	gnomAD-2.1.1	119	None	0.0957	0.1028	22.5	N	-0.039	0.36	0.015854	-0.322	0.132	-0.971	0.15899387495	1.535	0.999022	0.333	0.297031009988	0.447	0.529332399368	-2.22	0.115	0.431	0.078	None	None	4.05E-06	6.47E-05	0	0	0	None	0	None	4.05E-06	0	0	0	None	I	None
25389	86	E/D	rs371435213	0.6610	gnomAD-3.1.2	119	None	0.0957	0.1028	22.5	N	-0.039	0.36	0.015854	-0.322	0.132	-0.971	0.15899387495	1.535	0.999022	0.333	0.297031009988	0.447	0.529332399368	-2.22	0.115	0.431	0.078	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	I	None
25389	86	E/D	rs371435213	0.6610	gnomAD-4.0.0	119	None	0.0957	0.1028	22.5	N	-0.039	0.36	0.015854	-0.322	0.132	-0.971	0.15899387495	1.535	0.999022	0.333	0.297031009988	0.447	0.529332399368	-2.22	0.115	0.431	0.078	None	None	6.57834E-06	2.41359E-05	0	0	0	None	0	0	6.57834E-06	0	0	0	None	I	None
25389	86	E/G	None	0.6610	gnomAD-4.0.0	119	None	0.1225	0.1212	27.9	N	None	0.42	0.061977	-0.648	0.1869	-0.7116	0.151893044679	2.305	0.999432	0.464	0.303453137403	0.491	0.486178636551	-4.88	0.209	0.464	0.017	None	None	1.59487E-06	0	0	0	0	None	0	0	1.59487E-06	2.86535E-06	0	0	None	I	None
25389	86	E/K	None	0.6610	gnomAD-4.0.0	119	None	0.0859	0.0816	23.4	N	None	0.39	0.016246	0.35	0.1486	-0.9309	0.0983039149079	0.665	0.999762	0.49	0.229924730088	0.005	0.615580439568	-2.27	0.113	0.151	0.312	None	None	1.59537E-06	0	0	0	0	None	0	0	1.59537E-06	2.8662E-06	0	0	None	I	None
25390	87	P/L	rs775467614	0.2952	gnomAD-2.1.1	120	None	0.1862	0.1629	33.0	N	-0.701	0.52	0.02439	-0.945	0.3828	-0.2184	0.386209809726	2.925	1.0	0.515	0.551467209619	0.976	0.686256945133	-7.2	0.501	0.78	0.034	None	None	8.1E-06	0	0	0	5.61E-05	None	3.28E-05	None	8.1E-06	0	0	0	None	I	None
25390	87	P/L	rs775467614	0.2952	gnomAD-4.0.0	120	None	0.1862	0.1629	33.0	N	-0.701	0.52	0.02439	-0.945	0.3828	-0.2184	0.386209809726	2.925	1.0	0.515	0.551467209619	0.976	0.686256945133	-7.2	0.501	0.78	0.034	None	None	3.19006E-06	0	0	0	2.78118E-05	None	0	0	3.19006E-06	0	1.43546E-05	0	None	I	None
25390	87	P/S	rs878948198	0.2952	gnomAD-2.1.1	120	None	0.2142	0.1946	None	N	-1.078	None	None	-1.36	None	None	None	None	None	None	None	0.976	None	None	0.418	0.696	None	None	None	1.21E-05	0	2.91E-05	0	0	None	0	None	1.21E-05	0	1.79E-05	0	None	I	None
25390	87	P/S	rs878948198	0.2952	gnomAD-3.1.2	120	None	0.2142	0.1946	None	N	-1.078	None	None	-1.36	None	None	None	None	None	None	None	0.976	None	None	0.418	0.696	None	None	None	1.32E-05	0	0	0	0	None	0	0	1.32E-05	2.94E-05	0	0	None	I	None
25390	87	P/S	rs878948198	0.2952	gnomAD-4.0.0	120	None	0.2142	0.1946	None	N	-1.078	None	None	-1.36	None	None	None	None	None	None	None	0.976	None	None	0.418	0.696	None	None	None	5.08679E-05	0	0	0	0	None	0	0	5.08679E-05	6.70153E-05	0	4.80846E-05	None	I	None
25390	87	P/T	None	0.2952	gnomAD-4.0.0	120	None	0.2069	0.1842	31.0	N	None	0.45	0.044657	-1.316	0.4334	0.1785	0.404200949522	3.38	0.999999	0.402	0.417081434665	0.988	0.665378987789	-5.77	0.449	0.704	0.063	None	None	2.05472E-06	0	0	0	0	None	0	0	2.05472E-06	2.70057E-06	0	0	None	I	None
25391	88	S/I	None	0.0903	gnomAD-4.0.0	121	None	0.9726	0.9604	29.9	D	None	-0.55	0.059091	0.085	0.7437	0.7696	0.503214603424	4.0	1.0	0.541	0.719532834518	1.0	0.585239589214	-4.85	0.597	0.891	0.001	None	None	1.59509E-06	0	0	0	0	None	0	0	1.59509E-06	2.86554E-06	0	0	None	N	None
25391	88	S/R	None	0.0903	gnomAD-4.0.0	121	None	0.9983	0.9977	26.6	D	None	-0.51	0.050607	-0.935	0.6106	0.1968	0.489826376215	4.0	0.999958	0.556	0.435808882951	1.0	0.611279070377	-4.02	0.692	0.876	0.003	None	None	6.84885E-07	0	0	0	0	None	0	0	6.84885E-07	9.0016E-07	0	0	None	N	None
25392	89	P/H	None	0.4996	gnomAD-4.0.0	122	None	0.1159	0.1078	23.4	N	None	0.53	0.032932	-0.728	0.1798	-0.7369	0.113738120051	1.31	0.705939	0.235	0.165133752707	0.162	0.379224896431	-5.43	0.182	0.395	0.014	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	I	None
25393	90	P/S	rs1005590673	0.3347	gnomAD-4.0.0	123	None	0.1195	0.1158	23.3	N	None	0.51	0.01309	-1.482	0.1468	-0.9173	0.0909588191356	0.945	0.996562	0.249	0.165133752707	0.18	0.503061532974	-5.03	0.164	0.372	0.187	None	None	3.18885E-06	0	4.57917E-05	0	0	None	0	0	3.18885E-06	0	0	0	None	N	None
25395	92	A/V	rs1311650365	0.6458	gnomAD-3.1.2	125	None	0.0699	0.0667	26.7	N	None	0.65	0.004895	-0.272	0.0562	-1.0645	0.0828984465545	0.665	0.914876	0.266	0.198526703765	None	0.3606133461	-1.32	0.109	0.125	0.526	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
25395	92	A/V	rs1311650365	0.6458	gnomAD-4.0.0	125	None	0.0699	0.0667	26.7	N	None	0.65	0.004895	-0.272	0.0562	-1.0645	0.0828984465545	0.665	0.914876	0.266	0.198526703765	None	0.3606133461	-1.32	0.109	0.125	0.526	None	None	6.578E-06	0	0	0	0	None	0	0	6.578E-06	1.47132E-05	0	0	None	N	None
25396	93	Y/D	rs771853872	0.3325	gnomAD-2.1.1	126	None	0.4447	0.469	26.7	N	-0.285	0.58	0.022247	0.116	0.1862	-0.7948	0.307476924182	1.645	0.999879	0.417	0.485846224565	0.808	0.670132696629	-6.98	0.308	0.717	0.057	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.95E-06	0	None	N	None
25396	93	Y/D	rs771853872	0.3325	gnomAD-4.0.0	126	None	0.4447	0.469	26.7	N	-0.285	0.58	0.022247	0.116	0.1862	-0.7948	0.307476924182	1.645	0.999879	0.417	0.485846224565	0.808	0.670132696629	-6.98	0.308	0.717	0.057	None	None	1.59362E-06	0	0	0	0	None	0	0	1.59362E-06	2.86231E-06	0	0	None	N	None
25398	95	K/M	None	0.2849	gnomAD-4.0.0	129	None	0.2916	0.28	34.0	N	None	0.61	0.034947	0.486	0.2311	-0.6475	0.459495559308	2.455	0.999953	0.453	0.284539287134	0.997	0.635030865669	-4.07	0.293	0.685	0.013	None	None	1.5933E-06	0	0	0	0	None	0	0	1.5933E-06	2.86175E-06	0	0	None	N	None
25398	95	K/R	rs1467808986	0.2849	gnomAD-2.1.1	129	None	0.0823	0.0858	27.3	N	0.198	0.62	0.012175	-0.64	0.1152	-1.0088	0.0721994706003	0.385	0.99937	0.341	0.218845423259	0.027	0.630928635597	-2.17	0.066	0.359	0.072	None	None	4.04E-06	0	0	0	5.61E-05	None	0	None	4.04E-06	0	0	0	None	N	None
25398	95	K/R	rs1467808986	0.2849	gnomAD-4.0.0	129	None	0.0823	0.0858	27.3	N	0.198	0.62	0.012175	-0.64	0.1152	-1.0088	0.0721994706003	0.385	0.99937	0.341	0.218845423259	0.027	0.630928635597	-2.17	0.066	0.359	0.072	None	None	1.5933E-06	0	0	0	2.78025E-05	None	0	0	1.5933E-06	0	0	0	None	N	None
25399	96	A/P	rs1179236670	0.0654	gnomAD-2.1.1	130	None	0.786	0.8109	29.7	N	-1.007	0.59	0.008964	-0.851	0.3703	-0.3585	0.524585786375	2.71	1.0	0.344	0.57786441613	1.0	0.619674682617	-3.77	0.362	0.826	0.01	None	None	3.19E-05	1.14837E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	N	None
25399	96	A/P	rs1179236670	0.0654	gnomAD-3.1.2	130	None	0.786	0.8109	29.7	N	-1.007	0.59	0.008964	-0.851	0.3703	-0.3585	0.524585786375	2.71	1.0	0.344	0.57786441613	1.0	0.619674682617	-3.77	0.362	0.826	0.01	None	None	6.58E-06	2.41E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
25399	96	A/P	rs1179236670	0.0654	gnomAD-4.0.0	130	None	0.786	0.8109	29.7	N	-1.007	0.59	0.008964	-0.851	0.3703	-0.3585	0.524585786375	2.71	1.0	0.344	0.57786441613	1.0	0.619674682617	-3.77	0.362	0.826	0.01	None	None	6.57947E-06	2.41453E-05	0	0	0	None	0	0	6.57947E-06	0	0	0	None	N	None
25399	96	A/T	None	0.0654	gnomAD-4.0.0	130	None	0.7467	0.7453	29.4	N	None	0.53	0.008431	-1.854	0.3045	-0.5363	0.456114532304	1.76	1.0	0.249	0.500805711387	1.0	0.576262116432	-2.99	0.28	0.766	0.015	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	0	6.07533E-05	0	None	N	None
25399	96	A/V	rs1418217582	0.0654	gnomAD-2.1.1	130	None	0.5814	0.6068	34.0	N	-0.385	0.53	0.014431	-0.851	0.3198	-0.5031	0.460764587813	2.175	1.0	0.312	0.566810639971	0.999	0.580219626427	-2.89	0.327	0.677	0.039	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.49E-05	0	None	N	None
25399	96	A/V	rs1418217582	0.0654	gnomAD-3.1.2	130	None	0.5814	0.6068	34.0	N	-0.385	0.53	0.014431	-0.851	0.3198	-0.5031	0.460764587813	2.175	1.0	0.312	0.566810639971	0.999	0.580219626427	-2.89	0.327	0.677	0.039	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
25399	96	A/V	rs1418217582	0.0654	gnomAD-4.0.0	130	None	0.5814	0.6068	34.0	N	-0.385	0.53	0.014431	-0.851	0.3198	-0.5031	0.460764587813	2.175	1.0	0.312	0.566810639971	0.999	0.580219626427	-2.89	0.327	0.677	0.039	None	None	6.57652E-06	0	0	0	0	None	0	0	6.57652E-06	1.47124E-05	0	0	None	N	None
25400	97	C/R	rs1575727915	0.2725	gnomAD-4.0.0	131	None	0.1461	0.1275	23.5	N	None	0.35	0.019647	-0.639	0.1	-1.0316	0.150935704758	-0.24	0.999857	0.401	0.40218521252	0.001	0.597903549671	-6.28	0.319	0.231	0.825	None	None	1.59287E-06	0	0	0	0	None	0	0	1.59287E-06	2.86077E-06	0	0	None	N	None
25400	97	C/S	rs397517704	0.2725	gnomAD-2.1.1	131	None	0.1286	0.1249	23.1	N	-0.534	0.37	0.015056	-1.107	0.1287	-0.9191	0.103270580203	1.175	0.808397	0.435	0.350307294319	0.003	0.50554561615	-5.36	0.304	0.154	0.523	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.49E-05	0	None	N	None
25400	97	C/S	rs397517704	0.2725	gnomAD-3.1.2	131	None	0.1286	0.1249	23.1	N	-0.534	0.37	0.015056	-1.107	0.1287	-0.9191	0.103270580203	1.175	0.808397	0.435	0.350307294319	0.003	0.50554561615	-5.36	0.304	0.154	0.523	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
25400	97	C/S	rs397517704	0.2725	gnomAD-4.0.0	131	None	0.1286	0.1249	23.1	N	-0.534	0.37	0.015056	-1.107	0.1287	-0.9191	0.103270580203	1.175	0.808397	0.435	0.350307294319	0.003	0.50554561615	-5.36	0.304	0.154	0.523	None	None	1.05401E-05	0	0	0	0	None	0	0	1.05401E-05	1.3566E-05	0	1.60226E-05	None	N	None
25400	97	C/W	None	0.2725	gnomAD-4.0.0	131	None	0.3358	0.3225	33.0	N	None	0.26	0.054331	-1.027	0.264	-0.5241	0.249498265086	2.07	0.999997	0.335	0.277317399466	0.973	0.564181566238	-6.45	0.286	0.527	0.05	None	None	6.37135E-06	0	0	0	0	None	0	0	6.37135E-06	1.14429E-05	0	0	None	N	None
25401	98	D/E	None	0.4459	gnomAD-4.0.0	132	None	0.5294	0.6488	27.0	N	None	1.11	0.017185	-0.352	0.1919	-0.7846	0.446550992324	2.55	0.999997	0.275	0.208816687407	0.999	0.604460477829	-3.13	0.108	0.469	0.117	None	None	1.59274E-06	0	0	0	0	None	0	0	1.59274E-06	2.86049E-06	0	0	None	N	None
25401	98	D/V	rs1559385033	0.4459	gnomAD-2.1.1	132	None	0.7042	0.8092	34.0	N	0.334	1.15	0.04774	0.03	0.2645	-0.4996	0.550621287307	3.705	1.0	0.489	0.376921832658	1.0	0.571192979813	-6.75	0.596	0.759	0.001	None	None	4.04E-06	0	0	0	0	None	3.28E-05	None	4.04E-06	0	0	0	None	N	None
25401	98	D/V	rs1559385033	0.4459	gnomAD-4.0.0	132	None	0.7042	0.8092	34.0	N	0.334	1.15	0.04774	0.03	0.2645	-0.4996	0.550621287307	3.705	1.0	0.489	0.376921832658	1.0	0.571192979813	-6.75	0.596	0.759	0.001	None	None	3.18564E-06	0	0	0	0	None	0	0	3.18564E-06	0	2.86812E-05	0	None	N	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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